نتائج البحث - "Irina I. Mohorianu"

المؤلفون: Gribben C; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Open Targets, Wellcome Genome Campus, Hinxton, UK., Galanakis V; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Open Targets, Wellcome Genome Campus, Hinxton, UK.; Liver Unit, Department of Medicine, Cambridge NIHR Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Calderwood A; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Williams EC; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Chazarra-Gil R; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Larraz M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Frau C; Berlin Institute of Health Centre for Regenerative Therapies, Berlin, Germany., Puengel T; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany., Guillot A; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany., Rouhani FJ; Francis Crick Institute, London, UK., Mahbubani K; Department of Surgery, University of Cambridge, Cambridge, UK., Godfrey E; Department of Radiology, Addenbrooke's Hospital, Cambridge, UK., Davies SE; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Athanasiadis E; Greek Genome Centre, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.; Medical Image and Signal Processing Laboratory, Department of Biomedical Engineering, University of West Attica, Athens, Greece., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge, UK., Tacke F; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany., Allison M; Open Targets, Wellcome Genome Campus, Hinxton, UK. michael.allison6@nhs.net.; Liver Unit, Department of Medicine, Cambridge NIHR Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. michael.allison6@nhs.net., Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. iim22@cam.ac.uk., Vallier L; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. ludovic.vallier@bih-charite.de.; Open Targets, Wellcome Genome Campus, Hinxton, UK. ludovic.vallier@bih-charite.de.; Berlin Institute of Health Centre for Regenerative Therapies, Berlin, Germany. ludovic.vallier@bih-charite.de.; Max Planck Institute for Molecular Genetics, Berlin, Germany. ludovic.vallier@bih-charite.de.

المصدر: Nature [Nature] 2024 Jun; Vol. 630 (8015), pp. 166-173. Date of Electronic Publication: 2024 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cell Transdifferentiation* , Hepatocytes*/metabolism , Hepatocytes*/cytology , Hepatocytes*/pathology , Liver*/pathology , Liver*/metabolism , Liver*/cytology , Liver Diseases*/pathology , Liver Diseases*/metabolism, Humans ; Biliary Tract/cytology ; Biliary Tract/metabolism ; Biliary Tract/pathology ; Biopsy ; Cell Plasticity ; Chronic Disease ; Disease Progression ; Epithelial Cells/metabolism ; Epithelial Cells/cytology ; Epithelial Cells/pathology ; Insulin/metabolism ; Liver Regeneration ; Organoids/metabolism ; Organoids/pathology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA-Seq ; Signal Transduction ; Single-Cell Analysis ; TOR Serine-Threonine Kinases/metabolism

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Proinflammatory cytokines driving cardiotoxicity in COVID-19.

المؤلفون: Colzani M; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, CB2 0AW Cambridge, UK.; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK., Bargehr J; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, CB2 0AW Cambridge, UK.; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK., Mescia F; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Puddicombe Way, CB2 0AW Cambridge, UK., Williams EC; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, CB2 0AW Cambridge, UK., Knight-Schrijver V; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, CB2 0AW Cambridge, UK.; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK., Lee J; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, CB2 0AW Cambridge, UK.; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK., Summers C; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK.; Wolfson Lung Injury Unit, Heart and Lung Research Institute, Cambridge Biomedical Campus, Papworth Road, CB2 0BB Cambridge, UK., Mohorianu I; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, CB2 0AW Cambridge, UK., Smith KGC; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Puddicombe Way, CB2 0AW Cambridge, UK., Lyons PA; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Puddicombe Way, CB2 0AW Cambridge, UK., Sinha S; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Puddicombe Way, CB2 0AW Cambridge, UK.; Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Addenbrooke's Hospital, Hills Rd, CB2 0SP Cambridge, UK.

المصدر: Cardiovascular research [Cardiovasc Res] 2024 Mar 13; Vol. 120 (2), pp. 174-187.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*, Humans ; Cytokines ; Cardiotoxicity ; Interleukin-6 ; Tumor Necrosis Factor-alpha

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Human surface ectoderm and amniotic ectoderm are sequentially specified according to cellular density.

المؤلفون: Nakanoh S; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.; Epigenetics & Signalling Programmes, Babraham Institute, Cambridge CB22 3AT, UK., Sham K; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Ghimire S; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Rayon T; Epigenetics & Signalling Programmes, Babraham Institute, Cambridge CB22 3AT, UK., Vallier L; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.; Berlin Institute of Health Centre for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Berlin 13353, Germany.; Max Planck Institute for Molecular Genetics, Berlin 14195, Germany.

المصدر: Science advances [Sci Adv] 2024 Mar; Vol. 10 (9), pp. eadh7748. Date of Electronic Publication: 2024 Mar 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Ectoderm*/metabolism , Pluripotent Stem Cells*, Humans ; Cell Differentiation/genetics ; Mesoderm

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Prevalence and significance of DDX41 gene variants in the general population.

المؤلفون: Cheloor Kovilakam S; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Gu M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Dunn WG; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom., Marando L; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom., Barcena C; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Department of Biochemistry and Molecular Biology, Universidad de Oviedo, Oviedo, Spain., Nik-Zainal S; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, United Kingdom., Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Kar SP; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, United Kingdom.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Section of Translational Epidemiology, Division of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Fabre MA; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals Research and Development, AstraZeneca, Cambridge, United Kingdom., Quiros PM; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain., Vassiliou GS; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom.

المصدر: Blood [Blood] 2023 Oct 05; Vol. 142 (14), pp. 1185-1192.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Myelodysplastic Syndromes*/epidemiology , Myelodysplastic Syndromes*/genetics , Leukemia, Myeloid, Acute*/genetics , GATA2 Deficiency*, Humans ; Prevalence ; DEAD-box RNA Helicases/genetics ; DNA

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Author Correction: Multiparameter prediction of myeloid neoplasia risk.

المؤلفون: Gu M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Kovilakam SC; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Dunn WG; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Marando L; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Barcena C; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Department of Biochemistry and Molecular Biology, Universidad de Oviedo, Oviedo, Spain., Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Smith A; Epidemiology and Cancer Statistics Group, University of York, York, UK., Kar SP; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Section of Translational Epidemiology, Division of Population Health Sciences, Bristol, Medical School, University of Bristol, Bristol, UK.; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Fabre MA; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Gerstung M; Division of Artificial Intelligence in Oncology, DKFZ, Heidelberg, Germany., Cargo CA; Haematological Malignancy Diagnostic Service, St James's Hospital, Leeds, UK.; Department of Haematology, Leeds Teaching Hospitals, Leeds, UK., Malcovati L; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Department of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Quiros PM; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. pmquiros@ispasturias.es.; Department of Haematology, University of Cambridge, Cambridge, UK. pmquiros@ispasturias.es.; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain. pmquiros@ispasturias.es., Vassiliou GS; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. gsv20@cam.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. gsv20@cam.ac.uk.; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge, UK. gsv20@cam.ac.uk.

المصدر: Nature genetics [Nat Genet] 2023 Oct; Vol. 55 (10), pp. 1777.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: PubMed not MEDLINE; MEDLINE

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دورية أكاديمية

Multiparameter prediction of myeloid neoplasia risk.

المؤلفون: Gu M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Kovilakam SC; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Dunn WG; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Marando L; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Barcena C; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Department of Biochemistry and Molecular Biology, Universidad de Oviedo, Oviedo, Spain., Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Smith A; Epidemiology and Cancer Statistics Group, University of York, York, UK., Kar SP; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Section of Translational Epidemiology, Division of Population Health Sciences, Bristol, Medical School, University of Bristol, Bristol, UK.; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Fabre MA; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Gerstung M; Division of Artificial Intelligence in Oncology, DKFZ, Heidelberg, Germany., Cargo CA; Haematological Malignancy Diagnostic Service, St James's Hospital, Leeds, UK.; Department of Haematology, Leeds Teaching Hospitals, Leeds, UK., Malcovati L; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Department of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Quiros PM; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. pmquiros@ispasturias.es.; Department of Haematology, University of Cambridge, Cambridge, UK. pmquiros@ispasturias.es.; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain. pmquiros@ispasturias.es., Vassiliou GS; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. gsv20@cam.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. gsv20@cam.ac.uk.; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge, UK. gsv20@cam.ac.uk.

المصدر: Nature genetics [Nat Genet] 2023 Sep; Vol. 55 (9), pp. 1523-1530. Date of Electronic Publication: 2023 Aug 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Clonal Hematopoiesis* , Neoplasms*, Humans ; Family ; Mutation ; Software

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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.

المؤلفون: Haston S; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK. Electronic address: scott.haston.13@ucl.ac.uk., Gonzalez-Gualda E; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Morsli S; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Ge J; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Reen V; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Calderwood A; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Moutsopoulos I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Panousopoulos L; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Deletic P; Division of Medicine, University College London, London, UK., Carreno G; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Guiho R; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Manshaei S; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Gonzalez-Meljem JM; Tecnologico de Monterrey, School of Engineering and Sciences, Mexico City, Mexico., Lim HY; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Simpson DJ; MRC Human Generics Unit, University of Edinburgh, Edinburgh, UK., Birch J; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Pallikonda HA; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Chandra T; MRC Human Generics Unit, University of Edinburgh, Edinburgh, UK., Macias D; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK., Doherty GJ; Cambridge University Hospitals NHS Foundation Trust, Department of Oncology, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK., Rassl DM; Royal Papworth Hospital NHS Foundation Trust. Cambridge Biomedical Campus, Cambridge CB2 0AY, UK., Rintoul RC; Royal Papworth Hospital NHS Foundation Trust. Cambridge Biomedical Campus, Cambridge CB2 0AY, UK; Department of Oncology, University of Cambridge, Cambridge, UK; CRUK Cambridge Centre Thoracic Cancer Programme, Cambridge, UK., Signore M; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK., Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK., Akbar AN; Division of Medicine, University College London, London, UK., Gil J; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Muñoz-Espín D; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK; CRUK Cambridge Centre Thoracic Cancer Programme, Cambridge, UK. Electronic address: dm742@cam.ac.uk., Martinez-Barbera JP; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK. Electronic address: j.martinez-barbera@ucl.ac.uk.

المصدر: Cancer cell [Cancer Cell] 2023 Jul 10; Vol. 41 (7), pp. 1242-1260.e6. Date of Electronic Publication: 2023 Jun 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cellular Senescence*/genetics , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism, Aged ; Animals ; Humans ; Mice ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Endothelial Cells ; Macrophages/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Tumor Microenvironment

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دورية أكاديمية

Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma.

المؤلفون: Hoppe MM; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Jaynes P; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Shuangyi F; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Peng Y; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Sridhar S; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Hoang PM; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Liu CX; Department of Haematology-Oncology, National University Health System, Singapore, Singapore., De Mel S; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Poon L; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chan EHL; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lee J; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ong CK; Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, Singapore., Tang T; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Lim ST; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Nagarajan C; Department of Haematology, Singapore General Hospital, Singapore, Singapore., Grigoropoulos NF; Department of Haematology, Singapore General Hospital, Singapore, Singapore., Tan SY; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Hue SS; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chang ST; Department of Pathology, Chi-Mei Medical Center, Tainan City, Taiwan., Chuang SS; Department of Pathology, Chi-Mei Medical Center, Tainan City, Taiwan., Li S; Department of Hematopathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Khoury JD; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska., Choi H; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Harris C; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Bottos A; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Gay LJ; Wellcome MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom., Runge HFP; Wellcome MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom., Moutsopoulos I; Wellcome MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom., Mohorianu I; Wellcome MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom., Hodson DJ; Wellcome MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom., Farinha P; BC Cancer Research Centre, Vancouver, Canada., Mottok A; BC Cancer Research Centre, Vancouver, Canada., Scott DW; BC Cancer Research Centre, Vancouver, Canada., Pitt JJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Chen J; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Kumar G; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kannan K; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chng WJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chee YL; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ng SB; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tripodo C; Tumor Immunology Unit, University of Palermo, Palermo, Italy.; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Jeyasekharan AD; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

المصدر: Cancer discovery [Cancer Discov] 2023 May 04; Vol. 13 (5), pp. 1144-1163.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Phosphatidylinositol 3-Kinases*/genetics , Lymphoma, Large B-Cell, Diffuse*/pathology, Humans ; Proto-Oncogene Proteins c-bcl-6/genetics ; Prognosis ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Oncogenes

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