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المؤلفون: Christian B M, Poulie, Eline, Pottie, Icaro A, Simon, Kasper, Harpsøe, Laura, D'Andrea, Igor V, Komarov, David E, Gloriam, Anders A, Jensen, Christophe P, Stove, Jesper L, Kristensen
المصدر: Journal of medicinal chemistry. 65(18)
مصطلحات موضوعية: Lysergic Acid Diethylamide, Serotonin, Hallucinogens, Receptor, Serotonin, 5-HT2A, Serotonin 5-HT2 Receptor Agonists, beta-Arrestins
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المؤلفون: Sijie Huang, Peiyu Xu, Dan-Dan Shen, Icaro A. Simon, Chunyou Mao, Yangxia Tan, Huibing Zhang, Kasper Harpsøe, Huadong Li, Yumu Zhang, Chongzhao You, Xuekui Yu, Yi Jiang, Yan Zhang, David E. Gloriam, H. Eric Xu
المساهمون: Medicinal chemistry, AIMMS
المصدر: Huang, S, Xu, P, Shen, D D, Simon, I A, Mao, C, Tan, Y, Zhang, H, Harpsøe, K, Li, H, Zhang, Y, You, C, Yu, X, Jiang, Y, Zhang, Y, Gloriam, D E & Xu, H E 2022, ' GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors ', Molecular cell, vol. 82, no. 14, pp. 2681-2695.e6 . https://doi.org/10.1016/j.molcel.2022.05.031
Molecular cell, 82(14), 2681-2695.e6. Cell Pressمصطلحات موضوعية: ligand selectivity, serotonin receptor, GPCR, 5-HT, cryo-EM structure, Cell Biology, G protein selectivity, Molecular Biology, 5-HT receptor, signaling complex
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c14e6f3505ee05c519a1463efa9c29
https://hdl.handle.net/1871.1/713d857a-269d-42a6-a385-466fed3a7d58 -
3دورية أكاديمية
المؤلفون: Peiyu Xu, Sijie Huang, Huibing Zhang, Chunyou Mao, X. Edward Zhou, Xi Cheng, Icaro A. Simon, Dan-Dan Shen, Hsin-Yung Yen, Carol V. Robinson, Kasper Harpsøe, Bo Svensson, Jia Guo, Hualiang
المصدر: Nature, Nature. 592(7854):469-473
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المؤلفون: Laura D'Andrea, Anders Asbjørn Jensen, Jesper Kristensen, Igor Komarov, Christophe Stove, Kasper Harpsøe, David Gloriam, Icaro Ariel Simon, Eline Pottie, Christian Poulie
المصدر: JOURNAL OF MEDICINAL CHEMISTRY
Poulie, C B M, Pottie, E, Simon, I A, Harpsøe, K, D’andrea, L, Komarov, I V, Gloriam, D E, Jensen, A A, Stove, C P & Kristensen, J L 2022, ' Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT 2A Receptor Agonists ', Journal of Medicinal Chemistry, vol. 65, no. 18, pp. 12031–12043 . https://doi.org/10.1021/acs.jmedchem.2c00702مصطلحات موضوعية: ACCURATE DOCKING, GLIDE, PSILOCYBIN, SEROTONIN, LYSERGIC-ACID DIETHYLAMIDE, RECEPTORS, Chemistry, DOUBLE-BLIND, LSD-ASSISTED PSYCHOTHERAPY, Drug Discovery, Medicine and Health Sciences, Molecular Medicine, ANXIETY, LIGANDS, PROTEIN-COUPLED
وصف الملف: application/pdf
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المؤلفون: Sijie, Huang, Peiyu, Xu, Dan-Dan, Shen, Icaro A, Simon, Chunyou, Mao, Yangxia, Tan, Huibing, Zhang, Kasper, Harpsøe, Huadong, Li, Yumu, Zhang, Chongzhao, You, Xuekui, Yu, Yi, Jiang, Yan, Zhang, David E, Gloriam, H Eric, Xu
المصدر: Molecular cell. 82(14)
مصطلحات موضوعية: Serotonin, GTP-Binding Proteins, Receptors, Serotonin, Ligands, Receptors, G-Protein-Coupled
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6d0c441213f48aaff5ea42671a756862
https://pubmed.ncbi.nlm.nih.gov/35714614
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