المؤلفون: Hone AJ; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.; MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah 84148, United States., Santiago U; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, United States., Harvey PJ; Institute for Molecular Bioscience, ARC Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia., Tekarli B; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Gajewiak J; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States., Craik DJ; Institute for Molecular Bioscience, ARC Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia., Camacho CJ; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, United States., McIntosh JM; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.; Department of Psychiatry, University of Utah, Salt Lake City, Utah 84112, United States.; George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah 84148, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jun 13; Vol. 67 (11), pp. 9587-9598. Date of Electronic Publication: 2024 May 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Spike Glycoprotein, Coronavirus*/metabolism , Spike Glycoprotein, Coronavirus*/chemistry , Drug Design* , Receptors, Nicotinic*/metabolism , SARS-CoV-2*/drug effects , Nicotinic Antagonists*/pharmacology , Nicotinic Antagonists*/chemistry , Nicotinic Antagonists*/chemical synthesis, Structure-Activity Relationship ; Humans ; Peptides/pharmacology ; Peptides/chemistry ; Peptides/chemical synthesis ; Animals ; Amino Acid Sequence ; Molecular Dynamics Simulation

المؤلفون: Williams BM; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Steed ND; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Woolley JT; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Moedl AA; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Nelson CA; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Jones GC; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Burris MD; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Arias HR; Department of Pharmacology and Physiology, Oklahoma State University College of Osteopathic Medicine, Tahlequah, Oklahoma 74464, United States., Kim OH; Department of Advanced Toxicology Research, Korea Institute of Toxicology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, Korea., Jang EY; Department of Advanced Toxicology Research, Korea Institute of Toxicology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, Korea., Hone AJ; George E. Wahlen Veterans Affairs Medical Center, and Departments of Psychiatry and Biology, University of Utah, Salt Lake City, Utah 84112, United States., McIntosh JM; George E. Wahlen Veterans Affairs Medical Center, and Departments of Psychiatry and Biology, University of Utah, Salt Lake City, Utah 84112, United States., Yorgason JT; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States., Steffensen SC; Department of Psychology/Neuroscience, Brigham Young University, Provo, Utah 84602, United States.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2024 May 01; Vol. 15 (9), pp. 1738-1754. Date of Electronic Publication: 2024 Apr 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Ibogaine*/*analogs & derivatives, Dopamine*/metabolism , Receptors, Nicotinic*/metabolism , Receptors, Nicotinic*/drug effects , Nicotine*/pharmacology , Ibogaine*/pharmacology , Dopamine Plasma Membrane Transport Proteins*/metabolism , Dopamine Plasma Membrane Transport Proteins*/drug effects, Animals ; Male ; Mice ; Nucleus Accumbens/drug effects ; Nucleus Accumbens/metabolism ; Mice, Inbred C57BL ; Nicotinic Antagonists/pharmacology ; Oocytes/drug effects ; Nicotinic Agonists/pharmacology ; Synaptic Transmission/drug effects ; Synaptic Transmission/physiology ; Self Administration ; Xenopus laevis ; Interneurons/drug effects ; Interneurons/metabolism ; Dose-Response Relationship, Drug ; Motor Activity/drug effects

المؤلفون: Neves JLB; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR-LA), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Urcino C; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Chase K; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Dowell C; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Hone AJ; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; Mental Illness Research Education and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA., Morgenstern D; Departments of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10016, USA., Chua VM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Ramiro IBL; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; The Marine Science Institute, University of the Philippines, Quezon City 1101, Philippines., Imperial JS; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Leavitt LS; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Phan J; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Fisher FA; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Watkins M; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Raghuraman S; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Tun JO; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Ueberheide BM; Departments of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10016, USA., McIntosh JM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.; Department of Psychiatry, University of Utah, Salt Lake City, UT 84108, USA.; Mental Health Department, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA., Vasconcelos V; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR-LA), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.; Faculty of Sciences, University of Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal., Olivera BM; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Gajewiak J; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.

المصدر: Marine drugs [Mar Drugs] 2024 Feb 29; Vol. 22 (3). Date of Electronic Publication: 2024 Feb 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-3397 (Electronic) Linking ISSN: 16603397 NLM ISO Abbreviation: Mar Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Conus Snail* , Conotoxins* , Receptors, Nicotinic*, Animals ; Mice ; Calcium ; Amino Acid Sequence ; alpha7 Nicotinic Acetylcholine Receptor

المؤلفون: Wu X; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland, 4072, Australia.; School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, 4072, Australia., Hone AJ; School of Biological Science, University of Utah, Salt Lake City, Utah, 84112, USA.; MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah, 84112, USA., Huang YH; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland, 4072, Australia., Clark RJ; School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, 4072, Australia., McIntosh JM; School of Biological Science, University of Utah, Salt Lake City, Utah, 84112, USA.; Department of Psychiatry, University of Utah, Salt Lake City, Utah, 84112, USA.; George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah, 84112, USA., Kaas Q; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland, 4072, Australia., Craik DJ; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland, 4072, Australia.

المصدر: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Feb 01; Vol. 30 (7), pp. e202302909. Date of Electronic Publication: 2023 Dec 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

مواضيع طبية MeSH: Conotoxins*/chemistry , Receptors, Nicotinic*/genetics , Receptors, Nicotinic*/chemistry , Receptors, Nicotinic*/metabolism, Nicotinic Antagonists/chemistry ; Mutation ; Molecular Dynamics Simulation

المؤلفون: Hone AJ; School of Biological Sciences University of Utah, Salt Lake City, UT, USA; MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA. Electronic address: uuneurotox@yahoo.com., McIntosh JM; School of Biological Sciences University of Utah, Salt Lake City, UT, USA; Department of Psychiatry, University of Utah, Salt Lake City, UT, USA; George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA. Electronic address: mcintosh.mike@gmail.com.

المصدر: Pharmacological research [Pharmacol Res] 2023 Apr; Vol. 190, pp. 106715. Date of Electronic Publication: 2023 Mar 01.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Nicotinic*/metabolism, Humans ; Pain/drug therapy ; Acetylcholine/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Signal Transduction ; Ligands

المؤلفون: Hone AJ; School of Biological Sciences, University of Utah, Salt Lake City, UT, United States.; MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, United States., McIntosh JM; School of Biological Sciences, University of Utah, Salt Lake City, UT, United States.; Department of Psychiatry, University of Utah, Salt Lake City, UT, United States.; George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, United States.

المصدر: Frontiers in pharmacology [Front Pharmacol] 2022 Sep 16; Vol. 13, pp. 981760. Date of Electronic Publication: 2022 Sep 16 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

المؤلفون: Jiménez-Pompa A; Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, Madrid, Spain; Instituto-Fundación Teófilo Hernando, Universidad Autónoma de Madrid, Madrid, Spain., Sanz-Lázaro S; Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, Madrid, Spain., Hone AJ; Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, Madrid, Spain; School of Biological Sciences and Department of Psychiatry, University of Utah, Salt Lake City, Utah, USA., Rueda-Ruzafa L; Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, Madrid, Spain., Medina-Polo J; Servicio de Urología, Hospital Universitario 12 de Octubre, Instituto de Investigación I+12, Madrid, Spain., González-Enguita C; Servicio de Urología y Unidad de Trasplante Renal, Fundación Jiménez Díaz, Madrid, Spain., Blázquez J; Servicio de Urología, Hospital Clínico San Carlos, Madrid, Spain., de Los Ríos C; Instituto-Fundación Teófilo Hernando, Universidad Autónoma de Madrid, Madrid, Spain., Michael McIntosh J; School of Biological Sciences and Department of Psychiatry, University of Utah, Salt Lake City, Utah, USA., Albillos A; Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, Madrid, Spain; Instituto Ramón y Cajal de Investigación Biosanitaria (IRYCIS), Madrid, Spain. Electronic address: almudena.albillos@uam.es.

المصدر: Neuropharmacology [Neuropharmacology] 2021 Sep 01; Vol. 195, pp. 108632. Date of Electronic Publication: 2021 Jun 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

مواضيع طبية MeSH: Catecholamines/*metabolism , Chromaffin Cells/*drug effects , Exocytosis/*drug effects , Nicotine/*pharmacology , Nicotinic Agonists/*pharmacology , Varenicline/*pharmacology, Acetylcholine/pharmacology ; Adrenal Glands/drug effects ; Adrenal Glands/metabolism ; Animals ; Cattle ; Chromaffin Cells/metabolism ; Humans ; Rats

المؤلفون: Hone AJ; MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah 84148 United States., Kaas Q; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072 Australia., Kearns I, Hararah F, Gajewiak J, Christensen S, Craik DJ; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072 Australia., McIntosh JM; George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah 84148 United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2021 Feb 11; Vol. 64 (3), pp. 1685-1700. Date of Electronic Publication: 2021 Feb 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Nicotinic Antagonists/*chemical synthesis , Nicotinic Antagonists/*pharmacology , Receptors, Nicotinic/*drug effects , Receptors, Nicotinic/*metabolism, Animals ; Conotoxins/pharmacology ; Drug Design ; Humans ; Ligands ; Models, Molecular ; Molecular Dynamics Simulation ; Neuralgia/drug therapy ; Oocytes/drug effects ; Peptides/chemical synthesis ; Peptides/pharmacology ; Rats ; Receptors, Nicotinic/chemistry ; Xenopus laevis

المؤلفون: Rueda Ruzafa L; Laboratory of Neuroscience, Biomedical Research Center (CINBIO), University of Vigo, 36310 Vigo, Spain., Cedillo JL; Department of Pharmacology and Therapeutics, Universidad Autónoma de Madrid, 28034 Madrid, Spain., Hone AJ; MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA.; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.

المصدر: International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Jan 29; Vol. 18 (3). Date of Electronic Publication: 2021 Jan 29.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601 (Electronic) Linking ISSN: 16604601 NLM ISO Abbreviation: Int J Environ Res Public Health Subsets: MEDLINE

مواضيع طبية MeSH: Gastrointestinal Microbiome*, Inflammatory Bowel Diseases/*physiopathology , Receptors, Nicotinic/*physiology, Brain/physiology ; Humans ; Inflammatory Bowel Diseases/microbiology ; Vagus Nerve

المؤلفون: Rueda-Ruzafa L; Laboratory of Neuroscience, CINBIO, University of Vigo, Campus Lagoas-Marcosende, 36310, Vigo, Spain., Cruz F; Department of Organic Chemistry, Faculty of Chemistry, University of Vigo, Campus Lagoas-Marcosende, 36310, Vigo, Spain., Cardona D; Department of Nursing Science, Physiotherapy and Medicine, University of Almería, Ctra. Sacramento s/n, La Cañada, 04120, Almería, Spain; Health Research Center. University of Almería, Spain. Electronic address: dcardona@ual.es., Hone AJ; MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT, USA; School of Biological Sciences, University of Utah, Salt Lake City, UT, USA., Molina-Torres G; Department of Physical Therapy, University of Granada - Campus of Melilla, C/Santander, 1, 52005, Melilla, Spain., Sánchez-Labraca N; Department of Nursing Science, Physiotherapy and Medicine, University of Almería, Ctra. Sacramento s/n, La Cañada, 04120, Almería, Spain., Roman P; Department of Nursing Science, Physiotherapy and Medicine, University of Almería, Ctra. Sacramento s/n, La Cañada, 04120, Almería, Spain; Health Research Center. University of Almería, Spain; Health Sciences Research Group (CTS-451), University of Almería, Spain.

المصدر: Pharmacological research [Pharmacol Res] 2020 Sep; Vol. 159, pp. 104928. Date of Electronic Publication: 2020 Jun 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE

مواضيع طبية MeSH: Analgesics, Opioid/*adverse effects , Bacteria/*drug effects , Brain/*drug effects , Gastrointestinal Microbiome/*drug effects , Intestines/*microbiology , Morphine/*adverse effects , Peptides/*adverse effects , Receptors, Opioid/*drug effects, Animals ; Bacteria/metabolism ; Brain/metabolism ; Brain/physiopathology ; Dietary Exposure/adverse effects ; Dysbiosis ; Humans ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/microbiology ; Neurodegenerative Diseases/physiopathology ; Neurodegenerative Diseases/therapy ; Probiotics/therapeutic use ; Receptors, Opioid/metabolism ; Signal Transduction