-
1
المؤلفون: Thore, Sophia, Dyachok, Oleg, Gylfe, Erik, Tengholm, Anders
المصدر: Journal of Cell Science. 118(Pt 19):4463-4471
مصطلحات موضوعية: Animals, Boron Compounds/metabolism, Ca(2+)-Transporting ATPase/antagonists & inhibitors/metabolism, Calcium/*metabolism, Calcium Channel Blockers/metabolism, Calcium Channels/metabolism, Cells, Cultured, Diazoxide/metabolism, Enzyme Activation, Feedback, Biochemical, Green Fluorescent Proteins/genetics/metabolism, Inositol 1, 5-Trisphosphate/metabolism, Insulin/*metabolism, Insulin-Secreting Cells/cytology/*metabolism, Isoenzymes/genetics/*metabolism, Lanthanum/metabolism, Mice, Microscopy, Fluorescence/methods, Phospholipase C/genetics/*metabolism, Recombinant Fusion Proteins/genetics/metabolism, Research Support, Non-U.S. Gov't, Signal Transduction/*physiology, MEDICINE, Morphology, cell biology, pathology, Cell biology, MEDICIN, Morfologi, cellbiologi, patologi, Cellbiologi, medicinsk cellbiologi, Medical Cell Biology
وصف الملف: electronic
URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-79778
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16159958&dopt=Citation
https://uu.diva-portal.org/smash/get/diva2:107691/FULLTEXT01.pdf -
2
المؤلفون: Golec, Ewelina, Rosberg, Rebecca, Zhang, Enming, Renström, Erik, Blom, Anna M, King, Ben C
المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology EXODIAB: Excellence of Diabetes Research in Sweden NanoLund: Centre for Nanoscience BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation. 33(11):12425-12434
مصطلحات موضوعية: Animals, CD59 Antigens/genetics, CHO Cells, Cricetulus, Cytosol/metabolism, Exocytosis, Insulin/genetics, Insulin Secretion, Insulin-Secreting Cells/cytology, Oligosaccharides/genetics, Rats, SNARE Proteins/genetics, Medicin och hälsovetenskap, Klinisk medicin, Endokrinologi och diabetes, Medical and Health Sciences, Clinical Medicine, Endocrinology and Diabetes
-
3
المؤلفون: Mathie Tenenbaum, Amar Abderrahmani, Amélie Bonnefond, Stéphane Dalle, Julien Bourry, Valery Gmyr, Philippe Froguel, Valérie Pawlowski, Nicole Beeler, Valérie Plaisance, Raphael Boutry, Hélène Ezanno, Clara Sanchez-Parra, Cécile Jacovetti, Romano Regazzi, Gianni Pasquetti, François Pattou, Syu-Ichi Hirai, Julie Kerr-Conte
المساهمون: Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (EGENODIA (GI3M)), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 (IEMN), Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA), Université catholique de Lille (UCL)-Université catholique de Lille (UCL), NanoBioInterfaces - IEMN (NBI - IEMN), Université catholique de Lille (UCL)-Université catholique de Lille (UCL)-Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-JUNIA (JUNIA), Université de Lausanne = University of Lausanne (UNIL), Recherche translationnelle sur le diabète - U 1190 (RTD), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Wakayama University, Imperial College London, This work was supported by grants from 'Société Francophone du Diabète (SFD)', 'European Genomic Institute for Diabetes' (E.G.I.D., ANR-10-LABEX-46) and European Commission, European Research Council (GEPIDIAB 294785 to P.F.), and by a grant from the Swiss National Science Foundation (310030-169480 to RR). Human islets were provided by the European Consortium for Islet Transplantation, funded by the Juvenile Diabetes Research Foundation International., ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), European Project: 294785,EC:FP7:ERC,ERC-2011-ADG_20110310,GEPIDIAB(2012), Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (GI3M), Université de Lausanne (UNIL), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 2021, 78 (1), pp.287-298. ⟨10.1007/s00018-020-03499-7⟩
Cellular and molecular life sciences, vol. 78, no. 1, pp. 287-298
Cellular and Molecular Life Sciences, Springer Verlag, 2021, 78 (1), pp.287-298. ⟨10.1007/s00018-020-03499-7⟩مصطلحات موضوعية: MAPK/ERK pathway, endocrine system, Biology, Mapk, Beta-cell mass, Transcriptome, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, [SPI]Engineering Sciences [physics], Mitogen-Activated Protein Kinase 10, Pregnancy, Insulin-Secreting Cells, Animals, Cell Proliferation/drug effects, Cyclin D1/genetics, Cyclin D1/metabolism, Cyclin D2/genetics, Cyclin D2/metabolism, Female, Glucose/pharmacology, Humans, Insulin/metabolism, Insulin-Secreting Cells/cytology, Insulin-Secreting Cells/metabolism, MAP Kinase Kinase Kinases/antagonists & inhibitors, MAP Kinase Kinase Kinases/genetics, MAP Kinase Kinase Kinases/metabolism, Mice, Inbred C57BL, Mitogen-Activated Protein Kinase 10/antagonists & inhibitors, Mitogen-Activated Protein Kinase 10/genetics, Mitogen-Activated Protein Kinase 10/metabolism, Obesity/metabolism, Obesity/pathology, Pancreas/growth & development, Pancreas/metabolism, RNA Interference, RNA, Small Interfering/metabolism, Rats, Signal Transduction/drug effects, Obesity, Postnatal development, Gene silencing, Cyclin D2, Insulin, Cyclin D1, RNA, Small Interfering, Molecular Biology, Pancreas, Cyclin, Cell Proliferation, Pharmacology, Serine/threonine-specific protein kinase, 0303 health sciences, geography, geography.geographical_feature_category, Kinase, 030302 biochemistry & molecular biology, Cell Biology, Islet, MAP Kinase Kinase Kinases, Cell biology, Glucose, Molecular Medicine, Signal transduction, Signal Transduction
وصف الملف: application/pdf
-
4
المؤلفون: Perez-Frances, Marta, van Gurp, Léon, Abate, Maria Valentina, Cigliola, Valentina, Furuyama, Kenichiro, Bru-Tari, Eva, Oropeza, Daniel, Carreaux, Taïna, Fujitani, Yoshio, Thorel, Fabrizio, Herrera, Pedro L.
المصدر: Nature Communications, Vol. 12, No 1 (2021) P. 4458
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)مصطلحات موضوعية: Male, Cell biology, Cell Lineage / genetics, Pancreas / growth & development, Pancreatic Polypeptide-Secreting Cells / cytology, Science, Mice, Transgenic, Insulin-Secreting Cells / cytology, Article, Pancreas / embryology, Islets of Langerhans, Mice, ddc:590, Pregnancy, Blood Glucose / metabolism, Pancreatic Polypeptide-Secreting Cells / metabolism, Animals, Humans, Pancreas / cytology, ddc:576.5, Gene Knock-In Techniques, RNA-Seq, Pancreatic Polypeptide / genetics, Insulin-Secreting Cells / metabolism, Protein Precursors / metabolism, Diabetes, Body Weight, Pancreatic Polypeptide-Secreting Cells / classification, Insulin-Secreting Cells / classification, Pancreatic Polypeptide / metabolism, Pancreatic Polypeptide / deficiency, Insulin / biosynthesis, Female
-
5رسالة جامعية
المؤلفون: Hörnblad, Andreas
مصطلحات موضوعية: Morphogenesis -- physiology, Pancreas -- embryology, Pancreas -- pathology, Spleen -- embryology, Computational biology -- methods, Insulin-secreting cells -- cytology, Insulin-secreting cells -- pathology, Islets of Langerhans -- anatomy & histology, Tomography, optical -- methods, Diabetes mellitus, experimental -- pathology, Diabetes mellitus, type 1 -- pathology, Type 1 diabetes, β-cell mass, Tertiary lymphoid organs, Biomedical imaging, Optical projection, Tomography, Pancreas development, Gastric lobe, Spleen development
Degree: Diss. (sammanfattning) Umeå : Umeå universitet, 2012
-
6
المؤلفون: Esther Lizárraga-Mollinedo, Jean Valéry Turatsinze, Maria Inês Alvelos, Olatz Villate, Jonàs Juan-Mateu, Piero Marchetti, Marco Bugliani, Fabio Arturo Grieco, Laura Marroquí, Decio L. Eizirik
المصدر: Diabetes
Diabetes (New York, N.Y.)مصطلحات موضوعية: 0301 basic medicine, Endocrinology, Diabetes and Metabolism, Apoptosis, Phosphoproteins -- antagonists & inhibitors -- chemistry -- genetics -- metabolism, 0302 clinical medicine, Mitochondria -- enzymology -- metabolism, RNA interference, Insulin-Secreting Cells, Insulin Secretion, Insulin -- secretion, Insulin, Phosphorylation, Cells, Cultured, bcl-2-Associated X Protein, Regulation of gene expression, Bcl-2-Like Protein 11, Serine-Arginine Splicing Factors, Sciences bio-médicales et agricoles, Endoplasmic Reticulum Stress, Mitochondria, Cell biology, 030220 oncology & carcinogenesis, RNA splicing, RNA Interference, Bcl-2-Like Protein 11 -- genetics -- metabolism, Cell Survival, MAP Kinase Signaling System, Insulin-Secreting Cells -- cytology -- metabolism -- secretion, Biology, bcl-2-Associated X Protein -- genetics -- metabolism, Cell Line, 03 medical and health sciences, Splicing factor, Internal Medicine, Humans, Protein Interaction Domains and Motifs, Gene, Gene Expression Profiling, Endoplasmic reticulum, Alternative splicing, Phosphoproteins, Gene expression profiling, Alternative Splicing, 030104 developmental biology, Gene Expression Regulation, Islet Studies, Serine-Arginine Splicing Factors -- antagonists & inhibitors -- chemistry -- genetics -- metabolism, Protein Processing, Post-Translational
وصف الملف: 2 full-text file(s): application/pdf; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cb56e6f8858e92b787f798306a9c39
https://doi.org/10.2337/db17-0736 -
7رسالة جامعية
المؤلفون: Selander, Lars
مصطلحات موضوعية: Endocrine system -- metabolism, Insulin-secreting cells -- cytology, Pancreas -- metabolism, Pancreas -- embryology, Stem cells -- cytology
Degree: Diss. (sammanfattning) Umeå : Umeå universitet, 2009
-
8
المؤلفون: Simranjeet Kaur, Thomas Mandrup-Poulsen, Peter de Hemmer Horskjær, Christine Bruun, Joachim Størling, Flemming Pociot, Tina Fløyel, Anna L. Vestergaard, Romano Regazzi, Claus Heiner Bang-Berthelsen, Lukas Adrian Berchtold, Jonathan Lucien Stahl, Lisa Christen, Farzaneh Taheri Sotudeh, Klaus Stensgaard Frederiksen, Frida Greek Kofod
المصدر: Vestergaard, A L, Bang-Berthelsen, C H, Floyel, T, Stahl, J L, Christen, L, Sotudeh, F T, Horskjaer, P D H, Frederiksen, K S, Kofod, F G, Bruun, C, Berchtold, L A, Storling, J, Regazzi, R, Kaur, S, Pociot, F & Mandrup-Poulsen, T 2018, ' MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage ', PLOS ONE, vol. 13, no. 9, e0203713, pp. 1-22 . https://doi.org/10.1371/journal.pone.0203713
PloS one, vol. 13, no. 9, pp. e0203713
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0203713 (2018)مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, Microarrays, medicine.medical_treatment, lcsh:Medicine, Gene Expression, Apoptosis, Pathology and Laboratory Medicine, Biochemistry, Diabetes mellitus genetics, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Immune Physiology, Insulin-Secreting Cells, Medicine and Health Sciences, lcsh:Science, Immune Response, Regulation of gene expression, Adult, Animals, Cell Line, Cytokines/metabolism, Diabetes Mellitus/genetics, Diabetes Mellitus/metabolism, Female, Gene Expression Regulation, Histone Deacetylase Inhibitors/pharmacology, Humans, Insulin-Secreting Cells/cytology, Insulin-Secreting Cells/physiology, Islets of Langerhans/metabolism, MicroRNAs/physiology, Middle Aged, NF-kappa B/genetics, NF-kappa B/metabolism, Rats, Rats, Wistar, Innate Immune System, Multidisciplinary, Cell Death, Chemistry, NF-kappa B, Transfection, Enzymes, TNF receptor associated factor, Cytokine, Bioassays and Physiological Analysis, Cell Processes, 030220 oncology & carcinogenesis, Cytokines, medicine.symptom, Oxidoreductases, Luciferase, Research Article, Endocrine Disorders, Immunology, Inflammation, Research and Analysis Methods, 03 medical and health sciences, Islets of Langerhans, Signs and Symptoms, Diagnostic Medicine, medicine, Diabetes Mellitus, Genetics, Givinostat, Molecular Biology Techniques, Molecular Biology, lcsh:R, Biology and Life Sciences, Proteins, Cell Biology, Molecular Development, Histone Deacetylase Inhibitors, MicroRNAs, 030104 developmental biology, Immune System, Metabolic Disorders, Cancer research, Enzymology, lcsh:Q, Histone deacetylase, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb30b397012919ce28ea03bcc811726
https://curis.ku.dk/ws/files/210015667/journal.pone.0203713.pdf -
9
المؤلفون: Harry Heimberg, Gunter Leuckx, Eelco J.P. de Koning, Yves Heremans, Yannick Verdonck, Carlo Heirman, Nico De Leu, Willem Staels, Kris Thielemans, Sofie De Groef, Luc Baeyens, Conny Gysemans
المساهمون: Pathology/molecular and cellular medicine, Beta Cell Neogenesis, Faculty of Medicine and Pharmacy, Faculty of Sciences and Bioengineering Sciences, Laboratory of Molecullar and Cellular Therapy, Basic (bio-) Medical Sciences, Physiology, Immunomodulation in Chronic Inflammatory Diseases, Hematology, Medical Oncology, Pathologic Biochemistry and Physiology, Clinical sciences, Internal Medicine, Hubrecht Institute for Developmental Biology and Stem Cell Research
المصدر: Diabetologia
Diabetologia, 61(8), 1804-1810. Springer Verlag GmbH
Diabetologia, 61(8), 1804-1810مصطلحات موضوعية: Vascular Endothelial Growth Factor A, RNA, Messenger/genetics, 0301 basic medicine, medicine.medical_treatment, VEGF receptors, Endocrinology, Diabetes and Metabolism, Islets of Langerhans Transplantation, Cell therapy, Insulin-Secreting Cells/cytology, 0302 clinical medicine, Insulin-Secreting Cells, Insulin, Medicine, Mrna transfection, Gene delivery, Islet transplantation, Pancreatic beta cell, geography.geographical_feature_category, biology, Messenger RNA, Diabetes, Transfection, Islet, 3. Good health, Islets of Langerhans/cytology, Vascular endothelial growth factor A, Beta cell, Graft revascularisation, VEGFA, mice, Insulin/metabolism, Cell Survival, Neovascularization, Physiologic, RNA delivery, 030209 endocrinology & metabolism, Revascularization, Viral vector, Vascular Endothelial Growth Factor A/genetics, Andrology, Islets of Langerhans, 03 medical and health sciences, Internal Medicine, Humans, Animals, RNA, Messenger, Physiologic, Neovascularization, geography, business.industry, Transplantation, 030104 developmental biology, Cancer research, biology.protein, RNA, Messenger/genetics, business
-
10
المؤلفون: Mark C. Poznansky, Thierry Berney, Luhan Yang, Jon S. Odorico, Melanie L. Graham, Julia L. Greenstein, Lorenzo Piemonti, Bart O. Roep, Melissa K. Carpenter, Kevin A. D'Amour, Chad A. Cowan, Jose Oberholzer, C Ricordi, Alice A. Tomei, James F. Markmann, Ludovic Vallier, Albert Hwa, Dieter Egli, Giuseppe Orlando, Ali Naji, Michael R. Rickels, Giovanni Migliaccio, Shane T. Grey, Bernhard J. Hering, Thomas W.H. Kay, Dale L. Greiner, Ann Jensen Adams, Cristina Nostro, Barbara Ludwig, Qizhi Tang, Alireza Rezania, Daniel Pipeleers, Danwei Huangfu, Uri Ben-David, Douglas A. Melton, Daniel G. Anderson
المساهمون: Pathology/molecular and cellular medicine, Vriendenkring VUB, Diabetes Pathology & Therapy, Odorico, Jon, Markmann, Jame, Melton, Dougla, Greenstein, Julia, Hwa, Albert, Nostro, Cristina, Rezania, Alireza, Oberholzer, Jose, Pipeleers, Daniel, Yang, Luhan, Cowan, Chad, Huangfu, Danwei, Egli, Dieter, Ben-David, Uri, Vallier, Ludovic, Grey, Shane T, Tang, Qizhi, Roep, Bart, Ricordi, Camilo, Naji, Ali, Orlando, Giuseppe, Anderson, Daniel G, Poznansky, Mark, Ludwig, Barbara, Tomei, Alice, Greiner, Dale L, Graham, Melanie, Carpenter, Melissa, Migliaccio, Giovanni, D'Amour, Kevin, Hering, Bernhard, Piemonti, Lorenzo, Berney, Thierry, Rickels, Mike, Kay, Thoma, Adams, Ann
المصدر: Transplantation
Transplantation (2018)
Transplantation, 102(8), 1223-1229
Transplantation, vol 102, iss 8مصطلحات موضوعية: 0301 basic medicine, Pancreas/cytology, medicine.medical_treatment, Cellular differentiation, Islets of Langerhans Transplantation, Regenerative Medicine, Medical and Health Sciences, Insulin-Secreting Cells/cytology, Stem Cell Research - Nonembryonic - Human, Insulin-Secreting Cells, Induced pluripotent stem cell, Gene Editing, ddc:617, Pancreas Transplantation/methods, Stem Cells, Diabetes, Immunosuppression, Cell Differentiation, Tissue Donors, 3. Good health, Stem Cell Research - Nonembryonic - Non-Human, Pancreas Transplantation, Development of treatments and therapeutic interventions, Beta cell, Stem cell, Type 1, Pluripotent Stem Cells, medicine.medical_specialty, Stem Cell Transplantation/methods, Pancreas transplantation, Autoimmune Disease, Article, 03 medical and health sciences, Diabetes mellitus, Diabetes Mellitus, medicine, Immune Tolerance, Animals, Humans, Muscle, Skeletal, Intensive care medicine, Pancreas, Metabolic and endocrine, Transplantation, 5.2 Cellular and gene therapies, business.industry, Pluripotent Stem Cells/cytology, Congresses as Topic, Stem Cell Research, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Surgery, Diabetes Mellitus, Type 1/therapy, business, Stem Cell Transplantation, Boston
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f5df07c7122eecb6ecd7e2a579770e
https://hdl.handle.net/1887/87310
Find this article in full text from Springer Verlag.