نتائج البحث - "II-THE-BRAIN"

المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Medical oncology, CCA - Imaging and biomarkers

المصدر: Clinical Cancer Research, 25(12), 3517-3527. AMER ASSOC CANCER RESEARCH
Clinical Cancer Research, 25(12), 3517-3527. American Association for Cancer Research Inc.
Moek, K L, Waaijer, S J H, Kok, I C, Suurs, F V, Brouwers, A H, Menke-van der Houven van Oordt, C W, Wind, T T, Gietema, J A, Schröder, C P, Mahesh, S V K, Jorritsma-Smit, A, Lub-de Hooge, M N, Fehrmann, R S N, de Groot, D J A & de Vries, E G E 2019, ' 89Zr-labeled bispecific T-cell engager AMG 211 PET shows AMG 211 accumulation in CD3-rich tissues and clear, heterogeneous tumor uptake ', Clinical Cancer Research, vol. 25, no. 12, pp. 3517-3527 . https://doi.org/10.1158/1078-0432.CCR-18-2918

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b620c88938cb0ca928adfecd837ee0c
https://research.rug.nl/en/publications/847e9ed8-03a1-423a-afec-1517d6324580

7

Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease

المؤلفون: van der Made, Thomas K, Fedecostante, Michele, Scotcher, Daniel, Rostami-Hodjegan, Amin, Sastre Toraño, Javier, Middel, Igor, Koster, Andries S, Gerritsen, Karin G, Jankowski, Vera, Jankowski, Joachim, Hoenderop, Joost G J, Masereeuw, Rosalinde, Galetin, Aleksandra, Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Pharmacology, Chemical Biology and Drug Discovery

المساهمون: Pathologie, RS: CARIM - R3 - Vascular biology, RS: Carim - B07 The vulnerable plaque: makers and markers, Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Pharmacology, Chemical Biology and Drug Discovery

المصدر: Molecular Pharmaceutics, 16(11), 4551-4562. American Chemical Society
Molecular Pharmaceutics, 16, 4551. American Chemical Society
Molecular Pharmaceutics, 16, 11, pp. 4551-4562
Van Der Made, T K, Fedecostante, M, Scotcher, D, Rostami-hodjegan, A, Sastre Torano, J, Middel, I, Koster, A S, Gerritsen, K G, Jankowski, V, Jankowski, J, Hoenderop, J G J, Masereeuw, R & Galetin, A 2019, ' Quantitative translation of microfluidic transporter in vitro data to in vivo reveals impaired albumin-facilitated indoxyl sulfate secretion in chronic kidney disease ', Molecular Pharmaceutics, vol. 16, no. 11, pp. 4551–4562 . https://doi.org/10.1021/acs.molpharmaceut.9b00681
Molecular Pharmaceutics, 16, 4551-4562

مصطلحات موضوعية: Organic anion transporter 1, PREDICTION, Pharmaceutical Science, PROTEIN, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, OAT1, 03 medical and health sciences, 0302 clinical medicine, All institutes and research themes of the Radboud University Medical Center, In vivo, proximal tubule, Drug Discovery, medicine, CKD, Secretion, indoxyl sulfate, UREMIC TOXINS, PLASMA-LEVELS, in vitro-in vivo extrapolation, DRUG-DRUG INTERACTIONS, ORGANIC ANION TRANSPORTERS, biology, Chemistry, Albumin, Transporter, EFFLUX TRANSPORTERS, 021001 nanoscience & nanotechnology, Human serum albumin, In vitro, RENAL CLEARANCE, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Renal physiology, II-THE-BRAIN, biology.protein, Molecular Medicine, 0210 nano-technology, medicine.drug, P-CRESOL SULFATE