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المؤلفون: Alina Kulakova, Dillen Augustijn, Inas El Bialy, Lorenzo Gentiluomo, Maria Laura Greco, Stefan Hervø-Hansen, Sowmya Indrakumar, Sujata Mahapatra, Marcello Martinez Morales, Christin Pohl, Marco Polimeni, Aisling Roche, Hristo L. Svilenov, Andreas Tosstorff, Matja Zalar, Robin Curtis, Jeremy P. Derrick, Wolfgang Frieß, Alexander P. Golovanov, Mikael Lund, Allan Nørgaard, Tarik A. Khan, Günther H. J. Peters, Alain Pluen, Dierk Roessner, Werner W. Streicher, Christopher F. van der Walle, Jim Warwicker, Shahid Uddin, Gerhard Winter, Jens Thostrup Bukrinski, Åsmund Rinnan, Pernille Harris
المصدر: Molecular Pharmaceutics.
مصطلحات موضوعية: Drug Discovery, Pharmaceutical Science, Molecular Medicine
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المؤلفون: Shahid Uddin, Christin Pohl, Christopher F. van der Walle, Inas El Bialy, Jeremy P. Derrick, Andreas Tosstorff, Robin Curtis, Sujata Mahapatra, Werner Streicher, Dillen Augustijn, Aisling Roche, Alina Kulakova, Wolfgang Frieß, Åsmund Rinnan, Hristo L. Svilenov, Dierk Roessner, Lorenzo Gentiluomo, Sowmya Indrakumar, Alain Pluen, Gerhard Winter, Pernille Harris, Allan Nørgaard, Günther H.J. Peters, Maria Laura Greco, Marcello Martinez Morales, Tarik A. Khan
المصدر: Molecular Pharmaceutics
Gentiluomo, L, Svilenov, H L, Augustijn, D, El Bialy, I, Greco, M L, Vitaliyivna Kulakova, A, Indrakumar, S, Mahapatra, S, Morales, M M, Pohl, C, Roche, A, Tosstorff, A, Curtis, R, Derrick, J P, Nørgaard, A, Khan, T A, Peters, G H J, Pluen, A, Rinnan, Å, Streicher, W W, van der Walle, C F, Uddin, S, Winter, G, Roessner, D, Harris, P & Frieß, W 2020, ' Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization ', Molecular Pharmaceutics, vol. 17, no. 2, pp. 426-440 . https://doi.org/10.1021/acs.molpharmaceut.9b00852
Gentiluomo, L, Svilenov, H L, Augustijn, D, El Bialy, I, Greco, M L, Kulakova, A, Indrakumar, S, Mahapatra, S, Morales, M M, Pohl, C, Roche, A, Tosstorff, A, Curtis, R, Derrick, J P, Nørgaard, A, Khan, T A, Peters, G H J, Pluen, A, Rinnan, Å, Streicher, W W, van der Walle, C F, Uddin, S, Winter, G, Roessner, D, Harris, P & Friess, W 2020, ' Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization ', Molecular Pharmaceutics, vol. 17, no. 2, pp. 426-440 . https://doi.org/10.1021/acs.molpharmaceut.9b00852مصطلحات موضوعية: protein characterization, Computer science, Drug Storage, Stability (learning theory), Pharmaceutical Science, Serum Albumin, Human, 02 engineering and technology, Computational biology, Interferon alpha-2, Protein aggregation, 030226 pharmacology & pharmacy, Protein Aggregates, 03 medical and health sciences, 0302 clinical medicine, Protein stability, Drug Discovery, Humans, Amino Acid Sequence, Protein Unfolding, therapeutic proteins, Protein Stability, Osmolar Concentration, Transferrin, Antibodies, Monoclonal, Therapeutic protein, A protein, developability assessment, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Characterization (materials science), Solubility, Research Design, Immunoglobulin G, Molecular Medicine, protein formulation, 0210 nano-technology
وصف الملف: application/pdf
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المؤلفون: Wim Jiskoot, M. Reza Nejadnik, Inas El Bialy
المصدر: PHARMACEUTICAL RESEARCH, 34(6), 1152-1170
PHARMACEUTICAL RESEARCH
Pharmaceutical Researchمصطلحات موضوعية: 0301 basic medicine, Bone Regeneration, animal structures, Polymers, Drug Compounding, Pharmaceutical Science, 02 engineering and technology, Bioinformatics, Bone morphogenetic protein, Regenerative medicine, 03 medical and health sciences, Drug Delivery Systems, Protein stability, Drug Stability, Bone morphogenetic proteins, Protein formulation, Animals, Humans, Medicine, Effective treatment, Pharmacology (medical), Bone formation, Bone regeneration, Pharmacology, Tissue Engineering, Tissue Scaffolds, business.industry, Organic Chemistry, Growth factor, 021001 nanoscience & nanotechnology, Biotechnology, Drug Liberation, 030104 developmental biology, embryonic structures, Molecular Medicine, Delivery system, Expert Review, 0210 nano-technology, business, Site of action, Signal Transduction
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75e7533554e54df502657edc7842aea
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المؤلفون: M. Reza Nejadnik, Ahmad S. Sediq, Wim Jiskoot, Geert-Jan Witkamp, Inas El Bialy
مصطلحات موضوعية: Kinetics, Analytical chemistry, Pharmaceutical Science, Nanoparticle, Nanoparticle tracking analysis, Buffers, chemistry.chemical_compound, Nanotechnology, Technology, Pharmaceutical, Microparticle, Particle Size, Microscopy, Drop (liquid), Dextran Sulfate, Reproducibility of Results, General Medicine, Hydrogen-Ion Concentration, Polyelectrolyte, Monomer, chemistry, Models, Chemical, Immunoglobulin G, Chromatography, Gel, Nanoparticles, Particle size, Biotechnology, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920e8405c8c7687b8060d8fbe3c414c4
https://hdl.handle.net/1887/3198436 -
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المؤلفون: Günther H.J. Peters, Sowmya Indrakumar, Alexander P. Golovanov, Pernille Harris, Inas El Bialy, Werner Streicher, Matja Zalar, Allan Noergaard, Wolfgang Friess, Christin Pohl
المصدر: Molecular Pharmaceutics
Pohl, C A, Zalar, M, Bialy, I E, Indrakumar, S, Peters, G H J, Friess, W, Golovanov, A P, Streicher, W W, Noergaard, A & Harris, P 2020, ' The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide : Development of a Screening Protocol for Peptide Stability Screening ', Molecular Pharmaceutics, vol. 17, no. 9, pp. 3298-3313 . https://doi.org/10.1021/acs.molpharmaceut.0c00406مصطلحات موضوعية: protein characterization, Pore Forming Cytotoxic Proteins, Biophysics, Pharmaceutical Science, Peptide, 02 engineering and technology, Protein aggregation, 030226 pharmacology & pharmacy, protein aggregation, Protein–protein interaction, Protein Aggregates, 03 medical and health sciences, pharmaceutical screening, 0302 clinical medicine, Dynamic light scattering, Drug Discovery, medicine, Point Mutation, Thermal stability, chemistry.chemical_classification, Calorimetry, Differential Scanning, Protein Stability, Chemistry, Point mutation, protein engineering, Protein engineering, Hydrogen-Ion Concentration, Plectasin, 021001 nanoscience & nanotechnology, Dynamic Light Scattering, aggregation assessment, peptide screening, Molecular Medicine, protein−protein interactions, Peptides, 0210 nano-technology, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dacc5f6de055b16d70fda2e85673a8c
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