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1دورية أكاديمية
المصدر: Pharmaceuticals, Vol 13, Iss 8, p 200 (2020)
مصطلحات موضوعية: mycophenolic acid, inosine-5′-monophosphate dehydrogenase activity, pediatric patients, HPLC method, therapeutic drug monitoring, nephrotic syndrome, Medicine, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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المؤلفون: Deviprasad R. Gollapalli, Gregory D. Cuny, Adhar C. Manna, Natalia Maltseva, Barry B. Snider, Yubo Zhang, Mohana Rao Vippila, Ann P. Lawson, Lizbeth Hedstrom, Minjia Zhang, Youngchang Kim, David M Rothstein, Shibin Chacko, Petr Kuzmic, Xingyou Wang, Andrzej Joachimiak, Ryan T Cullinane, Gyan Modi, Gary M Marqus, Ambrose L. Cheung, Judy L.M. Kotler
المصدر: ACS Infectious Diseases. 7:3062-3076
مصطلحات موضوعية: chemistry.chemical_classification, biology, medicine.drug_class, Chemistry, Antibiotics, Virulence, biology.organism_classification, medicine.disease_cause, Microbiology, Infectious Diseases, Enzyme, Staphylococcus aureus, medicine, biology.protein, Inosine-5′-monophosphate dehydrogenase, Inosine, Antibacterial activity, Bacteria, medicine.drug
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3
المؤلفون: Iulia Oancea, Andy Wu, Michael A. McGuckin, Sumaira Z. Hasnain, Rabina Giri, John D. Hooper, Veronika Schreiber, Brett C McWhinney, Julie M. Davies, Jakob Begun, Yonghua Sheng, David P. Fairlie, Saleh Y. Alabbas, Gregor Kijanka, Yaowu He, Ramya Movva, Andrew J. Lucke, Timothy H. Florin
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 33-53 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: rac1 GTP-Binding Protein, 0301 basic medicine, TGTP, thioguanine nucleotide triphosphate, TCF/LEF, T-cell factor/lymphoid enhancer factor, Colorectal cancer, MP, mercaptopurine, TGN, thioguanine nucleotides, medicine.disease_cause, Autophagy-Related Protein 7, Inflammatory bowel disease, BrdU, bromodeoxyuridine, Mice, chemistry.chemical_compound, AOM, azoxymethane, 0302 clinical medicine, GTP, guanosine triphosphate, GTPase, guanosine triphosphatase, DSS, dextran sodium sulfate, Intestinal Mucosa, Wnt Signaling Pathway, beta Catenin, Original Research, GDP, guanosine diphosphate, IBD, inflammatory bowel disease, Colon Cancer, Mercaptopurine, Dextran Sulfate, Gastroenterology, Wnt signaling pathway, Colitis, Atg7ΔIEC, intestinal epithelial cell–specific deletion of autophagy related 7 gene, Editorial, Gene Knockdown Techniques, CRC, colorectal cancer, 030211 gastroenterology & hepatology, Colon, β-Catenin, CAC, colitis-associated cancer, Azoxymethane, Mice, Transgenic, DAI, disease activity index scores, IMPDH, inosine-5′-monophosphate dehydrogenase, 03 medical and health sciences, Administration, Rectal, Anseriformes, medicine, Autophagy, Animals, Humans, lcsh:RC799-869, Thioguanine, IC50, inhibitory concentration of 50%, Hepatology, business.industry, Neuropeptides, Cancer, DMEM, Dulbecco modified Eagle medium, PBS-T, phosphate-buffered saline with 0.1% Tween-20, HCT116 Cells, medicine.disease, WT, wild-type, TG, thioguanine, 030104 developmental biology, chemistry, siRNA, small interfering RNA, Cancer research, BSA, bovine serum albumin, lcsh:Diseases of the digestive system. Gastroenterology, Caco-2 Cells, Colitis-Associated Neoplasms, business, Carcinogenesis, HPRT, hypoxanthine phosphoribosyltransferase gene
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f601ccce23a182b6171ce5a7c5598ec
http://www.sciencedirect.com/science/article/pii/S2352345X20300886 -
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المؤلفون: Ji-Long Liu, Xiao-Li Zhou, Chia-Chun Chang
المصدر: Pancreas. 50(7)
مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Fluorescent Antibody Technique, Cytoplasmic Granules, Xanthine, Endocrinology, IMP Dehydrogenase, Inosine Monophosphate, Cell Line, Tumor, Insulin-Secreting Cells, Insulin Secretion, Internal Medicine, medicine, Animals, Humans, Insulin, Inosine-5′-monophosphate dehydrogenase, Cells, Cultured, Hepatology, biology, Chemistry, Ribonucleotides, Biochemistry, biology.protein, Biocatalysis, Protein Multimerization
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf3f339ffb13c7c965f4e7fce40bd7e
https://pubmed.ncbi.nlm.nih.gov/34643616 -
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المؤلفون: Nicolas Papon, Gilles Nevez, Dorothée Quinio, Marie-Christine Moal, Claire V Hoffmann, Jean-Philippe Bouchara, Yannick Le Meur, Nathan Le Nan, Solène Le Gal
المساهمون: Groupe d'Étude des Interactions Hôte-Pathogène (GEIHP), Université d'Angers (UA), SFR UA 4208 Interactions Cellulaires et Applications Thérapeutiques (ICAT), Laboratoire de Parasitologie et Mycologiede [CHRU Brest], Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Laboratoire de Parasitologie-Mycologie (CHU d'Angers), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)
المصدر: Journal of Fungi, Vol 7, Iss 849, p 849 (2021)
Journal of Fungi
Volume 7
Issue 10
Journal of Fungi, MDPI, 2021, 7 (10), pp.849. ⟨10.3390/jof7100849⟩مصطلحات موضوعية: Microbiology (medical), QH301-705.5, [SDV]Life Sciences [q-bio], Population, selection, Plant Science, Pneumocystis pneumonia, Mycophenolic acid, Article, Pneumocystis jirovecii, Microbiology, IMPDH, 03 medical and health sciences, parasitic diseases, medicine, Inosine-5′-monophosphate dehydrogenase, Biology (General), education, Inosine, Gene, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, education.field_of_study, biology, 030306 microbiology, medicine.disease, biology.organism_classification, 3. Good health, Transplantation, biology.protein, mycophenolic acid, medicine.drug, transplantation
وصف الملف: application/pdf
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المؤلفون: Pani, Arianna, Cento, Valeria, Vismara, Chiara, Campisi, Daniela, Di Ruscio, Federica, Romandini, Alessandra, Senatore, Michele, Schenardi, Paolo Andrea, Gagliardi, Oscar Matteo, Giroldi, Simona, Zoppini, Laura, Moreno, Mauro, Corradin, Matteo, Epis, Oscar Massimiliano, Ughi, Nicola, Cuppari, Irene, Crocchiolo, Roberto, Merli, Marco, Bosio, Marco, Rossini, Silvano, Puoti, Massimo, Scaglione, Francesco
المصدر: Mayo Clinic Proceedings
مصطلحات موضوعية: CI, confidence interval, RT-PCR, reverse transcription polymerase chain reaction, VOC, variant of concern, BMI, body mass index, BAU, binding arbitrary units, MPA, mycophenolic acid, MPPDH, inosine-5’-monophosphate dehydrogenase, Original Article, MMF, mycophenolate mofetil, IQR, interquartile range
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المصدر: Pharmaceuticals
Volume 13
Issue 8
Pharmaceuticals, Vol 13, Iss 200, p 200 (2020)مصطلحات موضوعية: Adenosine monophosphate, therapeutic drug monitoring, lcsh:Medicine, lcsh:RS1-441, Pharmaceutical Science, 030204 cardiovascular system & hematology, Pharmacology, Mycophenolate, 030226 pharmacology & pharmacy, Peripheral blood mononuclear cell, Mycophenolic acid, Article, lcsh:Pharmacy and materia medica, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, medicine, pharmacodynamics, Inosine-5′-monophosphate dehydrogenase, pediatric patients, medicine.diagnostic_test, biology, nephrotic syndrome, lcsh:R, medicine.disease, Xanthosine monophosphate, stomatognathic diseases, HPLC method, chemistry, Therapeutic drug monitoring, inosine-5′-monophosphate dehydrogenase activity, biology.protein, Molecular Medicine, Nephrotic syndrome, pharmacokinetics, mycophenolic acid, medicine.drug
وصف الملف: application/pdf
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المصدر: The Journal of Antibiotics. 72:934-942
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, 030106 microbiology, Dehydrogenase, 01 natural sciences, Dithiothreitol, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, IMP Dehydrogenase, Drug Discovery, medicine, Humans, Luciferase, Enzyme Inhibitors, Inosine-5′-monophosphate dehydrogenase, Inosine, Cryptosporidium parvum, Pharmacology, Binding Sites, Antiparasitic Agents, biology, 010405 organic chemistry, biology.organism_classification, Adenosine, High-Throughput Screening Assays, 0104 chemical sciences, chemistry, biology.protein, Cyclophane, medicine.drug
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9Inhibitors of inosine 5′-monophosphate dehydrogenase as emerging new generation antimicrobial agents
المؤلفون: Sivapriya Kirubakaran, Althaf Shaik, Kapil Juvale
المصدر: Medchemcomm
مصطلحات موضوعية: Guanine, Pharmaceutical Science, Dehydrogenase, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Drug Discovery, medicine, Nucleotide, Inosine-5′-monophosphate dehydrogenase, Inosine, Pharmacology, chemistry.chemical_classification, biology, 010405 organic chemistry, Organic Chemistry, Small molecule, 0104 chemical sciences, De novo synthesis, Chemistry, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, biology.protein, Molecular Medicine, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1300e671d50123a6cf06eb8f4c97f219
https://doi.org/10.1039/c9md00179d -
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المؤلفون: Jackeline de Lima Zanella, Maxuel O. Andrade, Artur T. Cordeiro, Celso Eduardo Benedetti, Gustavo Fernando Mercaldi
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Druggability, Sequence Homology, Phenylenediamines, DMSO, dimethyl sulfoxide, Xanthomonas campestris, Biochemistry, MetRS, AMR, antimicrobial resistance, EcMetRS, Escherichia coli MetRS, Substrate Specificity, chemistry.chemical_compound, RNA, Transfer, EcLeuRS, E. coli Leucyl-tRNA synthetase, Xanthomonas citri, diaryldiamines, chemistry.chemical_classification, CP, connective polypeptide, Tm, melting temperature, biology, ITC, isothermal titration calorimetry, ScAMD, Saccharomyces cerevisiae AMP deaminase, REP8839, Amino acid, Transfer RNA, Research Article, MetRS, methionine-tRNA synthetase, AaRS, aminoacyl-tRNA synthetase, Methionine-tRNA Ligase, DSF, differential scanning fluorimetry, AaMetRS, Aquifex aeolicus MetRS, 03 medical and health sciences, Bacterial Proteins, A76, adenosine 76, PDB, Protein Data Bank, methionine-tRNA synthetase, Amino Acid Sequence, antimicrobial resistance, Binding site, Molecular Biology, XcMetRS, Xanthomonas citri MetRS, Methionine, Binding Sites, XcΔMetRS, truncated version of XcMetRS lacking the C-terminal extension domain, 030102 biochemistry & molecular biology, Aminoacyl tRNA synthetase, L-Met, L-methionine, Cell Biology, biology.organism_classification, CjIMPDH, Campylobacter jejuni Inosine-5'-monophosphate dehydrogenase, Bederocin, LNBio/CNPEM, Brazilian Bioscience National Laboratory/Brazilian Centre for Research in Energy and Materials, 030104 developmental biology, Enzyme, chemistry, Protein Biosynthesis, REP3123, Bacteria
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbdd329108a3856fe29326d32428f16
https://pubmed.ncbi.nlm.nih.gov/33857480