يعرض 1 - 10 نتائج من 14 نتيجة بحث عن '"Hunter P. Shunatona"', وقت الاستعلام: 1.13s تنقيح النتائج
  1. 1
    Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy

    المؤلفون: Jeffrey J. Jackson, Grant M. Shibuya, Buvana Ravishankar, Lavanya Adusumilli, Delia Bradford, Dirk G. Brockstedt, Cyril Bucher, Minna Bui, Cynthia Cho, Christoph Colas, Gene Cutler, Adrian Dukes, Xinping Han, Dennis X. Hu, Scott Jacobson, Paul D. Kassner, George E. Katibah, Michelle Yoo Min Ko, Urvi Kolhatkar, Paul R. Leger, Anqi Ma, Lisa Marshall, Jack Maung, Andrew A. Ng, Akinori Okano, Deepa Pookot, Daniel Poon, Chandru Ramana, Maureen K. Reilly, Omar Robles, Jacob B. Schwarz, Anton A. Shakhmin, Hunter P. Shunatona, Raashi Sreenivasan, Parcharee Tivitmahaisoon, Mengshu Xu, Thant Zaw, David J. Wustrow, Mikhail Zibinsky

    المصدر: Journal of Medicinal Chemistry. 65:12895-12924

    مصطلحات موضوعية: Mice, Knockout, Mice, eIF-2 Kinase, Myeloid-Derived Suppressor Cells, T-Lymphocytes, Drug Discovery, Animals, Molecular Medicine, Heme, Protein Serine-Threonine Kinases

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ef2aa8a880d39b628fb4a035cd9808
    https://doi.org/10.1021/acs.jmedchem.2c00736

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  2. 2
    Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors

    المؤلفون: Scott Jacobson, Dennis X. Hu, Cesar Meleza, Mikhail Zibinsky, Ashkaan Younai, Erin Riegler, Omar Robles, Jenny McKinnell, Emily Karbarz, Paul D. Kassner, Lisa A. Marshall, Maureen Kay Reilly, David Chian, Gene Cutler, David J. Wustrow, Dirk G. Brockstedt, Hunter P. Shunatona, Raymond Diokno, Angela Wadsworth, John M. Ketcham, Oezcan Talay, Jeffrey J. Jackson

    المصدر: Journal of Medicinal Chemistry. 63:8584-8607

    مصطلحات موضوعية: Chemokine, Receptors, CCR4, Population, CCR4, Antineoplastic Agents, chemical and pharmacologic phenomena, T-Lymphocytes, Regulatory, 01 natural sciences, 03 medical and health sciences, Chemokine receptor, Dogs, Immune system, Piperidines, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, CCL17, education, 030304 developmental biology, 0303 health sciences, Tumor microenvironment, education.field_of_study, biology, Chemistry, Immune checkpoint, 0104 chemical sciences, Macaca fascicularis, 010404 medicinal & biomolecular chemistry, biology.protein, Cancer research, Azetidines, Molecular Medicine, sense organs

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff8f25af0448a07583421b7d8d0bfa7
    https://doi.org/10.1021/acs.jmedchem.0c00988

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  3. 3
    Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment

    المؤلفون: Deepa Pookot, Scott Jacobson, John M. Ketcham, David Chian, Emily Karbarz, Dennis X. Hu, James Ross Walker, Gene Cutler, Ashkaan Younai, Mikhail Zibinsky, Raymond Diokno, David J. Wustrow, Betty Abraham, Angela Wadsworth, Maureen Kay Reilly, Cesar Meleza, Jenny McKinnell, Jeffrey J. Jackson, Abood Okal, Paul D. Kassner, Lisa A. Marshall, Oezcan Talay, Berenger Biannic, Bui Minna H T, Hilary Plake Beck, Hunter P. Shunatona, Omar Robles

    المصدر: Journal of Medicinal Chemistry. 62:6190-6213

    مصطلحات موضوعية: 0303 health sciences, Tumor microenvironment, education.field_of_study, Chemistry, Effector, Population, FOXP3, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Immune system, In vivo, Drug Discovery, Cancer research, Molecular Medicine, CCL17, education, CCL22, 030304 developmental biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::31c664d1b35dae60b88d59898f44ef53
    https://doi.org/10.1021/acs.jmedchem.9b00506

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  4. 4
    Discovery of a Potent and Selective CCR4 Antagonist That Inhibits T

    المؤلفون: Jeffrey J, Jackson, John M, Ketcham, Ashkaan, Younai, Betty, Abraham, Berenger, Biannic, Hilary P, Beck, Minna H T, Bui, David, Chian, Gene, Cutler, Raymond, Diokno, Dennis X, Hu, Scott, Jacobson, Emily, Karbarz, Paul D, Kassner, Lisa, Marshall, Jenny, McKinnell, Cesar, Meleza, Abood, Okal, Deepa, Pookot, Maureen K, Reilly, Omar, Robles, Hunter P, Shunatona, Oezcan, Talay, James R, Walker, Angela, Wadsworth, David J, Wustrow, Mikhail, Zibinsky

    المصدر: Journal of medicinal chemistry. 62(13)

    مصطلحات موضوعية: Receptors, CCR4, Molecular Structure, Mice, Transgenic, T-Lymphocytes, Regulatory, Piperazines, Rats, Structure-Activity Relationship, Cell Movement, Cyclohexanes, Pyrazines, Drug Discovery, Tumor Microenvironment, Animals, Humans, Pyrazoles

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::85180faa74d36bfcafdd7b76884ccac3
    https://pubmed.ncbi.nlm.nih.gov/31259550

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  5. 5
    Enantioselective Heck-Matsuda Arylations through Chiral Anion Phase-Transfer of Aryl Diazonium Salts

    المؤلفون: F. Dean Toste, Hosea M. Nelson, Hunter P. Shunatona, Carolina M. Avila, Masato Saito, Jigar S. Patel, Matthew S. Sigman, Yernaidu Reddi, Raghavan B. Sunoj

    المصدر: Avila, CM; Patel, JS; Reddi, Y; Saito, M; Nelson, HM; Shunatona, HP; et al.(2017). Enantioselective Heck–Matsuda Arylations through Chiral Anion Phase-Transfer of Aryl Diazonium Salts. Angewandte Chemie-International Edition, 56(21), 5806-5811. doi: 10.1002/anie.201702107. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3d76224w
    Angewandte Chemie (International ed. in English), vol 56, iss 21

    مصطلحات موضوعية: Anions, 010402 general chemistry, Medicinal chemistry, 01 natural sciences, Catalysis, Phase Transition, Article, chemistry.chemical_compound, Heck reaction, Cyclohexenes, Stereoselective-Synthesis, Acid, Cyclopentene, Organic chemistry, Arenediazonium-Salts, Acyclic Olefins, Phase-Transfer Catalysis, Heck Reaction, chemistry.chemical_classification, Heck-Matsuda Reaction, Chiral Anions, Molecular Structure, Phenol, Alkene, 010405 organic chemistry, Aryl, Transition-Metal Catalysis, Organic Chemistry, Heck-Matsuda reaction, chiral anions, Enantioselective synthesis, Stereoisomerism, General Chemistry, Heck–Matsuda reaction, General Medicine, Diazonium Compounds, palladium, Allylic Alcohols, Cross-Coupling Reactions, 0104 chemical sciences, chemistry, Desymmetrization, Chemical Sciences, Cycloheptene, phase-transfer catalysis, Alpha-Allylation, Palladium

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bcafd84b2d4b4580a644c2d08a5d90
    https://pubmed.ncbi.nlm.nih.gov/28418118

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  6. 6
    Chiral Anion Phase Transfer of Aryldiazonium Cations: An Enantioselective Synthesis of C3-Diazenated Pyrroloindolines

    المؤلفون: F. Dean Toste, Hunter P. Shunatona, Hosea M. Nelson, Jigar S. Patel, Solomon H. Reisberg

    المصدر: Angewandte Chemie (International ed. in English), vol 53, iss 22

    مصطلحات موضوعية: Tryptamine, Steric effects, Anions, cyclization, Indoles, Article, Catalysis, chemistry.chemical_compound, Cations, Organic chemistry, Pyrroles, Organic Chemistry, Enantioselective synthesis, asymmetric catalysis, amination, Stereoisomerism, General Chemistry, Diazonium Compounds, General Medicine, Combinatorial chemistry, Tryptamines, photolysis, chemistry, Cyclization, Yield (chemistry), Chemical Sciences, Electrophile, phase-transfer catalysis, Selectfluor

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62addace5215122b79151380a6d79435
    https://doi.org/10.1002/ange.201310905

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  7. 7
    Enantioselective Fluoroamination: 1,4-Addition to Conjugated Dienes Using Anionic Phase-Transfer Catalysis

    المؤلفون: F. Dean Toste, Yi-Ming Wang, Hunter P. Shunatona, Vivek Rauniyar, Natalja Früh

    المصدر: Angewandte Chemie International Edition. 52:7724-7727

    مصطلحات موضوعية: Enantioselective synthesis, General Medicine, General Chemistry, Conjugated system, Catalysis, chemistry.chemical_compound, chemistry, Phase (matter), Reagent, Organic chemistry, Amine gas treating, Isoquinoline, Selectfluor

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ad99066701f649e701317de8661cd0
    https://doi.org/10.1002/anie.201302002

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  8. 8
    Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: CC Bond Formation through Bimolecular Reductive Elimination

    المؤلفون: William E. Brenzovich, Aaron D. Lackner, William A. Goddard, F. Dean Toste, Hunter P. Shunatona, Diego Benitez, Ekaterina Tkatchouk

    المصدر: Angewandte Chemie. 122:5651-5654

    مصطلحات موضوعية: chemistry.chemical_classification, inorganic chemicals, Bromides, Alkene, Aryl, Homogeneous catalysis, General Chemistry, General Medicine, Alkenes, Photochemistry, Medicinal chemistry, Boronic Acids, Reductive elimination, Article, Catalysis, chemistry.chemical_compound, chemistry, Catalytic cycle, Cyclization, Intramolecular force, Gold, Selectfluor, Oxidation-Reduction

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023285341f2212c599c828b0265f700a
    https://doi.org/10.1002/ange.201002739

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  9. 9
    ChemInform Abstract: Enantioselective α-Amination Enabled by a BINAM-Derived Phase-Transfer Catalyst

    المؤلفون: Hunter P. Shunatona, Hosea M. Nelson, F. D. Toste, Jigar S. Patel

    المصدر: ChemInform. 46

    مصطلحات موضوعية: Scope (project management), Chemistry, Organocatalysis, Enantioselective synthesis, General Medicine, Phase-transfer catalyst, Combinatorial chemistry, Amination

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6c6e5e3eef6fbcae90d84389947265b
    https://doi.org/10.1002/chin.201523070

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  10. 10
    Enantioselective α-Amination Enabled by a BINAM-Derived Phase-Transfer Catalyst

    المؤلفون: Jigar S. Patel, Hunter P. Shunatona, Hosea M. Nelson, F. D. Toste

    المصدر: Chemical science, vol 6, iss 1

    مصطلحات موضوعية: Chemistry, Chemical Sciences, Enantioselective synthesis, Organic chemistry, General Chemistry, Phase-transfer catalyst, Amination

    وصف الملف: application/pdf; chemical/x-cif

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c944e75cded80418d022a509b50d916c
    https://escholarship.org/uc/item/1bp2r515

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