لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Riva L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Yuan S; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Yin X; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Martin-Sancho L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Matsunaga N; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Pache L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Burgstaller-Muehlbacher S; Center for Integrative Bioinformatics Vienna, Max Perutz Laboratories, University of Vienna and Medical University of Vienna, Vienna, Austria., De Jesus PD; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Teriete P; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Hull MV; Calibr at Scripps Research, La Jolla, CA, USA., Chang MW; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Chan JF; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Cao J; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Poon VK; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Herbert KM; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Cheng K; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, USA.; Biological Sciences Graduate Program, University of Maryland, College Park, MD, USA., Nguyen TH; Calibr at Scripps Research, La Jolla, CA, USA., Rubanov A; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Pu Y; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Nguyen C; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Choi A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Rathnasinghe R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Schotsaert M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Miorin L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dejosez M; Huffington Foundation Center for Cell-based Research in Parkinson's Disease, Department for Cell, Regenerative and Developmental Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zwaka TP; Huffington Foundation Center for Cell-based Research in Parkinson's Disease, Department for Cell, Regenerative and Developmental Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sit KY; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, TX, USA., Liu WC; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., White KM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chapman ME; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Lendy EK; Department of Biochemistry, Purdue University, West Lafayette, IN, USA., Glynne RJ; Inception Therapeutics, San Diego, CA, USA., Albrecht R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ruppin E; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, USA., Mesecar AD; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.; Department of Biochemistry, Purdue University, West Lafayette, IN, USA., Johnson JR; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Benner C; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Sun R; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, USA., Schultz PG; Calibr at Scripps Research, La Jolla, CA, USA., Su AI; Department of Integrative, Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chatterjee AK; Calibr at Scripps Research, La Jolla, CA, USA. achatterjee@scripps.edu., Yuen KY; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China. kyyuen@hku.hk.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China. kyyuen@hku.hk.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China. kyyuen@hku.hk., Chanda SK; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. schanda@sbpdiscovery.org.

المصدر: Nature [Nature] 2024 Jul; Vol. 631 (8019), pp. E3.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Carucci M; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France., Duez J; SYNSIGHT, 91000, Evry-Courcouronnes, France., Tarning J; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 10400, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., García-Barbazán I; Mycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28222, Madrid, Spain., Fricot-Monsinjon A; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France., Sissoko A; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France., Dumas L; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France., Gamallo P; Global Health Medicines R&D, GlaxoSmith Kline (GSK), 28760, Tres Cantos, Spain., Beher B; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France., Amireault P; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France.; Laboratory of cellular and molecular mechanisms of hematological disorders and therapeutic implications, INSERM, 75014, Paris, France., Dussiot M; Laboratory of cellular and molecular mechanisms of hematological disorders and therapeutic implications, INSERM, 75014, Paris, France.; Laboratoire d'Excellence GR-Ex, Paris, France., Dao M; Department of Materials Science and Engineering, Massachusetts Institute of Technology, MA, 02139, Cambridge, USA., Hull MV; Calibr, a division of The Scripps Research Institute, La Jolla, CA, 92037, USA., McNamara CW; Calibr, a division of The Scripps Research Institute, La Jolla, CA, 92037, USA., Roussel C; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France.; Laboratoire d'Excellence GR-Ex, Paris, France.; Laboratoire d'Hématologie générale, Hôpital Universitaire Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris (AP-HP), 75015, Paris, France., Ndour PA; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France., Sanz LM; Global Health Medicines R&D, GlaxoSmith Kline (GSK), 28760, Tres Cantos, Spain., Gamo FJ; Global Health Medicines R&D, GlaxoSmith Kline (GSK), 28760, Tres Cantos, Spain., Buffet P; Université Paris Cité, Inserm, UMR-1134, Biologie Intégré du Globule Rouge, 75015, Paris, France. pierre.buffet@inserm.fr.; Department of Infectious & Tropical Disease, AP-HP, Necker Hospital, 75015, Paris, France. pierre.buffet@inserm.fr.; Centre Médical de l'Institut Pasteur (CMIP), Institut Pasteur, 75015, Paris, France. pierre.buffet@inserm.fr.

المصدر: Nature communications [Nat Commun] 2023 Apr 07; Vol. 14 (1), pp. 1951. Date of Electronic Publication: 2023 Apr 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials*/pharmacology , Malaria, Falciparum*/parasitology, Humans ; Spleen ; Plasmodium falciparum ; Erythrocytes/parasitology

المؤلفون: Bakowski MA; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA. mbakowski@scripps.edu., Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Wolff KC; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Kirkpatrick MG; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Chen E; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Nguyen TH; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Riva L; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Shaabani N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Parren M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Ricketts J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Gupta AK; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Pan K; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Kuo P; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Fuller M; Department of Cellular and Molecular Medicine, UC San Diego, La Jolla, CA, USA.; HUMANOID CoRE, UC San Diego, La Jolla, CA, USA., Garcia E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Teijaro JR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Yang L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Sahoo D; Department of Computer Science and Engineering, Jacobs School of Engineering, UC San Diego, La Jolla, CA, USA.; Department of Pediatrics, UC San Diego, La Jolla, CA, USA., Chi V; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Huang E; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Vargas N; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Roberts AJ; Animal Models Core Facility, The Scripps Research Institute, La Jolla, CA, USA., Das S; HUMANOID CoRE, UC San Diego, La Jolla, CA, USA.; Department of Pathology, UC San Diego, La Jolla, CA, USA., Ghosh P; Department of Cellular and Molecular Medicine, UC San Diego, La Jolla, CA, USA.; HUMANOID CoRE, UC San Diego, La Jolla, CA, USA.; Department of Medicine, UC San Diego, La Jolla, CA, USA., Woods AK; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Joseph SB; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Hull MV; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Schultz PG; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Chatterjee AK; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., McNamara CW; Calibr, a division of The Scripps Research Institute, La Jolla, CA, USA., Rogers TF; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. trogers@scripps.edu.; UC San Diego Division of Infectious Diseases and Global Public Health, UC San Diego School of Medicine, La Jolla, CA, USA. trogers@scripps.edu.

المصدر: Nature communications [Nat Commun] 2021 Jun 03; Vol. 12 (1), pp. 3309. Date of Electronic Publication: 2021 Jun 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Pandemics* , SARS-CoV-2*/drug effects , SARS-CoV-2*/physiology , COVID-19 Drug Treatment*, Antiviral Agents/*pharmacology , Drug Repositioning/*methods, Animals ; COVID-19/prevention & control ; COVID-19/virology ; Cell Line ; Cytidine/administration & dosage ; Cytidine/analogs & derivatives ; Cytidine/pharmacology ; Databases, Pharmaceutical ; Drug Discovery/methods ; Drug Evaluation, Preclinical/methods ; HeLa Cells ; High-Throughput Screening Assays/methods ; Humans ; Hydroxylamines/administration & dosage ; Hydroxylamines/pharmacology ; Mesocricetus ; Nelfinavir/pharmacology ; Virus Replication/drug effects

المؤلفون: Garnar-Wortzel L; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Bishop TR; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Kitamura S; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Milosevich N; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Asiaban JN; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Zhang X; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Zheng Q; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Chen E; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Ramos AR; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Ackerman CJ; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Hampton EN; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Chatterjee AK; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Young TS; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Hull MV; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Sharpless KB; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Wolan DW; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Erb MA; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.

المصدر: ACS central science [ACS Cent Sci] 2021 May 26; Vol. 7 (5), pp. 815-830. Date of Electronic Publication: 2021 Apr 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101660035 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2374-7943 (Print) Linking ISSN: 23747943 NLM ISO Abbreviation: ACS Cent Sci Subsets: PubMed not MEDLINE

المؤلفون: Wall G; Department of Biology and The South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, United States., Chen E; Calibr, a division of The Scripps Research Institute, La Jolla, CA, United States., Hull MV; Calibr, a division of The Scripps Research Institute, La Jolla, CA, United States., Lopez-Ribot JL; Department of Biology and The South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, United States.

المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2020 Nov 25; Vol. 10, pp. 597931. Date of Electronic Publication: 2020 Nov 25 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Candida* , Candidiasis*/drug therapy, Antifungal Agents/pharmacology ; Biofilms ; Humans

المؤلفون: Riva L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Yuan S; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Yin X; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Martin-Sancho L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Matsunaga N; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Pache L; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Burgstaller-Muehlbacher S; Center for Integrative Bioinformatics Vienna, Max Perutz Laboratories, University of Vienna and Medical University of Vienna, Vienna, Austria., De Jesus PD; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Teriete P; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Hull MV; Calibr at Scripps Research, La Jolla, CA, USA., Chang MW; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Chan JF; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Cao J; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Poon VK; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Herbert KM; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Cheng K; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, USA.; Biological Sciences Graduate Program, University of Maryland, College Park, MD, USA., Nguyen TH; Calibr at Scripps Research, La Jolla, CA, USA., Rubanov A; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Pu Y; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Nguyen C; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Choi A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Rathnasinghe R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Schotsaert M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Miorin L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dejosez M; Huffington Foundation Center for Cell-based Research in Parkinson's Disease, Department for Cell, Regenerative and Developmental Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zwaka TP; Huffington Foundation Center for Cell-based Research in Parkinson's Disease, Department for Cell, Regenerative and Developmental Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sit KY; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China., Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, TX, USA., Liu WC; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., White KM; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chapman ME; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Lendy EK; Department of Biochemistry, Purdue University, West Lafayette, IN, USA., Glynne RJ; Inception Therapeutics, San Diego, CA, USA., Albrecht R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ruppin E; Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, USA., Mesecar AD; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.; Department of Biochemistry, Purdue University, West Lafayette, IN, USA., Johnson JR; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Benner C; Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Sun R; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, USA., Schultz PG; Calibr at Scripps Research, La Jolla, CA, USA., Su AI; Department of Integrative, Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chatterjee AK; Calibr at Scripps Research, La Jolla, CA, USA. achatterjee@scripps.edu., Yuen KY; State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China. kyyuen@hku.hk.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China. kyyuen@hku.hk.; Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China. kyyuen@hku.hk., Chanda SK; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. schanda@sbpdiscovery.org.

المصدر: Nature [Nature] 2020 Oct; Vol. 586 (7827), pp. 113-119. Date of Electronic Publication: 2020 Jul 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Drug Evaluation, Preclinical* , Drug Repositioning*, Antiviral Agents/*analysis , Antiviral Agents/*pharmacology , Betacoronavirus/*drug effects , Coronavirus Infections/*drug therapy , Coronavirus Infections/*virology , Pneumonia, Viral/*drug therapy , Pneumonia, Viral/*virology, Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/pharmacology ; Alanine/analogs & derivatives ; Alanine/pharmacology ; Alveolar Epithelial Cells/cytology ; Alveolar Epithelial Cells/drug effects ; Betacoronavirus/growth & development ; COVID-19 ; Cell Line ; Cysteine Proteinase Inhibitors/analysis ; Cysteine Proteinase Inhibitors/pharmacology ; Dose-Response Relationship, Drug ; Drug Synergism ; Gene Expression Regulation/drug effects ; Humans ; Hydrazones ; Induced Pluripotent Stem Cells/cytology ; Models, Biological ; Morpholines/analysis ; Morpholines/pharmacology ; Pandemics ; Pyrimidines ; Reproducibility of Results ; SARS-CoV-2 ; Small Molecule Libraries/analysis ; Small Molecule Libraries/pharmacology ; Triazines/analysis ; Triazines/pharmacology ; Virus Internalization/drug effects ; Virus Replication/drug effects ; COVID-19 Drug Treatment

المؤلفون: Rice CA; Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America.; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, United States of America., Colon BL; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, United States of America.; Department of Infectious Diseases, University of Georgia, Athens, Georgia, United States of America., Chen E; Calibr at Scripps Research, La Jolla, California, United States of America., Hull MV; Calibr at Scripps Research, La Jolla, California, United States of America., Kyle DE; Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America.; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, United States of America.; Department of Infectious Diseases, University of Georgia, Athens, Georgia, United States of America.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Sep 24; Vol. 14 (9), pp. e0008353. Date of Electronic Publication: 2020 Sep 24 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Amebiasis/*drug therapy , Amebicides/*pharmacology , Drug Repositioning/*methods , High-Throughput Screening Assays/*methods, Acanthamoeba/drug effects ; Balamuthia mandrillaris/drug effects ; Databases, Pharmaceutical ; Naegleria fowleri/drug effects ; Neglected Diseases/drug therapy ; Small Molecule Libraries

المؤلفون: Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M; Laboratory of Advanced Food Process Engineering, Osaka Prefecture University, 1-2, Gakuen-cho, Nakaku, Sakai, Osaka 599-8570, Japan., Cappiello JR, Kitamura S; Laboratory of Advanced Food Process Engineering, Osaka Prefecture University, 1-2, Gakuen-cho, Nakaku, Sakai, Osaka 599-8570, Japan., Nizet V, Sharpless KB, Wolan DW

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2020 Jun 24; Vol. 142 (25), pp. 10899-10904. Date of Electronic Publication: 2020 Jun 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*antagonists & inhibitors , Cysteine Proteinase Inhibitors/*pharmacology , Exotoxins/*antagonists & inhibitors , Sulfur Compounds/*chemistry, Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Catalytic Domain ; Click Chemistry ; Crystallography, X-Ray ; Cysteine Proteinase Inhibitors/metabolism ; Cysteine Proteinase Inhibitors/toxicity ; Drug Discovery ; Exotoxins/chemistry ; Exotoxins/metabolism ; High-Throughput Screening Assays ; Humans ; Jurkat Cells ; Microsomes, Liver/metabolism ; Proof of Concept Study ; Protein Binding