المؤلفون: Romero-Castillo L; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Li T; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Do NN; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596, Frankfurt am Main, Germany., Sareila O; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden.; Medical Inflammation Research, MediCity Research Laboratory, University of Turku, Turku, FI-20520, Finland., Xu B; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Hennings V; Department of Pediatrics, Institute of Clinical Sciences and Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, 41345, Sweden., Xu Z; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Svensson C; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Oliveira-Coelho A; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Sener Z; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Urbonaviciute V; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Ekwall O; Department of Pediatrics, Institute of Clinical Sciences and Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, 41345, Sweden., Burkhardt H; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596, Frankfurt am Main, Germany.; Division of Rheumatology, University Hospital Frankfurt, Goethe University, 60590, Frankfurt am Main, Germany., Holmdahl R; Medical Inflammation Research, Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden.; Medical Inflammation Research, MediCity Research Laboratory, University of Turku, Turku, FI-20520, Finland.

المصدر: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Jun; Vol. 11 (23), pp. e2401513. Date of Electronic Publication: 2024 Apr 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Rheumatoid*/genetics , Arthritis, Rheumatoid*/immunology , Antigens, Differentiation, B-Lymphocyte*/genetics , Antigens, Differentiation, B-Lymphocyte*/immunology , Disease Models, Animal* , Mice, Inbred C57BL* , Mice, Transgenic* , Gene Knock-In Techniques*/methods , Histocompatibility Antigens Class II*/genetics , Histocompatibility Antigens Class II*/immunology , Alleles*, Animals ; Mice ; Humans ; Arthritis, Experimental/genetics ; Arthritis, Experimental/immunology ; HLA-DRB1 Chains/genetics ; HLA-DRB1 Chains/immunology ; Collagen Type II/genetics ; Collagen Type II/immunology

المؤلفون: Yan X; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China.; School of Stomatology, Qingdao University, Qingdao, China., Zhang Q; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China.; School of Stomatology, Qingdao University, Qingdao, China., Zhang M; Department of Pathology, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China., He Z; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China.; School of Stomatology, Qingdao University, Qingdao, China., Liu R; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China., Liu J; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China., Ren D; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China.; School of Stomatology, Qingdao University, Qingdao, China., Zeng X; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China.; School of Stomatology, Qingdao University, Qingdao, China., Lv T; Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, China., Yuan X; Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, China.; School of Stomatology, Qingdao University, Qingdao, China.

المصدر: Journal of oral rehabilitation [J Oral Rehabil] 2024 Aug; Vol. 51 (8), pp. 1507-1520. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0433604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2842 (Electronic) Linking ISSN: 0305182X NLM ISO Abbreviation: J Oral Rehabil Subsets: MEDLINE

مواضيع طبية MeSH: Bone Morphogenetic Protein Receptors, Type II*/metabolism , Bone Morphogenetic Protein Receptors, Type II*/genetics , Cell Differentiation*/physiology , Chondrogenesis*/physiology , Mesenchymal Stem Cells*/metabolism , MicroRNAs*/metabolism , MicroRNAs*/genetics , Signal Transduction*/physiology , Stress, Mechanical* , Synovial Membrane*/cytology , Synovial Membrane*/metabolism, Humans ; Aggrecans/metabolism ; Aggrecans/genetics ; Cells, Cultured ; Collagen Type II/metabolism ; Collagen Type II/genetics ; Smad Proteins/metabolism ; SOX9 Transcription Factor/metabolism ; SOX9 Transcription Factor/genetics

المؤلفون: Ng RR; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Lin Z; Department of Biology, Shantou University, Shantou, Guangdong, China., Zhang Y; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Ti SC; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Javed A; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Wong JWH; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Fang Q; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Leung JWC; Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Tang AHN; Department of Pathology, School of Clinical Medicine LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Huen MSY; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R.; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Pokfulam, Hong Kong S.A.R.

المصدر: Science advances [Sci Adv] 2024 Jul 19; Vol. 10 (29), pp. eadm9577. Date of Electronic Publication: 2024 Jul 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Androgens*/metabolism , Receptors, Androgen*/metabolism , Receptors, Androgen*/genetics , R-Loop Structures* , Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/metabolism , Prostatic Neoplasms*/pathology , RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics, Humans ; Male ; Cell Line, Tumor ; DNA Topoisomerases, Type II/metabolism ; DNA Topoisomerases, Type II/genetics ; Transcription, Genetic ; DNA Breaks, Double-Stranded ; Transcription Initiation Site ; Gene Expression Regulation, Neoplastic ; Protein Binding ; Transcriptional Activation

المؤلفون: El Hamaky NFM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Hamdi A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: Abdelrahmanhamdi2012@mans.edu.eg., Bayoumi WA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Elgazar AA; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt., Nasr MNA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University, New Damietta 34518, Egypt.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Jul; Vol. 148, pp. 107437. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Molecular Docking Simulation* , Triazoles*/chemistry , Triazoles*/pharmacology , Triazoles*/chemical synthesis , Drug Screening Assays, Antitumor* , Drug Design* , Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-2*/metabolism , ErbB Receptors*/antagonists & inhibitors , ErbB Receptors*/metabolism , Cell Proliferation*/drug effects , DNA Topoisomerases, Type II*/metabolism , Dose-Response Relationship, Drug*, Humans ; Structure-Activity Relationship ; Molecular Structure ; Quinazolines/pharmacology ; Quinazolines/chemistry ; Quinazolines/chemical synthesis ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/chemical synthesis ; Apoptosis/drug effects ; Cell Line, Tumor ; Topoisomerase II Inhibitors/pharmacology ; Topoisomerase II Inhibitors/chemistry ; Topoisomerase II Inhibitors/chemical synthesis

المؤلفون: Luo Y; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Li J; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Li X; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Lin H; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Mao Z; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Xu Z; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Li S; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Nie C; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Zhou XA; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Liao J; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Xiong Y; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China., Xu X; Guangdong Key Laboratory for Genome Stability & Disease Prevention and Carson International Cancer Center, Marshall Laboratory of Biomedical Engineering, Shenzhen University Medical School, Shenzhen 518055, China., Wang J; Department of Radiation Medicine, School of Basic Medical Sciences, Peking University International Cancer Institute, Institute of Advanced Clinical Medicine, State Key Laboratory of Molecular Oncology, Peking University Health Science Center, Beijing 100191, China.; Department of Gastrointestinal Translational Research, Peking University Cancer Hospital, Beijing 100142, China.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jun 11; Vol. 121 (24), pp. e2404383121. Date of Electronic Publication: 2024 Jun 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: DNA Repair Enzymes*/metabolism , DNA Repair Enzymes*/genetics , RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics , Poly-ADP-Ribose Binding Proteins*/metabolism , Poly-ADP-Ribose Binding Proteins*/genetics , DNA Repair* , DNA Helicases*/metabolism , DNA Helicases*/genetics , Cockayne Syndrome*/genetics , Cockayne Syndrome*/metabolism, Humans ; Animals ; Mice ; Transcription, Genetic ; Phosphorylation ; Casein Kinase II/metabolism ; Casein Kinase II/genetics ; Mice, Knockout ; DNA Damage ; ATPases Associated with Diverse Cellular Activities/metabolism ; ATPases Associated with Diverse Cellular Activities/genetics ; Chromatin/metabolism ; Ubiquitination ; Excision Repair

المؤلفون: Lukoszek R; School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Inesta-Vaquera F; School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK; Department of Biochemistry and Molecular Biology and Genetics, School of Sciences, Universidad de Extremadura, Avenida de Elvas, s/n, 06006 Badajoz, Spain., Brett NJM; School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Liang S; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Hepburn LA; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Hughes DJ; School of Biology, University of St Andrews, Biomedical Sciences Research Complex, St Andrews KY16 9ST, UK., Pirillo C; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Roberts EW; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK., Cowling VH; School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK. Electronic address: victoria.cowling@glasgow.ac.uk.

المصدر: Cell reports [Cell Rep] 2024 Jul 23; Vol. 43 (7), pp. 114405. Date of Electronic Publication: 2024 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Casein Kinase II*/metabolism , Casein Kinase II*/genetics , Methyltransferases*/metabolism , RNA Caps*/metabolism, Animals ; Humans ; HEK293 Cells ; Influenza A virus ; Influenza, Human/virology ; Influenza, Human/metabolism ; Influenza, Human/genetics ; Methylation ; Phosphorylation ; RNA Polymerase II/metabolism

المؤلفون: Amoiridis M; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK.; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, Illkirch, France.; Université de Strasbourg, Illkirch, France., Verigos J; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Meaburn K; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Gittens WH; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Ye T; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, Illkirch, France.; Université de Strasbourg, Illkirch, France., Neale MJ; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK., Soutoglou E; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, BN1 9RH, UK. E.Soutoglou@sussex.ac.uk.

المصدر: Nature communications [Nat Commun] 2024 Jul 08; Vol. 15 (1), pp. 5727. Date of Electronic Publication: 2024 Jul 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: DNA Topoisomerases, Type II*/metabolism , DNA Topoisomerases, Type II*/genetics , Heterochromatin*/metabolism, Animals ; Topoisomerase II Inhibitors/pharmacology ; Repetitive Sequences, Nucleic Acid/genetics ; Poly-ADP-Ribose Binding Proteins/metabolism ; Poly-ADP-Ribose Binding Proteins/genetics ; DNA Replication ; DNA, Superhelical/metabolism ; DNA, Superhelical/chemistry ; Humans ; Mice ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; DNA/metabolism ; DNA/chemistry ; Interphase

المؤلفون: Mercado-Sánchez I; División de Ciencias Naturales y Exactas, Departamento de Química, Universidad de Guanajuato, Guanajuato, Mexico., López J; Departamento de Química Orgánica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, Mexico., Chávez-Rocha R; División de Ciencias Naturales y Exactas, Departamento de Química, Universidad de Guanajuato, Guanajuato, Mexico., Vargas-Rodríguez I; División de Ciencias Naturales y Exactas, Departamento de Química, Universidad de Guanajuato, Guanajuato, Mexico., Bazán-Jiménez A; División de Ciencias Naturales y Exactas, Departamento de Química, Universidad de Guanajuato, Guanajuato, Mexico., Segovia-Mendoza M; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, Mexico., Prado-Garcia H; Laboratorio de Onco-Inmunobiologia, Departamento de Enfermedades Crónico-Degenerativas, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Ciudad de México, Mexico., Vázquez MA; División de Ciencias Naturales y Exactas, Departamento de Química, Universidad de Guanajuato, Guanajuato, Mexico., García-Becerra R; Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de Mexico, Mexico.; Programa de Investigación de Cáncer de Mama, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, Mexico., Garcia-Revilla MA; División de Ciencias Naturales y Exactas, Departamento de Química, Universidad de Guanajuato, Guanajuato, Mexico.

المصدر: Chemical biology & drug design [Chem Biol Drug Des] 2024 Jul; Vol. 104 (1), pp. e14596.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

مواضيع طبية MeSH: Naphthoquinones*/chemistry , Naphthoquinones*/pharmacology , Doxorubicin*/pharmacology , Doxorubicin*/chemistry , DNA Topoisomerases, Type II*/metabolism , Molecular Docking Simulation* , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Cell Proliferation*/drug effects, Humans ; Cell Line, Tumor ; MCF-7 Cells ; Drug Screening Assays, Antitumor ; Topoisomerase II Inhibitors/pharmacology ; Topoisomerase II Inhibitors/chemistry ; Topoisomerase II Inhibitors/chemical synthesis ; Topoisomerase II Inhibitors/metabolism ; DNA Cleavage/drug effects

المؤلفون: Elkanzi NAA; Chemistry Department, college of Science, Jouf University, 2014, Sakaka, Saudi Arabia., Hrichi H; Chemistry Department, college of Science, Jouf University, 2014, Sakaka, Saudi Arabia., Muqbil Alsirhani A; Chemistry Department, college of Science, Jouf University, 2014, Sakaka, Saudi Arabia., Bakr RB; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Beni-Suef University, 62514, Beni-Suef, Egypt.

المصدر: Chemistry & biodiversity [Chem Biodivers] 2024 Jun; Vol. 21 (6), pp. e202301746. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Anti-Bacterial Agents*/chemistry , Antifungal Agents*/pharmacology , Antifungal Agents*/chemical synthesis , Antifungal Agents*/chemistry , Antioxidants*/pharmacology , Antioxidants*/chemical synthesis , Antioxidants*/chemistry , DNA Topoisomerases, Type II*/metabolism , Drug Design* , Fungi*/drug effects , Microbial Sensitivity Tests* , Naphthyridines*/pharmacology , Naphthyridines*/chemistry , Naphthyridines*/chemical synthesis, Bacteria/drug effects ; beta-Lactams/chemical synthesis ; beta-Lactams/chemistry ; beta-Lactams/pharmacology ; Biphenyl Compounds/antagonists & inhibitors ; Molecular Docking Simulation ; Molecular Structure ; Picrates/antagonists & inhibitors ; Structure-Activity Relationship ; Topoisomerase II Inhibitors/pharmacology ; Topoisomerase II Inhibitors/chemistry ; Topoisomerase II Inhibitors/chemical synthesis ; Spiro Compounds/chemical synthesis ; Spiro Compounds/chemistry ; Spiro Compounds/pharmacology

المؤلفون: Cowell IG; Biosciences Institute, Newcastle University, UK., Austin CA; Biosciences Institute, Newcastle University, UK.

المصدر: FEBS open bio [FEBS Open Bio] 2024 Jun; Vol. 14 (6), pp. 1001-1010. Date of Electronic Publication: 2024 Mar 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE

مواضيع طبية MeSH: Etoposide*/pharmacology , Peroxidase*/metabolism , DNA Damage*/drug effects , DNA Topoisomerases, Type II*/metabolism , Poly-ADP-Ribose Binding Proteins*/metabolism , Poly-ADP-Ribose Binding Proteins*/antagonists & inhibitors, Humans ; Topoisomerase II Inhibitors/pharmacology ; Antineoplastic Agents/pharmacology ; DNA Breaks, Double-Stranded/drug effects ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism