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المؤلفون: Aronov, Am, CHRISTOPHE VERLINDE, Hol, Wg, Gelb, Mh

المصدر: ResearcherID

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3433adcc9c5b4adc675d78c8858df21f
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=BCI&KeyUT=BCI:BCI199799497133&KeyUID=BCI:BCI199799497133

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المؤلفون: Devine WG; Department of Chemistry & Chemical Biology, Northeastern University 360 Huntington Avenue, Boston, Massachusetts, United States., Diaz-Gonzalez R; Instituto de Parasitologia y Biomedicina 'Lopez-Neyra', Consejo Superior de Investigaciones Cientificas (CSIC) , Granada 18100, Spain., Ceballos-Perez G; Instituto de Parasitologia y Biomedicina 'Lopez-Neyra', Consejo Superior de Investigaciones Cientificas (CSIC) , Granada 18100, Spain., Rojas D; Instituto de Parasitologia y Biomedicina 'Lopez-Neyra', Consejo Superior de Investigaciones Cientificas (CSIC) , Granada 18100, Spain., Satoh T; Department of Chemistry & Chemical Biology, Northeastern University 360 Huntington Avenue, Boston, Massachusetts, United States., Tear W; Department of Chemistry & Chemical Biology, Northeastern University 360 Huntington Avenue, Boston, Massachusetts, United States., Ranade RM, Barros-Álvarez X; Laboratorio de Enzimología de Parásitos, Facultad de Ciencias, Universidad de los Andes , Mérida, Venezuela., Hol WG, Buckner FS, Navarro M; Instituto de Parasitologia y Biomedicina 'Lopez-Neyra', Consejo Superior de Investigaciones Cientificas (CSIC) , Granada 18100, Spain., Pollastri MP; Department of Chemistry & Chemical Biology, Northeastern University 360 Huntington Avenue, Boston, Massachusetts, United States.

المصدر: ACS infectious diseases [ACS Infect Dis] 2017 Mar 10; Vol. 3 (3), pp. 225-236. Date of Electronic Publication: 2017 Feb 08.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Small Molecule Libraries/*pharmacology , Trypanocidal Agents/*pharmacology , Trypanosomiasis, African/*drug therapy, Animals ; Crystallography, X-Ray ; Disease Models, Animal ; Humans ; Mice ; Neglected Diseases ; Small Molecule Libraries/chemistry ; Structure-Activity Relationship ; Trypanocidal Agents/chemistry ; Trypanosoma brucei brucei/drug effects

المؤلفون: Rule CS; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan., Patrick M; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan., Camberg JL; Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Rockville, Maryland., Maricic N; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan., Hol WG; Department of Biochemistry, Biomolecular Structure Center, University of Washington, Seattle, Washington., Sandkvist M; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan. mariasan@umich.edu.

المصدر: MicrobiologyOpen [Microbiologyopen] 2016 Oct; Vol. 5 (5), pp. 870-882. Date of Electronic Publication: 2016 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101588314 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-8827 (Electronic) Linking ISSN: 20458827 NLM ISO Abbreviation: Microbiologyopen Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*metabolism , Cholera Toxin/*metabolism , Membrane Proteins/*metabolism , Membrane Transport Proteins/*metabolism , Type II Secretion Systems/*metabolism , Vibrio cholerae/*metabolism , Zinc/*metabolism, Adenosine Triphosphatases/metabolism ; Adenosine Triphosphate/metabolism ; Bacterial Proteins/genetics ; Biological Transport/physiology ; Fimbriae Proteins/metabolism ; Membrane Proteins/genetics ; Protein Structure, Tertiary ; Pseudomonas aeruginosa/enzymology ; Pseudomonas aeruginosa/metabolism ; Type II Secretion Systems/genetics ; Vibrio cholerae/enzymology

المؤلفون: Vidadala RS; Department of Chemistry, University of Washington , Seattle, Washington 98195, United States., Rivas KL; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-Emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Ojo KK; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-Emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Hulverson MA; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-Emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Zambriski JA; Paul G. Allen School for Global Animal Health, College of Veterinary Medicine, Washington State University , Pullman, Washington 99164, United States., Bruzual I; Portland VA Medical Center , Portland, Oregon 97239, United States., Schultz TL; Department of Microbiology and Immunology, University of Michigan Medical School , Ann Arbor, Michigan 48109, United States., Huang W; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Zhang Z; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Scheele S; Center for Infectious Disease Research (formerly Seattle Biomedical Research Institute), Seattle, Washington 98109, United States., DeRocher AE; Center for Infectious Disease Research (formerly Seattle Biomedical Research Institute), Seattle, Washington 98109, United States., Choi R; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-Emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Barrett LK; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-Emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Siddaramaiah LK; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Hol WG; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Fan E; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Merritt EA; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Parsons M; Center for Infectious Disease Research (formerly Seattle Biomedical Research Institute), Seattle, Washington 98109, United States.; Department of Global Health, University of Washington , Seattle, Washington 98195, United States., Freiberg G; AbbVie , North Chicago, Illinois 60064, United States., Marsh K; AbbVie , North Chicago, Illinois 60064, United States., Kempf DJ; AbbVie , North Chicago, Illinois 60064, United States., Carruthers VB; Department of Microbiology and Immunology, University of Michigan Medical School , Ann Arbor, Michigan 48109, United States., Isoherranen N; Department of Pharmaceutics, University of Washington , Seattle, Washington 98195, United States., Doggett JS; Portland VA Medical Center , Portland, Oregon 97239, United States., Van Voorhis WC; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-Emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States.; Department of Global Health, University of Washington , Seattle, Washington 98195, United States., Maly DJ; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States.; Department of Chemistry, University of Washington , Seattle, Washington 98195, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2016 Jul 14; Vol. 59 (13), pp. 6531-46. Date of Electronic Publication: 2016 Jul 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Antiprotozoal Agents/*pharmacology , Central Nervous System/*drug effects , Ether-A-Go-Go Potassium Channels/*antagonists & inhibitors , Protein Kinase Inhibitors/*pharmacology , Protein Kinases/*metabolism , Toxoplasma/*drug effects , Toxoplasmosis/*drug therapy, Administration, Oral ; Animals ; Antiprotozoal Agents/administration & dosage ; Antiprotozoal Agents/chemistry ; Disease Models, Animal ; Dogs ; Dose-Response Relationship, Drug ; Ether-A-Go-Go Potassium Channels/metabolism ; Female ; Haplorhini ; Mice ; Mice, Inbred BALB C ; Molecular Structure ; Parasitic Sensitivity Tests ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/chemistry ; Rats ; Rats, Sprague-Dawley ; Structure-Activity Relationship ; Toxoplasma/enzymology ; Toxoplasmosis/metabolism

المؤلفون: Zhang Z; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States., Koh CY; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States., Ranade RM; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , 750 Republican Street, Seattle, Washington 98109, United States., Shibata S; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States., Gillespie JR; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , 750 Republican Street, Seattle, Washington 98109, United States., Hulverson MA; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , 750 Republican Street, Seattle, Washington 98109, United States., Huang W; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States., Nguyen J; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States., Pendem N; Department of Chemistry, Bagley Hall, University of Washington , Seattle, Washington 98195, United States., Gelb MH; Department of Chemistry, Bagley Hall, University of Washington , Seattle, Washington 98195, United States., Verlinde CL; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States., Hol WG; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States., Buckner FS; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , 750 Republican Street, Seattle, Washington 98109, United States., Fan E; Department of Biochemistry, University of Washington , 1705 N.E. Pacific Street, Seattle, Washington 98195, United States.

المصدر: ACS infectious diseases [ACS Infect Dis] 2016 Jun 10; Vol. 2 (6), pp. 399-404. Date of Electronic Publication: 2016 Apr 11.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Inhibitors/*chemistry , Methionine-tRNA Ligase/*antagonists & inhibitors , Protozoan Proteins/*antagonists & inhibitors , Trypanocidal Agents/*chemistry , Trypanosoma brucei brucei/*drug effects , Trypanosomiasis, African/*parasitology, Animals ; Enzyme Inhibitors/pharmacology ; Female ; Humans ; Methionine-tRNA Ligase/genetics ; Methionine-tRNA Ligase/metabolism ; Mice ; Molecular Structure ; Protozoan Proteins/genetics ; Protozoan Proteins/metabolism ; Pyridines/chemistry ; Trypanocidal Agents/pharmacology ; Trypanosoma brucei brucei/enzymology ; Trypanosoma brucei brucei/genetics

المؤلفون: Ranade RM; Department of Medicine, University of Washington, Seattle, Washington, USA., Zhang Z; Department of Biochemistry, University of Washington, Seattle, Washington, USA., Gillespie JR; Department of Medicine, University of Washington, Seattle, Washington, USA., Shibata S; Department of Biochemistry, University of Washington, Seattle, Washington, USA., Verlinde CL; Department of Biochemistry, University of Washington, Seattle, Washington, USA., Hol WG; Department of Biochemistry, University of Washington, Seattle, Washington, USA., Fan E; Department of Biochemistry, University of Washington, Seattle, Washington, USA., Buckner FS; Department of Medicine, University of Washington, Seattle, Washington, USA fbuckner@uw.edu.

المصدر: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Nov; Vol. 59 (11), pp. 7128-31. Date of Electronic Publication: 2015 Aug 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

مواضيع طبية MeSH: Antiprotozoal Agents/*pharmacology , Giardia lamblia/*drug effects , Methionine-tRNA Ligase/*antagonists & inhibitors , Trophozoites/*drug effects, Giardia lamblia/enzymology ; Metronidazole/pharmacology ; Trophozoites/enzymology

المؤلفون: Huang W; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Ojo KK; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Zhang Z; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Rivas K; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Vidadala RS; Department of Chemistry, University of Washington , Seattle, Washington 98195, United States., Scheele S; Center for Infectious Disease Research (formerly Seattle Biomedical Research Institute), Seattle, Washington 98109, United States., DeRocher AE; Center for Infectious Disease Research (formerly Seattle Biomedical Research Institute), Seattle, Washington 98109, United States., Choi R; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Hulverson MA; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Barrett LK; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States., Bruzual I; Portland VA Medical Center , Portland, Oregon 97239, United States., Siddaramaiah LK; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Kerchner KM; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Kurnick MD; AbbVie , N. Chicago, Illinois 60064, United States., Freiberg GM; AbbVie , N. Chicago, Illinois 60064, United States., Kempf D; AbbVie , N. Chicago, Illinois 60064, United States., Hol WG; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Merritt EA; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States., Neckermann G; PATH , San Francisco, California 94102, United States., de Hostos EL; PATH , San Francisco, California 94102, United States., Isoherranen N; Department of Pharmaceutics, University of Washington , Seattle, Washington 98195, United States., Maly DJ; Department of Chemistry, University of Washington , Seattle, Washington 98195, United States., Parsons M; Center for Infectious Disease Research (formerly Seattle Biomedical Research Institute), Seattle, Washington 98109, United States ; Department of Global Health, University of Washington , Seattle, Washington 98195, United States., Doggett JS; Portland VA Medical Center , Portland, Oregon 97239, United States., Van Voorhis WC; Department of Medicine, Division of Allergy and Infectious Diseases, and the Center for Emerging and Re-emerging Infectious Diseases (CERID), University of Washington , Seattle, Washington 98109, United States ; Department of Global Health, University of Washington , Seattle, Washington 98195, United States., Fan E; Department of Biochemistry, University of Washington , Seattle, Washington 98195, United States.

المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2015 Oct 22; Vol. 6 (12), pp. 1184-1189. Date of Electronic Publication: 2015 Oct 22 (Print Publication: 2015).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

المؤلفون: Koh CY; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Siddaramaiah LK; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Ranade RM; Department of Medicine, University of Washington, Seattle, WA 98195, USA., Nguyen J; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Jian T; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Zhang Z; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Gillespie JR; Department of Medicine, University of Washington, Seattle, WA 98195, USA., Buckner FS; Department of Medicine, University of Washington, Seattle, WA 98195, USA., Verlinde CL; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Fan E; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Hol WG; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.

المصدر: Acta crystallographica. Section D, Biological crystallography [Acta Crystallogr D Biol Crystallogr] 2015 Aug; Vol. 71 (Pt 8), pp. 1684-98. Date of Electronic Publication: 2015 Jul 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9305878 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0047 (Electronic) Linking ISSN: 09074449 NLM ISO Abbreviation: Acta Crystallogr D Biol Crystallogr Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Inhibitors/*chemistry , Histidine-tRNA Ligase/*antagonists & inhibitors , Histidine-tRNA Ligase/*chemistry , Small Molecule Libraries/*chemistry , Trypanosoma cruzi/*enzymology, Binding Sites ; Chagas Disease/drug therapy ; Chagas Disease/microbiology ; Drug Discovery ; Enzyme Inhibitors/pharmacology ; Histidine-tRNA Ligase/metabolism ; Humans ; Models, Molecular ; Small Molecule Libraries/pharmacology ; Trypanosoma cruzi/chemistry ; Trypanosoma cruzi/drug effects ; Trypanosoma cruzi/metabolism