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المؤلفون: Ragnhild A. Lothe, Maren Høland, Olli Kallioniemi, J P Mpindi, Ina A. Eilertsen, Astrid Murumägi, Stine A. Danielsen, Christian H. Bergsland, Matthias Kolberg, Jarle Bruun
المساهمون: Institute for Molecular Medicine Finland, University of Helsinki, Olli-Pekka Kallioniemi / Principal Investigator, Precision Systems Medicine
المصدر: Molecular Oncology
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pathology, Apoptosis, Cell Cycle Proteins, Deoxycytidine, Nerve Sheath Neoplasms, drug screen, chemistry.chemical_compound, 0302 clinical medicine, Neurofibroma, KINASE 1, Research Articles, Clinical Trials as Topic, Volasertib, General Medicine, Schwann cell, 3. Good health, Gene Expression Regulation, Neoplastic, SOFT-TISSUE SARCOMA, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, PHASE-II, GROWTH, Molecular Medicine, Research Article, medicine.drug, CANCER-THERAPY, medicine.medical_specialty, Ribonucleoside Diphosphate Reductase, 3122 Cancers, Malignant peripheral nerve sheath tumor, Protein Serine-Threonine Kinases, Biology, SCHWANNOMA CELL-LINE, 03 medical and health sciences, MPNST, Cell Line, Tumor, Proto-Oncogene Proteins, Genetics, Adjuvant therapy, medicine, Humans, Protein Kinase Inhibitors, Tumor Suppressor Proteins, Reproducibility of Results, Cancer, NEUROFIBROMATOSIS TYPE-1 PATIENTS, IN-VITRO, medicine.disease, Gemcitabine, GENE, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Cell culture, Cancer research, pharmacology, RAS
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المؤلفون: Pekka Ellonen, Dorine Bellanger, Jing Tang, Bhagwan Yadav, Emma I. Andersson, J P Mpindi, Olli Dufva, Samuli Eldfors, Wei Ding, Katarzyna Tomska, Marc-Henri Stern, Tea Pemovska, Carlos Cuesta-Mateos, Anneli Lauhio, Henan Zhang, Satu Mustjoki, T H Brümmendorf, Krister Wennerberg, Steffen Koschmieder, Giuliano Crispatzu, Alexandra Schrader, Soili Kytölä, Shady Adnan-Awad, Leopold Sellner, Marco Herling, Edgar Faber, Olli Kallioniemi, Małgorzata Oleś, S. Pützer, Sofia Khan, Sonja Lagström, Liye He, Timo Siitonen, Eeva-Riitta Savolainen, Paavo Pietarinen, Simon Anders, Tero Aittokallio, Wolfgang Huber, Thorsten Zenz
المصدر: Leukemia
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Gene Expression, Drug resistance, Pharmacology, medicine.disease_cause, 0302 clinical medicine, Molecular Targeted Therapy, Prolymphocytic leukemia, Oxazoles, media_common, Aged, 80 and over, Mutation, Cell Cycle, Hematology, Middle Aged, 3. Good health, STAT Transcription Factors, Phenotype, Oncology, 030220 oncology & carcinogenesis, Female, Drug, media_common.quotation_subject, Antineoplastic Agents, Biology, 03 medical and health sciences, Cell Line, Tumor, Biomarkers, Tumor, medicine, Humans, Protein Kinase Inhibitors, Protein kinase B, Aged, Janus Kinases, Chromosome Aberrations, Gene Expression Profiling, medicine.disease, ta3122, High-Throughput Screening Assays, Gene expression profiling, Thiazoles, 030104 developmental biology, Drug Resistance, Neoplasm, Leukemia, Prolymphocytic, T-Cell, Histone deacetylase, Drug Screening Assays, Antitumor, Ex vivo
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المؤلفون: Yuanyuan Zhang, Arindam Majumdar, Sophie Petropoulos, Lars Holmgren, Sebastian Hildebrand, Fredrik Lanner, J P Mpindi, Xiaofang Cao, Sara Hultin, Olli Kalloniemi, Aravindh Subramani, Staffan Johansson
المساهمون: Institute for Molecular Medicine Finland, Olli-Pekka Kallioniemi / Principal Investigator, University of Helsinki, Precision Systems Medicine
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Scientific Reports
Hildebrand, S, Hultin, S, Subramani, A, Petropoulos, S, Zhang, Y, Cao, X, Mpindi, J, Kalloniemi, O, Johansson, S, Majumdar, A, Lanner, F & Holmgren, L 2017, ' The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching ', Scientific Reports, vol. 7, no. 1, 9540 . https://doi.org/10.1038/s41598-017-10102-wمصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, ANGIOMOTIN, Gene Expression, lcsh:Medicine, Cell junction, Epithelium, Gene Knockout Techniques, Mice, Myosin, lcsh:Science, Zebrafish, Skin, Multidisciplinary, EMBRYO, Cadherins, MOUSE BLASTOCYSTS, Cell biology, Actin Cytoskeleton, medicine.anatomical_structure, Intercellular Junctions, embryonic structures, Protein Binding, POLARITY, CELL-CELL ADHESION, Cellbiologi, Biology, Article, Cell Line, Adherens junction, 03 medical and health sciences, FAMILY PROTEINS, E-CADHERIN, medicine, Animals, Humans, Blastocyst, Actin, Cadherin, lcsh:R, ADHERENS JUNCTIONS, Epithelial Cells, Cell Biology, Actin cytoskeleton, ENDOTHELIAL-CELLS, 030104 developmental biology, Angiomotins, Multiprotein Complexes, lcsh:Q, Stress, Mechanical, 3111 Biomedicine, Carrier Proteins, MATRIX
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a633b8333e5b272374140b7b733dd5
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-339873 -
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المؤلفون: Emma I. Andersson, Christopher A. Eide, Brian J. Druker, Tea Pemovska, Satu Mustjoki, Olli Kallioniemi, Kimmo Porkka, Swapnil Potdar, Caroline A. Heckman, Paavo Pietarinen, Jorrit M. Enserink, Henrik Hjorth-Hansen, Heikki Kuusanmäki, Mika Kontro, J P Mpindi, Krister Wennerberg, Pilar Ayuda-Durán, Jeffrey W. Tyner
المساهمون: Clinicum, University of Helsinki, Hematologian yksikkö, Department of Oncology, Medicum, Department of Clinical Chemistry and Hematology, Institute for Molecular Medicine Finland, Olli-Pekka Kallioniemi / Principal Investigator, Krister Wennerberg / Principal Investigator, Department of Diagnostics and Therapeutics, HUS Comprehensive Cancer Center, Precision Systems Medicine
المصدر: 22606-22615
OncoTarget
Oncotargetمصطلحات موضوعية: 0301 basic medicine, Oncology, Fusion Proteins, bcr-abl, Apoptosis, Cohort Studies, 0302 clinical medicine, hemic and lymphatic diseases, tyrosine kinase inhibitors, Tumor Cells, Cultured, education.field_of_study, DASATINIB, Hematology, CHRONIC MYELOGENOUS LEUKEMIA, Myeloid leukemia, Cell Differentiation, 3. Good health, Dasatinib, Leukemia, 030220 oncology & carcinogenesis, STEM-CELLS, medicine.drug, Research Paper, medicine.medical_specialty, Population, 3122 Cancers, IMATINIB, MECHANISMS, 03 medical and health sciences, DRUG-SENSITIVITY, chronic myeloid leukemia, Internal medicine, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, medicine, Biomarkers, Tumor, Humans, education, Protein Kinase Inhibitors, Cell Proliferation, business.industry, high-throughput drug screening, Cancer, CRKL, Imatinib, medicine.disease, High-Throughput Screening Assays, respiratory tract diseases, 030104 developmental biology, Drug Resistance, Neoplasm, Immunology, ex vivo, CD34, business, RESISTANCE, Chronic myelogenous leukemia
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bece82d73c36b50e127136d2aaaee06d
https://hdl.handle.net/11250/2779863 -
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المؤلفون: Arild Nesbakken, Sami Kilpinen, Olli Kallioniemi, Jarle Bruun, Mette Eknæs, Marthe Løvf, Ragnhild A. Lothe, Torfinn Nome, Torleiv O. Rognum, Anne Cathrine Bakken, Rolf Inge Skotheim, J P Mpindi
المصدر: International Journal of Cancer. 135:2077-2084
مصطلحات موضوعية: Oncology, 0303 health sciences, Cancer Research, medicine.medical_specialty, Colorectal cancer, Alternative splicing, Disease, Biology, medicine.disease, 3. Good health, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Rapid amplification of cDNA ends, 030220 oncology & carcinogenesis, Internal medicine, medicine, Biomarker (medicine), Stage (cooking), Gene, 030304 developmental biology
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المؤلفون: Cecilia Sahlgren, Olli-Pekka Kallioniemi, Indira V. Chivukula, Pauliina Kronqvist, Daniel Ramsköld, Emma R. Andersson, Kian Leong Lee, Veronika Mamaeva, J-P Mpindi, Päivi Östling, Urban Lendahl, Lorenz Poellinger, Shaobo Jin, Isabella Screpanti, Rickard Sandberg, Anders P. Mutvei
المصدر: Oncogene
مصطلحات موضوعية: Cancer Research, Notch signaling pathway, Breast Neoplasms, Biology, ta3111, 03 medical and health sciences, Paracrine signalling, 0302 clinical medicine, breast cancer, Cell Line, Tumor, Paracrine Communication, Genetics, cytokine, Humans, RNA, Messenger, Autocrine signalling, Molecular Biology, 030304 developmental biology, Janus Kinases, 0303 health sciences, Receptors, Notch, Interleukin-6, Macrophages, BCL, tumor stroma, I-kappa B Kinase, Up-Regulation, Gene Expression Regulation, Neoplastic, Autocrine Communication, STAT Transcription Factors, Notch proteins, Hes3 signaling axis, inflammation, 030220 oncology & carcinogenesis, Cancer research, Cyclin-dependent kinase 8, Original Article, bcl, estrogen receptor, Signal transduction, Tumor Suppressor Protein p53, Janus kinase, Transcriptome, Signal Transduction
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المؤلفون: Minna Niemelä, Daniel Nicorici, Heikki Joensuu, Olli Kallioniemi, Jukka Westermarck, Otto Kauko, Harri Sihto, Sampsa Hautaniemi, P. Pernilä, J P Mpindi
المصدر: Oncogene. 31:4266-4278
مصطلحات موضوعية: Cancer Research, Receptor, ErbB-2, Breast Neoplasms, Biology, Autoantigens, Molecular oncology, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Growth factor receptor, Tumor Cells, Cultured, Genetics, medicine, Humans, Mitogen-Activated Protein Kinase 9, Protein Phosphatase 2, RNA, Small Interfering, skin and connective tissue diseases, Molecular Biology, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Gene Expression Profiling, ta1182, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Cancer, Cell cycle, medicine.disease, Phenotype, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Cancer research, Female, Signal Transduction
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المؤلفون: Marjut Puputti, Saija Haapa-Paananen, Heikki Joensuu, Pekka Kohonen, Marika Waltari, Olli Kallioniemi, Hannu Haapasalo, Olli Tynninen, Merja Perälä, Kiviluoto S, J P Mpindi
المصدر: Haapa-Paananen, S, Kiviluoto, S, Waltari, M, Puputti, M, Mpindi, J, Kohonen, P, Tynninen, O, Haapasalo, H, Joensuu, H, Perälä, M & Kallioniemi, O 2012, ' HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation ', Oncogene, vol. 31, no. 10, pp. 1299-1310 . https://doi.org/10.1038/onc.2011.316
مصطلحات موضوعية: Cancer Research, Receptor, Platelet-Derived Growth Factor alpha, Transcription, Genetic, Gene Dosage, Genes, myc, Biology, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Cell Movement, glioma, Glioma, Cell Line, Tumor, Genetics, medicine, Transcriptional regulation, Basic Helix-Loop-Helix Transcription Factors, Humans, TMA, astrocytoma, neoplasms, Molecular Biology, Gene, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Brain Neoplasms, glioblastoma, medicine.disease, Vascular Endothelial Growth Factor Receptor-2, nervous system diseases, 3. Good health, ErbB Receptors, Repressor Proteins, RNAi, 030220 oncology & carcinogenesis, Cancer research, HES6
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المؤلفون: Olli-Pekka Kallioniemi, Antti Rannikko, Matthias Nees, Tiina Vesterinen, Anna Sankila, J P Mpindi, Pekka Kohonen, Ville Härmä, Mari Björkman, Johannes Virtanen, E Kaivanto, Mikael Lundin, Juha Rantala, Päivi Östling, Tuomas Mirtti
المصدر: Björkman, M, Östling, P, Härmä, V, Virtanen, J, Mpindi, J, Rantala, J K, Mirtti, T, Vesterinen, T, Lundin, M, Sankila, A, Rannikko, A, Kaivanto, E, Kohonen, P, Kallioniemi, O & Nees, M 2011, ' Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion ', Oncogene, vol. 31, no. 29, pp. 3444-3456 . https://doi.org/10.1038/onc.2011.512
مصطلحات موضوعية: Adult, Male, Cancer Research, Jumonji Domain-Containing Histone Demethylases, Epigenetic regulation of neurogenesis, Biology, ta3111, Histone Deacetylases, Epigenesis, Genetic, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Cell Movement, Histone methylation, Genetics, Humans, Neoplasm Invasiveness, Epigenetics, Cancer epigenetics, Molecular Biology, 030304 developmental biology, Epigenomics, Aged, Cell Proliferation, Regulation of gene expression, Aged, 80 and over, Histone Demethylases, 0303 health sciences, Prostatic Neoplasms, Epigenome, Middle Aged, Molecular biology, 3. Good health, Gene Expression Regulation, Neoplastic, Receptors, Androgen, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Cancer research, biology.protein, Demethylase, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d636b391b1408fa7f1a31ed7e81ccce8
https://cris.vtt.fi/en/publications/558a95f2-a770-4a25-a5af-6e35304c31f1 -
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المؤلفون: Olli Kallioniemi, Emma I. Andersson, Mika Kontro, Muntasir Mamun Majumder, Tea Pemovska, Heikki Kuusanmäki, Perttu Koskenvesa, Bhagwan Yadav, Krister Wennerberg, Satu Mustjoki, Caroline A. Heckman, Kimmo Porkka, Paavo Pietarinen, J P Mpindi
المصدر: Blood Cancer Journal
مصطلحات موضوعية: Adult, Drug, Cell Survival, medicine.drug_class, media_common.quotation_subject, Nicotinamide phosphoribosyltransferase, Antineoplastic Agents, Drug resistance, Pharmacology, Tyrosine-kinase inhibitor, chemistry.chemical_compound, Cell Line, Tumor, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, Humans, Medicine, media_common, business.industry, Myeloid leukemia, Imatinib, Hematology, medicine.disease, High-Throughput Screening Assays, 3. Good health, Leukemia, Oncology, chemistry, Drug Resistance, Neoplasm, Cancer research, Original Article, Drug Screening Assays, Antitumor, Blast Crisis, business, K562 cells, medicine.drug
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