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المؤلفون: Engström, Gunnar, Janzon, Lars, Berglund, Göran, Lind, Peter, Stavenow, Lars, Hedblad, Bo, Lindgärde, Folke
المصدر: Arteriosclerosis, Thrombosis and Vascular Biology. 22(12):2054-2058
مصطلحات موضوعية: Hypertension: physiopathology, Hypertension: pathology, Hypertension: epidemiology, Hypertension: blood, Human, Follow-Up Studies, Non-U.S. Gov't, Cohort Studies, Blood Proteins: physiology, Blood Pressure: physiology, Antihypertensive Agents: therapeutic use, Aged, Age Factors, Systole: physiology, Adult, Incidence, Inflammation: blood, Inflammation: physiopathology, Male, Middle Age, Multivariate Analysis, Support, Medicin och hälsovetenskap, Klinisk medicin, Kardiologi, Medical and Health Sciences, Clinical Medicine, Cardiac and Cardiovascular Systems
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المؤلفون: Alessandra Rossini, Federico Quaini, Monia Savi, Stefano Rossi, Rossella Alinovi, Matteo Goldoni, Alessandra Pagliaro, Laura Gennaccaro, Donatella Stilli, Maricla Galetti, Caterina Frati, Marta Mazzola, Stéphane Lucas, Omar Lozano-Garcia, Antonio Mutti, Angela Falco, Michele Miragoli, Emilio Macchi, Viviana Meraviglia, Silvana Pinelli, Leonardo Bocchi
المصدر: Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-18 (2019)
Particle and Fibre Toxicology
Rossi, S, Savi, M, Mazzola, M, Pinelli, S, Alinovi, R, Gennaccaro, L, Pagliaro, A, Meraviglia, V, Galetti, M, Lozano-Garcia, O, Rossini, A, Frati, C, Falco, A, Quaini, F, Bocchi, L, Stilli, D, Lucas, S, Goldoni, M, Macchi, E, Mutti, A & Miragoli, M 2019, ' Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats ', Particle and Fibre Toxicology, vol. 16, no. 1, 25, pp. 25 . https://doi.org/10.1186/s12989-019-0311-7مصطلحات موضوعية: Myocardium/pathology, Cardiac fibrosis, Health, Toxicology and Mutagenesis, Left, Cardiac electrophysiology, Hemodynamics, Blood Pressure, Arrhythmias, Toxicology, Ventricular Function, Left, Lipid peroxidation, chemistry.chemical_compound, Electrocardiography, Hypertension/pathology, Heart Rate, Rats, Inbred SHR, Ventricular Function, Telemetry, Nanotoxicology, Titanium, Heart Rate/drug effects, Heart, Titanium dioxide nanoparticles, General Medicine, medicine.anatomical_structure, Hypertension, Cardiology, Drug, medicine.medical_specialty, Inbred SHR, lcsh:Industrial hygiene. Industrial welfare, Blood Pressure/drug effects, Dose-Response Relationship, Downregulation and upregulation, lcsh:RA1190-1270, Internal medicine, medicine, Animals, lcsh:Toxicology. Poisons, Lung, Dose-Response Relationship, Drug, business.industry, Myocardium, Research, medicine.disease, Nanoparticles/toxicity, Fibrosis, Heart/drug effects, Rats, chemistry, Heart failure, Nanoparticles, Titanium/toxicity, business, lcsh:HD7260-7780.8
وصف الملف: application/pdf
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المؤلفون: Cécile Aubert, Maithé Tauber, Ronan Roussel, Bénédicte Toussaint, François Pattou, Philippe Froguel, Jean-Michel Borys, Amjad Ghulam, Hélène Loiselle, Mathilde Boissel, Emmanuelle Durand, Sylvia Franc, Julie Kerr-Conte, Julie Maillet, Morgane Baron, Marlène Huyvaert, Amélie Bonnefond, Raphaël Boutry, J. Philippe, Jérémy Thomas, Guillaume Charpentier, Claire Lévy-Marchal, Michel Marre, Mehdi Derhourhi, Aurélie Dechaume, Emmanuel Vaillant, B. Balkau, Stefan Gaget, Raphael Scharfmann, Jacques Weill, Mickaël Canouil
المساهمون: Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (EGENODIA (GI3M)), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre d'études et de recherches pour l'intensification du traitement du diabète (CERITD), Centre Hospitalier Sud Francilien, Association Fleurbaix Laventie Ville Santé (FLVS), Centre d'Investigation Clinique - Epidemiologie Clinique/essais Cliniques Hopital Robert Debre, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service d'endocrinologie pédiatrique [CHU Lille], Hôpital Jeanne de Flandre [Lille]-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Fondation ILDYS (ILDYS), Recherche translationnelle sur le diabète - U 1190 (RTD), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot, Sorbonne Paris Cité, Paris, France, Université Paris Diderot - Paris 7 (UPD7), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), AP-HP. Université Paris Saclay, Clinique Ambroise Paré [Centres Médico-Chirurgicaux Ambroise Pré, Pierre Cherest, Hartmann], Imperial College London, This work was supported by grants from the French-speaking Society of Diabetes (Société Française du Diabète) to A.B., from the European Foundation for the Study of Diabetes/Lilly (to A.B.), from the French National Research Agency (ANR-10-LABX-46 (European Genomics Institute for Diabetes) and ANR-10-EQPX-07-01 (LIGAN-PM) to P.F.), from the European Research Council (ERC GEPIDIAB-294785 to P.F. and ERC Reg-Seq-715575 to A.B.), from FEDER (to P.F.) and from the ‘Région Nord Pas-de-Calais’ (to P.F.). A.B. was supported by Inserm., ANR-10-EQPX-0007,LIGAN PM,Plate forme Lilloise de séquençage du génome humain pour une médecine personnalisée(2010), European Project: 294785,EC:FP7:ERC,ERC-2011-ADG_20110310,GEPIDIAB(2012), Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (GI3M), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Laboratoire de Biochimie et Hormonologie [CHRU LIlle] (Centre de Biologie Pathologie), Service de Diabétologie [Orsay, Corbeil-Essonnes], Université Paris-Sud - Paris 11 (UP11)-Hôpital Sud Francilien Corbeil Essonne, Centre d'Etudes et de Recherches pour l'Intensification du Traitement du Diabète (CERITD), Association 'Fleurbaix Laventie Ville Santé' (FLVS), Association Fleurbaix Laventie Ville Santé, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Ildys Foundation [Roscoff, France], Départment de Diabétologie, Endocrinologie et Nutrition [AP-HP Hôpital Bichat], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-DHU FIRE Centre de compétence des maladies pulmonaires rares, École pratique des hautes études (EPHE), UFR de Médecine - Sorbonne Paris Cité (Université Paris Diderot - Paris 7 - UPD7), Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), CMC Ambroise Paré [Neuilly-sur-Seine, France], Department of Metabolism [London, UK] (Section of Genomics of Common Disease), Bonnefond, Amelie, Plate forme Lilloise de séquençage du génome humain pour une médecine personnalisée - - LIGAN PM2010 - ANR-10-EQPX-0007 - EQPX - VALID, Genetics and epigenetics of Type 2 Diabetes physiology - GEPIDIAB - - EC:FP7:ERC2012-11-01 - 2017-10-31 - 294785 - VALID
المصدر: Nature Medicine
Nature Medicine, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
Nature medicine
Nature Medicine, Nature Publishing Group, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩مصطلحات موضوعية: 0301 basic medicine, Male, MESH: Hypertension / complications, MESH: Hypertension / pathology, [SDV.GEN] Life Sciences [q-bio]/Genetics, 0302 clinical medicine, Loss of Function Mutation, Risk Factors, MESH: Obesity / complications, Receptor, Child, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, MESH: Obesity / metabolism, MESH: Loss of Function Mutation / genetics, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, MESH: Receptor, Melanocortin, Type 4 / genetics, General Medicine, Middle Aged, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Metabolic effects, Hypertension, Receptor, Melanocortin, Type 4, Female, Melanocortin, MESH: Hyperglycemia / pathology, Adult, medicine.medical_specialty, Adolescent, MESH: Energy Metabolism / genetics, Obesity risk, Hyperphagia, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Islets of Langerhans, Young Adult, MESH: Genetic Predisposition to Disease, Internal medicine, medicine, Humans, MESH: Adaptor Proteins, Signal Transducing / genetics, Genetic Predisposition to Disease, Obesity, Loss function, Adaptor Proteins, Signal Transducing, MESH: Hyperphagia / pathology, [SDV.GEN]Life Sciences [q-bio]/Genetics, MESH: Humans, business.industry, Pancreatic islets, Energy control, medicine.disease, 030104 developmental biology, Blood pressure, Endocrinology, Hyperglycemia, MESH: Obesity / pathology, business, Energy Metabolism, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, MESH: Hyperphagia / complications
وصف الملف: application/pdf
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المؤلفون: Eric G. Krause, Annette D. de Kloet, Thomas Unger, Ulrike Muscha Steckelings, Colin Sumners
المساهمون: Bedrijfsbureau CD, RS: CARIM - R3 - Vascular biology
المصدر: Current Opinion in Pharmacology, 21, 115-121. Elsevier BV
Sumners, C, de Kloet, A D, Krause, E G, Unger, T & Steckelings, U M 2015, ' Angiotensin type 2 receptors : blood pressure regulation and end organ damage ', Current Opinion in Pharmacology, vol. 21, no. April, pp. 115-121 . https://doi.org/10.1016/j.coph.2015.01.004مصطلحات موضوعية: medicine.medical_specialty, End organ damage, Blood Pressure, Stimulation, Kidney, Receptor, Angiotensin, Type 2, Article, Kidney/pathology, Hypertension/pathology, Internal medicine, Drug Discovery, Renin–angiotensin system, medicine, Animals, Brain/pathology, Receptor, Blood Pressure/physiology, Pharmacology, biology, business.industry, Brain, Angiotensin-converting enzyme, medicine.disease, Receptor, Angiotensin, Type 2/agonists, Blockade, Blood pressure, Endocrinology, medicine.anatomical_structure, Hypertension, biology.protein, business
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المؤلفون: M. Niederberger, Bernard Waeber, Daniel Hayoz, B. Rutschmann, H. R. Brunner, C. Y. Genton
المصدر: European Heart Journal, vol. 14 Suppl C, pp. 10-3
مصطلحات موضوعية: Male, medicine.medical_specialty, Captopril, Vasodilator Agents, External carotid artery, Rats, Inbred WKY, Internal medicine, medicine.artery, Rats, Inbred SHR, medicine, Animals, Common carotid artery, cardiovascular diseases, Animals Captopril/pharmacology Carotid Artery, External/drug effects/pathology/*physiopathology Compliance/drug effects Hydralazine/pharmacology Hypertension/pathology/*physiopathology Male Rats Rats, Inbred SHR Rats, Inbred WKY Vasodilator Agents/pharmacology, business.industry, Hydralazine, Rats, Blood pressure, Dilator, ACE inhibitor, Carotid Artery, External, Hypertension, Cardiology, cardiovascular system, Halothane, Cardiology and Cardiovascular Medicine, business, medicine.drug, Compliance, circulatory and respiratory physiology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3eca69e91c14a4e54579cf6e8d1c135
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المؤلفون: Louise A. Donnelly, Zoltán Kutalik, Ewan R. Pearson, Marcus A. Tuke, Timothy M. Frayling, Aaron McDaid, Samuel E. Jones, Patricia B. Munroe, Andrew R. Wood, Lynne J. Hocking, Archie Campbell, Michael P. Bancks, Jessica Tyrrell, Anna Murray, Michael N. Weedon, Robin N Beaumont, Rachel M. Freathy, Caroline Hayward, Katherine S. Ruth, James S. Pankow, Hanieh Yaghootkar, Colin N. A. Palmer
المصدر: Human molecular genetics, vol. 26, no. 5, pp. 1018-1030
Yaghootkar, H, Bancks, M P, Jones, S E, McDaid, A, Beaumont, R, Donnelly, L, Wood, A R, Campbell, A, Tyrrell, J, Hocking, L J, Tuke, M A, Ruth, K S, Pearson, E R, Murray, A, Freathy, R M, Munroe, P B, Hayward, C, Palmer, C, Weedon, M N, Pankow, J S, Frayling, T M & Kutalik, Z 2017, ' Quantifying the extent to which index event biases influence large genetic association studies ', Human Molecular Genetics, vol. 26, no. 5 . https://doi.org/10.1093/hmg/ddw433مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, Index (economics), Diabetes risk, Genotype, Population, Library science, Disease, Type 2 diabetes, Biology, Polymorphism, Single Nucleotide, Body Mass Index, 03 medical and health sciences, Alleles, Blood Glucose/genetics, Diabetes Mellitus, Type 2/genetics, Genetic Association Studies, Genetic Predisposition to Disease, Humans, Hypertension/genetics, Hypertension/pathology, Obesity/genetics, Genetics, Medicine, Obesity, Allele, Aric study, education, Molecular Biology, Genetics (clinical), Genetic association, Government, education.field_of_study, business.industry, European research, Association Studies Articles, General Medicine, Medical research, medicine.disease, Biobank, NASA Chief Scientist, Atherosclerosis Risk in Communities, 030104 developmental biology, Diabetes Mellitus, Type 2, Hypertension, Trait, business, TCF7L2, Demography
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8122a5a41d4f4076fae50c81a1f353e3
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المؤلفون: Timo A. Lakka, Kathleen Stirrups, Jean Ferrières, Ying Wu, Gulum Kosova, Toby Johnson, Heather M. Stringham, Bruce M. Psaty, Bruna Gigante, Göran Hallmans, Cornelia M. van Duijn, Kae Woei Liang, Niclas Eriksson, N. William Rayner, Lynda M. Rose, Stavroula Kanoni, Xueling Sim, Evangelos Evangelou, Philippe Froguel, Michel Burnier, Andrew P. Morris, Olle Melander, Martin Farrall, Albert V. Smith, Brendan J. Keating, Thomas Illig, Johan Sundström, Dorret I. Boomsma, Kate Witkowska, Ellen M. Schmidt, Aki S. Havulinna, Ann-Kristin Petersen, Paul F. O'Reilly, Young Jin Kim, Kari Kuulasmaa, Tom Wilsgaard, John D. Eicher, Marcus E. Kleber, Francis S. Collins, Rona J. Strawbridge, Ronald M. Krauss, Fotios Drenos, Stuart K. Kim, Ken K. Ong, Pascal Bovet, Danish Saleheen, Jaspal S. Kooner, Karl-Heinz Herzig, Tien Yin Wong, Benjamin F. Voight, Stefania Bandinelli, Stéphane Lobbens, Colin A. McKenzie, Jing Hua Zhao, Terrence Forrester, Louise A. Donnelly, Alice Stanton, Jean Dallongeville, Kirill V. Tarasov, Narisu Narisu, Jürgen Gräßler, Luigi Ferrucci, Peter S. Sever, Paul Elliott, Tune H. Pers, Andrew J. Smith, Tomas Axelsson, Young Ah Shin, Nora Franceschini, James F. Wilson, Vilmundur Gudnason, Kati Kristiansson, Andrew A. Hicks, Kent D. Taylor, Genovefa Kolovou, Andrew D. Morris, André G. Uitterlinden, Serena Sanna, Xiuqing Guo, Honghuang Lin, Aravinda Chakravarti, Wayne Huey-Herng Sheu, Panos Deloukas, Linda S. Adair, Diana Kuh, Murielle Bochud, Eric Boerwinkle, Inger Njølstad, Meena Kumari, Norman Klopp, Leo-Pekka Lyytikäinen, Steven C. Hunt, Weihua Zhang, Tõnu Esko, Pierre Meneton, Markus Perola, Erik P A Van Iperen, Georg Ehret, Veikko Salomaa, Lars Lind, Zoltán Kutalik, Cristiano Fava, Caroline Hayward, Hugh S. Markus, Teresa Ferreira, Stefan R. Bornstein, Vasyl Pihur, Patricia B. Munroe, Anne U. Jackson, Eirini Marouli, Gabriele Müller, Damiano Baldassarre, Jacques E. Rossouw, Dan E. Arking, Maija Hassinen, Nicholas J. Wareham, Robert Roberts, Daniel I. Chasman, I. Shou Chang, Sylvain Sebert, Tove Fall, Roby Joehanes, Patrik K. E. Magnusson, John C. Chambers, Peter Vollenweider, Wen Jane Lee, Dmitry Shungin, Mathias Gorski, Christopher Newton-Cheh, Anders Franco-Cereceda, Ching-Yu Cheng, Yun Kyoung Kim, Ruth J. F. Loos, Lude Franke, Karen L. Mohlke, Yii-Der Ida Chen, Carlos Iribarren, Martina Müller-Nurasyid, Alexander Teumer, Andrew D. Johnson, Antonella Mulas, Ulf Gyllensten, Martin D. Tobin, George Dedoussis, Rainford J. Wilks, Joshua C. Bis, Beverley Balkau, Jie Yao, Frida Renström, Themistocles L. Assimes, Morris Brown, Inês Barroso, Hyun Min Kang, Loic Yengo, Mika Kähönen, Christopher J. Groves, Kirsti Kvaløy, Rainer Rauramaa, Heribert Schunkert, Satu Männistö, Marjo-Riitta Järvelin, Nancy L. Pedersen, Karl Gertow, Rick Jansen, Thomas Quertermous, Jarmo Virtamo, Lazaros Lataniotis, Serge Hercberg, Paul M. Ridker, Osorio Meirelles, Jostein Holmen, Phil Howard, G. Kees Hovingh, Jeanette Erdmann, Jong-Young Lee, Peter Schwarz, Ramaiah Nagaraja, Elizabeth Theusch, Wei Zhao, Sonia Shah, Chao A. Hsiung, Santhi K. Ganesh, Richard S. Cooper, John M. C. Connell, Jian'an Luan, Graciela E. Delgado, Eric Kim, Daniel Levy, Li Lin, Jerome I. Rotter, Andres Metspalu, Nabila Bouatia-Naji, Christopher J. O'Donnell, Roberto Elosua, Andrew Wong, Alanna C. Morrison, Juha Saltevo, Michael R. Barnes, Alan B. Weder, Kay-Tee Khaw, Leena Moilanen, Peter S. Chines, Claudia Langenberg, Marika Kaakinen, Asif Rasheed, Annette Peters, Angela Döring, Alena Stančáková, Richard A. Jensen, Jaana Lindström, Alison H. Goodall, Toshiko Tanaka, Loukianos S. Rallidis, Dabeeru C. Rao, Ann-Christine Syvänen, Alun Evans, Brenda W.J.H. Penninx, Sarah Edkins, Xiaohui Li, Neil Poulter, Jouko Saramies, Ulf de Faire, Walter Palmas, Jaakko Tuomilehto, Louise V. Wain, Cristina Menni, Stephen Bevan, Maria X. Sosa, Nanette R. Lee, Anuj Goel, Germaine C. Verwoert, Kjell Nikus, Helen R. Warren, May E. Montasser, Ren-Hua Chung, Francesco Gianfagna, Kristian Hveem, Rainer Rettig, Unnur Thorsteinsdottir, Lori L. Bonnycastle, Tim D. Spector, Paul W. Franks, Bamidele O. Tayo, Ilja M. Nolte, John Danesh, E. Shyong Tai, Mika Kivimäki, Devin Absher, Oddgeir L. Holmen, Per Eriksson, Pirjo Komulainen, Peter P. Pramstaller, Cameron D. Palmer, He Gao, Elena Tremoli, H.-Erich Wichmann, Myriam Fornage, Gyda Bjornsdottir, Afshin Parsa, Anders Hamsten, Terho Lehtimäki, Lasse Folkersen, Janine F. Felix, Anna F. Dominiczak, Hinco J. Gierman, Edward G. Lakatta, Alex S. F. Doney, Erik Ingelsson, Colin N. A. Palmer, Najaf Amin, Hugh Watkins, Johanna Kuusisto, Vladan Mijatovic, Mark I. McCarthy, Joel N. Hirschhorn, Winfried März, Nilesh J. Samani, Stefan Enroth, Mark J. Caulfield, Gudmar Thorleifsson, Tsun-Po Yang, François Mach, Cristen J. Willer, Claudia P. Cabrera, Aline Wagner, Michael Boehnke, Elias Salfati, Sekar Kathiresan, Ramachandran S. Vasan, Franco Giulianini, Harm-Jan Westra, Harold Snieder, Mark O. Goodarzi, M. Arfan Ikram, Fred Paccaud, Johannes H. Smit, Anna-Liisa Hartikainen, Xiaofeng Zhu, Markku Laakso, Ahmad Vaez, Albert Hofman, Amy J. Swift, Maria Hughes, I. Te Lee, Aroon D. Hingorani, Matti Uusitupa, Oscar H. Franco, Kenneth Rice, Veronique Vitart, Ross M. Fraser, Jouke-Jan Hottenga, Kari Stefansson, Dhananjay Vaidya
المساهمون: Johns Hopkins University, School of Medicine, Hôpitaux Universitaires de Genève (HUG), Saw Swee Hock School of Public Health, National University of Singapore (NUS), The Wellcome Trust Centre for Human Genetics [Oxford], University of Oxford [Oxford], Brigham and Women's Hospital [Boston], Harvard Medical School [Boston] (HMS), Department of Biostatistics, University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System, University of Michigan System, Department of Computational Medicine and Bioinformatics (DCM&B), Queen Mary University of London (QMUL), GlaxoSmithKline, Glaxo Smith Kline, deCODE genetics [Reykjavik], University of Cambridge [UK] (CAM), University of Dundee, German Research Center for Environmental Health - Helmholtz Center München (GmbH), Karolinska University Hospital [Stockholm], Umea University Hospital, Lund University [Lund], Queen's University [Belfast] (QUB), National Institutes of Health, Department of Genomics of Common Disease, Imperial College London, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Descartes - Paris 5 (UPD5), National Institute of Health and Welfare, Institute for Molecular Medicine Finland (FIMM), University College London Hospitals (UCLH), University Hospital of Heidelberg, Harbor UCLA Medical Center [Torrance, Ca.], University of Tampere, University of Verona (UNIVR), Uppsala University Hospital, Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet [Stockholm], Stanford University School of Medicine [CA, USA], Medical School University of Athens, Partenaires INRAE, Children's Hospital Oakland Research Institute, Boston Children's Hospital, Broad Institute of Harvard and MIT, University of Copenhagen = Københavns Universitet (KU), Statens Serum Institut [Copenhagen], Framingham Heart Dis Epidemiol Study, Department of Psychiatry, VU University Medical Center [Amsterdam], National Heart, Lung and Blood Institute, Osong Health Technology Administration Complex, University of Pennsylvania, Department of Genetics, University of North Carolina at Chapel Hill (UNC), Loyola University [Chicago], Centre Hospitalier Universitaire Vaudois (CHUV), Hudson Alpha Institute for Biotechnology, Erasmus University Rotterdam, Department of Medical Sciences, Uppsala University, Università degli Studi di Milano [Milano] (UNIMI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Université Paris-Sud - Paris 11 (UP11), Azienda Sanitaria Firenze, Wellcome Trust Genome Campus, The Wellcome Trust Sanger Institute [Cambridge], University of Lincoln, University of Washington [Seattle], Amgen Inc., The University of Texas Health Science Center at Houston (UTHealth), VU University Amsterdam, University of Dresden Medical School, Université de Lausanne (UNIL), Healthcare NHS Trust, National Health Research Institutes, National University Health System [Singapore] (NUHS), Duke-NUS Medical School [Singapore], Singapore Eye Research Institute [Singapore] (SERI), National Human Genome Research Institute (NHGRI), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Recherche Agronomique (INRA), Psychiatry, Amsterdam Neuroscience - Complex Trait Genetics, Radiology and nuclear medicine, EMGO - Mental health, Lin, Li, Mach, François, ProdInra, Migration, University of Oxford, Università degli studi di Verona = University of Verona (UNIVR), University of Copenhagen = Københavns Universitet (UCPH), Università degli Studi di Milano = University of Milan (UNIMI), Vrije Universiteit Amsterdam [Amsterdam] (VU), Université de Lausanne = University of Lausanne (UNIL), Institut National de la Recherche Agronomique (INRA)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'Informatique Médicale et Ingénierie des Connaissances en e-Santé (LIMICS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Sorbonne Paris Nord, Vrije universiteit = Free university of Amsterdam [Amsterdam] (VU), EMGO+ - Lifestyle, Overweight and Diabetes, Biological Psychology, APH - Amsterdam Public Health, Epidemiology and Data Science, Graduate School, Other departments, ACS - Amsterdam Cardiovascular Sciences, Vascular Medicine, Luan, Jian'an [0000-0003-3137-6337], Barroso, Ines [0000-0001-5800-4520], Danesh, John [0000-0003-1158-6791], Khaw, Kay-Tee [0000-0002-8802-2903], Markus, Hugh [0000-0002-9794-5996], Ong, Kenneth [0000-0003-4689-7530], Johnson, Kathleen [0000-0002-6823-3252], Wareham, Nicholas [0000-0003-1422-2993], Zhao, Jing Hua [0000-0003-4930-3582], Langenberg, Claudia [0000-0002-5017-7344], Apollo - University of Cambridge Repository, Life Course Epidemiology (LCE), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Stem Cell Aging Leukemia and Lymphoma (SALL), CHARGE-EchoGen Consortium, CHARGE-HF Consortium, Wellcome Trust Case Control Consortium, Medical Microbiology & Infectious Diseases, Epidemiology, Neurology, Radiology & Nuclear Medicine, Internal Medicine, Clinical Genetics, Biochemistry, National Institute for Health Research, Medical Research Council (MRC)
المصدر: Nature Genetics
Nature Genetics, Nature Publishing Group, 2016, 48 (10), pp.1171-1184. ⟨10.1038/ng.3667⟩
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Nature genetics, vol 48, iss 10
Nature Genetics, 48(10), 1171-1184. Nature Publishing Group
Nature Genetics, Vol. 48, No 10 (2016) pp. 1171-1184
Nature Genetics, 2016, 48 (10), pp.1171-1184. ⟨10.1038/ng.3667⟩
Ehret, G B, Ferreira, T, Chasman, D I, Jackson, A U, Schmidt, E M, Johnson, T, Thorleifsson, G, Luan, J, Donnelly, L A, Kanoni, S, Jansen, R, Boomsma, D I, Hottenga, J J, Penninx, B W J H, van Duijn, C M, Wichmann, H E, Palmer, C N A, Stefansson, K, Ridker, P M, Loos, R J F, Chakravarti, A, Deloukas, P, Morris, A P, Newton-Cheh, C & Munroe, P B 2016, ' The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals ', Nature Genetics, vol. 48, no. 10, pp. 1171-1184 . https://doi.org/10.1038/ng.3667
2016, ' The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals ', Nature Genetics, vol. 48, no. 10, pp. 1171-1184 . https://doi.org/10.1038/ng.3667
Nature genetics, 48(10), 1171-1184. Nature Publishing Group
NATURE GENETICS
Ehret, G B, Ferreira, T, Chasman, D I, Jackson, A U, Schmidt, E M, Johnson, T, Thorleifsson, G, Luan, J, Donnelly, L A, Kanoni, S, Petersen, A-K, Pihurl, V, Strawbridge, R J, Shungin, D, Hughes, M F, Meirelles, O, Kaakinen, M, Bouatia-Naji, N, Kristiansson, K, Shah, S, Kleber, M E, Guo, X, Lyytikainen, L-P, Fava, C, Eriksson, N, Nolte, I M, Magnusson, P K, Salfati, E L, Rallidis, L S, Theusch, E, Smith, A J P, Folkersen, L, Witkowska, K, Pers, T H, Joehanes, R, Kim, S K, Lataniotis, L, Jansen, R, Johnson, A D, Warren, H, Kim, Y J, Zhao, W, Wu, Y, Tayo, B O, Bochud, M, Absher, D, Adair, L S, Amin, N, Arkingl, D E, Axelsson, T, Baldassarre, D, Balkau, B, Bandinelli, S, Barnes, M R, Barroso, I, Bevan, S, Bis, J C, Bjornsdottir, G, Boehnke, M, Boerwinkle, E, Bonnycastle, L L, Boomsma, D I, Bornstein, S R, Brown, M J, Burnier, M, Cabrera, C P, Chambers, J C, Chang, I-S, Cheng, C-Y, Chines, P S, Chung, R-H, Collins, F S, Connell, J M, Doring, A, Dallongeville, J, Danesh, J, de Faire, U, Delgado, G, Dominiczak, A F, Doney, A S F, Drenos, F, Edkins, S, Eicher, J D, Elosua, R, Enroth, S, Erdmann, J, Eriksson, P, Esko, T, Evangelou, E, Evans, A, Fai, T, Farra, M, Felixl, J F, Ferrieres, J, Ferrucci, L, Fornage, M, Forrester, T, Franceschinil, N, Franco, O H, Franco-Cereceda, A, Fraser, R M, Ganesh, S K, Gao, H, Gertow, K, Gianfagna, F, Gigante, B, Giulianini, F, Goe, A, Goodall, A H, Goodarzi, M, Gorski, M, Grassler, J, Groves, C J, Gudnason, V, Gyllensten, U, Hallmans, G, Hartikainen, A-L, Hassinen, M, Havulinna, A S, Hayward, C, Hercberg, S, Herzig, K-H, Hicks, A A, Hingorani, A D, Hirschhorn, J N, Hofmanl, A, Holmen, J, Holmen, O L, Hottenga, J-J, Howard, P, Hsiung, C A, Hunt, S C, Ikram, M A, Illig, T, Iribarren, C, Jensen, R A, Kahonen, M, Kang, H M, Kathiresan, S, Keating, B J, Khaw, K-T, Kim, Y K, Kim, E, Kivimaki, M, Klopp, N, Kolovou, G, Komulainen, P, Kooner, J S, Kosova, G, Krauss, R M, Kuh, D, Kutalik, Z, Kuusisto, J, Kvaloy, K, Lakka, T A, Lee, N R, Lee, I-T, Lee, W-J, Levy, D, Li, X, Liang, K-W, Lin, H, Lin, L, Lindstrom, J, Lobbens, S, Mannisto, S, Muller, G, Muller-Nurasyid, M, Mach, F, Markus, H S, Marouli, E, McCarthy, M I, McKenzie, C A, Meneton, P, Menni, C, Metspalu, A, Mijatovic, V, Moilanen, L, Montasser, M E, Morris, A D, Morrison, A C, Mulas, A, Nagaraja, R, Narisu, N, Nikus, K, O'Donnell, C J, O'Reilly, P F, Ong, K K, Paccaud, F, Palmer, C D, Parsa, A, Pedersen, N L, Penninx, B W, Perola, M, Peters, A, Poulter, N, Pramstaller, P P, Psaty, B M, Quertermous, T, Rao, D C, Rasheed, A, Rayner, N W, Renstrom, F, Rettig, R, Rice, K M, Roberts, R, Rose, L M, Rossouw, J, Samani, N J, Sanna, S, Saramies, J, Schunkert, H, Sebert, S, Sheu, W H-H, Shin, Y-A, Sim, X, Smit, J H, Smith, A V, Sosa, M X, Spector, T D, Stancakova, A, Stanton, A V, Stirrups, K E, Stringham, H M, Sundstrom, J, Swift, A J, Syvanen, A-C, Tai, E-S, Tanaka, T, Tarasov, K V, Teumer, A, Thorsteinsdottir, U, Tobin, M D, Tremoli, E, Uitterlinden, A G, Uusitupa, M, Vaez, A, Vaidya, D, van Duijn, C M, van Iperen, E P A, Vasan, R S, Verwoert, G C, Virtamo, J, Vitart, V, Voight, B F, Vollenweider, P, Wagner, A, Wain, L V, Wareham, N J, Watldns, H, Weder, A B, Westra, H J, Wilks, R, Wilsgaard, T, Wilson, J F, Wong, T Y, Yang, T-P, Yao, J, Yengo, L, Zhang, W, Zhao, J H, Zhu, X, Bovet, P, Cooper, R S, Mohlke, K L, Saleheen, D, Lee, J-Y, Elliott, P, Gierman, H J, Willer, C J, Franke, L, Hovingh, G K, Taylor, K D, Dedoussis, G, Sever, P, Wong, A, Lind, L, Assimes, T L, Njolstad, I, Schwarz, P E H, Langenberg, C, Snieder, H, Caulfield, M J, Melander, E, Laakso, M, Saltevo, J, Rauramaa, R, Tuomilehto, J, Ingelsson, E, Lehtimaki, T, Hveem, K, Palmas, W, Marz, W, Kumar, M, Salomaa, V, Chen, Y-D I, Rotter, J I, Froguel, P, Jarvelin, M-R, Lakatta, E G, Kuulasmaa, K, Franks, P W, Hamsten, A, Wichmann, H-E, Palmer, C N A, Stefansson, K, Ridker, P M, Loos, R J F, Chalcravarti, A, Deloukas, P, Morris, A P, Newton-Cheh, C & Munroe, P B 2016, ' The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals ', Nature Genetics, vol. 48, no. 10, pp. 1171-1184 . https://doi.org/10.1038/ng.3667
Nature genetics, vol. 48, no. 10, pp. 1171-1184مصطلحات موضوعية: 0301 basic medicine, Netherlands Twin Register (NTR), CHROMATIN, [SDV]Life Sciences [q-bio], LOCI, Genome-wide association study, Blood Pressure, SUSCEPTIBILITY, Bioinformatics, Cardiovascular, Genome-wide association studies, Medical and Health Sciences, single nucleotide polymorphism, CHARGE-EchoGen consortium, GWAS, 2.1 Biological and endogenous factors, Aetiology, Cells, Cultured, African Continental Ancestry Group, Genetics & Heredity, Genetics, ddc:616, Kidney, Framingham Risk Score, Cultured, COMMON VARIANTS, 11 Medical And Health Sciences, Single Nucleotide, Biological Sciences, African Continental Ancestry Group/genetics, Asian Continental Ancestry Group/genetics, Blood Pressure/genetics, Genome-Wide Association Study, Humans, Hypertension/genetics, Hypertension/pathology, Microarray Analysis, Polymorphism, Single Nucleotide, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Hypertension/genetics/pathology, Hypertension, Medical genetics, Wellcome Trust Case Control Consortium, Life Sciences & Biomedicine, TRAITS, Biotechnology, Asian Continental Ancestry Group, medicine.medical_specialty, CHARGE-EchoGen Consortium, Cells, Black People, BIOLOGY, Single-nucleotide polymorphism, Biology, Blood pressure, hypertension, genetics, single nucleotide polymorphism, GWAS, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Asian People, medicine, Polymorphism, GENOME-WIDE ASSOCIATION, CELL-TYPES, METAANALYSIS, Genetic association, Science & Technology, CHARGE-HF consortium, 06 Biological Sciences, Genetic architecture, 030104 developmental biology, Blood pressure, CHARGE-HF Consortium, ARTERIAL-HYPERTENSION, Developmental Biology
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
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المؤلفون: Nilsson, Peter
المصدر: Vascular Health and Risk Management. 4(3):547-552
مصطلحات موضوعية: Telomere: pathology, Smoking: physiopathology, Hypertension: physiopathology, Hypertension: pathology, Type 2: physiopathology, Diabetes Mellitus, Blood Vessels: pathology, Type 2: pathology, Medicin och hälsovetenskap, Klinisk medicin, Kardiologi, Medical and Health Sciences, Clinical Medicine, Cardiac and Cardiovascular Systems
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المصدر: Circulation Research, Vol. 104, No 1 (2009) pp. 104-12
مصطلحات موضوعية: Vascular smooth muscle, Thiazepines, Physiology, Mitochondrion, Clonazepam, Muscle, Smooth, Vascular, Adenosine Triphosphate, Sarcoplasmic Reticulum/metabolism, Hypertension/pathology, Mitochondria, Muscle/physiology, Myocyte, Membrane Proteins/genetics/physiology, Aorta, Recombinant Fusion Proteins/physiology, Purinergic receptor, Thiourea, musculoskeletal system, Sarcoplasmic Reticulum, Muscle, Smooth, Vascular/cytology, Hypertension, Cardiology and Cardiovascular Medicine, Thiourea/analogs & derivatives/pharmacology, Myocytes, Smooth Muscle/metabolism/ultrastructure, Sodium-Calcium Exchanger/drug effects/metabolism, Thiazepines/pharmacology, medicine.medical_specialty, Calcium/metabolism, Calcium Signaling/drug effects/physiology, Recombinant Fusion Proteins, Myocytes, Smooth Muscle, chemistry.chemical_element, Calcium, Biology, Mitochondrial Proteins/genetics/physiology, Sodium-Calcium Exchanger, Clonazepam/analogs & derivatives/pharmacology, Mitochondrial Proteins, Internal medicine, medicine, Animals, Calcium Signaling, ddc:612, Calcium metabolism, Cell Membrane/metabolism, Endoplasmic reticulum, Cell Membrane, Sodium, Membrane Proteins, Cell Compartmentation, Mitochondria, Muscle, Rats, Cytosol, Sodium/metabolism, Endocrinology, chemistry, Biophysics, Adenosine Triphosphate/pharmacology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acc8f9c5e8fbef329c74edfe1c6afb1
https://doi.org/10.1161/circresaha.108.180612
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