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المؤلفون: McKay-Corkum GB; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Collins VJ; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Yeung C; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Ito T; Urologic Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Issaq SH; Urologic Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Holland D; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Bethesda, Maryland., Vulikh K; Molecular Histopathology Lab, Frederick National Laboratory for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Zhang Y; National Clinical Target Validation Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Lee U; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Lei H; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Mendoza A; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Shern JF; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Yohe ME; Laboratory of Cell and Developmental Signaling, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Yamamoto K; Radiation Biology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Wilson K; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Bethesda, Maryland., Ji J; National Clinical Target Validation Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Karim BO; Molecular Histopathology Lab, Frederick National Laboratory for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Thomas CJ; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health (NIH), Bethesda, Maryland., Krishna MC; Radiation Biology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Neckers LM; Urologic Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland., Heske CM; Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Nov 01; Vol. 29 (21), pp. 4479-4491.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: NAD*/metabolism , Rhabdomyosarcoma*/drug therapy, Humans ; Cytokines/metabolism ; Nicotinamide Phosphoribosyltransferase/metabolism ; Pyrazoles ; Necrosis ; Cell Line, Tumor

المؤلفون: Gibson AE; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Yeung C; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Issaq SH; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Collins VJ; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Gouzoulis M; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Zhang Y; National Clinical Target Validation Laboratory, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Ji J; National Clinical Target Validation Laboratory, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Mendoza A; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Heske CM; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Christine.heske@nih.gov.

المصدر: Oncogenesis [Oncogenesis] 2020 Sep 10; Vol. 9 (9), pp. 80. Date of Electronic Publication: 2020 Sep 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101580004 Publication Model: Electronic Cited Medium: Print ISSN: 2157-9024 (Print) Linking ISSN: 21579024 NLM ISO Abbreviation: Oncogenesis Subsets: PubMed not MEDLINE

المؤلفون: Issaq SH; Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland. issaqsh@mail.nih.gov., Mendoza A; Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland., Kidner R; Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland., Rosales TI; Children's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas., Duveau DY; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., Heske CM; Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland., Rohde JM; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., Boxer MB; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., Thomas CJ; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., DeBerardinis RJ; Children's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas., Helman LJ; Pediatric Oncology Branch, NCI, NIH, Bethesda, Maryland.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2020 Jul; Vol. 19 (7), pp. 1520-1529. Date of Electronic Publication: 2020 May 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation* , Gene Expression Regulation, Neoplastic*, Bone Neoplasms/*pathology , Oncogene Proteins, Fusion/*metabolism , Phosphoglycerate Dehydrogenase/*metabolism , Proto-Oncogene Protein c-fli-1/*metabolism , RNA-Binding Protein EWS/*metabolism , Sarcoma, Ewing/*pathology , Serine/*metabolism, Animals ; Apoptosis ; Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Female ; Humans ; Mice ; Mice, SCID ; Oncogene Proteins, Fusion/genetics ; Proto-Oncogene Protein c-fli-1/genetics ; RNA-Binding Protein EWS/genetics ; Sarcoma, Ewing/genetics ; Sarcoma, Ewing/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

المؤلفون: Ren L; 1Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Ruiz-Rodado V; 2Metabolomics Section, NeuroOncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Dowdy T; 2Metabolomics Section, NeuroOncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Huang S; 1Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Issaq SH; 3Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Beck J; 4Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Wang H; 1Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Tran Hoang C; 1Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Lita A; 2Metabolomics Section, NeuroOncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., Larion M; 2Metabolomics Section, NeuroOncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA., LeBlanc AK; 1Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.

المصدر: Cancer & metabolism [Cancer Metab] 2020 Mar 05; Vol. 8, pp. 4. Date of Electronic Publication: 2020 Mar 05 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101607582 Publication Model: eCollection Cited Medium: Print ISSN: 2049-3002 (Print) Linking ISSN: 20493002 NLM ISO Abbreviation: Cancer Metab Subsets: PubMed not MEDLINE

المؤلفون: Issaq SH; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health., Heske CM; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

المصدر: Current opinion in pediatrics [Curr Opin Pediatr] 2020 Feb; Vol. 32 (1), pp. 26-34.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Review

بيانات الدورية: Publisher: Lippincott Williams and Wilkins Country of Publication: United States NLM ID: 9000850 Publication Model: Print Cited Medium: Internet ISSN: 1531-698X (Electronic) Linking ISSN: 10408703 NLM ISO Abbreviation: Curr Opin Pediatr Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Targeted Therapy*/methods , Molecular Targeted Therapy*/trends, Antineoplastic Agents/*metabolism , Metabolic Networks and Pathways/*drug effects , Neoplasms/*drug therapy , Neoplasms/*metabolism, Amino Acids/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Child ; Folic Acid/metabolism ; Glycolysis/drug effects ; Glycolysis/physiology ; Humans ; Metabolic Networks and Pathways/physiology ; NAD/metabolism ; Oxidative Phosphorylation/drug effects ; Polyamines/metabolism

المؤلفون: Yeung C; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Gibson AE; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Issaq SH; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Oshima N; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Baumgart JT; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Edessa LD; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Rai G; Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland., Urban DJ; Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland., Johnson MS; Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama., Benavides GA; Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama., Squadrito GL; Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama., Yohe ME; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Lei H; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Eldridge S; Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Hamre J 3rd; Laboratory of Investigative Toxicology, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Dowdy T; Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Ruiz-Rodado V; Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Lita A; Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Mendoza A; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Shern JF; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Larion M; Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Helman LJ; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Stott GM; Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland., Krishna MC; Radiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Hall MD; Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland., Darley-Usmar V; Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama., Neckers LM; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Heske CM; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Christine.heske@nih.gov.

المصدر: Cancer research [Cancer Res] 2019 Oct 01; Vol. 79 (19), pp. 5060-5073. Date of Electronic Publication: 2019 Aug 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Glycolysis/*drug effects , L-Lactate Dehydrogenase/*antagonists & inhibitors , Sarcoma, Ewing/*pathology, Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Mice ; Mice, SCID ; Sarcoma, Ewing/metabolism ; Xenograft Model Antitumor Assays

المؤلفون: Issaq SH; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. issaqsh@mail.nih.gov., Mendoza A; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Fox SD; Protein Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Helman LJ; Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Departments of Pediatrics and Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.

المصدر: Oncogenesis [Oncogenesis] 2019 Feb 26; Vol. 8 (3), pp. 20. Date of Electronic Publication: 2019 Feb 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101580004 Publication Model: Electronic Cited Medium: Print ISSN: 2157-9024 (Print) Linking ISSN: 21579024 NLM ISO Abbreviation: Oncogenesis Subsets: PubMed not MEDLINE

المؤلفون: Issaq SH; Molecular Pharmacology Branch; Leidos Biomedical Research, Inc.; Frederick National Laboratory for Cancer Research; Frederick, MD USA., Teicher BA; Division of Cancer Treatment and Diagnosis; National Cancer Institute; Rockville, MD USA., Monks A; Molecular Pharmacology Branch; Leidos Biomedical Research, Inc.; Frederick National Laboratory for Cancer Research; Frederick, MD USA.

المصدر: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2014; Vol. 13 (7), pp. 1152-61. Date of Electronic Publication: 2014 Feb 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-4005 (Electronic) Linking ISSN: 15514005 NLM ISO Abbreviation: Cell Cycle Subsets: MEDLINE

مواضيع طبية MeSH: Bone Neoplasms/*metabolism , Energy Metabolism/*drug effects , Osteosarcoma/*metabolism, Bone Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Respiration/drug effects ; Deoxyglucose/pharmacology ; Electron Transport Complex I/antagonists & inhibitors ; Glycolysis/drug effects ; Humans ; Hypoglycemic Agents/pharmacology ; Metformin/pharmacology ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondrial Proton-Translocating ATPases/antagonists & inhibitors ; Oligomycins/pharmacology ; Osteosarcoma/pathology

المؤلفون: Issaq SH; Department of Pharmacology and Cancer Biology, Duke University Medical Center, DUMC-3813, Durham, NC 27710, USA., Lim KH, Counter CM

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2010 Feb; Vol. 8 (2), pp. 223-31. Date of Electronic Publication: 2010 Feb 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Cell Transformation, Neoplastic/*metabolism , Neoplasms/*metabolism , Oncogenes/*genetics , Vesicular Transport Proteins/*metabolism , ras Proteins/*metabolism, ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/metabolism ; Cell Line ; Cell Transformation, Neoplastic/genetics ; GTPase-Activating Proteins/genetics ; GTPase-Activating Proteins/metabolism ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; Neoplasms/genetics ; RNA Interference ; RNA, Small Interfering ; Vesicular Transport Proteins/genetics ; ral GTP-Binding Proteins/genetics ; ral GTP-Binding Proteins/metabolism ; ras Proteins/genetics