المؤلفون: Yoko Marwidi, Hoang-Oanh B. Nguyen, David Santos, Tenzin Wangzor, Sumita Bhardwaj, Gabriel Ernie, Gregg Prawdzik, Garrett Lew, David Shivak, Michael Trias, Jada Padilla, Hung Tran, Kathleen Meyer, Richard Surosky, Alex Michael Ward

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101228- (2024)

مصطلحات موضوعية: AAV, baculovirus, Sf9 cells, capsid engineering, gene therapy, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050124000445; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/cc8de2e15a6c4613942f48ea926bb8b5

المؤلفون: Yasaman Ataei, Larry Park, D. James Surmeier, B. Joseph Vu, Seung Kwak, Richard T. Surosky, Anand Narayanan, David A. Shivak, Josee Laganiere, Christer Halldin, Andrea Varrone, Matthew C. Mendel, Karsten Tillack, Lei Zhang, Bryan Zeitler, Dmitry Guschin, Lexi Kopan, Sarah J. Hinkley, Kimberly Marlen, Jocelynn R. Pearl, Qi Yu, Taneli Heikkinen, Annette Gärtner, Yalda Sedaghat, Christina Thiede, Miklós Tóth, Jennifer M. Cherone, David Paschon, Jyothisri Kondapalli, Andrea E. Kudwa, Ladislav Mrzljak, Rainier Amora, Kimmo Lehtimäki, Edward J. Rebar, Lenke Tari, Ignacio Munoz-Sanjuan, Jeffrey C. Miller, Sylvie Ramboz, Marie Svedberg, Steven Froelich, Irina Ankoudinova, Philip D. Gregory, Stephen Lam, Michelle Day, Jonathan Bard, Hoang Oanh B. Nguyen, Fyodor D. Urnov, Davis Li, Jenny Haggkvist, H. Steve Zhang, Guijuan Qiao

المصدر: Nature Medicine. 25:1131-1142

مصطلحات موضوعية: 0301 basic medicine, Zinc finger, congenital, hereditary, and neonatal diseases and abnormalities, Mutant, General Medicine, Biology, medicine.disease, General Biochemistry, Genetics and Molecular Biology, nervous system diseases, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Huntington's disease, Transcription (biology), 030220 oncology & carcinogenesis, mental disorders, medicine, Gene silencing, Allele, Gene, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d19307c1ae395108f0cf1b74fb590fb6
https://doi.org/10.1038/s41591-019-0478-3

المؤلفون: Susanne Wegmann, Bradley T. Hyman, Annemarie Ledeboer, Jeffrey C. Miller, Marta Perez-Rando, Kimberly Marlen, Richard T. Surosky, Bryan Zeitler, Caitlin Commins, Alison Chase, Michael C. Holmes, Sarah J. Hinkley, Alicia Goodwin, Riley N. Bannon, Lei Zhang, Brigit E. Riley, Hoang-Oanh B. Nguyen, Sarah L. DeVos, Edward J. Rebar, Ashley B. Robbins, Stephen Lam, Rainier Amora, Irina Ankoudinova, Qi Yu, Amy M. Pooler, Hung Tran, Nicholas A. Scarlott, Bianca T. Corjuc, Danny MacKenzie, Fyodor D. Urnov, H. Steve Zhang, Lisa Diez, Rachel E. Bennett

المصدر: Science advances 7(12), eabe1611-(2021). doi:10.1126/sciadv.abe1611
Science Advances

مصطلحات موضوعية: Endogeny, Plaque, Amyloid, genetics [Alzheimer Disease], genetics [Dependovirus], Transduction (genetics), pathology [Alzheimer Disease], Mice, 0302 clinical medicine, Research Methods, metabolism [Transcription Factors], genetics [Zinc Fingers], Research Articles, Zinc finger, 0303 health sciences, Gene knockdown, Multidisciplinary, Chemistry, Brain, SciAdv r-articles, Zinc Fingers, Human brain, Dependovirus, genetics [Transcription Factors], Cell biology, medicine.anatomical_structure, ddc:500, Research Article, metabolism [Amyloid beta-Peptides], tau Proteins, 03 medical and health sciences, Alzheimer Disease, mental disorders, medicine, Animals, pathology [Plaque, Amyloid], Transcription factor, 030304 developmental biology, Messenger RNA, Amyloid beta-Peptides, therapy [Alzheimer Disease], Neurotoxicity, medicine.disease, metabolism [tau Proteins], Disease Models, Animal, genetics [tau Proteins], metabolism [Brain], metabolism [Dependovirus], 030217 neurology & neurosurgery, Transcription Factors, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1e249560ae8a0539e415f467dba78e

المؤلفون: David W Colby, Rachel Wain, Ilia V Baskakov, Giuseppe Legname, Christina G Palmer, Hoang-Oanh B Nguyen, Azucena Lemus, Fred E Cohen, Stephen J DeArmond, Stanley B Prusiner

المصدر: PLoS Pathogens, Vol 6, Iss 1, p e1000736 (2010)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2809756?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/05d2fdbcce8f465787a434786e853dd7

المؤلفون: Bryan, Zeitler, Steven, Froelich, Kimberly, Marlen, David A, Shivak, Qi, Yu, Davis, Li, Jocelynn R, Pearl, Jeffrey C, Miller, Lei, Zhang, David E, Paschon, Sarah J, Hinkley, Irina, Ankoudinova, Stephen, Lam, Dmitry, Guschin, Lexi, Kopan, Jennifer M, Cherone, Hoang-Oanh B, Nguyen, Guijuan, Qiao, Yasaman, Ataei, Matthew C, Mendel, Rainier, Amora, Richard, Surosky, Josee, Laganiere, B Joseph, Vu, Anand, Narayanan, Yalda, Sedaghat, Karsten, Tillack, Christina, Thiede, Annette, Gärtner, Seung, Kwak, Jonathan, Bard, Ladislav, Mrzljak, Larry, Park, Taneli, Heikkinen, Kimmo K, Lehtimäki, Marie M, Svedberg, Jenny, Häggkvist, Lenke, Tari, Miklós, Tóth, Andrea, Varrone, Christer, Halldin, Andrea E, Kudwa, Sylvie, Ramboz, Michelle, Day, Jyothisri, Kondapalli, D James, Surmeier, Fyodor D, Urnov, Philip D, Gregory, Edward J, Rebar, Ignacio, Muñoz-Sanjuán, H Steve, Zhang

المصدر: Nature medicine. 25(7)

مصطلحات موضوعية: Male, Huntingtin Protein, Transcription, Genetic, Zinc Fingers, Neuroprotection, Mice, Inbred C57BL, Disease Models, Animal, Mice, Huntington Disease, Trinucleotide Repeats, Mutation, Mice, Inbred CBA, Animals, Humans, Female, Alleles, Cells, Cultured

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4d3620bad8fe21aa64bd37ef53578561
https://pubmed.ncbi.nlm.nih.gov/31263285

المؤلفون: Giuseppe Legname, Stephen J. DeArmond, Holger Wille, Hoang-Oanh B. Nguyen, Joel C. Watts, Azucena Lemus, Joshua Sussman, Kurt Giles, Jan Stöhr, Abby Oehler, Stanley B. Prusiner

المصدر: Proceedings of the National Academy of Sciences. 108:21223-21228

مصطلحات موضوعية: Genetically modified mouse, Amyloid, Protein Folding, Disease onset, Glycosylphosphatidylinositols, animal diseases, Blotting, Western, Mice, Transgenic, Biology, Mice, neurodegenerative disease, Microscopy, Electron, Transmission, Animals, Gerstmann-Straussler-Scheinker Disease, PrPC Proteins, protein misfolding, amyloidosis, Multidisciplinary, proteinopathies, Histological Techniques, Disease progression, Biological Sciences, Molecular biology, nervous system diseases, Disease Models, Animal, Amyloid deposition, Epitope mapping, Electrophoresis, Polyacrylamide Gel, Protein folding, Epitope Mapping, Glycosylphosphatidyl inositol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47a2950cb664478ff6938a7cc1b681d
https://doi.org/10.1073/pnas.1117827108

المؤلفون: Joel C. Watts, Sina Ghaemmaghami, Stephen J. DeArmond, Hoang-Oanh B. Nguyen, Shigenari Hayashi, Stanley B. Prusiner

المصدر: Journal of Molecular Biology. 413:527-542

مصطلحات موضوعية: Male, Amyloid, Prions, Protein Conformation, Blotting, Western, Population, Mice, Transgenic, Biology, Mice, Neuroblastoma, Protein structure, Structural Biology, Endopeptidases, Tumor Cells, Cultured, Animals, Selection, Genetic, education, Molecular Biology, education.field_of_study, Molecular mass, Strain (chemistry), Brain, Fungal prion, Transformation (genetics), Biochemistry, Nucleic acid, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e80499e1fcd8cc961d55d16d2f00398
https://doi.org/10.1016/j.jmb.2011.07.021

المؤلفون: Hoang-Oanh B. Nguyen, Frederick Cohen, Stephen J. DeArmond, David Peretz, Giuseppe Legname, Stanley B. Prusiner

المصدر: Proceedings of the National Academy of Sciences. 103:19105-19110

مصطلحات موضوعية: Genetics, Multidisciplinary, Prions, Protein Conformation, animal diseases, Biological Sciences, Biology, Phenotype, nervous system diseases, Prion Diseases, Incubation period, Survival Rate, Mice, chemistry.chemical_compound, Linear relationship, Protein structure, chemistry, Biochemistry, Animals, Prion protein, Guanidine, Incubation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9976df9d9aecacbdc6315d0fc3ac8be
https://doi.org/10.1073/pnas.0608970103

المؤلفون: Stephen J. DeArmond, David Peretz, Stanley B. Prusiner, Michael R. Scott, Hoang-Oanh B. Nguyen

المصدر: Scott, Michael R; Peretz, David; Nguyen, Hoang-Oanh B; Dearmond, Stephen J; & Prusiner, Stanley B. (2005). Transmission barriers for bovine ovine, and human prions in transgenic mice. Journal of Virology, 79(9), 5259-5271. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6xv0v7kk

مصطلحات موضوعية: Genetically modified mouse, PrPSc Proteins, Prions, Ratón, animal diseases, Transgene, Bovine spongiform encephalopathy, Immunology, Mice, Transgenic, Scrapie, Biology, Microbiology, Creutzfeldt-Jakob Syndrome, Mice, Species Specificity, Virology, mental disorders, medicine, Animals, Humans, Sheep, Brain, medicine.disease, nervous system diseases, Encephalopathy, Bovine Spongiform, Disease Models, Animal, Insect Science, Pathogenesis and Immunity, Cattle, Disease Susceptibility, Conformational stability

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8d977395e010c093a91e39e507d2aa
https://doi.org/10.1128/jvi.79.9.5259-5271.2005

المؤلفون: James W. Ironside, Patrick Tremblay, Michael R. Scott, Stephen J. DeArmond, Robert G. Will, Stanley B. Prusiner, Hoang-Oanh B. Nguyen

المصدر: Proceedings of the National Academy of Sciences. 96:15137-15142

مصطلحات موضوعية: Risk, PrPSc Proteins, Prions, animal diseases, Transgene, Bovine spongiform encephalopathy, Mice, Transgenic, Scrapie, Neuropathology, Biology, Creutzfeldt-Jakob Syndrome, Mice, Species Specificity, mental disorders, medicine, Animals, Humans, Tissue Distribution, Multidisciplinary, Transmission (medicine), Neurodegeneration, Brain, Biological Sciences, medicine.disease, Virology, nervous system diseases, Encephalopathy, Bovine Spongiform, Cattle

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a3d558f0bcbfbc382143824f0ff927
https://doi.org/10.1073/pnas.96.26.15137