المؤلفون: Siti Farah Rahmawati, Rémon Vos, I. Sophie T. Bos, Huib A. M. Kerstjens, Loes E. M. Kistemaker, Reinoud Gosens

المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/743b1d96993347b7928470e65d4f95bf

المؤلفون: Mariska P. M. van den Berg, Susan Nijboer-Brinksma, I. Sophie T. Bos, Maarten van den Berge, David Lamb, Martijn van Faassen, Ido P. Kema, Reinoud Gosens, Loes E. M. Kistemaker

المصدر: Respiratory Research, Vol 22, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Asthma, Airway hyperresponsiveness, Airway smooth muscle, Mast cell, Sensory neuron, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1465-993X

URL الوصول: https://doaj.org/article/390589a8cf6b4bccb3ab15de0bce3098

المؤلفون: Xinhui Wu, Eline M. van Dijk, John-Poul Ng-Blichfeldt, I. Sophie T. Bos, Chiara Ciminieri, Melanie Königshoff, Loes E.M. Kistemaker, Reinoud Gosens

المصدر: Cells, Vol 8, Iss 10, p 1147 (2019)

مصطلحات موضوعية: chronic obstructive pulmonary disease (copd), alveolar repair, wnt-5a, wnt-5b, wnt signaling pathway, precision-cut-lung slices (pcls), lung organoids, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/8/10/1147; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/1b105df851b94cd7bd6d206157ae114e

المؤلفون: Miranda Van Eck, Menno Hoekstra, Ruud Out, I. Sophie T. Bos, J. Kar Kruijt, Reeni B. Hildebrand, Theo J.C. Van Berkel

المصدر: Journal of Lipid Research, Vol 49, Iss 1, Pp 136-146 (2008)

مصطلحات موضوعية: liver, hepatocytes, gene expression, mouse model, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520428883; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/ca8fdea9dea040ed841d2d639b08f1ee

المؤلفون: Xinhui Wu, Chiara Ciminieri, I. Sophie T. Bos, Manon E. Woest, Angela D'Ambrosi, René Wardenaar, Diana C.J. Spierings, Melanie Königshoff, Martina Schmidt, Loes E.M. Kistemaker, Reinoud Gosens

المساهمون: Molecular Pharmacology, Damage and Repair in Cancer Development and Cancer Treatment (DARE), Stem Cell Aging Leukemia and Lymphoma (SALL), Groningen Research Institute for Asthma and COPD (GRIAC)

المصدر: Environmental Pollution, 305:119292. ELSEVIER SCI LTD

مصطلحات موضوعية: EXPRESSION, Lung repair, Health, Toxicology and Mutagenesis, Air pollution, Epithelial Cells, General Medicine, Fibroblasts, Toxicology, Organoids, ACTIVATION, PATHWAY, Pulmonary Disease, Chronic Obstructive, CYTOCHROMES P450 1A1, ACUTE EXACERBATION, DNA-DAMAGE, INFLAMMATION, POLLUTION, Oxidative stress, AIRWAY-RESISTANCE, WNT signaling, Humans, Lung, beta Catenin, Vehicle Emissions

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe7ac5003e1a9c0e2cd56edd7fa7ebe
https://research.rug.nl/en/publications/7fe6a1e9-97e2-4c86-987c-007712f60a05

المؤلفون: Xinhui Wu, I. Sophie T. Bos, Thomas M. Conlon, Meshal Ansari, Vicky Verschut, Luke van der Koog, Lars A. Verkleij, Angela D’Ambrosi, Aleksey Matveyenko, Herbert B. Schiller, Melanie Königshoff, Martina Schmidt, Loes E. M. Kistemaker, Ali Önder Yildirim, Reinoud Gosens

المساهمون: Groningen Research Institute for Asthma and COPD (GRIAC), Molecular Pharmacology

المصدر: Science Advances, 8(12):eabj9949. AMER ASSOC ADVANCEMENT SCIENCE

مصطلحات موضوعية: Mice, Pulmonary Disease, Chronic Obstructive, Multidisciplinary, Animals, Humans, Regeneration, Ligands, Transcriptome, Lung

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c9dcf85b59f4fb1b32ac6293df49d7
https://doi.org/10.1126/sciadv.abj9949

المؤلفون: Loes E. M. Kistemaker, Reinoud Gosens, Martina Schmidt, Herbert B. Schiller, Vicky Verschut, Lars A. Verkleij, Melanie Königshoff, Angela D’Ambrosi, Xinhui Wu, I. Sophie T. Bos, Thomas M. Conlon, Meshal Ansari, Ali Önder Yildirim, Aleksey V. Matveyenko

مصطلحات موضوعية: COPD, Lung, business.industry, Regeneration (biology), Druggability, Cell cycle, medicine.disease, medicine.anatomical_structure, In vivo, Cancer research, medicine, Progenitor cell, business, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eb9112397153c8618fcd64db07ac4aaa
https://doi.org/10.1101/2021.05.18.444655

المؤلفون: Herman Meurs, Yun Liu, I. Sophie T. Bos, Anna K. H. Hirsch, Tjitske A. Oenema, H. Maarsingh

المساهمون: HIPS, Helmholtz-Institut für pharmazeutische Forschung Saarland, Universitätscampus 8.1, 66123 Saarbrücken, Germany., Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC), Chemical Biology 2

المصدر: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
European Journal of Pharmaceutics and Biopharmaceutics, 130, 123-127. ELSEVIER SCIENCE BV

مصطلحات موضوعية: 0301 basic medicine, Budesonide, PHARMACOKINETICS, Chemistry, Pharmaceutical, Anti-Inflammatory Agents, CORTICOSTEROIDS, Biological Availability, Pharmaceutical Science, 02 engineering and technology, Pharmacology, Micelle, THERAPY, Cell Line, 03 medical and health sciences, Drug Delivery Systems, Lipid-DNA, Pharmacokinetics, AIRWAY SMOOTH-MUSCLE, medicine, Humans, DRUG-DELIVERY, Glucocorticoids, Micelles, Drug Carriers, Chemistry, Interleukin-8, DNA, General Medicine, 021001 nanoscience & nanotechnology, Lipids, POLYMERIC MICELLES, CROHNS-DISEASE, Bioavailability, RHEUMATOID-ARTHRITIS, 030104 developmental biology, Solubility, ULCERATIVE-COLITIS, Critical micelle concentration, Drug delivery, ASTHMA, Anti-inflammatory, 0210 nano-technology, Drug carrier, Hydrophobic and Hydrophilic Interactions, Glucocorticoid, Biotechnology, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137c1f7aef390b3b77da91d5c3cc0718
https://hdl.handle.net/11370/b0933bf2-0412-419b-aad6-a1370e7537b3

المؤلفون: Mariska P. M. van den Berg, Susan Nijboer-Brinksma, Martijn van Faassen, Maarten van den Berge, David J. Lamb, Ido P. Kema, Reinoud Gosens, I. Sophie T. Bos, Loes E. M. Kistemaker

المساهمون: Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC)

المصدر: Respiratory Research, Vol 22, Iss 1, Pp 1-15 (2021)
Respiratory Research
Respiratory Research, 22(1):48. BioMed Central Ltd.

مصطلحات موضوعية: 0301 basic medicine, Male, Ovalbumin, Bronchoconstriction, Guinea Pigs, Inflammation, Pilot Projects, Pharmacology, Mast cell, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Organ Culture Techniques, Airway hyperresponsiveness, In vivo, Administration, Inhalation, medicine, Animals, Humans, Lung, TRPA1 Cation Channel, lcsh:RC705-779, Sensory neuron, biology, Dose-Response Relationship, Drug, business.industry, Research, lcsh:Diseases of the respiratory system, respiratory system, Asthma, Bronchodilator Agents, respiratory tract diseases, Airway smooth muscle, 030104 developmental biology, medicine.anatomical_structure, 030228 respiratory system, chemistry, biology.protein, medicine.symptom, business, Ex vivo, Histamine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a946ee64706f3f8dba2fb772d54d44a
https://doi.org/10.21203/rs.3.rs-88800/v1

المؤلفون: Maarten van den Berge, Tim Koopmans, Mark H. Menzen, Victor Guryev, Ron Smits, Gerard H. Koppelman, Reinoud Gosens, I. Sophie T. Bos, Laura Hesse, Kuldeep Kumawat, Elvira R M Bakker, Martijn C. Nawijn

المساهمون: Molecular Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC), Gastroenterology & Hepatology

المصدر: Scientific Reports
Scientific Reports, 10(1):6754. Nature Publishing Group
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, NF-KAPPA-B, lcsh:Medicine, Lymphocyte Activation, ACTIVATION, Mice, 0302 clinical medicine, Cell Movement, Transgenes, MACROPHAGES, WNT-5A, lcsh:Science, Lung, GENE-EXPRESSION, Multidisciplinary, Molecular medicine, biology, Chemistry, INDUCTION, respiratory system, BRONCHIAL THERMOPLASTY, WINGLESS HOMOLOG, embryonic structures, Airway Remodeling, Female, medicine.symptom, Genetically modified mouse, Ovalbumin, Primary Cell Culture, Mice, Transgenic, Inflammation, Wnt-5a Protein, Article, 03 medical and health sciences, Downregulation and upregulation, medicine, Animals, Humans, Interleukin 4, Actin, Bronchial thermoplasty, Interleukins, lcsh:R, Muscle, Smooth, Allergens, Immunoglobulin E, NFKB1, Actins, respiratory tract diseases, Eosinophils, body regions, 030104 developmental biology, Gene Expression Regulation, 030228 respiratory system, Immunology, CELLS, biology.protein, ASTHMA, lcsh:Q, Interleukin-4, sense organs, Interleukin-5

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed7ca186f3b0f890f4a31d7f8152189
https://doi.org/10.1038/s41598-020-63741-x