المؤلفون: Moreth D; Institut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, D-97074, Würzburg, Germany., Stevens-Cullinane L; Biological Inorganic Chemistry Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Department of Chemistry, King's College London, Britannia House, 7 Trinity Street, London, SE1 1DB, UK., Rees TW; Biological Inorganic Chemistry Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Müller VVL; Institut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, D-97074, Würzburg, Germany., Pasquier A; High Throughput Screening Science and Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Song OR; High Throughput Screening Science and Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Warchal S; High Throughput Screening Science and Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Howell M; High Throughput Screening Science and Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK., Hess J; Biological Inorganic Chemistry Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Department of Chemistry, King's College London, Britannia House, 7 Trinity Street, London, SE1 1DB, UK., Schatzschneider U; Institut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, D-97074, Würzburg, Germany. ulrich.schatzschneider@uni-wuerzburg.de.

المصدر: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry [J Biol Inorg Chem] 2024 Sep; Vol. 29 (6), pp. 573-582. Date of Electronic Publication: 2024 Aug 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 9616326 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1327 (Electronic) Linking ISSN: 09498257 NLM ISO Abbreviation: J Biol Inorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/chemical synthesis , Biotin*/chemistry , Gold*/chemistry , Gold*/pharmacology , Iridium*/chemistry , Iridium*/pharmacology , Microbial Sensitivity Tests* , Platinum*/chemistry , Platinum*/pharmacology, Humans ; Coordination Complexes/chemistry ; Coordination Complexes/pharmacology ; Coordination Complexes/chemical synthesis ; Staphylococcus aureus/drug effects ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Guo L; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China. Electronic address: guolihua@qfnu.edu.cn., Li P; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China., Jing Z; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China., Gong Y; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China., Lai K; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China., Fu H; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China., Dong H; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China., Yang Z; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China., Liu Z; Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, PR China. Electronic address: liuzheqd@163.com.

المصدر: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Sep; Vol. 258, pp. 112631. Date of Electronic Publication: 2024 Jun 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Iridium*/chemistry , Iridium*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Ruthenium*/chemistry , Ruthenium*/pharmacology , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Mitochondria*/drug effects , Mitochondria*/metabolism , Cisplatin*/pharmacology , Drug Resistance, Neoplasm*/drug effects , Apoptosis*/drug effects, Humans ; A549 Cells ; HeLa Cells ; Reactive Oxygen Species/metabolism ; Membrane Potential, Mitochondrial/drug effects

المؤلفون: Lv A; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Li G; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Zhang P; College of Life Sciences, Qufu Normal University, Qufu 273165, Shandong, China., Tao R; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Li X; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Ren X; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Li P; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Liu X; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China. Electronic address: chemlxc@163.com., Yuan XA; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Liu Z; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China. Electronic address: liuzheqd@163.com.

المصدر: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Aug; Vol. 257, pp. 112612. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Iridium*/chemistry , Iridium*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Phenanthrolines*/chemistry , Phenanthrolines*/pharmacology , Imidazoles*/chemistry , Imidazoles*/pharmacology , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Apoptosis*/drug effects, Humans ; A549 Cells ; Reactive Oxygen Species/metabolism ; Phenanthrenes/chemistry ; Phenanthrenes/pharmacology ; Cell Proliferation/drug effects ; Lysosomes/metabolism ; Lysosomes/drug effects

المؤلفون: Ji C; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Dong R; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Zhang P; College of Life Sciences, Qufu Normal University, Qufu 273165, Shandong, China., Tao R; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Wang X; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Dai Q; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Liu X; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China. Electronic address: chemlxc@163.com., Yuan XA; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Zhang S; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China. Electronic address: zkz_mao@163.com., Yue M; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China., Liu Z; Key Laboratory of Life-Organic Analysis of Shandong Province, Institute of Anticancer Agents Development and Theranostic Application, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China. Electronic address: liuzheqd@163.com.

المصدر: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Aug; Vol. 257, pp. 112586. Date of Electronic Publication: 2024 May 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Ferrous Compounds*/chemistry , Ferrous Compounds*/pharmacology , Iridium*/chemistry , Iridium*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Metallocenes*/chemistry , Metallocenes*/pharmacology , Ruthenium*/chemistry , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Hydrazones*/chemistry , Hydrazones*/pharmacology , Hydrazones*/chemical synthesis , Apoptosis*/drug effects, Humans ; A549 Cells ; Reactive Oxygen Species/metabolism ; Cell Proliferation/drug effects

المؤلفون: Chen SQ; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, PR China., Lu XY; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, PR China., Zhu LY; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, PR China., Zhu H; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, PR China., Li RT; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, PR China. Electronic address: rongtaolikm@163.com., Ye RR; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, PR China. Electronic address: yerr@mail2.sysu.du.cn.

المصدر: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Aug; Vol. 257, pp. 112596. Date of Electronic Publication: 2024 May 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Iridium*/chemistry , Iridium*/pharmacology , Ibuprofen*/pharmacology , Ibuprofen*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Apoptosis*/drug effects, Humans ; Membrane Potential, Mitochondrial/drug effects ; Reactive Oxygen Species/metabolism ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Design

المؤلفون: Jin W; Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China.; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China.; Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Xie X; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China.; Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Shen S; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China.; Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Zhou X; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China.; Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Wang S; Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Zhang L; Translational Medicine Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Su X; Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People's Republic of China.

المصدر: Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2024 Jul; Vol. 112 (7), pp. 988-1003. Date of Electronic Publication: 2024 Feb 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101234237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4965 (Electronic) Linking ISSN: 15493296 NLM ISO Abbreviation: J Biomed Mater Res A Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatitis*/drug therapy , Povidone*/chemistry , Povidone*/pharmacology , Antioxidants*/pharmacology , Antioxidants*/chemistry , Iridium*/chemistry , Iridium*/pharmacology , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/chemistry , Anti-Inflammatory Agents*/therapeutic use , Reactive Oxygen Species*/metabolism, Animals ; Mice ; Metal Nanoparticles/chemistry ; Metal Nanoparticles/therapeutic use ; Male ; Oxidative Stress/drug effects ; RAW 264.7 Cells ; Acute Disease

المؤلفون: Tian S; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China., Nie Q; Department of Microbiology and Immunology, Guangdong Pharmaceutical University, Guangzhou 510006, China., Chen H; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China., Liang L; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China., Hu H; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China., Tang S; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China., Yang J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China., Liu Y; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address: lyjche@gdpu.edu.cn., Yin H; Department of Microbiology and Immunology, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address: huiyin0103@gdpu.edu.cn.

المصدر: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Jul; Vol. 256, pp. 112549. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Liposomes* , Iridium*/chemistry , Iridium*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Apoptosis*/drug effects, Humans ; Cell Proliferation/drug effects ; Cell Line, Tumor ; Membrane Potential, Mitochondrial/drug effects

المؤلفون: Hu H; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China., Chen J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China., Zhang F; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China., Sheng Z; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China., Yang Y; Department of Pharmacy, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou 510317, PR China., Xie Y; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China., Zhou L; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China., Liu Y; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Sep 26; Vol. 67 (18), pp. 16195-16208. Date of Electronic Publication: 2024 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Iridium*/chemistry , Iridium*/pharmacology , Liposomes* , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Coordination Complexes*/chemistry , Coordination Complexes*/pharmacology , Coordination Complexes*/chemical synthesis , Coordination Complexes*/therapeutic use , Apoptosis*/drug effects, Animals ; Mice ; Cell Line, Tumor ; Humans ; Mice, Inbred C57BL ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Melanoma, Experimental/drug therapy ; Melanoma, Experimental/pathology ; Melanoma, Experimental/metabolism ; Membrane Potential, Mitochondrial/drug effects

المؤلفون: Li Y; Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, P. R. China., Liu B; Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, P. R. China.; Centre for Translational Medicine Research & Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China., Zheng Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, IGCME, Sun Yat-Sen University, Guangzhou 510275, P. R. China., Hu M; Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, P. R. China.; Centre for Translational Medicine Research & Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China., Liu LY; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, IGCME, Sun Yat-Sen University, Guangzhou 510275, P. R. China., Li CR; Centre for Translational Medicine Research & Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China., Zhang W; Centre for Translational Medicine Research & Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China., Lai YX; Centre for Translational Medicine Research & Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China., Mao ZW; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, IGCME, Sun Yat-Sen University, Guangzhou 510275, P. R. China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Sep 26; Vol. 67 (18), pp. 16235-16247. Date of Electronic Publication: 2024 Sep 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis*/drug effects , Iridium*/chemistry , Iridium*/pharmacology , Nucleotidyltransferases*/metabolism , Membrane Proteins*/metabolism, Humans ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Photochemotherapy ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/therapeutic use ; Coordination Complexes/pharmacology ; Coordination Complexes/chemistry ; Animals ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Neoplasms/pathology ; Cell Line, Tumor ; Mice ; DNA, Mitochondrial/metabolism ; Reactive Oxygen Species/metabolism

المؤلفون: Jones C; School of Medicine and Population Health, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, U.K.; Department of Chemistry, University of Sheffield, Sheffield S3 7HF, U.K., Martinez-Alonso M; School of Medicine and Population Health, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, U.K.; Department of Chemistry, University of Sheffield, Sheffield S3 7HF, U.K., Gagg H; School of Medicine and Population Health, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, U.K., Kirby L; Department of Chemistry, University of Sheffield, Sheffield S3 7HF, U.K., Weinstein JA; Department of Chemistry, University of Sheffield, Sheffield S3 7HF, U.K., Bryant HE; School of Medicine and Population Health, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Sep 26; Vol. 67 (18), pp. 16157-16164. Date of Electronic Publication: 2024 Sep 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Photosensitizing Agents*/pharmacology , Photosensitizing Agents*/chemistry , Photosensitizing Agents*/chemical synthesis , Iridium*/chemistry , Iridium*/pharmacology , Light* , Photochemotherapy* , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Coordination Complexes*/radiation effects, Humans ; Cell Line, Tumor ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Reactive Oxygen Species/metabolism