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1دورية أكاديمية
المؤلفون: Joanne L. Parker, Justin C. Deme, Gabriel Kuteyi, Zhiyi Wu, Jiandong Huo, I. David Goldman, Raymond J. Owens, Philip C. Biggin, Susan M. Lea, Simon Newstead
المصدر: Nature, Nature. 595(7865):130-134
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المؤلفون: Tozammel Hoque, Susanne Aufreiter, Deborah L O'Connor, Richard H. Finnell, Constantine J. Georgiou, Reina Bendayan, I. David Goldman, Camille Alam
المصدر: Proceedings of the National Academy of Sciences. 116:17531-17540
مصطلحات موضوعية: Folate Receptor Alpha, 0303 health sciences, medicine.medical_specialty, Multidisciplinary, Calcitriol, Chemistry, Central nervous system, Calcitriol receptor, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Endocrinology, medicine.anatomical_structure, Downregulation and upregulation, Nuclear receptor, Internal medicine, medicine, Choroid plexus, 030217 neurology & neurosurgery, 030304 developmental biology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a1238e94d23cfbe5096c39859acfdac5
https://doi.org/10.1073/pnas.1907077116 -
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المؤلفون: Rongbao Zhao, Daniel Sanghoon Shin, Kai Lin, Andras Fiser, I. David Goldman, Srinivas Aluri
المصدر: J Biol Chem
The Journal of biological chemistry, vol 294, iss 18مصطلحات موضوعية: 0301 basic medicine, Biochemistry & Molecular Biology, K), GXXXDXXGR(R, Protein Conformation, membrane transport, Glycine, proton-coupled folate transporter, folate, Medical and Health Sciences, Biochemistry, Intestinal absorption, folate malabsorption disease, Cell membrane, 03 medical and health sciences, Membrane Biology, medicine, Humans, Cysteine, Homology modeling, protein motif, Structural motif, Molecular Biology, structural model, 030102 biochemistry & molecular biology, Chemistry, solute carrier family 46 member 1, Transporter, Cell Biology, Biological Sciences, Membrane transport, GXXXDXXGR(R/K), Kinetics, Transmembrane domain, 030104 developmental biology, medicine.anatomical_structure, Hela Cells, transporter, Chemical Sciences, Mutation, Biophysics, Generic health relevance, Proton-Coupled Folate Transporter, Intracellular, HeLa Cells
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607294eda5c98afb5c0e4647cfb75cf3
https://doi.org/10.1074/jbc.ra118.005533 -
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المؤلفون: He Qin Zhan, Mitra Najmi, Kai Lin, I. David Goldman, Rongbao Zhao, Srinivas Aluri, Andras Fiser
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Mutant, Folic Acid Deficiency, medicine.disease_cause, Biochemistry, Intestinal absorption, 03 medical and health sciences, Malabsorption Syndromes, Proton transport, medicine, Animals, Humans, Amino Acid Sequence, Cysteine, Molecular Biology, Loss function, Mutation, 030102 biochemistry & molecular biology, Chemistry, Mutagenesis, Transporter, Biological Transport, Molecular Bases of Disease, Cell Biology, Molecular biology, Protein Structure, Tertiary, Kinetics, 030104 developmental biology, Methotrexate, Mutagenesis, Site-Directed, Proton-Coupled Folate Transporter, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f4a04c2cd1b0b324a2c5499910f3ea
https://pubmed.ncbi.nlm.nih.gov/32893190 -
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المؤلفون: Rongbao Zhao, Andras Fiser, I. David Goldman, Srinivas Aluri
المصدر: American Journal of Physiology-Cell Physiology. 314:C289-C296
مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, 0301 basic medicine, Physiology, Pemetrexed, Structure-Activity Relationship, 03 medical and health sciences, Folic Acid, Protein Domains, medicine, Humans, Cysteine, Disulfides, Homology modeling, Proton-coupled folate transporter, Chemistry, Biological Transport, Transporter, Cell Biology, Apical membrane, Small intestine, Kinetics, Transmembrane domain, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, Mutation, Choroid plexus, Oxidation-Reduction, Proton-Coupled Folate Transporter, Research Article, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40f18aec7bae433251d25891f93750b
https://doi.org/10.1152/ajpcell.00215.2017 -
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المؤلفون: Rongbao Zhao, Andras Fiser, I. David Goldman, Srinivas Aluri
المصدر: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1859:2193-2202
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Biophysics, Biology, Biochemistry, Article, 03 medical and health sciences, Folic Acid, 0302 clinical medicine, Protein Domains, Humans, Protein Interaction Domains and Motifs, Homology modeling, Binding Sites, Cell Membrane, Membrane Proteins, Water, Transporter, Cell Biology, Membrane transport, Protein Transport, Transmembrane domain, 030104 developmental biology, Amino Acid Substitution, Intestinal folate absorption, 030220 oncology & carcinogenesis, Biotinylation, Helix, Mutant Proteins, Proton-Coupled Folate Transporter, Alpha helix, HeLa Cells, Protein Binding
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المصدر: Molecular Pharmaceutics. 14:3848-3858
مصطلحات موضوعية: Male, 0301 basic medicine, Folate Receptor Alpha, medicine.medical_specialty, Pharmaceutical Science, Blood–brain barrier, Calcitriol receptor, Article, Mice, Reduced Folate Carrier Protein, 03 medical and health sciences, Folic Acid, Calcitriol, Internal medicine, Drug Discovery, medicine, Animals, Humans, Rats, Wistar, Cells, Cultured, Chemistry, Neurodegeneration, Brain, Biological Transport, Transporter, medicine.disease, In vitro, Rats, Mice, Inbred C57BL, Methotrexate, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Nuclear receptor, Blood-Brain Barrier, Cancer research, Receptors, Calcitriol, Molecular Medicine, Choroid plexus
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المؤلفون: Susanna M. I. Goorden, Andras Fiser, Charlotte M A Lubout, I. David Goldman, Rongbao Zhao, Srinivas Aluri
المساهمون: Paediatric Metabolic Diseases, Laboratory Genetic Metabolic Diseases
المصدر: Blood advances, 2(1), 61-68. American Society of Hematology
مصطلحات موضوعية: 0301 basic medicine, Male, Models, Molecular, Arginine, Hematopoiesis and Stem Cells, Allosteric regulation, Mutant, Mutation, Missense, Folic Acid Deficiency, Transfection, Cell Line, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Malabsorption Syndromes, Humans, Tetrahydrofolates, biology, Chemistry, Infant, Hematology, Transport protein, Transmembrane domain, Protein Transport, 030104 developmental biology, Intestinal folate absorption, Amino Acid Substitution, Antifolate, Biophysics, biology.protein, Mutagenesis, Site-Directed, GLUT5, Proton-Coupled Folate Transporter, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63efd00d84d4d1bd5a16cc41592335e9
https://pure.amc.nl/en/publications/hereditary-folate-malabsorption-due-to-a-mutation-in-the-external-gate-of-the-protoncoupled-folate-transporter-slc46a1(5a58fe2a-9dc8-4ac2-b3ba-9cbe69e99b96).html -
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المؤلفون: I. David Goldman, David C. Spray, Srinivas Aluri, Rongbao Zhao, Mitra Najmi
المصدر: Molecular pharmacology. 93(3)
مصطلحات موضوعية: 0301 basic medicine, Protonophore, Bicarbonate, Intracellular pH, ATPase, Biological Transport, Active, Buffers, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tumor Microenvironment, Humans, Electrochemical gradient, Pharmacology, HEPES, Polyglutamate, biology, Articles, Hydrogen-Ion Concentration, 030104 developmental biology, Methotrexate, chemistry, Polyglutamic Acid, 030220 oncology & carcinogenesis, Antifolate, biology.protein, Biophysics, Molecular Medicine, Folic Acid Antagonists, Proton-Coupled Folate Transporter, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7cc82bbf1424b2e49f38c26ee8dcc3
https://pubmed.ncbi.nlm.nih.gov/29326243 -
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المؤلفون: I. David Goldman, Ersin Selcuk Unal, Rongbao Zhao, Mitra Najmi, Michele Visentin, Andras Fiser
المصدر: American Journal of Physiology-Cell Physiology. 308:C631-C641
مصطلحات موضوعية: Models, Molecular, Guanine, Physiology, Pemetrexed, Intestinal absorption, chemistry.chemical_compound, Folic Acid, Glutamates, Cell Line, Tumor, Humans, Amino Acid Sequence, Binding site, Tyrosine, Peptide sequence, Binding Sites, Biological Transport, Transporter, Articles, Cell Biology, Hydrogen-Ion Concentration, Protein Structure, Tertiary, Methotrexate, Amino Acid Substitution, Intestinal Absorption, Intestinal folate absorption, Biochemistry, chemistry, Choroid plexus, Proton-Coupled Folate Transporter, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200ee031745d2f43d68c6297c35718f6
https://doi.org/10.1152/ajpcell.00238.2014