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المصدر: Nature. 578(7793):82

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:143672104

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المؤلفون: Hong EP; Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24254, Republic of Korea., Lim SH; Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24254, Republic of Korea., Youn DH; Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24254, Republic of Korea., Han SW; Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24254, Republic of Korea., Jung H; Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24254, Republic of Korea., Lee JJ; Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24254, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Hallym University College of Medicine, Chuncheon 24253, Republic of Korea., Jeon JP; Department of Neurosurgery, Hallym University College of Medicine, 77 Sakju-ro, Chuncheon 24253, Republic of Korea., On Behalf Of The First Korean Stroke Genetics Association Research The FirstKSGAR Study

المصدر: Biomedicines [Biomedicines] 2024 Jun 22; Vol. 12 (7). Date of Electronic Publication: 2024 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE

المؤلفون: Choi DE; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Neurology, Harvard Medical School, Boston, United States., Shin JW; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Neurology, Harvard Medical School, Boston, United States., Zeng S; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States., Hong EP; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Neurology, Harvard Medical School, Boston, United States.; Medical and Population Genetics Program, The Broad Institute of MIT and Harvard, Cambridge, United States., Jang JH; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Neurology, Harvard Medical School, Boston, United States., Loupe JM; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Neurology, Harvard Medical School, Boston, United States., Wheeler VC; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Neurology, Harvard Medical School, Boston, United States., Stutzman HE; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Pathology, Massachusetts General Hospital, Boston, United States., Kleinstiver B; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Pathology, Massachusetts General Hospital, Boston, United States.; Department of Pathology, Harvard Medical School, Boston, United States., Lee JM; Center for Genomic Medicine, Massachusetts General Hospital, Boston, United States.; Department of Neurology, Harvard Medical School, Boston, United States.; Medical and Population Genetics Program, The Broad Institute of MIT and Harvard, Cambridge, United States.

المصدر: ELife [Elife] 2024 Jun 13; Vol. 12. Date of Electronic Publication: 2024 Jun 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/genetics , Huntington Disease*/therapy , Gene Editing*/methods , Huntingtin Protein*/genetics , Huntingtin Protein*/metabolism , Trinucleotide Repeat Expansion*/genetics, Animals ; Mice ; Disease Models, Animal ; Humans ; Mutation ; Gene Knock-In Techniques

المؤلفون: Kim KH; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Department of Neurology, Harvard Medical School, Boston, MA 02115., Hong EP; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Department of Neurology, Harvard Medical School, Boston, MA 02115., Lee Y; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Department of Neurology, Harvard Medical School, Boston, MA 02115., McLean ZL; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Department of Neurology, Harvard Medical School, Boston, MA 02115.; Medical and Population Genetics Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142., Elezi E; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114., Lee R; CHDI Foundation, Princeton, NJ 08540., Kwak S; CHDI Foundation, Princeton, NJ 08540., McAllister B; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, United Kingdom., Massey TH; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, United Kingdom., Lobanov S; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, United Kingdom., Holmans P; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, United Kingdom., Orth M; University Hospital of Old Age Psychiatry and Psychotherapy, Bern University, CH-3000 Bern 60, Switzerland., Ciosi M; School of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom., Monckton DG; School of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom., Long JD; Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242.; Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242., Lucente D; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114., Wheeler VC; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Department of Neurology, Harvard Medical School, Boston, MA 02115., MacDonald ME; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Department of Neurology, Harvard Medical School, Boston, MA 02115.; Medical and Population Genetics Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142., Gusella JF; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Medical and Population Genetics Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115., Lee JM; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114.; Department of Neurology, Harvard Medical School, Boston, MA 02115.; Medical and Population Genetics Program, The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 16; Vol. 121 (16), pp. e2322924121. Date of Electronic Publication: 2024 Apr 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Huntington Disease*/genetics , MicroRNAs*/genetics, Humans ; 3' Untranslated Regions/genetics ; Endodeoxyribonucleases ; Exodeoxyribonucleases/genetics ; Genome-Wide Association Study ; Multifunctional Enzymes

المؤلفون: Hong EP; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.; Medical and Population Genetics Program, The Broad Institute of M.I.T. and Harvard, Cambridge, MA 02142, USA., Ramos EM; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA., Aziz NA; Population & Clinical Neuroepidemiology, German Center for Neurodegenerative Diseases, 53127 Bonn, Germany.; Department of Neurology, Faculty of Medicine, University of Bonn, Bonn D-53113, Germany., Massey TH; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK., McAllister B; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK., Lobanov S; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK., Jones L; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK., Holmans P; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK., Kwak S; Molecular System Biology, CHDI Foundation, Princeton, NJ 08540, USA., Orth M; University Hospital of Old Age Psychiatry and Psychotherapy, Bern University, CH-3000 Bern 60, Switzerland., Ciosi M; School of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Lomeikaite V; School of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Monckton DG; School of Molecular Biosciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Long JD; Department of Psychiatry, Carver College of Medicine and Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA., Lucente D; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Wheeler VC; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA., Gillis T; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., MacDonald ME; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.; Medical and Population Genetics Program, The Broad Institute of M.I.T. and Harvard, Cambridge, MA 02142, USA., Sequeiros J; UnIGENe, IBMC-Institute for Molecular and Cell Biology, i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto 420-135, Portugal.; ICBAS School of Medicine and Biomedical Sciences, University of Porto, Porto 420-135, Portugal., Gusella JF; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Medical and Population Genetics Program, The Broad Institute of M.I.T. and Harvard, Cambridge, MA 02142, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Lee JM; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.; Medical and Population Genetics Program, The Broad Institute of M.I.T. and Harvard, Cambridge, MA 02142, USA.

المصدر: Brain communications [Brain Commun] 2024 Jan 23; Vol. 6 (2), pp. fcae016. Date of Electronic Publication: 2024 Jan 23 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE