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المؤلفون: James R. Kiefer, Joseph W. Leone, Alfredo G. Tomasselli, Robin A. Weinberg, Akshay Patny, H. David Fischer, Cynthia D. Sommers, Jennifer A. Gormley, Timothy E. Benson, Horng-Chih Huang, E.J. Jacobsen, Jacqueline E. Day, Thomas L. Emmons, Jill Chrencik, Iris K. Leung, Jeffrey L. Hirsch, Tenbrink Ruth E, Jennifer M. Williams, Brian Korniski, Troii Hall
المصدر: Journal of Molecular Biology. 400:413-433
مصطلحات موضوعية: Models, Molecular, Nitrile, Pyridones, Stereochemistry, Calorimetry, Isozyme, chemistry.chemical_compound, Protein structure, Piperidines, Structural Biology, Humans, Transferase, Pyrroles, Enzyme Inhibitors, Molecular Biology, TYK2 Kinase, Binding Sites, Kinase, Chemistry, Janus Kinase 3, Isothermal titration calorimetry, Protein Structure, Tertiary, Kinetics, Pyrimidines, Tyrosine kinase 2, Benzimidazoles, Janus kinase, Protein Binding
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2
المؤلفون: Haile Tecle, Patrick I. McConnell, Iris K. Leung, Cindy Spessard, W. Thomas Mueller, Cathlin Marie Flamme, Alexander Pavlovsky, Chunhong Yan, Stephen Douglas Barrett, Craig Banotai, Judith Sebolt-Leopold, Joseph S. Warmus, Charles Omer, Jeffrey F. Ohren, Erli Zhang, Charles A. Hasemann, Amy M. Delaney, Peter Kuffa, Christopher Whitehead, Huifen Chen, David T. Dudley, Michael Kaufman
المصدر: Nature structuralmolecular biology. 11(12)
مصطلحات موضوعية: Models, Molecular, Binding Sites, biology, MAP kinase kinase kinase, Molecular Structure, Cyclin-dependent kinase 4, Cyclin-dependent kinase 2, MAP Kinase Kinase 2, MAP Kinase Kinase 1, Mitogen-activated protein kinase kinase, MAP2K7, Cell biology, Biochemistry, Structural Biology, Structural Homology, Protein, biology.protein, Humans, ASK1, Cyclin-dependent kinase 9, c-Raf, Enzyme Inhibitors, Protein Structure, Quaternary, Molecular Biology, Dimerization, Conserved Sequence
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3
المؤلفون: Jeffrey F. Ohren, Peter Kuffa, Cindy Spessard, Iris K. Leung, Judith S. Sebolt-Leopold, W. Thomas Mueller, Alexander Pavlovsky, Erli Zhang, David T. Dudley, Charles Omer, Joseph S. Warmus, Michael Kaufman, Cathlin Marie Flamme, Christopher Whitehead, Haile Tecle, Stephen Douglas Barrett, Huifen Chen, Patrick I. McConnell, Charles A. Hasemann, Craig Banotai, Chunhong Yan, Amy M. Delaney
المصدر: Nature Structural & Molecular Biology. 12:278-278
مصطلحات موضوعية: MAP kinase kinase kinase, Chemistry, MAPKAPK2, MAPK7, Mitogen-activated protein kinase kinase, Molecular biology, Cell biology, Biochemistry, TANK-binding kinase 1, Structural Biology, Cyclin-dependent kinase 9, c-Raf, Molecular Biology, MAPK14