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1دورية أكاديمية
المؤلفون: Hanan S. Anbar, Mohammed I. El-Gamal, Hamadeh Tarazi, Bong S. Lee, Hong R. Jeon, Dow Kwon, Chang-Hyun Oh
المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1712-1726 (2020)
مصطلحات موضوعية: apoptosis, imidazothiazole, melanoma, modelling, v600e-b-raf, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2
المؤلفون: Bong Sang Lee, Hong R. Jeon, Dow Kwon, Chang-Hyun Oh, Mohammed I. El-Gamal, Hanan S. Anbar, Hamadeh Tarazi
المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1712-1726 (2020)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Recordمصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Imidazothiazole, Quantitative Structure-Activity Relationship, Antineoplastic Agents, RM1-950, Molecular Dynamics Simulation, 01 natural sciences, modelling, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Oximes, medicine, melanoma, Humans, Protein Kinase Inhibitors, v600e-b-raf, Cell Proliferation, Pharmacology, Sulfonamides, 010405 organic chemistry, Chemistry, Melanoma, Imidazoles, apoptosis, imidazothiazole, Raf kinase, General Medicine, Sorafenib, medicine.disease, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Thiazoles, Vemurafenib, Apoptosis, Cancer research, Molecular mechanism, Carbamates, Therapeutics. Pharmacology, Drug Screening Assays, Antitumor, Imidazothiazole derivatives, V600E, Research Article, Research Paper
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3
المؤلفون: Eslam M.H. Ali, Garam Kim, Young Jik Kwon, Usama M. Ammar, Dong Keun Han, Mahmoud M. Gamal El-Din, Karim I. Mersal, Hong R. Jeon, Bong Sang Lee, Kyung-Tae Lee, Kyung Ho Yoo, Jae Kyun Lee, Mohammed I. El-Gamal, Kwan Hyi Lee, Hong Seok Choi, Chang Hyun Oh, Dow Kwon, Mohammed S. Abdel-Maksoud
مصطلحات موضوعية: MAPK/ERK pathway, Kinase, Cellular Assay, chemistry.chemical_compound, chemistry, Biochemistry, In vivo, Drug Discovery, Cancer cell, Molecular Medicine, Thiazole, RB, Sulfamide, V600E
وصف الملف: application/pdf
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4
المؤلفون: Mohammed S, Abdel-Maksoud, Mohammed I, El-Gamal, Bong S, Lee, Mahmoud M, Gamal El-Din, Hong R, Jeon, Dow, Kwon, Usama M, Ammar, Karim I, Mersal, Eslam M H, Ali, Kyung-Tae, Lee, Kyung Ho, Yoo, Dong Keun, Han, Jae Kyun, Lee, Garam, Kim, Hong Seok, Choi, Young Jik, Kwon, Kwan Hyi, Lee, Chang Hyun, Oh
المصدر: Journal of medicinal chemistry. 64(10)
مصطلحات موضوعية: Mitogen-Activated Protein Kinase Kinases, Proto-Oncogene Proteins B-raf, Sulfonamides, Binding Sites, Transplantation, Heterologous, Drug Evaluation, Preclinical, Imidazoles, Molecular Docking Simulation, Mice, Structure-Activity Relationship, Thiazoles, Drug Stability, Cell Line, Tumor, Animals, Humans, Drug Screening Assays, Antitumor, Phosphorylation, Melanoma, Protein Kinase Inhibitors, Cell Proliferation, Half-Life