يعرض 1 - 10 نتائج من 40 نتيجة بحث عن '"Irene, Hallyburton"', وقت الاستعلام: 1.09s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Screening a protein kinase inhibitor library against Plasmodium falciparum

    المؤلفون: Irene Hallyburton, Raffaella Grimaldi, Andrew Woodland, Beatriz Baragaña, Torsten Luksch, Daniel Spinks, Daniel James, Didier Leroy, David Waterson, Alan H. Fairlamb, Paul G. Wyatt, Ian H. Gilbert, Julie A. Frearson

    المصدر: Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017)

    مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

    وصف الملف: electronic resource

    Relation: http://link.springer.com/article/10.1186/s12936-017-2085-4; https://doaj.org/toc/1475-2875

    URL الوصول: https://doaj.org/article/566b9ef7b74a4082b406a4a2a9e0d020

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  2. 2
    Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase

    المؤلفون: Rachel Milne, Natalie Wiedemar, Victoriano Corpas-Lopez, Eoin Moynihan, Richard J. Wall, Alice Dawson, David A. Robinson, Sharon M. Shepherd, Robert J. Smith, Irene Hallyburton, John M. Post, Karen Dowers, Leah S. Torrie, Ian H. Gilbert, Beatriz Baragaña, Stephen Patterson, Susan Wyllie

    المصدر: ACS Infectious Diseases. 8:1962-1974

    مصطلحات موضوعية: Infectious Diseases

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::01ffb3cb31c0aa59ce11128553ce7e12
    https://doi.org/10.1021/acsinfecdis.2c00364

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  3. 3
    دورية أكاديمية
    Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

    المؤلفون: Alice E. Williamson, Paul M. Ylioja, Murray N. Robertson, Yevgeniya Antonova-Koch, Vicky Avery, Jonathan B. Baell, Harikrishna Batchu, Sanjay Batra, Jeremy N. Burrows, Soumya Bhattacharyya, Felix Calderon, Susan A. Charman, Julie Clark, Benigno Crespo, Matin Dean, Stefan L. Debbert, Michael Delves, Adelaide S. M. Dennis, Frederik Deroose, Sandra Duffy, Sabine Fletcher, Guri Giaever, Irene Hallyburton, Francisco-Javier Gamo, Marinella Gebbia, R. Kiplin Guy, Zoe Hungerford, Kiaran Kirk, Maria J. Lafuente-Monasterio, Anna Lee, Stephan Meister, Corey Nislow, John P. Overington, George Papadatos, Luc Patiny, James Pham, Stuart A. Ralph, Andrea Ruecker, Eileen Ryan, Christopher Southan, Kumkum Srivastava, Chris Swain, Matthew J. Tarnowski, Patrick Thomson, Peter Turner, Iain M. Wallace, Timothy N. C. Wells, Karen White, Laura White, Paul Willis, Elizabeth A. Winzeler, Sergio Wittlin, Matthew H. Todd

    المصدر: ACS Central Science, Vol 2, Iss 10, Pp 687-701 (2016)

    مصطلحات موضوعية: Chemistry, QD1-999

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2374-7943; https://doaj.org/toc/2374-7951

    URL الوصول: https://doaj.org/article/389f0d71ee2a4fb79f8bb1da8028bfae

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  4. 4
    Preparation, biological evaluation and QSAR analysis of urea substituted 2,4-diamino-pyrimidine anti-malarials

    المؤلفون: Borvornwat Toviwek, Jennifer Riley, Nicole Mutter, Mark Anderson, Lauren Webster, Irene Hallyburton, Duangkamol Gleeson, Kevin D. Read, M. Paul Gleeson

    المصدر: RSC Medicinal Chemistry. 13:1587-1604

    مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Biochemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4472d1cb56c89b9002f50a2216a2b193
    https://doi.org/10.1039/d2md00218c

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  5. 5
    Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as Pf eEF2

    المؤلفون: Benoît Laleu, Kelly Rubiano, Tomas Yeo, Irene Hallyburton, Mark Anderson, Benigno Crespo‐Fernandez, Francisco‐Javier Gamo, Yevgeniya Antonova‐Koch, Pamela Orjuela‐Sanchez, Sergio Wittlin, Gouranga P. Jana, Bikash C. Maity, Elodie Chenu, James Duffy, Peter Sjö, David Waterson, Elizabeth Winzeler, Eric Guantai, David A. Fidock, Thomas G. Hansson

    المصدر: ChemMedChem. 17

    مصطلحات موضوعية: Pharmacology, Antimalarials, Plasmodium falciparum, Organic Chemistry, Drug Discovery, Humans, Molecular Medicine, Malaria, Falciparum, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry, Malaria

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c965027fb72c128405e0f15eef30b36
    https://doi.org/10.1002/cmdc.202200393

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  6. 6
    Escaping from Flatland: Antimalarial Activity of sp3-Rich Bridged Pyrrolidine Derivatives

    المؤلفون: Michael Robertson-Ralph, Mark G. Anderson, Corentin Bellanger, Brian Cox, Benoît Laleu, Luke D. Elliott, James Duffy, Jessica Hurcum, Christopher J. Swain, Victor Zdorichenko, Irene Hallyburton, Kevin I. Booker-Milburn, Stephen J. Bishop

    المصدر: ACS Medicinal Chemistry Letters. 11:2497-2503

    مصطلحات موضوعية: 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, 010405 organic chemistry, Drug discovery, Organic Chemistry, Drug Discovery, 01 natural sciences, Biochemistry, Combinatorial chemistry, Pyrrolidine, 0104 chemical sciences

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::750b0d9daefbce88109fcc1239babaa7
    https://doi.org/10.1021/acsmedchemlett.0c00486

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  7. 7
    Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials

    المؤلفون: Edwin G Tse, Irene Hallyburton, Mark G. Anderson, Sevan D. Houston, Gregory S. Walker, R. Scott Obach, Matthew H. Todd, G. Paul Savage, Craig M. Williams, Louis M. Rendina, Raman Sharma

    المصدر: Journal of Medicinal Chemistry

    مصطلحات موضوعية: Boron Compounds, Cell Survival, Chemistry, Pharmaceutical, Plasmodium falciparum, malaria, norbornene, Common method, bicyclo[1.1.1]pentane, 0305 Organic Chemistry, 01 natural sciences, antimalarials, carborane, Antimalarials, Bridged Bicyclo Compounds, 03 medical and health sciences, chemistry.chemical_compound, cubane, Biological property, Drug Discovery, bioisosteres, 0302 Inorganic Chemistry, Humans, Molecule, 030304 developmental biology, 0303 health sciences, 0304 Medicinal and Biomolecular Chemistry, Molecular Structure, Bicyclic molecule, Hep G2 Cells, Metabolic stability, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Open source, chemistry, Cubane, Drug Design, Molecular Medicine, Bioisostere, 03 Chemical Sciences

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f34bc9127925044fdf21f6f9f792b7
    https://doi.org/10.1021/acs.jmedchem.0c00746

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  8. 8
    An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials

    المؤلفون: Davy Guan, Alexander Wade, Edwin G Tse, Alice Motion, Willem P. van Hoorn, Jonathan Cardoso-Silva, Adele M. Lehane, Giovanni Cincilla, Mario Öeren, Julia C. R. Lindblom, Mykola Galushka, Murray N. Robertson, Matthew H. Todd, James McCulloch, Slade Matthews, Mark G. Anderson, Benedict Irwin, Thomas M. Whitehead, Paul Willis, Laksh Aithani, Ho Leung Ng, Gareth Conduit, Vasileios A. Tatsis, Vito Spadavecchio, Raymond Lui, Kiaran Kirk, Irene Hallyburton

    المساهمون: Tse, Edwin G [0000-0002-9133-9274], Cincilla, Giovanni [0000-0002-5242-0707], Guan, Davy [0000-0001-6290-3166], Lehane, Adele M [0000-0002-0050-9101], Matthews, Slade [0000-0002-1652-543X], Motion, Alice [0000-0002-5859-7888], Ng, Ho Leung [0000-0002-6415-1938], Robertson, Murray N [0000-0001-9543-7667], Wade, Alexander D [0000-0003-1500-3733], Todd, Matthew H [0000-0001-7096-4751], Apollo - University of Cambridge Repository

    المصدر: Journal of medicinal chemistry. 64(22)

    مصطلحات موضوعية: RM, Plasmodium falciparum, Calcium-Transporting ATPases, Public domain, 01 natural sciences, Models, Biological, Competition (economics), 03 medical and health sciences, Antimalarials, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Enzyme Inhibitors, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Drug discovery, biology.organism_classification, Private sector, medicine.disease, Data science, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Identification (information), Molecular Medicine, Predictive modelling, Malaria

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226bb29c6cfb2827cc0b24dac6a0807c
    https://pubmed.ncbi.nlm.nih.gov/34748707

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  9. 9
    Preparation, biologicalcheminformatics-based assessment of N

    المؤلفون: Borvornwat, Toviwek, Oraphan, Phuangsawai, Adchatawut, Konsue, Supa, Hannongbua, Jennifer, Riley, Nicole, Mutter, Mark, Anderson, Lauren, Webster, Irene, Hallyburton, Kevin D, Read, M Paul, Gleeson

    المصدر: Bioorganicmedicinal chemistry. 46

    مصطلحات موضوعية: Antimalarials, Structure-Activity Relationship, Pyrimidines, Dose-Response Relationship, Drug, Molecular Structure, Parasitic Sensitivity Tests, Cheminformatics, Phosphotransferases, Plasmodium falciparum, Humans, Hep G2 Cells, Diamines, Enzyme Inhibitors

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9c0dbad3891c914370ca5711ed0cad7c
    https://pubmed.ncbi.nlm.nih.gov/34479064

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  10. 10
    The WeeCAIR Medicinal Garden Activity Pack

    المؤلفون: Ali Floyd, Irene Hallyburton, Ailsa Mackintosh

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b3790d9ee21a605b619b33046ad116d1
    https://doi.org/10.20933/100001191

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