المؤلفون: Tao Y; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan, United States of America., Feng F; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America., Luo X; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America., Reihsmann CV; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Hopkirk AL; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Cartailler JP; Center for Stem Cell Biology, Vanderbilt University, Nashville, Tennessee, United States of America., Brissova M; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Parker SCJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America., Saunders DC; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Liu J; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America.

المصدر: PLoS computational biology [PLoS Comput Biol] 2024 Aug 28; Vol. 20 (8), pp. e1012344. Date of Electronic Publication: 2024 Aug 28 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Computational Biology*/methods , Image Processing, Computer-Assisted*/methods, Humans ; Single-Cell Analysis/methods ; Algorithms ; Software

المؤلفون: Walker JT; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA., Saunders DC; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Rai V; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Chen HH; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Orchard P; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Dai C; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Pettway YD; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA., Hopkirk AL; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Reihsmann CV; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Tao Y; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Fan S; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Shrestha S; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Varshney A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Petty LE; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Wright JJ; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Ventresca C; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Agarwala S; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Aramandla R; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Poffenberger G; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Jenkins R; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Mei S; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Hart NJ; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Phillips S; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Kang H; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Greiner DL; Department of Molecular Medicine, Diabetes Center of Excellence, University of Massachusetts Medical School, Worcester, MA, USA., Shultz LD; The Jackson Laboratory, Bar Harbor, ME, USA., Bottino R; Imagine Pharma, Devon, PA, USA.; Institute of Cellular Therapeutics, Allegheny-Singer Research Institute, Allegheny Health Network, Pittsburgh, PA, USA., Liu J; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Below JE; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Parker SCJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. scjp@umich.edu.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA. scjp@umich.edu.; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA. scjp@umich.edu., Powers AC; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA. al.powers@vumc.org.; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. al.powers@vumc.org.; VA Tennessee Valley Healthcare System, Nashville, TN, USA. al.powers@vumc.org., Brissova M; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. marcela.brissova@vanderbilt.edu.

مؤلفون مشاركون: HPAP Consortium

المصدر: Nature [Nature] 2023 Dec; Vol. 624 (7992), pp. 621-629. Date of Electronic Publication: 2023 Dec 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/pathology , Diabetes Mellitus, Type 2*/physiopathology , Gene Expression Profiling* , Gene Regulatory Networks*/genetics , Genetic Predisposition to Disease* , Islets of Langerhans*/metabolism , Islets of Langerhans*/pathology, Humans ; Case-Control Studies ; Cell Separation ; Chromatin/metabolism ; Genome-Wide Association Study ; Insulin Secretion ; Reproducibility of Results

المؤلفون: Zhu H; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA., Wang G; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA., Nguyen-Ngoc KV; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA., Kim D; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA., Miller M; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Goss G; Centre for Gene Therapy and Regenerative Medicine, King's College London, London SE1 9RT, UK., Kovsky J; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA., Harrington AR; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA., Saunders DC; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232-0475, USA., Hopkirk AL; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232-0475, USA., Melton R; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA., Powers AC; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232-0475, USA; Department of Molecular Physiology & Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232-0615, USA; VA Tennessee Valley Healthcare System, Nashville, TN 37212-2637, USA., Preissl S; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA., Spagnoli FM; Centre for Gene Therapy and Regenerative Medicine, King's College London, London SE1 9RT, UK., Gaulton KJ; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA., Sander M; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093-0653, USA; Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA. Electronic address: maike.sander@mdc-berlin.de.

المصدر: Developmental cell [Dev Cell] 2023 May 08; Vol. 58 (9), pp. 727-743.e11. Date of Electronic Publication: 2023 Apr 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

مواضيع طبية MeSH: Islets of Langerhans* , Insulin-Secreting Cells* , Pluripotent Stem Cells*, Adult ; Humans ; Pancreas ; Cell Differentiation/genetics