المؤلفون: Itzhak, DN, Davies, C, Tyanova, S, Mishra, A, Williamson, J, Atrobus, R, Cox, J, Weekes, MP, Bomer, GHH

مصطلحات موضوعية: Proteomics, tandem mass tagging, Proteome, neurons, primary cells, LFQ, quantitative mass spectrometry, Cell Fractionation, label-free quantification, EGF signaling, Mice, Tandem Mass Spectrometry, organellar proteomics, Animals, Humans, Cells, Cultured, Organelles, Staining and Labeling, spatial proteomics, food and beverages, 3. Good health, Protein Transport, Isotope Labeling, TMT, Biomarkers, HeLa Cells, Subcellular Fractions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8758c9dda603ce80959e5528133c1f45

المؤلفون: Cho NH; Chan Zuckerberg Biohub, San Francisco, CA, USA., Cheveralls KC; Chan Zuckerberg Biohub, San Francisco, CA, USA., Brunner AD; Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Kim K; Chan Zuckerberg Biohub, San Francisco, CA, USA., Michaelis AC; Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Raghavan P; Chan Zuckerberg Biohub, San Francisco, CA, USA., Kobayashi H; Chan Zuckerberg Biohub, San Francisco, CA, USA., Savy L; Chan Zuckerberg Biohub, San Francisco, CA, USA., Li JY; Chan Zuckerberg Biohub, San Francisco, CA, USA., Canaj H; Chan Zuckerberg Biohub, San Francisco, CA, USA., Kim JYS; Chan Zuckerberg Biohub, San Francisco, CA, USA., Stewart EM; Chan Zuckerberg Biohub, San Francisco, CA, USA., Gnann C; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, Stockholm, Sweden., McCarthy F; Chan Zuckerberg Biohub, San Francisco, CA, USA., Cabrera JP; Chan Zuckerberg Biohub, San Francisco, CA, USA., Brunetti RM; Department of Biochemistry and Biophysics, University of California, San Francisco, CA, USA., Chhun BB; Chan Zuckerberg Biohub, San Francisco, CA, USA., Dingle G; Chan Zuckerberg Initiative, Redwood City, CA, USA., Hein MY; Chan Zuckerberg Biohub, San Francisco, CA, USA., Huang B; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA., Mehta SB; Chan Zuckerberg Biohub, San Francisco, CA, USA., Weissman JS; Whitehead Institute, Koch Institute, Howard Hughes Medical Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA., Gómez-Sjöberg R; Chan Zuckerberg Biohub, San Francisco, CA, USA., Itzhak DN; Chan Zuckerberg Biohub, San Francisco, CA, USA., Royer LA; Chan Zuckerberg Biohub, San Francisco, CA, USA., Mann M; Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.; NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Leonetti MD; Chan Zuckerberg Biohub, San Francisco, CA, USA.

المصدر: Science (New York, N.Y.) [Science] 2022 Mar 11; Vol. 375 (6585), pp. eabi6983. Date of Electronic Publication: 2022 Mar 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Protein Interaction Mapping*, Proteins/*metabolism , Proteome/*metabolism , Proteomics/*methods, CRISPR-Cas Systems ; Cluster Analysis ; Datasets as Topic ; Fluorescent Dyes ; HEK293 Cells ; Humans ; Immunoprecipitation ; Machine Learning ; Mass Spectrometry ; Microscopy, Confocal ; RNA-Binding Proteins/metabolism ; Spatial Analysis

المؤلفون: Kozik P; INSERM U932, PSL Research University, Institut Curie, 75005 Paris, France; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. Electronic address: pkozik@mrc-lmb.cam.ac.uk., Gros M; INSERM U932, PSL Research University, Institut Curie, 75005 Paris, France., Itzhak DN; Max Planck Institute of Biochemistry, 82152 Martinsried, Germany., Joannas L; INSERM U932, PSL Research University, Institut Curie, 75005 Paris, France., Heurtebise-Chrétien S; INSERM U932, PSL Research University, Institut Curie, 75005 Paris, France., Krawczyk PA; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Rodríguez-Silvestre P; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Alloatti A; INSERM U932, PSL Research University, Institut Curie, 75005 Paris, France., Magalhaes JG; INSERM U932, PSL Research University, Institut Curie, 75005 Paris, France., Del Nery E; Institut Curie, PSL Research University, Department of Translational Research-Biophenics High-Content Screening Laboratory, Cell and Tissue Imaging Facility (PICT-IBiSA), 75005 Paris, France., Borner GHH; Max Planck Institute of Biochemistry, 82152 Martinsried, Germany., Amigorena S; INSERM U932, PSL Research University, Institut Curie, 75005 Paris, France.

المصدر: Cell reports [Cell Rep] 2020 Jul 14; Vol. 32 (2), pp. 107905.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Immunity*/drug effects, Antineoplastic Agents/*pharmacology , Cytosol/*metabolism , Endosomes/*metabolism , Neoplasms/*immunology , Small Molecule Libraries/*pharmacology, Animals ; Antigens/metabolism ; Biological Transport/drug effects ; Cross-Priming/drug effects ; Cytosol/drug effects ; Dendritic Cells/metabolism ; Endoplasmic Reticulum-Associated Degradation/drug effects ; Endosomes/drug effects ; Mice, Inbred C57BL ; Mice, Transgenic ; Neoplasms/drug therapy ; Permeability ; Prazosin/pharmacology ; Quinazolines/pharmacology ; Tamoxifen/pharmacology ; beta-Lactamases/metabolism

المؤلفون: Chen J; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA., Brunner AD; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried 82152, Germany., Cogan JZ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA., Nuñez JK; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA., Fields AP; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA., Adamson B; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA., Itzhak DN; Cell Atlas Initiative, Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Li JY; Cell Atlas Initiative, Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Mann M; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried 82152, Germany.; Clinical Proteomics Group, Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen 2200, Denmark., Leonetti MD; Cell Atlas Initiative, Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA. jonathan.weissman@ucsf.edu.; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

المصدر: Science (New York, N.Y.) [Science] 2020 Mar 06; Vol. 367 (6482), pp. 1140-1146.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Open Reading Frames* , RNA, Messenger*/genetics , RNA, Messenger*/metabolism, Peptides/*genetics , Protein Biosynthesis/*genetics, CRISPR-Cas Systems ; Humans ; Operon ; Ribosomes/metabolism ; Transcriptome

المؤلفون: Itzhak DN; Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany., Sacco F; Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany., Nagaraj N; Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany., Tyanova S; Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany., Mann M; Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany.; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark., Murgia M; Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany mmurgia@biochem.mpg.de.; Department of Biomedical Sciences, University of Padova, 35121 Padua, Italy.

المصدر: Disease models & mechanisms [Dis Model Mech] 2019 Nov 11; Vol. 12 (11). Date of Electronic Publication: 2019 Nov 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum Stress/*physiology , Mass Spectrometry/*methods , Proteomics/*methods, Amino Acids/metabolism ; Endoplasmic Reticulum Stress/drug effects ; HeLa Cells ; Humans ; Isotope Labeling ; Protein Interaction Maps ; Thapsigargin/pharmacology ; Tunicamycin/pharmacology ; Unfolded Protein Response/drug effects

المؤلفون: Itzhak DN; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Schessner JP; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Borner GHH; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

المصدر: Current protocols in cell biology [Curr Protoc Cell Biol] 2019 Jun; Vol. 83 (1), pp. e81. Date of Electronic Publication: 2018 Nov 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Country of Publication: United States NLM ID: 101287856 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-2616 (Electronic) Linking ISSN: 19342616 NLM ISO Abbreviation: Curr Protoc Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Organelles/*metabolism , Proteomics/*methods, Intracellular Space/metabolism ; Mass Spectrometry/methods ; Organelles/ultrastructure ; Proteins/analysis ; Proteins/metabolism ; Subcellular Fractions/chemistry

المؤلفون: Davies AK; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK., Itzhak DN; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, 82152, Germany., Edgar JR; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK., Archuleta TL; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.; Center for Structural Biology, Vanderbilt University, Nashville, TN, 37235, USA., Hirst J; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK., Jackson LP; Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.; Center for Structural Biology, Vanderbilt University, Nashville, TN, 37235, USA., Robinson MS; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK. msr12@cam.ac.uk., Borner GHH; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, 82152, Germany. borner@biochem.mpg.de.

المصدر: Nature communications [Nat Commun] 2018 Sep 27; Vol. 9 (1), pp. 3958. Date of Electronic Publication: 2018 Sep 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Autophagy*, Adaptor Protein Complex 4/*metabolism , Adaptor Proteins, Signal Transducing/*metabolism , Autophagy-Related Proteins/*metabolism , Carrier Proteins/*metabolism , Membrane Proteins/*metabolism , Transport Vesicles/*metabolism , Vesicular Transport Proteins/*metabolism, HeLa Cells ; Humans ; Microtubules/metabolism ; Microtubules/ultrastructure ; Models, Biological ; Phagosomes/metabolism ; Phagosomes/ultrastructure ; Phenotype ; Protein Binding ; Proteomics ; Transport Vesicles/ultrastructure ; trans-Golgi Network/metabolism ; trans-Golgi Network/ultrastructure

المؤلفون: Szoradi T; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance and CellNetworks Cluster of Excellence, 69120 Heidelberg, Germany., Schaeff K; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance and CellNetworks Cluster of Excellence, 69120 Heidelberg, Germany., Garcia-Rivera EM; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, USA., Itzhak DN; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany., Schmidt RM; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance and CellNetworks Cluster of Excellence, 69120 Heidelberg, Germany., Bircham PW; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance and CellNetworks Cluster of Excellence, 69120 Heidelberg, Germany., Leiss K; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance and CellNetworks Cluster of Excellence, 69120 Heidelberg, Germany., Diaz-Miyar J; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance and CellNetworks Cluster of Excellence, 69120 Heidelberg, Germany., Chen VK; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, USA., Muzzey D; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Borner GHH; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany., Schuck S; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance and CellNetworks Cluster of Excellence, 69120 Heidelberg, Germany. Electronic address: s.schuck@zmbh.uni-heidelberg.de.

المصدر: Molecular cell [Mol Cell] 2018 Jun 21; Vol. 70 (6), pp. 1025-1037.e5. Date of Electronic Publication: 2018 May 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Adaptation, Physiological/*physiology , Saccharomyces cerevisiae/*metabolism , Saccharomyces cerevisiae Proteins/*metabolism , Ubiquitin-Protein Ligases/*metabolism, Cytosol/metabolism ; Endoplasmic Reticulum/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Protein Folding ; Proteolysis ; Saccharomyces cerevisiae/enzymology ; Serine Endopeptidases/metabolism ; Stress, Physiological/physiology ; Substrate Specificity ; Ubiquitin/metabolism

المؤلفون: Shurtleff MJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Itzhak DN; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Hussmann JA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Schirle Oakdale NT; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States., Costa EA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Jonikas M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Weibezahn J; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Popova KD; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Jan CH; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States., Sinitcyn P; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Vembar SS; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, United States., Hernandez H; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, United States., Cox J; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Burlingame AL; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, United States., Brodsky JL; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, United States., Frost A; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States.; Chan Zuckerberg Biohub, San Francisco, United States., Borner GH; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.

المصدر: ELife [Elife] 2018 May 29; Vol. 7. Date of Electronic Publication: 2018 May 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Protein Biosynthesis*, Endoplasmic Reticulum/*metabolism , Membrane Proteins/*metabolism , Saccharomyces cerevisiae/*metabolism, Humans ; Molecular Chaperones/metabolism ; Multiprotein Complexes/metabolism ; Protein Transport ; Proteomics ; Ribosomes/metabolism

المؤلفون: Hirst J; University of Cambridge, Cambridge Institute for Medical Research, Cambridge, United Kingdom., Itzhak DN; Max-Planck Institute of Biochemistry, Martinsried, Germany., Antrobus R; University of Cambridge, Cambridge Institute for Medical Research, Cambridge, United Kingdom., Borner GHH; Max-Planck Institute of Biochemistry, Martinsried, Germany., Robinson MS; University of Cambridge, Cambridge Institute for Medical Research, Cambridge, United Kingdom.

المصدر: PLoS biology [PLoS Biol] 2018 Jan 30; Vol. 16 (1), pp. e2004411. Date of Electronic Publication: 2018 Jan 30 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Vesicular Transport/*genetics , Adaptor Proteins, Vesicular Transport/*physiology, Adaptor Proteins, Vesicular Transport/metabolism ; CRISPR-Cas Systems ; Endosomes/physiology ; Golgi Apparatus/physiology ; HeLa Cells ; Humans ; Lysosomes/genetics ; Lysosomes/physiology ; Mass Spectrometry ; Membrane Proteins/metabolism ; Phenotype ; Protein Transport ; Spastic Paraplegia, Hereditary/genetics ; Vesicular Transport Proteins/metabolism