المؤلفون: Lawson H; The Institute of Cancer Research, London, UK.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Holt-Martyn JP; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Dembitz V; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.; Department of Physiology and Immunology and Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia., Kabayama Y; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Wang LM; The Institute of Cancer Research, London, UK.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Bellani A; The Institute of Cancer Research, London, UK.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Atwal S; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Saffoon N; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Durko J; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., van de Lagemaat LN; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., De Pace AL; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Tumber A; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Corner T; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Salah E; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Arndt C; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Brewitz L; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Bowen M; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK., Dubusse L; The Institute of Cancer Research, London, UK.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., George D; The Institute of Cancer Research, London, UK.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Allen L; The Institute of Cancer Research, London, UK.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Guitart AV; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.; Université de Bordeaux, Institut National de la Santé et de la Recherche Médicale INSERM U1035, Bordeaux, France., Fung TK; Leukemia and Stem Cell Biology Group, Comprehensive Cancer Centre, King's College London, London, UK.; Department of Haematological Medicine, King's College Hospital, King's College London, London, UK., So CWE; Leukemia and Stem Cell Biology Group, Comprehensive Cancer Centre, King's College London, London, UK.; Department of Haematological Medicine, King's College Hospital, King's College London, London, UK., Schwaller J; University Children's Hospital Basel (UKBB), Department of Biomedicine, University of Basel, Basel, Switzerland., Gallipoli P; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., O'Carroll D; Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, UK. christopher.schofield@chem.ox.ac.uk., Kranc KR; The Institute of Cancer Research, London, UK. kamil.kranc@icr.ac.uk.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. kamil.kranc@icr.ac.uk.

المصدر: Nature cancer [Nat Cancer] 2024 Jun; Vol. 5 (6), pp. 916-937. Date of Electronic Publication: 2024 Apr 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/metabolism , Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism , Hypoxia-Inducible Factor-Proline Dioxygenases*/antagonists & inhibitors , Hypoxia-Inducible Factor-Proline Dioxygenases*/metabolism , Prolyl-Hydroxylase Inhibitors*/pharmacology , Prolyl-Hydroxylase Inhibitors*/therapeutic use , Disease Progression*, Humans ; Animals ; Mice ; Apoptosis/drug effects ; Proto-Oncogene Proteins/metabolism ; Membrane Proteins/metabolism ; Membrane Proteins/genetics ; Cell Line, Tumor ; Sulfonamides/pharmacology ; Sulfonamides/therapeutic use ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Protein Stability/drug effects ; Bridged Bicyclo Compounds, Heterocyclic

المؤلفون: Corner TP; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Teo RZR; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Wu Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Design and Optimization and Department of Chemistry, China Pharmaceutical University Nanjing 211198 China zxj@cpu.edu.cn., Salah E; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Nakashima Y; Institute of Natural Medicine, University of Toyama 2630-Sugitani 930-0194 Toyama Japan., Fiorini G; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Tumber A; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Brasnett A; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Holt-Martyn JP; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Figg WD Jr; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Zhang X; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Design and Optimization and Department of Chemistry, China Pharmaceutical University Nanjing 211198 China zxj@cpu.edu.cn., Brewitz L; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.

المصدر: Chemical science [Chem Sci] 2023 Oct 27; Vol. 14 (43), pp. 12098-12120. Date of Electronic Publication: 2023 Oct 27 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

المؤلفون: Islam MS; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, The Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, 12 Mansfield Road, OX1 3TA, Oxford, UK., Thinnes CC; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, The Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, 12 Mansfield Road, OX1 3TA, Oxford, UK., Holt-Martyn JP; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, The Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, 12 Mansfield Road, OX1 3TA, Oxford, UK., Chowdhury R; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, The Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, 12 Mansfield Road, OX1 3TA, Oxford, UK., McDonough MA; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, The Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, 12 Mansfield Road, OX1 3TA, Oxford, UK., Schofield CJ; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, The Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, 12 Mansfield Road, OX1 3TA, Oxford, UK.

المصدر: ChemMedChem [ChemMedChem] 2022 Jan 05; Vol. 17 (1), pp. e202100398. Date of Electronic Publication: 2021 Nov 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

مواضيع طبية MeSH: Jumonji Domain-Containing Histone Demethylases/*antagonists & inhibitors , Ketoglutaric Acids/*pharmacology , Prolyl-Hydroxylase Inhibitors/*pharmacology, Dose-Response Relationship, Drug ; Humans ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Ketoglutaric Acids/chemistry ; Molecular Structure ; Prolyl-Hydroxylase Inhibitors/chemistry ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Structure-Activity Relationship

المؤلفون: Figg WD Jr; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., McDonough MA; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Chowdhury R; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.; Cardiovascular Research Institute, University of California, San Francisco, 555 Mission Bay Blvd., San Francisco, CA 94158, USA., Nakashima Y; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.; Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan., Zhang Z; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Holt-Martyn JP; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Krajnc A; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Schofield CJ; Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

المصدر: ChemMedChem [ChemMedChem] 2021 Jul 06; Vol. 16 (13), pp. 2082-2088. Date of Electronic Publication: 2021 Apr 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

مواضيع طبية MeSH: Prolyl Hydroxylases/*metabolism , Prolyl-Hydroxylase Inhibitors/*pharmacology , Pyrazoles/*pharmacology , Triazoles/*pharmacology, Dose-Response Relationship, Drug ; Humans ; Models, Molecular ; Molecular Structure ; Prolyl-Hydroxylase Inhibitors/chemistry ; Pyrazoles/chemistry ; Structure-Activity Relationship ; Triazoles/chemistry

المؤلفون: Holt-Martyn JP; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Chowdhury R; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Tumber A; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Yeh TL; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Abboud MI; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Lippl K; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Lohans CT; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Langley GW; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Figg W Jr; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., McDonough MA; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK., Pugh CW; NDM Research Building, University of Oxford, Oxford, OX3 7FZ, UK., Ratcliffe PJ; NDM Research Building, University of Oxford, Oxford, OX3 7FZ, UK.; The Francis Crick Institute, London, NW1 1AT, UK., Schofield CJ; Department of Chemistry, University of Oxford Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK.

المصدر: ChemMedChem [ChemMedChem] 2020 Feb 05; Vol. 15 (3), pp. 270-273. Date of Electronic Publication: 2019 Dec 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

مواضيع طبية MeSH: Hypoxia-Inducible Factor-Proline Dioxygenases/*antagonists & inhibitors , Prolyl-Hydroxylase Inhibitors/*pharmacology , Pyrimidinones/*pharmacology, Crystallography, X-Ray ; Dose-Response Relationship, Drug ; Humans ; Hypoxia-Inducible Factor-Proline Dioxygenases/metabolism ; Models, Molecular ; Molecular Structure ; Prolyl-Hydroxylase Inhibitors/chemistry ; Pyrimidinones/chemistry ; Structure-Activity Relationship

المؤلفون: Holt-Martyn JP; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Tumber A; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Rahman MZ; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Lippl K; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Figg W Jr; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., McDonough MA; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Chowdhury R; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Schofield CJ; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford , OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk.

المصدر: MedChemComm [Medchemcomm] 2019 Mar 01; Vol. 10 (4), pp. 500-504. Date of Electronic Publication: 2019 Mar 01 (Print Publication: 2019).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101531525 Publication Model: eCollection Cited Medium: Internet ISSN: 2040-2511 (Electronic) Linking ISSN: 20402503 NLM ISO Abbreviation: Medchemcomm Subsets: PubMed not MEDLINE

المؤلفون: Yeh TL; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk.; Target Discovery Institute (TDI) , Nuffield Department of Medicine , University of Oxford , NDMRB Roosevelt Drive , Oxford OX3 7FZ , UK., Leissing TM; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk.; Ludwig Institute for Cancer Research , Nuffield Department of Clinical Medicine , University of Oxford , Oxford OX3 7DQ , UK., Abboud MI; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Thinnes CC; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Atasoylu O; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Holt-Martyn JP; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Zhang D; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Tumber A; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk.; Structural Genomics Consortium (SGC) , University of Oxford , Oxford OX3 7DQ , UK., Lippl K; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Lohans CT; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Leung IKH; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Morcrette H; Radcliffe Department of Medicine , Division of Cardiovascular Medicine , BHF Centre of Research Excellence , Wellcome Trust Centre for Human Genetics , Roosevelt Drive , Oxford OX3 7BN , UK., Clifton IJ; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Claridge TDW; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Kawamura A; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk.; Radcliffe Department of Medicine , Division of Cardiovascular Medicine , BHF Centre of Research Excellence , Wellcome Trust Centre for Human Genetics , Roosevelt Drive , Oxford OX3 7BN , UK., Flashman E; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Lu X; Ludwig Institute for Cancer Research , Nuffield Department of Clinical Medicine , University of Oxford , Oxford OX3 7DQ , UK., Ratcliffe PJ; Target Discovery Institute (TDI) , Nuffield Department of Medicine , University of Oxford , NDMRB Roosevelt Drive , Oxford OX3 7FZ , UK.; The Francis Crick Institute , 1 Midland Road , London NW1 1AT , UK., Chowdhury R; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk., Pugh CW; Target Discovery Institute (TDI) , Nuffield Department of Medicine , University of Oxford , NDMRB Roosevelt Drive , Oxford OX3 7FZ , UK., Schofield CJ; Chemistry Research Laboratory , Department of Chemistry , University of Oxford , Oxford OX1 3TA , UK . Email: christopher.schofield@chem.ox.ac.uk.

المصدر: Chemical science [Chem Sci] 2017 Nov 01; Vol. 8 (11), pp. 7651-7668. Date of Electronic Publication: 2017 Sep 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

المؤلفون: Chan MC; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Holt-Martyn JP; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom. Electronic address: christopher.schofield@chem.ox.ac.uk., Ratcliffe PJ; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom. Electronic address: pjr@well.ox.ac.uk.

المصدر: Molecular aspects of medicine [Mol Aspects Med] 2016 Feb-Mar; Vol. 47-48, pp. 54-75. Date of Electronic Publication: 2016 Jan 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 7603128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9452 (Electronic) Linking ISSN: 00982997 NLM ISO Abbreviation: Mol Aspects Med Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems*, Hypoxia/*metabolism , Hypoxia-Inducible Factor 1/*metabolism , Mixed Function Oxygenases/*antagonists & inhibitors, Anemia/drug therapy ; Animals ; Disease Models, Animal ; Erythropoietin/deficiency ; Erythropoietin/metabolism ; Humans ; Hypoxia-Inducible Factor 1/antagonists & inhibitors ; Inflammation/drug therapy ; Ischemia/drug therapy ; Mixed Function Oxygenases/metabolism ; Oxygen/metabolism ; Prolyl-Hydroxylase Inhibitors/pharmacology ; Protein Conformation ; Randomized Controlled Trials as Topic