المؤلفون: Poedts Stefaan, Kochanov Andrey, Lani Andrea, Scolini Camilla, Verbeke Christine, Hosteaux Skralan, Chané Emmanuel, Deconinck Herman, Mihalache Nicolae, Diet Fabian, Heynderickx Daniel, De Keyser Johan, De Donder Erwin, Crosby Norma B., Echim Marius, Rodriguez Luciano, Vansintjan Robbe, Verstringe Freek, Mampaey Benjamin, Horne Richard, Glauert Sarah, Jiggens Piers, Keil Ralf, Glover Alexi, Deprez Grégoire, Luntama Juha-Pekka

المصدر: Journal of Space Weather and Space Climate, Vol 10, p 14 (2020)

مصطلحات موضوعية: space weather models, heliospheric-esc, operational modelling centre, Meteorology. Climatology, QC851-999

وصف الملف: electronic resource

Relation: https://www.swsc-journal.org/articles/swsc/full_html/2020/01/swsc190070/swsc190070.html; https://doaj.org/toc/2115-7251

URL الوصول: https://doaj.org/article/2377ec8bfefa41ec9dc1c2e3c38c6597

المؤلفون: Poedts Stefaan, Maget Vincent, Sicard Angelica, Boscher Daniel, Amariutei Olga A., Ganushkina Natalia Y., Afanasiev Alexandr, Vainio Rami, Koskinen Hannu, Meredith Nigel P., Glauert Sarah A., Horne Richard B., Jacobs Carla, Sanahuja Blai, Aran Angels, Heynderickx Daniel, Pitchford David

المصدر: Journal of Space Weather and Space Climate, Vol 3, p A20 (2013)

مصطلحات موضوعية: Radiation belts, SEP events, Satellites, Meteorology. Climatology, QC851-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2115-7251

URL الوصول: https://doaj.org/article/75c6fcfd5c3a443ab08447a7768f9290

المؤلفون: Horne RI; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Andrzejewska EA; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Alam P; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Brotzakis ZF; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Srivastava A; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Aubert A; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Nowinska M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Gregory RC; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Staats R; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Possenti A; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Chia S; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Sormanni P; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Caughey B; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Knowles TPJ; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK. mv245@cam.ac.uk.

المصدر: Nature chemical biology [Nat Chem Biol] 2024 May; Vol. 20 (5), pp. 634-645. Date of Electronic Publication: 2024 Apr 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: alpha-Synuclein*/antagonists & inhibitors , alpha-Synuclein*/metabolism , alpha-Synuclein*/chemistry , Machine Learning* , Drug Discovery*/methods , Protein Aggregates*/drug effects, Humans ; Small Molecule Libraries/pharmacology ; Small Molecule Libraries/chemistry ; Parkinson Disease/drug therapy ; Parkinson Disease/metabolism ; Structure-Activity Relationship

المؤلفون: Dear AJ; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Teng X; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Ball SR; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Lewin J; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Horne RI; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Clow D; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Stevenson A; Department of Biology, Institute of Biochemistry, ETH Zurich Otto Stern Weg 3 8093 Zurich Switzerland.; Bringing Materials to Life Initiative, ETH Zurich Switzerland., Harper N; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Yahya K; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Yang X; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Brewerton SC; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Thomson J; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Michaels TCT; Department of Biology, Institute of Biochemistry, ETH Zurich Otto Stern Weg 3 8093 Zurich Switzerland.; Bringing Materials to Life Initiative, ETH Zurich Switzerland., Linse S; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com.; Biochemistry and Structural Biology, Lund University Lund Sweden., Knowles TPJ; Yusuf Hamied Department of Chemistry, University of Cambridge Cambridge UK.; Cavendish Laboratory, University of Cambridge Cambridge UK., Habchi J; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com., Meisl G; WaveBreak Therapeutics Ltd, Chemistry of Health Lensfield Road Cambridge CB2 1EW UK georg.meisl@googlemail.com.

المصدر: Chemical science [Chem Sci] 2024 Apr 22; Vol. 15 (19), pp. 7229-7242. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

المؤلفون: Horne RI; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Wilson-Godber J; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., González Díaz A; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Brotzakis ZF; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Seal S; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States., Gregory RC; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Possenti A; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Chia S; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 138668 Singapore, Singapore., Vendruscolo M; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2024 Feb 12; Vol. 64 (3), pp. 590-596. Date of Electronic Publication: 2024 Jan 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: alpha-Synuclein*/chemistry , Drug Discovery*, Biological Availability ; Small Molecule Libraries/pharmacology

المؤلفون: Chandra R; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Horne RI; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.

المصدر: Journal of chemical theory and computation [J Chem Theory Comput] 2024 Jan 09; Vol. 20 (1), pp. 469-476. Date of Electronic Publication: 2023 Dec 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101232704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-9626 (Electronic) Linking ISSN: 15499618 NLM ISO Abbreviation: J Chem Theory Comput Subsets: MEDLINE

مواضيع طبية MeSH: fms-Like Tyrosine Kinase 3* , Drug Design*, Bayes Theorem

المؤلفون: Sandler SE; Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge CB3 0HE, U.K., Horne RI; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Rocchetti S; Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge CB3 0HE, U.K., Novak R; Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge CB3 0HE, U.K., Hsu NS; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Castellana Cruz M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Faidon Brotzakis Z; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Gregory RC; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Chia S; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.; Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore 138668., Bernardes GJL; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Keyser UF; Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge CB3 0HE, U.K., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2023 Nov 29; Vol. 145 (47), pp. 25776-25788. Date of Electronic Publication: 2023 Nov 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Nanopores* , Parkinson Disease*/metabolism, Humans ; alpha-Synuclein/metabolism

المؤلفون: Horne RI; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Metrick MA 2nd; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Man W; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Rinauro DJ; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Brotzakis ZF; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Chia S; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Bioprocessing Technology Institute, Agency of Science, Technology and Research (A*STAR), 138668, Singapore., Meisl G; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2023 Sep 06; Vol. 14 (17), pp. 3125-3131. Date of Electronic Publication: 2023 Aug 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: alpha-Synuclein* , Salts*, Reproducibility of Results ; Hydrogen-Ion Concentration ; Sodium

المؤلفون: Staats R; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Brotzakis ZF; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Chia S; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Horne RI; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom.

المصدر: Frontiers in molecular biosciences [Front Mol Biosci] 2023 Aug 28; Vol. 10, pp. 1155753. Date of Electronic Publication: 2023 Aug 28 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653173 Publication Model: eCollection Cited Medium: Print ISSN: 2296-889X (Print) Linking ISSN: 2296889X NLM ISO Abbreviation: Front Mol Biosci Subsets: PubMed not MEDLINE

المؤلفون: Horne RI; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Murtada MH; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Huo D; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China., Brotzakis ZF; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Gregory RC; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Possenti A; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Chia S; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Bioprocessing Technology Institute, Agency of Science, Technology and Research (A*STAR), Singapore 138668, Singapore., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.

المصدر: Journal of chemical theory and computation [J Chem Theory Comput] 2023 Jul 25; Vol. 19 (14), pp. 4701-4710. Date of Electronic Publication: 2023 Mar 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101232704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-9626 (Electronic) Linking ISSN: 15499618 NLM ISO Abbreviation: J Chem Theory Comput Subsets: MEDLINE

مواضيع طبية MeSH: alpha-Synuclein* , Parkinson Disease*/drug therapy, Humans ; Drug Discovery ; Kinetics