المؤلفون: Liu X; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Wang W; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Weiwei.Wang@UTSouthwestern.edu.

المصدر: Nature communications [Nat Commun] 2023 Oct 11; Vol. 14 (1), pp. 6377. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Glycine*/metabolism , Cysteine Loop Ligand-Gated Ion Channel Receptors*/chemistry , Cysteine Loop Ligand-Gated Ion Channel Receptors*/metabolism, Humans ; Ion Channel Gating/physiology ; Synaptic Transmission ; Glycine

المؤلفون: Kim ED; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA., Wu X; Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA., Lee S; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA., Tibbs GR; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA., Cunningham KP; Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA.; School of Life Sciences, University of Westminster, London, UK., Di Zanni E; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA., Perez ME; Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA., Goldstein PA; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA., Accardi A; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA.; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA., Larsson HP; Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA. peter.larsson@liu.se.; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden. peter.larsson@liu.se., Nimigean CM; Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA. crn2002@med.cornell.edu.; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA. crn2002@med.cornell.edu.

المصدر: Nature [Nature] 2024 Aug; Vol. 632 (8024), pp. 451-459. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Epilepsy*/drug therapy , Epilepsy*/genetics , Epilepsy*/metabolism , Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels*/antagonists & inhibitors , Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels*/chemistry , Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels*/genetics , Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels*/metabolism , Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels*/ultrastructure , Ion Channel Gating*/drug effects , Ion Channel Gating*/genetics , Mutation* , Potassium Channels*/chemistry , Potassium Channels*/genetics , Potassium Channels*/metabolism , Potassium Channels*/ultrastructure , Propofol*/pharmacology , Propofol*/chemistry, Humans ; Binding Sites ; Cryoelectron Microscopy ; Electrophysiology ; HEK293 Cells ; Methionine/genetics ; Methionine/metabolism ; Models, Molecular ; Movement/drug effects ; Phenylalanine/genetics ; Phenylalanine/metabolism ; Polymorphism, Genetic

المؤلفون: Itoh M; Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan., Piot L; Institut de Biologie de l'Ecole Normale Supérieure, Ecole Normale Supérieure, Université Paris Sciences & Lettres, CNRS, INSERM, Paris F-75005, France., Mony L; Institut de Biologie de l'Ecole Normale Supérieure, Ecole Normale Supérieure, Université Paris Sciences & Lettres, CNRS, INSERM, Paris F-75005, France., Paoletti P; Institut de Biologie de l'Ecole Normale Supérieure, Ecole Normale Supérieure, Université Paris Sciences & Lettres, CNRS, INSERM, Paris F-75005, France., Yuzaki M; Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 30; Vol. 121 (31), pp. e2406655121. Date of Electronic Publication: 2024 Jul 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channel Gating*/drug effects , Receptors, Glutamate*/metabolism, Animals ; Humans ; Mice ; Glycine/metabolism ; HEK293 Cells ; Ligand-Gated Ion Channels/metabolism ; Ligand-Gated Ion Channels/genetics ; Ligands ; Serine/metabolism

المؤلفون: Miller JM; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania., Carlson AE; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: acarlson@pitt.edu.

المصدر: Biophysical journal [Biophys J] 2024 Aug 20; Vol. 123 (16), pp. 2358-2359. Date of Electronic Publication: 2024 Jul 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channel Gating* , Amino Acids*/chemistry , Amino Acids*/metabolism, Humans ; Animals ; HEK293 Cells ; ERG1 Potassium Channel/metabolism ; ERG1 Potassium Channel/chemistry ; Ether-A-Go-Go Potassium Channels/metabolism ; Ether-A-Go-Go Potassium Channels/chemistry

المؤلفون: Codding SJ; Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland., Trudeau MC; Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland. Electronic address: mtrudeau@som.umaryland.edu.

المصدر: Biophysical journal [Biophys J] 2024 Aug 20; Vol. 123 (16), pp. 2392-2405. Date of Electronic Publication: 2024 May 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

مواضيع طبية MeSH: Ultraviolet Rays* , Ion Channel Gating*/radiation effects , Protein Domains*, Humans ; Phenylalanine/chemistry ; Phenylalanine/metabolism ; Phenylalanine/analogs & derivatives ; HEK293 Cells ; ERG1 Potassium Channel/metabolism ; ERG1 Potassium Channel/chemistry ; ERG1 Potassium Channel/genetics ; Photochemical Processes ; Benzophenones

المؤلفون: Chou TH; W.M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Epstein M; W.M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Fritzemeier RG; Department of Chemistry, Emory University, Atlanta, GA, USA., Akins NS; Department of Chemistry, Emory University, Atlanta, GA, USA., Paladugu S; Department of Chemistry, Emory University, Atlanta, GA, USA., Ullman EZ; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, USA., Liotta DC; Department of Chemistry, Emory University, Atlanta, GA, USA., Traynelis SF; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, USA.; Neurodegenerative Disease Center, Emory University School of Medicine, Atlanta, GA, USA., Furukawa H; W.M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. furukawa@cshl.edu.

المصدر: Nature [Nature] 2024 Aug; Vol. 632 (8023), pp. 209-217. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Glutamic Acid*/metabolism , Glycine*/metabolism , Ion Channel Gating* , Receptors, N-Methyl-D-Aspartate*/chemistry , Receptors, N-Methyl-D-Aspartate*/metabolism , Receptors, N-Methyl-D-Aspartate*/ultrastructure, Animals ; Rats ; Allosteric Regulation ; Cryoelectron Microscopy ; Ligands ; Models, Molecular ; Oocytes/metabolism ; Protein Domains ; Protein Multimerization ; Protein Subunits/metabolism ; Protein Subunits/chemistry ; Rotation ; Xenopus laevis

المؤلفون: Kwon HC; Biophysics Graduate Program, University of California, Davis, CA 95618, USA., Fairclough RH; Biophysics Graduate Program, University of California, Davis, CA 95618, USA.; Department of Neurology, University of California, Davis, CA 95618, USA., Chen TY; Biophysics Graduate Program, University of California, Davis, CA 95618, USA.; Department of Neurology, University of California, Davis, CA 95618, USA.; Center for Neuroscience, University of California, 1544 Newton Court, Davis, CA 95618, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 16; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Protons* , Chloride Channels*/metabolism , Chloride Channels*/antagonists & inhibitors , Chloride Channels*/chemistry , Chloride Channels*/genetics , Ion Channel Gating*/drug effects, Animals ; Mutation ; Kinetics

المؤلفون: Lin JL; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St. Louis, Missouri; Graduate Program in Biochemistry, Biophysics, & Structural Biology, Washington University School of Medicine, St. Louis, Missouri., Chang Y; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St. Louis, Missouri., Tewari D; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St. Louis, Missouri., Cowgill J; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St. Louis, Missouri., Chanda B; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St. Louis, Missouri. Electronic address: bchanda@wustl.edu.

المصدر: Biophysical journal [Biophys J] 2024 Jul 16; Vol. 123 (14), pp. 2176-2184. Date of Electronic Publication: 2024 Apr 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channel Gating* , Protein Domains*, Animals ; Amino Acid Sequence ; Humans ; Cyclic Nucleotide-Gated Cation Channels/metabolism ; Cyclic Nucleotide-Gated Cation Channels/chemistry ; Cyclic Nucleotide-Gated Cation Channels/genetics

المؤلفون: Nors JW; Department of Neuroscience, University of Texas at Austin, Austin, Texas; Department of Molecular and Cellular Physiology, Stanford University, Stanford, California., Endres Z; Department of Neuroscience, University of Texas at Austin, Austin, Texas., Goldschen-Ohm MP; Department of Neuroscience, University of Texas at Austin, Austin, Texas. Electronic address: marcel.goldschen-ohm@austin.utexas.edu.

المصدر: Biophysical journal [Biophys J] 2024 Jul 16; Vol. 123 (14), pp. 2085-2096. Date of Electronic Publication: 2024 Feb 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, GABA-A*/metabolism , Receptors, GABA-A*/chemistry , Receptors, GABA-A*/genetics , Diazepam*/pharmacology , Diazepam*/chemistry , Ion Channel Gating*/drug effects , Protein Subunits*/metabolism , Protein Subunits*/chemistry , Protein Subunits*/genetics, Humans ; Animals ; Mutation ; HEK293 Cells

المؤلفون: Todorovic J; Department of Neuroscience, The University of Texas, Austin, Texas., Swapna I; Department of Neuroscience, The University of Texas, Austin, Texas., Suma A; Institute for Computational Molecular Science, College of Science and Technology & Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania., Carnevale V; Institute for Computational Molecular Science, College of Science and Technology & Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania., Zakon H; Department of Neuroscience, The University of Texas, Austin, Texas; Department of Integrative Biology, The University of Texas, Austin, Texas. Electronic address: h.zakon@austin.utexas.edu.

المصدر: Biophysical journal [Biophys J] 2024 Jul 16; Vol. 123 (14), pp. 2097-2109. Date of Electronic Publication: 2024 Mar 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channel Gating* , Molecular Dynamics Simulation*, Animals ; Electric Fish/physiology ; Amino Acid Sequence ; Shaker Superfamily of Potassium Channels/chemistry ; Shaker Superfamily of Potassium Channels/metabolism