المؤلفون: Ingemarsdotter, CK, Poddar, S, Mercier, S, Patzel, V, Lever, AML

المساهمون: Apollo - University of Cambridge Repository

مصطلحات موضوعية: RNA trans-splicing, HSV-tk/GCV, RNA splicing, viruses, herpes simplex virus thymidine kinase-ganciclovir, HIV, exon replacement, gene therapy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8ae9e657a1424775292e5f2889e79f
https://www.repository.cam.ac.uk/handle/1810/264409

المؤلفون: D'Souza AR; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Buckingham AB; Department of Medicine, University of Cambridge, Cambridge, UK., Salasc F; Department of Medicine, University of Cambridge, Cambridge, UK., Ingemarsdotter CK; Department of Medicine, University of Cambridge, Cambridge, UK., Iaconis G; Department of Medicine, University of Cambridge, Cambridge, UK., Jarvis I; Department of Medicine, University of Cambridge, Cambridge, UK., Groom HCT; Department of Medicine, University of Cambridge, Cambridge, UK., Kenyon JC; Department of Medicine, University of Cambridge, Cambridge, UK.; Homerton College, Cambridge, UK.; Department of Microbiology and Immunology, National University of Singapore, Singapore., Lever AML; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Department of Medicine, University of Cambridge, Cambridge, UK.

المصدر: RNA biology [RNA Biol] 2021 Oct 15; Vol. 18 (sup1), pp. 148-156. Date of Electronic Publication: 2021 Sep 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Viral* , Transcription, Genetic*, RNA, Viral/*chemistry , SARS-CoV-2/*chemistry, Mutation ; Nucleic Acid Conformation ; RNA Stability ; SARS-CoV-2/classification ; SARS-CoV-2/genetics

SCR Organism: SARS-CoV-2 variants

المؤلفون: Hong EM; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK., Ingemarsdotter CK; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK., Lever AML; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK.

المصدر: British medical bulletin [Br Med Bull] 2020 Dec 15; Vol. 136 (1), pp. 4-20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376542 Publication Model: Print Cited Medium: Internet ISSN: 1471-8391 (Electronic) Linking ISSN: 00071420 NLM ISO Abbreviation: Br Med Bull Subsets: MEDLINE

مواضيع طبية MeSH: Inteins* , Trans-Splicing*, Humans ; Proteins

المؤلفون: Skittrall JP; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom., Ingemarsdotter CK; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom., Gog JR; Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Centre for Mathematical Sciences, Cambridge, United Kingdom., Lever AML; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

المصدر: PLoS computational biology [PLoS Comput Biol] 2019 Sep 23; Vol. 15 (9), pp. e1007345. Date of Electronic Publication: 2019 Sep 23 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Conserved Sequence/*genetics , Genome, Viral/*genetics , HIV-1/*genetics, Algorithms ; Codon/genetics ; Computational Biology ; HIV-1/chemistry ; HIV-1/ultrastructure ; Models, Genetic ; Nucleic Acid Conformation ; RNA, Viral/chemistry ; RNA, Viral/genetics ; RNA, Viral/ultrastructure

المؤلفون: Ingemarsdotter CK; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Box 157, Level 5, Hills Rd, Cambridge, CB2 0QQ, UK., Zeng J; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Box 157, Level 5, Hills Rd, Cambridge, CB2 0QQ, UK., Long Z; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Box 157, Level 5, Hills Rd, Cambridge, CB2 0QQ, UK., Lever AML; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Box 157, Level 5, Hills Rd, Cambridge, CB2 0QQ, UK.; Department of Medicine, National University of Singapore, Singapore, Singapore., Kenyon JC; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Box 157, Level 5, Hills Rd, Cambridge, CB2 0QQ, UK. jck33@cam.ac.uk.; Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore. jck33@cam.ac.uk.; Homerton College, University of Cambridge, Cambridge, UK. jck33@cam.ac.uk.

المصدر: Retrovirology [Retrovirology] 2018 Mar 14; Vol. 15 (1), pp. 25. Date of Electronic Publication: 2018 Mar 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101216893 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-4690 (Electronic) Linking ISSN: 17424690 NLM ISO Abbreviation: Retrovirology Subsets: MEDLINE

مواضيع طبية MeSH: Genome, Viral* , Nucleic Acid Conformation* , Virus Assembly*, HIV Infections/*virology , HIV-1/*physiology , RNA, Viral/*genetics, 5' Untranslated Regions ; Gene Products, gag/genetics ; Gene Products, gag/metabolism ; Genomic Instability ; Humans ; Protein Binding ; Proviruses/genetics ; RNA, Viral/chemistry ; Real-Time Polymerase Chain Reaction ; Viral Load ; Virus Integration ; Virus Release

المؤلفون: Ingemarsdotter CK; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., Poddar S; Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore 117545, Singapore., Mercier S; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., Patzel V; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK; Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Science Drive 2, Singapore 117545, Singapore., Lever AML; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK. Electronic address: amll1@medschl.cam.ac.uk.

المصدر: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2017 Jun 16; Vol. 7, pp. 140-154. Date of Electronic Publication: 2017 Mar 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE

المؤلفون: Tookman LA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Browne AK; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Connell CM; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Bridge G; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Ingemarsdotter CK; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Dowson S; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Shibata A; Advanced Scientific Research Leaders Development Unit, Gunma University, Maebashi, Gunma, Japan., Lockley M; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Martin SA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., McNeish IA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom. Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom. Iain.mcneish@glasgow.ac.uk.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2016 Jan; Vol. 14 (1), pp. 44-55. Date of Electronic Publication: 2015 Oct 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Homologous Recombination*, Adenoviridae/*physiology , BRCA2 Protein/*metabolism , Ovarian Neoplasms/*metabolism , Rad51 Recombinase/*metabolism, Adenoviridae/genetics ; Adenovirus E2 Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cisplatin/pharmacology ; Female ; Genetic Vectors/pharmacology ; Humans ; Oncolytic Virotherapy ; Virus Replication

المؤلفون: Browne A; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Tookman LA; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Ingemarsdotter CK; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Bouwman RD; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Pirlo K; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Wang Y; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., McNeish IA; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom. Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Lockley M; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom. m.lockley@qmul.ac.uk.

المصدر: Cancer research [Cancer Res] 2015 Jul 15; Vol. 75 (14), pp. 2811-21. Date of Electronic Publication: 2015 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Adenoviridae/*immunology , Anti-Inflammatory Agents/*pharmacology , Inflammation/*prevention & control , Integrin beta3/*metabolism , Oncolytic Virotherapy/*adverse effects , Oncolytic Viruses/*immunology , Ovarian Neoplasms/*therapy , Peptides, Cyclic/*pharmacology, Adenoviridae/drug effects ; Animals ; Anti-Inflammatory Agents/therapeutic use ; Antineoplastic Agents/immunology ; Antineoplastic Agents/therapeutic use ; Cells, Cultured ; Combined Modality Therapy ; Female ; Humans ; Integrin beta3/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Nude ; Oncolytic Viruses/drug effects ; Ovarian Neoplasms/immunology ; Ovarian Neoplasms/pathology ; Peptides, Cyclic/therapeutic use ; Xenograft Model Antitumor Assays

المؤلفون: Ingemarsdotter CK; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Tookman LA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Browne A; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Pirlo K; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Cutts R; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Chelela C; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Khurrum KF; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Leung EY; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Dowson S; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Webber L; Cancer Research UK and UCL Clinical Trials Centre, London, UK., Khan I; Cancer Research UK and UCL Clinical Trials Centre, London, UK., Ennis D; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Syed N; Division of Brain Sciences, Faculty of Medicine, Imperial College, London, UK., Crook TR; Dundee Cancer Centre, University of Dundee, Ninewells Hospital, Dundee, UK., Brenton JD; Cancer Research UK Cambridge Institute, Cambridge, UK., Lockley M; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., McNeish IA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Electronic address: iain.mcneish@glasgow.ac.uk.

المصدر: Molecular oncology [Mol Oncol] 2015 Apr; Vol. 9 (4), pp. 791-805. Date of Electronic Publication: 2014 Dec 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Adenoviridae/*metabolism , Cell Cycle Checkpoints/*drug effects , Coxsackie and Adenovirus Receptor-Like Membrane Protein/*metabolism , Drug Resistance, Neoplasm/*drug effects , Oncolytic Viruses/*metabolism , Paclitaxel/*pharmacology , Up-Regulation/*drug effects, Animals ; Cell Line, Tumor ; Cytokines/metabolism ; Female ; Histones/metabolism ; Humans ; Inflammation Mediators/metabolism ; Mice, Nude ; Ovarian Neoplasms/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Xenograft Model Antitumor Assays

المؤلفون: Salako MA; Centres for Molecular Oncology and Imaging, Institute of Cancer, Barts and The London School of Medicine and Dentistry, London, UK., Kulbe H, Ingemarsdotter CK, Pirlo KJ, Williams SL, Lockley M, Balkwill FR, McNeish IA

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2011 Mar; Vol. 19 (3), pp. 490-9. Date of Electronic Publication: 2010 Nov 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Adenoviridae*/drug effects , Adenoviridae*/immunology , Adenoviridae*/metabolism , Oncolytic Viruses*/drug effects , Oncolytic Viruses*/immunology , Oncolytic Viruses*/metabolism , Ovarian Neoplasms*/metabolism , Ovarian Neoplasms*/pathology , Ovarian Neoplasms*/therapy , Ovarian Neoplasms*/virology, Inhibitor of Apoptosis Proteins/*metabolism , Tumor Necrosis Factor-alpha/*antagonists & inhibitors , Tumor Necrosis Factor-alpha/*metabolism, Animals ; Antibodies, Monoclonal/pharmacology ; Apoptosis/drug effects ; Apoptosis/genetics ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/genetics ; Gene Knockdown Techniques ; Humans ; Infliximab ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Oncolytic Virotherapy ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Survival Analysis ; Tumor Necrosis Factor-alpha/pharmacology ; Virus Replication/drug effects ; Xenograft Model Antitumor Assays