المؤلفون: Manuel Schweighauser, Alexey G. Murzin, Jennifer Macdonald, Isabelle Lavenir, R. Anthony Crowther, Sjors H.W. Scheres, Michel Goedert

المصدر: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-11 (2023)

مصطلحات موضوعية: P301S tau, Frontotemporal dementia and parkinsonism linked to chromosome 17, Transgenic mice, Electron cryo-microscopy, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/43edd87f5ecc46a6b3d9100ebbe7d73f

المؤلفون: Jennifer A. Macdonald, John L. Chen, Masami Masuda-Suzukake, Manuel Schweighauser, Zane Jaunmuktane, Thomas Warner, Janice L. Holton, Annabelle Grossman, Richard Berks, Isabelle Lavenir, Michel Goedert

المصدر: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: α-Synuclein, Multiple system atrophy, Seeded assembly, Neurodegeneration, Microglia, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/bb04ab8adf9d41ed8dc3cbb1e5c3ee4c

المؤلفون: Isabelle Lavenir, Daniela Passarella, Masami Masuda-Suzukake, Annabelle Curry, Janice L. Holton, Bernardino Ghetti, Michel Goedert

المصدر: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: α-Synuclein, Multiple system atrophy, Parkinson’s disease, Seeding, Silver staining, Transgenic, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0804-5; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/f2e2357037754171bea60e9a5183766a

المؤلفون: Jennifer A. Macdonald, Iraad F. Bronner, Lesley Drynan, Juan Fan, Annabelle Curry, Graham Fraser, Isabelle Lavenir, Michel Goedert

المصدر: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Tau assembly, Neurodegeneration, Tauopathy, β-Sheet structure, Tau filaments, Sarkosyl-insoluble tau, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0695-5; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/b5e78336638247b6b7a93dfe965c6c2a

المؤلفون: Yang Yang, Wenjuan Zhang, Alexey G. Murzin, Manuel Schweighauser, Melissa Huang, Sofia Lövestam, Sew Y. Peak-Chew, Takashi Saito, Takaomi C. Saido, Jennifer Macdonald, Isabelle Lavenir, Bernardino Ghetti, Caroline Graff, Amit Kumar, Agneta Nordberg, Michel Goedert, Sjors H. W. Scheres

المساهمون: Scheres, Sjors HW [0000-0002-0462-6540], Apollo - University of Cambridge Repository

المصدر: Acta neuropathologica.

مصطلحات موضوعية: Amyloid beta-Peptides, Cryoelectron Microscopy, Brain, Mice, Transgenic, Arctic mutation, Electron cryo-microscopy, Pathology and Forensic Medicine, Mice, Amyloid beta-Protein Precursor, Cellular and Molecular Neuroscience, Alzheimer Disease, Mutation, Mouse App NL−G−F knock-in line, Humans, Animals, Neurology (clinical), Amyloid-beta, Tau, Alzheimer’s disease

وصف الملف: text/xml; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084ff36d086a4dcbffb5d0983f871c89
https://pubmed.ncbi.nlm.nih.gov/36611124

المؤلفون: Masami Masuda-Suzukake, Michel Goedert, Daniela Passarella, Isabelle Lavenir, Dennis W. Dickson, Sophie A. Morgan, X. Bernardino Ghetti, Michael DeTure, Juan Fan

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: alpha-synuclein (α-synuclein), 0301 basic medicine, Genetically modified mouse, Synucleinopathies, Mutant, multiple system atrophy, Mice, Transgenic, Fibril, seeded aggregation, Biochemistry, oligomer, Transgenic, Mice, 03 medical and health sciences, Atrophy, Neurobiology, mental disorders, medicine, Animals, Humans, Molecular Biology, brain disease, Lewy body, Parkinson disease, fibril, neurodegeneration, synucleinopathy, Brain, HEK293 Cells, Homozygote, alpha-Synuclein, 030102 biochemistry & molecular biology, Chemistry, Neurodegeneration, Cell Biology, Transfection, medicine.disease, Molecular biology, nervous system diseases, 030104 developmental biology, nervous system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22c68821794f5bb03ed47ebcad2f54e
https://doi.org/10.1074/jbc.ra119.012179

المؤلفون: Janice L. Holton, Zane Jaunmuktane, John L Chen, Thomas T. Warner, Masami Masuda-Suzukake, Michel Goedert, Annabelle Grossman, Richard Berks, Manuel Schweighauser, Isabelle Lavenir, Jennifer A. Macdonald

المساهمون: Apollo - University of Cambridge Repository

المصدر: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Acta Neuropathologica Communications

مصطلحات موضوعية: Male, medicine.medical_specialty, Pathology, Neurology, medicine.medical_treatment, animal diseases, Intraperitoneal injection, Mutant, Central nervous system, Seeded assembly, Pathology and Forensic Medicine, Animals, Genetically Modified, Mice, Neurologic Mutants, Cellular and Molecular Neuroscience, Atrophy, mental disorders, medicine, Animals, Humans, Paralysis, Neurodegeneration, RC346-429, Aged, Motor Neurons, Neurons, α-Synuclein, Movement Disorders, Microglia, Chemistry, Research, Neurodegenerative Diseases, Multiple system atrophy, medicine.disease, Immunohistochemistry, Hindlimb, nervous system diseases, medicine.anatomical_structure, nervous system, Mutation, alpha-Synuclein, Nasal administration, Neurology (clinical), Neurology. Diseases of the nervous system

وصف الملف: application/pdf; text/xml; application/zip

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86869e0e4249259b4e469687b4f3482
https://www.repository.cam.ac.uk/handle/1810/331029

المؤلفون: Alexey G. Murzin, Wenjuan Zhang, Melissa Huang, Kathy L. Newell, Isabelle Lavenir, Ellen Gelpi, Bernardino Ghetti, Sofia Lövestam, Michel Goedert, Holly J. Garringer, Sew Y. Peak-Chew, Abhay Kotecha, Benjamin Falcon, Yang Yang, Jennifer A. Macdonald, Gabor G. Kovacs, Sjors H.W. Scheres, Manuel Schweighauser, Diana Arseni, Ruben Vidal

المصدر: Science

مصطلحات موضوعية: Male, Models, Molecular, Protein Folding, Amyloid β, Protein Conformation, Cryo-electron microscopy, macromolecular substances, Type (model theory), Article, Protein filament, Mice, Protein Domains, Alzheimer Disease, medicine, Animals, Humans, Amino Acid Sequence, Gene Knock-In Techniques, Beta (finance), Aged, Aged, 80 and over, Brain Chemistry, Multidisciplinary, Amyloid beta-Peptides, Chemistry, Cryoelectron Microscopy, Human brain, Middle Aged, Peptide Fragments, medicine.anatomical_structure, Models, Animal, Biophysics, Female, Protein Conformation, beta-Strand

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a48e57feff85f04c66cbb2d57cbd196
https://doi.org/10.1101/2021.10.19.464936

المؤلفون: Melissa Huang, Jennifer Macdonald, Isabelle Lavenir, Renren Chen, Molly Craxton, Elizabeth Slavik-Smith, Stephen W. Davies, Michel Goedert

المصدر: eneuro. 9:ENEURO.0247-22.2022

مصطلحات موضوعية: General Neuroscience, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dd137a2b59a43d518afcfa5639a64c34
https://doi.org/10.1523/eneuro.0247-22.2022

المؤلفون: Annabelle Curry, Michel Goedert, Bernardino Ghetti, Janice L. Holton, Masami Masuda-Suzukake, Isabelle Lavenir, Daniela Passarella

المساهمون: Apollo - University of Cambridge Repository

المصدر: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Acta Neuropathologica Communications

مصطلحات موضوعية: Genetically modified mouse, Parkinson's disease, Transgene, animal diseases, Seeding, Mice, Transgenic, Silver staining, Transgenic, lcsh:RC346-429, Pathology and Forensic Medicine, Stereotaxic Techniques, Silver stain, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Atrophy, mental disorders, medicine, Animals, Humans, lcsh:Neurology. Diseases of the nervous system, 030304 developmental biology, Brain Chemistry, Neurons, Synucleinopathies, α-Synuclein, 0303 health sciences, Dementia with Lewy bodies, Chemistry, Research, Neurodegeneration, Brain, Parkinson Disease, Multiple system atrophy, medicine.disease, Molecular biology, nervous system diseases, nervous system, alpha-Synuclein, Parkinson’s disease, Neurology (clinical), 030217 neurology & neurosurgery

وصف الملف: text/xml; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1eefcec6c283f1641c7fafb796bf6e
http://link.springer.com/article/10.1186/s40478-019-0804-5