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1دورية أكاديمية
المؤلفون: Yoko Marwidi, Hoang-Oanh B. Nguyen, David Santos, Tenzin Wangzor, Sumita Bhardwaj, Gabriel Ernie, Gregg Prawdzik, Garrett Lew, David Shivak, Michael Trias, Jada Padilla, Hung Tran, Kathleen Meyer, Richard Surosky, Alex Michael Ward
المصدر: Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101228- (2024)
مصطلحات موضوعية: AAV, baculovirus, Sf9 cells, capsid engineering, gene therapy, Genetics, QH426-470, Cytology, QH573-671
وصف الملف: electronic resource
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2
المؤلفون: Yasaman Ataei, Larry Park, D. James Surmeier, B. Joseph Vu, Seung Kwak, Richard T. Surosky, Anand Narayanan, David A. Shivak, Josee Laganiere, Christer Halldin, Andrea Varrone, Matthew C. Mendel, Karsten Tillack, Lei Zhang, Bryan Zeitler, Dmitry Guschin, Lexi Kopan, Sarah J. Hinkley, Kimberly Marlen, Jocelynn R. Pearl, Qi Yu, Taneli Heikkinen, Annette Gärtner, Yalda Sedaghat, Christina Thiede, Miklós Tóth, Jennifer M. Cherone, David Paschon, Jyothisri Kondapalli, Andrea E. Kudwa, Ladislav Mrzljak, Rainier Amora, Kimmo Lehtimäki, Edward J. Rebar, Lenke Tari, Ignacio Munoz-Sanjuan, Jeffrey C. Miller, Sylvie Ramboz, Marie Svedberg, Steven Froelich, Irina Ankoudinova, Philip D. Gregory, Stephen Lam, Michelle Day, Jonathan Bard, Hoang Oanh B. Nguyen, Fyodor D. Urnov, Davis Li, Jenny Haggkvist, H. Steve Zhang, Guijuan Qiao
المصدر: Nature Medicine. 25:1131-1142
مصطلحات موضوعية: 0301 basic medicine, Zinc finger, congenital, hereditary, and neonatal diseases and abnormalities, Mutant, General Medicine, Biology, medicine.disease, General Biochemistry, Genetics and Molecular Biology, nervous system diseases, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Huntington's disease, Transcription (biology), 030220 oncology & carcinogenesis, mental disorders, medicine, Gene silencing, Allele, Gene, Transcription factor
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3Persistent repression of tau in the brain using engineered zinc finger protein transcription factors
المؤلفون: Susanne Wegmann, Bradley T. Hyman, Annemarie Ledeboer, Jeffrey C. Miller, Marta Perez-Rando, Kimberly Marlen, Richard T. Surosky, Bryan Zeitler, Caitlin Commins, Alison Chase, Michael C. Holmes, Sarah J. Hinkley, Alicia Goodwin, Riley N. Bannon, Lei Zhang, Brigit E. Riley, Hoang-Oanh B. Nguyen, Sarah L. DeVos, Edward J. Rebar, Ashley B. Robbins, Stephen Lam, Rainier Amora, Irina Ankoudinova, Qi Yu, Amy M. Pooler, Hung Tran, Nicholas A. Scarlott, Bianca T. Corjuc, Danny MacKenzie, Fyodor D. Urnov, H. Steve Zhang, Lisa Diez, Rachel E. Bennett
المصدر: Science advances 7(12), eabe1611-(2021). doi:10.1126/sciadv.abe1611
Science Advancesمصطلحات موضوعية: Endogeny, Plaque, Amyloid, genetics [Alzheimer Disease], genetics [Dependovirus], Transduction (genetics), pathology [Alzheimer Disease], Mice, 0302 clinical medicine, Research Methods, metabolism [Transcription Factors], genetics [Zinc Fingers], Research Articles, Zinc finger, 0303 health sciences, Gene knockdown, Multidisciplinary, Chemistry, Brain, SciAdv r-articles, Zinc Fingers, Human brain, Dependovirus, genetics [Transcription Factors], Cell biology, medicine.anatomical_structure, ddc:500, Research Article, metabolism [Amyloid beta-Peptides], tau Proteins, 03 medical and health sciences, Alzheimer Disease, mental disorders, medicine, Animals, pathology [Plaque, Amyloid], Transcription factor, 030304 developmental biology, Messenger RNA, Amyloid beta-Peptides, therapy [Alzheimer Disease], Neurotoxicity, medicine.disease, metabolism [tau Proteins], Disease Models, Animal, genetics [tau Proteins], metabolism [Brain], metabolism [Dependovirus], 030217 neurology & neurosurgery, Transcription Factors, Neuroscience
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1e249560ae8a0539e415f467dba78e
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4دورية أكاديمية
المؤلفون: David W Colby, Rachel Wain, Ilia V Baskakov, Giuseppe Legname, Christina G Palmer, Hoang-Oanh B Nguyen, Azucena Lemus, Fred E Cohen, Stephen J DeArmond, Stanley B Prusiner
المصدر: PLoS Pathogens, Vol 6, Iss 1, p e1000736 (2010)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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5
المؤلفون: Bryan, Zeitler, Steven, Froelich, Kimberly, Marlen, David A, Shivak, Qi, Yu, Davis, Li, Jocelynn R, Pearl, Jeffrey C, Miller, Lei, Zhang, David E, Paschon, Sarah J, Hinkley, Irina, Ankoudinova, Stephen, Lam, Dmitry, Guschin, Lexi, Kopan, Jennifer M, Cherone, Hoang-Oanh B, Nguyen, Guijuan, Qiao, Yasaman, Ataei, Matthew C, Mendel, Rainier, Amora, Richard, Surosky, Josee, Laganiere, B Joseph, Vu, Anand, Narayanan, Yalda, Sedaghat, Karsten, Tillack, Christina, Thiede, Annette, Gärtner, Seung, Kwak, Jonathan, Bard, Ladislav, Mrzljak, Larry, Park, Taneli, Heikkinen, Kimmo K, Lehtimäki, Marie M, Svedberg, Jenny, Häggkvist, Lenke, Tari, Miklós, Tóth, Andrea, Varrone, Christer, Halldin, Andrea E, Kudwa, Sylvie, Ramboz, Michelle, Day, Jyothisri, Kondapalli, D James, Surmeier, Fyodor D, Urnov, Philip D, Gregory, Edward J, Rebar, Ignacio, Muñoz-Sanjuán, H Steve, Zhang
المصدر: Nature medicine. 25(7)
مصطلحات موضوعية: Male, Huntingtin Protein, Transcription, Genetic, Zinc Fingers, Neuroprotection, Mice, Inbred C57BL, Disease Models, Animal, Mice, Huntington Disease, Trinucleotide Repeats, Mutation, Mice, Inbred CBA, Animals, Humans, Female, Alleles, Cells, Cultured
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6
المؤلفون: Giuseppe Legname, Stephen J. DeArmond, Holger Wille, Hoang-Oanh B. Nguyen, Joel C. Watts, Azucena Lemus, Joshua Sussman, Kurt Giles, Jan Stöhr, Abby Oehler, Stanley B. Prusiner
المصدر: Proceedings of the National Academy of Sciences. 108:21223-21228
مصطلحات موضوعية: Genetically modified mouse, Amyloid, Protein Folding, Disease onset, Glycosylphosphatidylinositols, animal diseases, Blotting, Western, Mice, Transgenic, Biology, Mice, neurodegenerative disease, Microscopy, Electron, Transmission, Animals, Gerstmann-Straussler-Scheinker Disease, PrPC Proteins, protein misfolding, amyloidosis, Multidisciplinary, proteinopathies, Histological Techniques, Disease progression, Biological Sciences, Molecular biology, nervous system diseases, Disease Models, Animal, Amyloid deposition, Epitope mapping, Electrophoresis, Polyacrylamide Gel, Protein folding, Epitope Mapping, Glycosylphosphatidyl inositol
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47a2950cb664478ff6938a7cc1b681d
https://doi.org/10.1073/pnas.1117827108 -
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المؤلفون: Joel C. Watts, Sina Ghaemmaghami, Stephen J. DeArmond, Hoang-Oanh B. Nguyen, Shigenari Hayashi, Stanley B. Prusiner
المصدر: Journal of Molecular Biology. 413:527-542
مصطلحات موضوعية: Male, Amyloid, Prions, Protein Conformation, Blotting, Western, Population, Mice, Transgenic, Biology, Mice, Neuroblastoma, Protein structure, Structural Biology, Endopeptidases, Tumor Cells, Cultured, Animals, Selection, Genetic, education, Molecular Biology, education.field_of_study, Molecular mass, Strain (chemistry), Brain, Fungal prion, Transformation (genetics), Biochemistry, Nucleic acid, Female
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المؤلفون: Hoang-Oanh B. Nguyen, Frederick Cohen, Stephen J. DeArmond, David Peretz, Giuseppe Legname, Stanley B. Prusiner
المصدر: Proceedings of the National Academy of Sciences. 103:19105-19110
مصطلحات موضوعية: Genetics, Multidisciplinary, Prions, Protein Conformation, animal diseases, Biological Sciences, Biology, Phenotype, nervous system diseases, Prion Diseases, Incubation period, Survival Rate, Mice, chemistry.chemical_compound, Linear relationship, Protein structure, chemistry, Biochemistry, Animals, Prion protein, Guanidine, Incubation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9976df9d9aecacbdc6315d0fc3ac8be
https://doi.org/10.1073/pnas.0608970103 -
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المؤلفون: Stephen J. DeArmond, David Peretz, Stanley B. Prusiner, Michael R. Scott, Hoang-Oanh B. Nguyen
المصدر: Scott, Michael R; Peretz, David; Nguyen, Hoang-Oanh B; Dearmond, Stephen J; & Prusiner, Stanley B. (2005). Transmission barriers for bovine ovine, and human prions in transgenic mice. Journal of Virology, 79(9), 5259-5271. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6xv0v7kk
مصطلحات موضوعية: Genetically modified mouse, PrPSc Proteins, Prions, Ratón, animal diseases, Transgene, Bovine spongiform encephalopathy, Immunology, Mice, Transgenic, Scrapie, Biology, Microbiology, Creutzfeldt-Jakob Syndrome, Mice, Species Specificity, Virology, mental disorders, medicine, Animals, Humans, Sheep, Brain, medicine.disease, nervous system diseases, Encephalopathy, Bovine Spongiform, Disease Models, Animal, Insect Science, Pathogenesis and Immunity, Cattle, Disease Susceptibility, Conformational stability
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8d977395e010c093a91e39e507d2aa
https://doi.org/10.1128/jvi.79.9.5259-5271.2005 -
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المؤلفون: James W. Ironside, Patrick Tremblay, Michael R. Scott, Stephen J. DeArmond, Robert G. Will, Stanley B. Prusiner, Hoang-Oanh B. Nguyen
المصدر: Proceedings of the National Academy of Sciences. 96:15137-15142
مصطلحات موضوعية: Risk, PrPSc Proteins, Prions, animal diseases, Transgene, Bovine spongiform encephalopathy, Mice, Transgenic, Scrapie, Neuropathology, Biology, Creutzfeldt-Jakob Syndrome, Mice, Species Specificity, mental disorders, medicine, Animals, Humans, Tissue Distribution, Multidisciplinary, Transmission (medicine), Neurodegeneration, Brain, Biological Sciences, medicine.disease, Virology, nervous system diseases, Encephalopathy, Bovine Spongiform, Cattle
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a3d558f0bcbfbc382143824f0ff927
https://doi.org/10.1073/pnas.96.26.15137