المؤلفون: Hochstrasser, ML, Taylor, DW, Kornfeld, JE, Nogales, E, Doudna, JA

المصدر: Molecular cell, vol 63, iss 5
Hochstrasser, ML; Taylor, DW; Kornfeld, JE; Nogales, E; & Doudna, JA. (2016). DNA Targeting by a Minimal CRISPR RNA-Guided Cascade. Molecular Cell, 63(5), 840-851. doi: 10.1016/j.molcel.2016.07.027. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1871n7mj

مصطلحات موضوعية: Protein Conformation, 1.1 Normal biological development and functioning, Amino Acid Motifs, Gene Expression, Medical and Health Sciences, Substrate Specificity, Bacterial Proteins, Models, Operon, Escherichia coli, Genetics, Protein Interaction Domains and Motifs, Desulfovibrio vulgaris, Gene Editing, Binding Sites, Cryoelectron Microscopy, alpha-Helical, Bacterial, Molecular, DNA, Biological Sciences, Endonucleases, Recombinant Proteins, Kinetics, Emerging Infectious Diseases, Generic Health Relevance, RNA, Nucleic Acid Conformation, CRISPR-Cas Systems, Guide, Cloning, Protein Binding, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3a5a630b7fb044b99cdc39b1687d7378
https://escholarship.org/uc/item/1871n7mj

المؤلفون: Hochstrasser ML; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA. megan.hochstrasser@berkeley.edu., Nuñez JK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA. jamesnunez@berkeley.edu.

المصدر: Nature microbiology [Nat Microbiol] 2021 Dec; Vol. 6 (12), pp. 1481-1482.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Caspases*/genetics , Clustered Regularly Interspaced Short Palindromic Repeats*/genetics, CRISPR-Cas Systems ; Gene Editing

المؤلفون: Ehrenberg AJ; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Moehle EA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Brook CE; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Doudna Cate AH; University of California, Berkeley, California, United States of America., Witkowsky LB; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Sachdeva R; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hirsh A; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Barry K; Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America., Hamilton JR; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Lin-Shiao E; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., McDevitt S; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Valentin-Alvarado L; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Letourneau KN; University of California, Berkeley, California, United States of America., Hunter L; University of California, Berkeley, California, United States of America., Keller A; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Pestal K; University of California, Berkeley, California, United States of America., Frankino PA; University of California, Berkeley, California, United States of America., Murley A; University of California, Berkeley, California, United States of America., Nandakumar D; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Stahl EC; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Tsuchida CA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Gildea HK; University of California, Berkeley, California, United States of America., Murdock AG; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hochstrasser ML; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., O'Brien E; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Ciling A; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Tsitsiklis A; University of California, Berkeley, California, United States of America., Worden K; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Dugast-Darzacq C; University of California, Berkeley, California, United States of America., Hays SG; University of California, Berkeley, California, United States of America., Barber CC; University of California, Berkeley, California, United States of America., McGarrigle R; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Lam EK; University of California, Berkeley, California, United States of America., Ensminger DC; University of California, Berkeley, California, United States of America., Bardet L; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Sherry C; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Harte A; University of California, Berkeley, California, United States of America.; University Health Services, University of California, Berkeley, California, United States of America., Nicolette G; University of California, Berkeley, California, United States of America.; University Health Services, University of California, Berkeley, California, United States of America., Giannikopoulos P; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hockemeyer D; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America.; Chan Zuckerberg Biohub, San Francisco, California, United States of America., Petersen M; University of California, Berkeley, California, United States of America., Urnov FD; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Ringeisen BR; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Boots M; University of California, Berkeley, California, United States of America., Doudna JA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, California, United States of America.

مؤلفون مشاركون: IGI SARS-CoV-2 Testing Consortium

المصدر: PloS one [PLoS One] 2021 May 26; Vol. 16 (5), pp. e0251296. Date of Electronic Publication: 2021 May 26 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Program Evaluation*, COVID-19/*diagnosis , Saliva/*virology, Adult ; Aged ; COVID-19/epidemiology ; COVID-19/virology ; COVID-19 Testing/methods ; Female ; Humans ; Male ; Middle Aged ; RNA, Viral/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Social Norms ; Surveys and Questionnaires ; Universities ; Young Adult

المؤلفون: Foss DV; Innovative Genomics Institute, University of California, Berkeley, Berkeley, California.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California., Hochstrasser ML; Innovative Genomics Institute, University of California, Berkeley, Berkeley, California., Wilson RC; Innovative Genomics Institute, University of California, Berkeley, Berkeley, California.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California.

المصدر: Transfusion [Transfusion] 2019 Apr; Vol. 59 (4), pp. 1389-1399. Date of Electronic Publication: 2019 Jan 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: American Association Of Blood Banks Country of Publication: United States NLM ID: 0417360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-2995 (Electronic) Linking ISSN: 00411132 NLM ISO Abbreviation: Transfusion Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems* , Gene Editing*, Neoplasms/*diagnosis , Neoplasms/*genetics, Animals ; Humans

المؤلفون: Farboud B; Department of Molecular Cell Biology, University of California, Berkeley; Howard Hughes Medical Institute, University of California, Berkeley., Jarvis E; Department of Molecular Cell Biology, University of California, Berkeley., Roth TL; Innovative Genomics Institute, University of California, Berkeley; Biomedical Sciences Graduate Program, University of California, San Francisco; Department of Microbiology and Immunology, University of California, San Francisco; Diabetes Center, University of California, San Francisco., Shin J; Department of Molecular Cell Biology, University of California, Berkeley; Innovative Genomics Institute, University of California, Berkeley., Corn JE; Department of Molecular Cell Biology, University of California, Berkeley; Innovative Genomics Institute, University of California, Berkeley., Marson A; Innovative Genomics Institute, University of California, Berkeley; Department of Microbiology and Immunology, University of California, San Francisco; Diabetes Center, University of California, San Francisco; Chan Zuckerberg Biohub; Department of Medicine, University of California, San Francisco; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco., Meyer BJ; Department of Molecular Cell Biology, University of California, Berkeley; Howard Hughes Medical Institute, University of California, Berkeley., Patel NH; Department of Molecular Cell Biology, University of California, Berkeley; Department of Integrative Biology, University of California, Berkeley., Hochstrasser ML; Innovative Genomics Institute, University of California, Berkeley; megan.hochstrasser@berkeley.edu.

المصدر: Journal of visualized experiments : JoVE [J Vis Exp] 2018 May 25 (135). Date of Electronic Publication: 2018 May 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Video-Audio Media

بيانات الدورية: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems/*genetics , Gene Editing/*methods , Ribonucleoproteins/*genetics, Humans ; Ribonucleoproteins/metabolism

المؤلفون: Hochstrasser ML; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Taylor DW; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: dtaylor@utexas.edu., Kornfeld JE; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA., Nogales E; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics and Integrative Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Doudna JA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics and Integrative Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: doudna@berkeley.edu.

المصدر: Molecular cell [Mol Cell] 2016 Sep 01; Vol. 63 (5), pp. 840-51.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*, Bacterial Proteins/*genetics , DNA/*genetics , Desulfovibrio vulgaris/*genetics , Endonucleases/*genetics , RNA, Bacterial/*genetics , RNA, Guide, CRISPR-Cas Systems/*genetics, Amino Acid Motifs ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Binding Sites ; Cloning, Molecular ; Cryoelectron Microscopy ; DNA/chemistry ; DNA/metabolism ; Desulfovibrio vulgaris/metabolism ; Endonucleases/chemistry ; Endonucleases/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Editing ; Gene Expression ; Kinetics ; Models, Molecular ; Nucleic Acid Conformation ; Operon ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Interaction Domains and Motifs ; RNA, Bacterial/chemistry ; RNA, Bacterial/metabolism ; RNA, Guide, CRISPR-Cas Systems/chemistry ; RNA, Guide, CRISPR-Cas Systems/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Substrate Specificity

المؤلفون: Klaips CL, Hochstrasser ML, Langlois CR, Serio TR

المصدر: ELife [Elife] 2015 Jan 28; Vol. 4, pp. e06494. Date of Electronic Publication: 2015 Jan 28.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: PubMed not MEDLINE

المؤلفون: Hochstrasser ML; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Doudna JA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720, USA; Department of Chemistry, University of California, Berkeley, CA 94720, USA; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: doudna@berkeley.edu.

المصدر: Trends in biochemical sciences [Trends Biochem Sci] 2015 Jan; Vol. 40 (1), pp. 58-66. Date of Electronic Publication: 2014 Nov 18.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Trends Journals Country of Publication: England NLM ID: 7610674 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0968-0004 (Print) Linking ISSN: 09680004 NLM ISO Abbreviation: Trends Biochem Sci Subsets: MEDLINE

مواضيع طبية MeSH: Structure-Activity Relationship*, CRISPR-Associated Proteins/*chemistry , CRISPR-Cas Systems/*genetics , Endoribonucleases/*chemistry, Bacteria/genetics ; Bacteria/immunology ; CRISPR-Associated Proteins/genetics ; CRISPR-Associated Proteins/metabolism ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Protein Conformation ; Protein Folding ; RNA/chemistry ; RNA/genetics ; RNA Interference ; Substrate Specificity

المؤلفون: Klaips CL; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, United States., Hochstrasser ML; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, United States., Langlois CR; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, United States., Serio TR; Department of Molecular and Cellular Biology, University of Arizona, Tucson, United States.

المصدر: ELife [Elife] 2014 Dec 09; Vol. 3. Date of Electronic Publication: 2014 Dec 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Protein Folding* , Quality Control*, Prions/*physiology, Heat-Shock Proteins/metabolism ; Hot Temperature ; Prions/chemistry ; Stress, Physiological

المؤلفون: Hochstrasser ML; Department of Molecular and Cell Biology, Howard Hughes Medical Institute, California Institute for Quantitative Biosciences, and Department of Chemistry, University of California, Berkeley, CA 94720., Taylor DW, Bhat P, Guegler CK, Sternberg SH, Nogales E, Doudna JA

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 May 06; Vol. 111 (18), pp. 6618-23. Date of Electronic Publication: 2014 Apr 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Associated Proteins/*metabolism , DNA Helicases/*metabolism , Escherichia coli Proteins/*metabolism, Base Sequence ; Binding Sites/genetics ; CRISPR-Associated Proteins/chemistry ; CRISPR-Associated Proteins/genetics ; Cryoelectron Microscopy ; DNA Helicases/chemistry ; DNA Helicases/genetics ; Escherichia coli K12/genetics ; Escherichia coli K12/metabolism ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/genetics ; Imaging, Three-Dimensional ; Macromolecular Substances/chemistry ; Macromolecular Substances/ultrastructure ; Models, Molecular ; Molecular Sequence Data ; Nucleic Acid Conformation ; Protein Conformation ; Protein Subunits ; RNA Interference ; RNA, Bacterial/chemistry ; RNA, Bacterial/genetics ; RNA, Bacterial/metabolism