نتائج البحث - "J Lori Blanchfield"

1

Inhibition of Polyamine Biosynthesis Preserves β Cell Function in Type 1 Diabetes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf194459eb879a9aed256fcf023d33bd
https://doi.org/10.2139/ssrn.4417788

2

Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA1c, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data

المصدر: Diabetes

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, T cell, CD4-CD8 Ratio, 030209 endocrinology & metabolism, Placebo, T-Lymphocytes, Regulatory, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Double-Blind Method, Internal medicine, Diabetes mellitus, Granulocyte Colony-Stimulating Factor, Internal Medicine, medicine, Humans, Immunologic Factors, Child, Antilymphocyte Serum, Glycated Hemoglobin, Type 1 diabetes, C-Peptide, C-peptide, business.industry, Area under the curve, medicine.disease, Flow Cytometry, Anti-thymocyte globulin, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Diabetes Mellitus, Type 1, chemistry, Female, Immunology and Transplantation, business, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e408ecd37f3201a76d7f54cd07b1a446
http://europepmc.org/articles/PMC6610026

3

Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

المؤلفون: Stephen E Gitelman, Brian N Bundy, Ele Ferrannini, Noha Lim, J Lori Blanchfield, Linda A DiMeglio, Eric I Felner, Jason L Gaglia, Peter A Gottlieb, S Alice Long, Andrea Mari, Raghavendra G Mirmira, Philip Raskin, Srinath Sanda, Eva Tsalikian, John M Wentworth, Steven M Willi, Jeffrey P Krischer, Jeffrey A Bluestone, Mayalin Barr, Jeanne Buchanan, Joanne Cabbage, Peter Coleman, Monica De La Vega, Carmella Evans-Molina, Christine Ferrara, Felicity Healy, Laurie Higgins, Megan Hildinger, Margaret Jenkins, Nora Kayton Bryant, Amanda Kinderman, Nisha Koshy, Brianne Kost, Suzanne Krishfield, Olena Kucheruk, Karen Lindsley, Manasa Mantravadi, Shelley Mesfin, Aaron Michels, Mary Ellen Migre, Pantea Minnock, Elham Mohammed-Nur, Jennifer Nelson, Ashvin Nursing, Ryan O'Donnell, Diana Olivos, Melissa Parker, Leanne Redl, Nicole Reed, Brittany Resnick, Peter Sayre, Elisavet Serti, Emily Sims, Karen Smith, Carol Soppe, Fiona Stuart, Sarah Szubowicz, Michel Tansey, Jennifer Terrell, Sarah Tersey, Christine Torok, Kelly Watson, Rebecca Wesch, Steven Willi, Stephanie Woerner

المصدر: Lancet Diabetes Endocrinol

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Population, 030209 endocrinology & metabolism, Placebo, Article, law.invention, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Endocrinology, Randomized controlled trial, Double-Blind Method, law, Internal medicine, Internal Medicine, Clinical endpoint, Medicine, Humans, 030212 general & internal medicine, education, Adverse effect, Protein Kinase Inhibitors, Type 1 diabetes, education.field_of_study, business.industry, Middle Aged, medicine.disease, Prognosis, Discontinuation, Clinical trial, Diabetes Mellitus, Type 1, Imatinib Mesylate, Female, business, Biomarkers, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc88b8333d4324e0044265eff7356ed
https://pubmed.ncbi.nlm.nih.gov/34214480

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4

Imatinib Therapy for Patients with Recent-Onset Type 1 Diabetes: A Randomised Blinded Phase 2 Trial

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Type 1 diabetes, medicine.medical_specialty, Intention-to-treat analysis, business.industry, Area under the curve, medicine.disease, Placebo, Clinical trial, Internal medicine, Diabetes mellitus, Good clinical practice, medicine, Clinical endpoint, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0cbcbbc4adabd32b1b02c235995f21c8
https://doi.org/10.2139/ssrn.3773520

5

دورية أكاديمية

Cytokine-neuroantigen fusion proteins as a new class of tolerogenic, therapeutic vaccines for treatment of inflammatory demyelinating disease in rodent models of multiple sclerosis

المؤلفون: Mark D. Mannie, J. Lori Blanchfield, S. M. Touhidul eIslam, Derek J. Abbott

المصدر: Frontiers in Immunology, Vol 3 (2012)

مصطلحات موضوعية: Interferon-beta, Multiple Sclerosis, Experimental autoimmune encephalomyelitis, immunological tolerance, autoimmune demyelination, cytokine-antigen fusion protein, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00255/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/80f17742a4f7415bb4cc76b0daed707a

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6

Monitoring the Dynamics of T cell Clonal Diversity using Recombinant Peptide:MHC Technology

المؤلفون: J. Lori Blanchfield, Brian D. Evavold, Shayla Shorter

المصدر: Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2171c18f0aee391d1d49ed881f99f6b
http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00170/full

7

Autoimmune T cells binds to self antigen weakly in the thymus but greatly upregulate the binding strength in the periphery

المؤلفون: Baoyu Liu, J. Lori Blanchfield, Cheng Zhu, Brian D. Evavold

المصدر: The Journal of Immunology. 196:54.15-54.15

مصطلحات موضوعية: Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7b62f37b4e603be67bf1a4b4a3d5d69b
https://doi.org/10.4049/jimmunol.196.supp.54.15

8

Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE)

المؤلفون: Alan D. Curtis, David A. Martinson, Derek J. Abbott, Najla Taslim, Mark D. Mannie, J. Lori Blanchfield, Sean C. Russell

المصدر: BMC Immunology
BMC Immunology, Vol 12, Iss 1, p 72 (2011)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Recombinant Fusion Proteins, Immunology, Biology, Autoantigens, Nervous System, Myelin oligodendrocyte glycoprotein, Immune tolerance, 03 medical and health sciences, Myelin, Mice, 0302 clinical medicine, Immunity, immune system diseases, medicine, Immune Tolerance, Animals, Humans, 030304 developmental biology, Glycoproteins, Autoimmune disease, 0303 health sciences, Immunodominant Epitopes, Multiple sclerosis, Experimental autoimmune encephalomyelitis, Granulocyte-Macrophage Colony-Stimulating Factor, medicine.disease, Fusion protein, Peptide Fragments, 3. Good health, nervous system diseases, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Vaccines, Subunit, biology.protein, Disease Progression, Myelin-Oligodendrocyte Glycoprotein, lcsh:RC581-607, 030215 immunology, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f75cad6da68b98bc3ff5cfacadd292
https://pubmed.ncbi.nlm.nih.gov/22208499

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9

A GMCSF-neuroantigen fusion protein is a potent tolerogen in experimental autoimmune encephalomyelitis (EAE) that is associated with efficient targeting of neuroantigen to APC

المؤلفون: J. Lori Blanchfield, Mark D. Mannie

المصدر: Journal of leukocyte biology. 87(3)

مصطلحات موضوعية: Macrophage colony-stimulating factor, Encephalomyelitis, Autoimmune, Experimental, medicine.medical_treatment, T cell, Recombinant Fusion Proteins, Immunology, Guinea Pigs, Antigen-Presenting Cells, Translational & Clinical Immunology, Biology, urologic and male genital diseases, Mice, Antigen, medicine, Immunology and Allergy, Animals, Antigens, Organic Chemicals, Antigen-presenting cell, B cell, urogenital system, Macrophage Colony-Stimulating Factor, Experimental autoimmune encephalomyelitis, Granulocyte-Macrophage Colony-Stimulating Factor, Cell Differentiation, Myelin Basic Protein, Cell Biology, medicine.disease, Fusion protein, Protein Structure, Tertiary, Rats, medicine.anatomical_structure, Cytokine, Organ Specificity, Disease Progression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a676758c4b3b450b42e0a1064d80574c
https://pubmed.ncbi.nlm.nih.gov/20007248

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10

Experimental autoimmune encephalomyelitis in Lewis rats: IFN-beta acts as a tolerogenic adjuvant for induction of neuroantigen-dependent tolerance

المؤلفون: Mark D. Mannie, J. Lori Blanchfield, Derek J. Abbott

المصدر: Journal of immunology (Baltimore, Md. : 1950). 182(9)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047b349bc42c3c67b1fb5cc00f21222b
https://pubmed.ncbi.nlm.nih.gov/19380780

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