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1
المؤلفون: Robert K. Y. Cheng, Celia Dominguez, Osamu Ichihara, Douglas Macdonald, Ignacio Munoz-Sanjuan, Mark A. Brooks, Andreas Ebneth, Leticia Toledo-Sherman, Michael Prime, Ian Toogood-Johnson, Sayeh Erfan, John Wityak, Richard W Marston, Frederick Arthur Brookfield, Darshan Gunvant Vaidya, Stephen Martin Courtney, Peter Johnson, Anna Pedret-Dunn, Andreas Scheel, Dirk Winkler, Christopher John Yarnold, Sabine Schaertl, Ole A. Andersen, Shilpa Palan, Maria Beconi, Brunella Felicetti, Siw F. Johnsen, John J. Barker, Jordan J. Palfrey, Ina Sternberger
المصدر: Journal of Medicinal Chemistry. 55:1021-1046
مصطلحات موضوعية: Male, Models, Molecular, Cell Membrane Permeability, Pyridines, Tissue transglutaminase, Lysine, In Vitro Techniques, Piperazines, Mice, Structure-Activity Relationship, Huntington's disease, GTP-Binding Proteins, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Protein Glutamine gamma Glutamyltransferase 2, chemistry.chemical_classification, Acrylamides, Sulfonamides, Isopeptide bond, Transglutaminases, biology, medicine.disease, Molecular biology, In vitro, Rats, Glutamine, HEK293 Cells, Huntington Disease, Pyrimidines, Enzyme, Biochemistry, chemistry, Microsomes, Liver, biology.protein, Molecular Medicine, Caco-2 Cells
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2
المؤلفون: Wayne Thomas, Ian Toogood-Johnson, Stephen P. East, Andrew Paul Ayscough, Steven S. Taylor
المصدر: Bioorganicmedicinal chemistry letters. 21(13)
مصطلحات موضوعية: Peptidomimetic, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, medicine.disease_cause, Biochemistry, Haemophilus influenzae, Amidohydrolases, Peptide deformylase, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Drug Discovery, medicine, Moiety, Amines, Molecular Biology, Antibacterial agent, Aza Compounds, Hydroxamic acid, Organic Chemistry, Biological activity, Anti-Bacterial Agents, chemistry, Cyclization, Molecular Medicine, Peptidomimetics, Antibacterial activity
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3
المؤلفون: Mark Whittaker, Ian Toogood-Johnson, Shilpa Palan, Brunella Felicetti, John Barker, Robert K. Y. Cheng, Christoph Scheich, Thomas Hesterkamp
المصدر: Protein science : a publication of the Protein Society. 19(1)
مصطلحات موضوعية: Models, Molecular, Adenine binding, Protein-Serine-Threonine Kinases, Crystallography, Ligand, Kinase, Recombinant Fusion Proteins, Intracellular Signaling Peptides and Proteins, Plasma protein binding, Biology, Protein Serine-Threonine Kinases, Ligands, Biochemistry, Small molecule, chemistry.chemical_compound, chemistry, Protein Structure Report, Catalytic Domain, Transferase, Humans, Molecular Biology, Lead compound, Protein Binding
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4
المؤلفون: Ian Toogood-Johnson, Claudia Albrecht, Mark Whittaker, David Hallett, Ole A. Andersen, Brunella Felicetti, Dorian Leo Schönfeld, Tara Fryatt, John Barker
المصدر: Acta crystallographica. Section D, Biological crystallography. 65(Pt 8)
مصطلحات موضوعية: Stereochemistry, Phosphodiesterase Inhibitors, Protein Conformation, Crystallography, X-Ray, Ligands, law.invention, Crystal, chemistry.chemical_compound, Protein structure, Structural Biology, law, Papaverine, Humans, Crystallization, Ligand, Phosphoric Diester Hydrolases, General Medicine, Crystallography, Monomer, Cross-Linking Reagents, chemistry, Glutaral, Multiprotein Complexes, X-ray crystallography, Protein crystallization, Protein ligand, Protein Binding
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