المؤلفون: Deligeorgopoulou M; Neonatal Intensive Care Unit, School of Medicine, University of Ioannina, Ioannina, Greece., Kosmeri C; Department of Pediatrics, University Hospital of Ioannina, Ioannina, Greece., Giapros V; Neonatal Intensive Care Unit, School of Medicine, University of Ioannina, Ioannina, Greece., Balomenou F; Neonatal Intensive Care Unit, School of Medicine, University of Ioannina, Ioannina, Greece., Baltogianni M; Neonatal Intensive Care Unit, School of Medicine, University of Ioannina, Ioannina, Greece., Serbis A; Department of Pediatrics, University Hospital of Ioannina, Ioannina, Greece.

المصدر: Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2024 Jun; Vol. 113 (6), pp. 1221-1227. Date of Electronic Publication: 2024 Jan 10.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: Norway NLM ID: 9205968 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1651-2227 (Electronic) Linking ISSN: 08035253 NLM ISO Abbreviation: Acta Paediatr Subsets: MEDLINE

مواضيع طبية MeSH: Thyroid Function Tests* , Neonatal Screening*/methods , Congenital Hypothyroidism*/diagnosis, Humans ; Infant, Newborn ; Female ; Pregnancy ; Pregnancy Complications/diagnosis ; Hypothyroidism/diagnosis

المؤلفون: Korkut S; Department of Pediatrics, Division of Neonatology, Ankara City Hospital, University of Health Sciences, Ankara, Türkiye., Çaylan N; Department of Child and Adolescents Health, Ministry of Health, General Directorate of Public Health, Ankara, Türkiye., Özgü-Erdinç AS; Department of Obstetrics and Gynecology, Ankara City Hospital, University of Health Sciences, Ankara, Türkiye., Akın MŞ; Department of Pediatrics, Division of Neonatology, Ankara City Hospital, University of Health Sciences, Ankara, Türkiye., Ceyhan M; Department of Obstetrics and Gynecology, Ankara City Hospital, University of Health Sciences, Ankara, Türkiye., Kara F; Ministry of Health, General Directorate of Public Health, Ankara, Türkiye., Tezel B; Department of Child and Adolescents Health, Ministry of Health, General Directorate of Public Health, Ankara, Türkiye., Oğuz ŞS; Department of Pediatrics, Division of Neonatology, Ankara City Hospital, University of Health Sciences, Ankara, Türkiye.

المصدر: American journal of perinatology [Am J Perinatol] 2024 May; Vol. 41 (S 01), pp. e30-e36. Date of Electronic Publication: 2022 Apr 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Thieme-Stratton Country of Publication: United States NLM ID: 8405212 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-8785 (Electronic) Linking ISSN: 07351631 NLM ISO Abbreviation: Am J Perinatol Subsets: MEDLINE

مواضيع طبية MeSH: Congenital Hypothyroidism*/diagnosis , Congenital Hypothyroidism*/blood , Congenital Hypothyroidism*/epidemiology , Thyrotropin*/blood , Neonatal Screening* , Thyroid Function Tests* , Pregnancy Complications*, Humans ; Female ; Retrospective Studies ; Pregnancy ; Infant, Newborn ; Adult ; Hypothyroidism ; Gestational Age ; Infant, Low Birth Weight

المؤلفون: Rovet JF; Department of Paediatrics, University of Toronto, Toronto, ON M5G1X8, Canada.; Neurosciences and Mental Health Program, The Hospital for Sick Children, Toronto, ON M5G0A4, Canada.

المصدر: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2024 Sep 16; Vol. 109 (10), pp. e1950-e1954.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Hypothyroidism*/complications , Hypothyroidism*/pathology , Hippocampus*/pathology , Hippocampus*/diagnostic imaging , Magnetic Resonance Imaging*, Humans ; Animals

المؤلفون: Özer Y; Department of Pediatric Endocrinology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey. yavuzcp@yahoo.com., Anık A; Department of Pediatric Endocrinology, Faculty of Medicine, Aydın Adnan Menderes University, Aydın, Turkey., Sayılı U; Department of Public Health, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey., Tercan U; Department of Pediatric Endocrinology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey., Deveci Sevim R; Department of Pediatric Endocrinology, Faculty of Medicine, Aydın Adnan Menderes University, Aydın, Turkey., Güneş S; Department of Pediatric Endocrinology, Faculty of Medicine, Aydın Adnan Menderes University, Aydın, Turkey., Buhur Pirimoğlu M; Department of Pediatric Endocrinology, Faculty of Medicine, Bursa Uludağ University, Bursa, Turkey., Elmaoğulları S; Department of Pediatric Endocrinology, University of Health Sciences Turkey, Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Ankara, Turkey., Dündar I; Department of Pediatric Endocrinology, Malatya Education and Research Hospital, Malatya, Turkey., Ökdemir D; Department of Pediatric Endocrinology, Faculty of Medicine, Fırat University, Elazığ, Turkey., Besci Ö; Department of Pediatric Endocrinology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey., Jalilova A; Department of Pediatric Endocrinology, Faculty of Medicine, Ege University, Izmir, Turkey., Çiçek D; Department of Pediatric Endocrinology, Faculty of Medicine, Erciyes University, Kayseri, Turkey., Singin B; Department of Pediatric Endocrinology, Faculty of Medicine, Akdeniz University, Antalya, Turkey., Ulu ŞE; Departments of Pediatric Endocrinology, Ümraniye Training and Research Hospital, Istanbul, Turkey., Turan H; Department of Pediatric Endocrinology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey., Albayrak S; Department of Pediatric Endocrinology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey., Kocabey Sütçü Z; Department of Pediatric Endocrinology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey., Eklioğlu BS; Department of Pediatric Endocrinology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey., Eren E; Department of Pediatric Endocrinology, Faculty of Medicine, Bursa Uludağ University, Bursa, Turkey., Çetinkaya S; Department of Pediatric Endocrinology, University of Health Sciences Turkey, Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Ankara, Turkey., Savaş-Erdeve Ş; Department of Pediatric Endocrinology, University of Health Sciences Turkey, Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Ankara, Turkey., Esen I; Department of Pediatric Endocrinology, Faculty of Medicine, Fırat University, Elazığ, Turkey., Demir K; Department of Pediatric Endocrinology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey., Darcan Ş; Department of Pediatric Endocrinology, Faculty of Medicine, Ege University, Izmir, Turkey., Hatipoğlu N; Department of Pediatric Endocrinology, Faculty of Medicine, Erciyes University, Kayseri, Turkey., Parlak M; Department of Pediatric Endocrinology, Faculty of Medicine, Akdeniz University, Antalya, Turkey., Dursun F; Departments of Pediatric Endocrinology, Ümraniye Training and Research Hospital, Istanbul, Turkey., Şıklar Z; Department of Pediatric Endocrinology, Faculty of Medicine, Ankara University, Ankara, Turkey., Berberoğlu M; Department of Pediatric Endocrinology, Faculty of Medicine, Ankara University, Ankara, Turkey., Keskin M; Department of Pediatric Endocrinology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey., Orbak Z; Department of Pediatric Endocrionology, Faculty of Medicine, Atatürk University, Erzurum, Turkey., Tezel B; Department of Child and Adolescents Health, Ministry of Health, General Directorate of Public Health, Ankara, Turkey., Yürüker E; Department of Child and Adolescents Health, Ministry of Health, General Directorate of Public Health, Ankara, Turkey., Keskinkılıç B; Department of Child and Adolescents Health, Ministry of Health, General Directorate of Public Health, Ankara, Turkey., Kara F; Department of Child and Adolescents Health, Ministry of Health, General Directorate of Public Health, Ankara, Turkey., Erginöz E; Department of Public Health, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey., Darendeliler F; Department of Pediatric Endocrinology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey., Evliyaoğlu O; Department of Pediatric Endocrinology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

المصدر: Journal of endocrinological investigation [J Endocrinol Invest] 2024 Sep; Vol. 47 (9), pp. 2213-2224. Date of Electronic Publication: 2024 Mar 28.

نوع المنشور: Journal Article; Observational Study; Multicenter Study

بيانات الدورية: Publisher: Springer Country of Publication: Italy NLM ID: 7806594 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1720-8386 (Electronic) Linking ISSN: 03914097 NLM ISO Abbreviation: J Endocrinol Invest Subsets: MEDLINE

مواضيع طبية MeSH: Congenital Hypothyroidism*/drug therapy , Congenital Hypothyroidism*/diagnosis , Congenital Hypothyroidism*/blood , Congenital Hypothyroidism*/epidemiology , Thyroxine*/administration & dosage , Thyroxine*/blood , Neonatal Screening*/methods, Humans ; Female ; Retrospective Studies ; Male ; Infant, Newborn ; Turkey/epidemiology ; Infant ; Follow-Up Studies ; Child, Preschool ; Prognosis

المؤلفون: García Pascual L; Servei d'Endocrinologia, Hospital Universitari Mútua de Terrasa, Terrassa, Barcelona, Spain. Electronic address: 23566LGP@comb.cat., Puig-Jové C; Servei d'Endocrinologia, Hospital Universitari Mútua de Terrasa, Terrassa, Barcelona, Spain., Simó-Servat A; Servei d'Endocrinologia, Hospital Universitari Mútua de Terrasa, Terrassa, Barcelona, Spain., García-González L; Servei de Cirurgia General i Aparell Digestiu, Hospital Universitari Arnau de Vilanova, Lleida, Spain.

المصدر: Endocrinologia, diabetes y nutricion [Endocrinol Diabetes Nutr (Engl Ed)] 2024 Aug-Sep; Vol. 71 (7), pp. 298-307. Date of Electronic Publication: 2024 Aug 02.

نوع المنشور: Journal Article; Observational Study; Comparative Study

بيانات الدورية: Publisher: Country of Publication: Spain NLM ID: 101717565 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2530-0180 (Electronic) Linking ISSN: 25300180 NLM ISO Abbreviation: Endocrinol Diabetes Nutr (Engl Ed) Subsets: MEDLINE

مواضيع طبية MeSH: Hypothyroidism*/epidemiology , Hypothyroidism*/blood , Hypothyroidism*/etiology , Thyroidectomy* , Goiter, Nodular*/surgery , Goiter, Nodular*/epidemiology , Hyperthyroidism*/epidemiology , Hyperthyroidism*/blood , Hyperthyroidism*/surgery, Humans ; Cross-Sectional Studies ; Female ; Male ; Retrospective Studies ; Middle Aged ; Prevalence ; Adult ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/blood ; Aged ; Biomarkers/blood ; Thyrotropin/blood

المؤلفون: Barasch E; De Matteis Cardiovascular Institute, St. Francis Hospital, The Heart Center/SUNY at Stony Brook, 11537 Roslyn, NY, USA., Gottdiener J; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Buzkova P; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Cappola A; Division of Endocrinology, University of Pennsylvania, Philadelphia, PA 19104, USA., Shah S; Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., DeFilippi C; Division of Cardiology, Inova Health System, Falls Church, VA 22031, USA., Gardin J; Department of Medicine, Division of Cardiology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA., Kizer JR; Cardiology Section, San Francisco Veterans Affairs Health Care System, and Departments of Medicine, Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94121, USA.

المصدر: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2024 Sep 16; Vol. 109 (10), pp. e1847-e1856.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Hyperthyroidism*/complications , Hyperthyroidism*/epidemiology , Hypothyroidism*/complications , Hypothyroidism*/epidemiology , Hypothyroidism*/physiopathology , Biomarkers*/blood, Humans ; Male ; Female ; Aged ; Cross-Sectional Studies ; Aged, 80 and over ; Echocardiography ; Peptide Fragments/blood ; Natriuretic Peptide, Brain/blood ; Heart Diseases/epidemiology ; Heart Diseases/etiology ; Cohort Studies

المؤلفون: Penna GC; Section of Adult and Pediatric Endocrinology, Diabetes & Metabolism, The University of Chicago, Chicago, IL 60637, USA.; Department of Internal Medicine, Universidade Federal e Minas Gerais, Belo Horizonte, MG 31270-901, Brazil., Bensenor IM; Center for Clinical and Epidemiological Research, Hospital Universitário, Universidade de São Paulo, São Paulo, 05508-220, Brazil., Bianco AC; Section of Adult and Pediatric Endocrinology, Diabetes & Metabolism, The University of Chicago, Chicago, IL 60637, USA., Ettleson MD; Section of Adult and Pediatric Endocrinology, Diabetes & Metabolism, The University of Chicago, Chicago, IL 60637, USA.

المصدر: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2024 Sep 16; Vol. 109 (10), pp. 2504-2512.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Thyroxine*/therapeutic use , Thyroxine*/blood , Thyroxine*/administration & dosage , Homeostasis*/drug effects , Hypothyroidism*/drug therapy , Hypothyroidism*/blood, Humans ; Middle Aged ; Female ; Male ; Adult ; Longitudinal Studies ; Aged ; Brazil ; Thyroid Hormones/blood ; Triiodothyronine/blood ; Thyrotropin/blood ; Thyroid Function Tests ; Hormone Replacement Therapy/methods

المؤلفون: Huang CC; Department of Emergency Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Emergency Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; School of Medicine, College of Medicine, National Sun Yat-sen university, Kaohsiung, Taiwan; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address: jasonhuang0803@gmail.com., Chen TH; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan., Ho CH; Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan; Department of Information Management, Southern Taiwan University of Science and Technology, Tainan, Taiwan., Chen YC; Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan., Chang WT; School of Medicine, College of Medicine, National Sun Yat-sen university, Kaohsiung, Taiwan; Division of Cardiology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Hsu CC; Department of Emergency Medicine, Chi Mei Medical Center, Tainan, Taiwan; School of Medicine, College of Medicine, National Sun Yat-sen university, Kaohsiung, Taiwan., Lin HJ; Department of Emergency Medicine, Chi Mei Medical Center, Tainan, Taiwan; School of Medicine, College of Medicine, National Sun Yat-sen university, Kaohsiung, Taiwan; Department of Emergency Medicine, Taipei Medical University, Taipei, Taiwan., Chang CP; Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan., Guo HR; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Occupational and Environmental Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; Occupational Safety, Health and Medicine Research Center, National Cheng Kung University Hospital, Tainan, Taiwan. Electronic address: hrguo@mail.ncku.edu.tw.

المصدر: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Sep 15; Vol. 283, pp. 116772. Date of Electronic Publication: 2024 Jul 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE

مواضيع طبية MeSH: Carbon Monoxide Poisoning*/epidemiology , Hypothyroidism*/epidemiology , Hypothyroidism*/chemically induced, Animals ; Female ; Humans ; Male ; Taiwan/epidemiology ; Middle Aged ; Aged ; Adult ; Risk Factors

المؤلفون: Zhang S; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China., Yu H; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China., Zhao Y; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China., Gong A; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China., Guan C; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China., Chen S; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China., Xiao B; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China., Lu J; Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China. ljchb2h@hebmu.edu.cn.

المصدر: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2024 Sep 10; Vol. 24 (1), pp. 479. Date of Electronic Publication: 2024 Sep 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE

مواضيع طبية MeSH: Mendelian Randomization Analysis* , Hypothyroidism*/diagnosis , Hypothyroidism*/genetics , Hypothyroidism*/epidemiology , Thyroxine*/therapeutic use , Cardiovascular Diseases*/genetics , Cardiovascular Diseases*/epidemiology , Cardiovascular Diseases*/diagnosis , Genome-Wide Association Study* , Genetic Predisposition to Disease*, Humans ; Risk Assessment ; Hormone Replacement Therapy/adverse effects ; Risk Factors ; Phenotype ; Female ; Myocardial Infarction/genetics ; Myocardial Infarction/epidemiology ; Myocardial Infarction/diagnosis ; Polymorphism, Single Nucleotide ; Heart Failure/genetics ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Male ; Pharmacogenomic Variants ; Heart Disease Risk Factors

المؤلفون: Giacco A; Department of Science and Technologies, University of Sannio, Benevento, Italy., Petito G; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'L. Vanvitelli', Caserta, Italy., Silvestri E; Department of Science and Technologies, University of Sannio, Benevento, Italy., Scopigno N; Department of Science and Technologies, University of Sannio, Benevento, Italy., Vigliotti M; Department of Science and Technologies, University of Sannio, Benevento, Italy., Mercurio G; Department of Science and Technologies, University of Sannio, Benevento, Italy., de Lange P; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'L. Vanvitelli', Caserta, Italy., Lombardi A; Department of Biology, University of Naples Federico II, Napoli, Italy., Moreno M; Department of Science and Technologies, University of Sannio, Benevento, Italy., Goglia F; Department of Science and Technologies, University of Sannio, Benevento, Italy., Lanni A; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'L. Vanvitelli', Caserta, Italy., Senese R; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'L. Vanvitelli', Caserta, Italy., Cioffi F; Department of Science and Technologies, University of Sannio, Benevento, Italy.

المصدر: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Sep 05; Vol. 15, pp. 1432819. Date of Electronic Publication: 2024 Sep 05 (Print Publication: 2024).

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

مواضيع طبية MeSH: Hypothyroidism*/metabolism , Hypothyroidism*/chemically induced , Hypothyroidism*/drug therapy , Hypothyroidism*/pathology , Liver*/metabolism , Liver*/drug effects , Liver*/pathology , Nucleotidyltransferases*/metabolism , Inflammation*/metabolism , Inflammation*/drug therapy , Inflammation*/pathology , Diiodothyronines*/pharmacology , Membrane Proteins*/metabolism , Oxidative Stress*/drug effects, Animals ; Rats ; Male ; Triiodothyronine ; Mitochondria/metabolism ; Mitochondria/drug effects ; Rats, Wistar ; Mitochondria, Liver/metabolism ; Mitochondria, Liver/drug effects ; Mitochondria, Liver/pathology ; Signal Transduction/drug effects