المؤلفون: Hay J; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.; Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, 21 Shelley Road, Glasgow G12 0ZD, UK., Tarafdar A; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Holroyd AK; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Moka HA; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Dunn KM; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.; Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, 21 Shelley Road, Glasgow G12 0ZD, UK., Alshayeb A; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK., Lloyd BH; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK., Cassels J; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.; Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, 21 Shelley Road, Glasgow G12 0ZD, UK., Malik N; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Khan AF; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Sou I; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Lees J; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.; Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, 21 Shelley Road, Glasgow G12 0ZD, UK., Almuhanna HNB; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.; Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, 21 Shelley Road, Glasgow G12 0ZD, UK., Kalakonda N; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK., Slupsky JR; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK., Michie AM; School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.; Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, 21 Shelley Road, Glasgow G12 0ZD, UK.

المصدر: Cancers [Cancers (Basel)] 2022 Dec 06; Vol. 14 (23). Date of Electronic Publication: 2022 Dec 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Cosimo E; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Tarafdar A; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Moles MW; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Holroyd AK; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Malik N; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Catherwood MA; Department of Haematology, Belfast City Hospital, Belfast, United Kingdom., Hay J; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Dunn KM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Macdonald AM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Guichard SM; Forma Therapeutics, Watertown, Massachusetts., O'Rourke D; Department of Histopathology, Belfast City Hospital, Belfast, United Kingdom., Leach MT; Department of Haematology, Gartnavel General Hospital, Glasgow, United Kingdom., Sansom OJ; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Cosulich SC; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, United Kingdom., McCaig AM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Royal Alexandra Hospital, Paisley, United Kingdom., Michie AM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom. Alison.Michie@glasgow.ac.uk.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 Mar 01; Vol. 25 (5), pp. 1574-1587. Date of Electronic Publication: 2018 Dec 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Forkhead Box Protein O1/*metabolism , Leukemia, Lymphocytic, Chronic, B-Cell/*metabolism , Leukemia, Lymphocytic, Chronic, B-Cell/*mortality , Mechanistic Target of Rapamycin Complex 2/*antagonists & inhibitors , Protein Kinase Inhibitors/*pharmacology , Proto-Oncogene Proteins c-akt/*antagonists & inhibitors , Receptors, Antigen, B-Cell/*metabolism, Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease Models, Animal ; Drug Synergism ; Female ; Forkhead Box Protein O1/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy ; Leukemia, Lymphocytic, Chronic, B-Cell/genetics ; Male ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Mice ; Mice, Transgenic ; Prognosis ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Treatment Outcome ; Xenograft Model Antitumor Assays

المؤلفون: Holroyd AK; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. Electronic address: Ailsa.Holroyd@glasgow.ac.uk., Michie AM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. Electronic address: Alison.Michie@glasgow.ac.uk.

المصدر: Immunology letters [Immunol Lett] 2018 Apr; Vol. 196, pp. 74-79. Date of Electronic Publication: 2018 Feb 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7910006 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0542 (Electronic) Linking ISSN: 01652478 NLM ISO Abbreviation: Immunol Lett Subsets: MEDLINE

مواضيع طبية MeSH: B-Lymphocytes/*immunology , Cell Movement/*immunology , Signal Transduction/*immunology , TOR Serine-Threonine Kinases/*immunology, B-Lymphocytes/drug effects ; B-Lymphocytes/pathology ; Cell Movement/drug effects ; Humans ; Immunosuppressive Agents/pharmacology ; Leukemia, Lymphocytic, Chronic, B-Cell/immunology ; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism ; Models, Immunological ; Morpholines/pharmacology ; Signal Transduction/drug effects ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; TOR Serine-Threonine Kinases/metabolism