المؤلفون: Rachel Waller, Lynne Baxter, Daniel J Fillingham, Santiago Coelho, Jose M Pozo, Meghdoot Mozumder, Alejandro F Frangi, Paul G Ince, Julie E Simpson, J Robin Highley

المصدر: PLoS ONE, Vol 14, Iss 1, p e0210888 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/bf9ba81364ba489bb1902dc093d4234a

المؤلفون: Penelope J Boyd, Wen-Yo Tu, Hannah K Shorrock, Ewout J N Groen, Roderick N Carter, Rachael A Powis, Sophie R Thomson, Derek Thomson, Laura C Graham, Anna A L Motyl, Thomas M Wishart, J Robin Highley, Nicholas M Morton, Thomas Becker, Catherina G Becker, Paul R Heath, Thomas H Gillingwater

المصدر: PLoS Genetics, Vol 13, Iss 4, p e1006744 (2017)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5417717?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/6a1994812232441a91ce50a3acc16685

المؤلفون: Johnathan Cooper-Knock, Joanna J Bury, Paul R Heath, Matthew Wyles, Adrian Higginbottom, Catherine Gelsthorpe, J Robin Highley, Guillaume Hautbergue, Magnus Rattray, Janine Kirby, Pamela J Shaw

المصدر: PLoS ONE, Vol 10, Iss 5, p e0127376 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4446097?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/aff9c496bb584987a02025675ad67a26

المؤلفون: Scott P. Allen, Afnan Al Sultan, Elaine Kabucho Kibirige, Erin Tonkiss, Keaton J. Hamer, Lydia M. Castelli, Ya-Hui Lin, Sarah Roscoe, Nikolaos Stefanidis, Richard J. Mead, J. Robin Highley, Johnathan Cooper-Knock, Guillaume M. Hautbergue, Paul R. Heath, Janine Kirby, Pamela J. Shaw

المصدر: Frontiers in Aging Neuroscience, Vol 15 (2023)

مصطلحات موضوعية: ALS, fibroblasts, metabolism, pyruvate, TCA, transcriptomics, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1151848/full; https://doaj.org/toc/1663-4365

URL الوصول: https://doaj.org/article/ca2ad4e34a5b4061a9d5da2449950735

المؤلفون: Claudia S. Bauer, Rebecca N. Cohen, Francesca Sironi, Matthew R. Livesey, Thomas H. Gillingwater, J. Robin Highley, Daniel J. Fillingham, Ian Coldicott, Emma F. Smith, Yolanda B. Gibson, Christopher P. Webster, Andrew J. Grierson, Caterina Bendotti, Kurt J. De Vos

المصدر: Bauer, C S, Cohen, R N, Sironi, F, Livesey, M R, Gillingwater, T H, Highley, J R, Fillingham, D J, Coldicott, I, Smith, E F, Gibson, Y B, Webster, C P, Grierson, A J, Bendotti, C & De Vos, K J 2022, ' An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD ', Acta Neuropathologica, vol. 144, pp. 437–464 .

مصطلحات موضوعية: synapsin, Mice, Knockout, amyotrophic lateral sclerosis, DNA Repeat Expansion, C9orf72 Protein, Amyotrophic Lateral Sclerosis, Synapsins, frontotemporal dementia, Pathology and Forensic Medicine, Mice, Cellular and Molecular Neuroscience, synapse, Frontotemporal Dementia, C9orf72, Synapses, Animals, Neurology (clinical)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62b958cdd3f8be1dbf86bcad7b19440
https://doi.org/10.1007/s00401-022-02470-z

المؤلفون: Bridget C. Benson, Pamela J. Shaw, Mimoun Azzouz, J. Robin Highley, Guillaume M. Hautbergue

المصدر: Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)

مصطلحات موضوعية: RNA metabolism alteration, amyotrophic lateral sclerosis, proteinopathies, General Neuroscience, mitochondrial dysfunction, Neurosciences. Biological psychiatry. Neuropsychiatry, Review, impaired proteostasis, RC321-571, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbca752fc9ccf2342ff0910cacb4760

المؤلفون: Johnathan Cooper‐Knock, Thomas H. Julian, Emily Feneberg, J. Robin Highley, Maurice Sidra, Martin R. Turner, Kevin Talbot, Olaf Ansorge, Scott P. Allen, Tobias Moll, Tatyana Shelkovnikova, Lydia Castelli, Guillaume M. Hautbergue, Christopher Hewitt, Janine Kirby, Stephen B. Wharton, Richard J. Mead, Pamela J. Shaw

المصدر: Brain pathology (Zurich, Switzerland)REFERENCES.

مصطلحات موضوعية: General Neuroscience, Neurology (clinical), Pathology and Forensic Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3aa72d2fe38ff324a9cd76f5c9d738
https://pubmed.ncbi.nlm.nih.gov/35871544

المؤلفون: Heather Mortiboys, J. Robin Highley, Julie E. Simpson, Guillaume M. Hautbergue, Oliver Bandmann, Karla L. Robles López, Lisa Watson

المصدر: Brain Research. 1706:218-223

مصطلحات موضوعية: Lewy Body Disease, Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Parkinson's disease, Cytoplasmic inclusion, Substantia nigra, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Atrophy, Neurites, medicine, Humans, Motor Neuron Disease, Molecular Biology, Aged, Aged, 80 and over, Inclusion Bodies, Neurons, Alpha-synuclein, Lewy body, Dementia with Lewy bodies, business.industry, General Neuroscience, Brain, Parkinson Disease, Middle Aged, Multiple System Atrophy, medicine.disease, Immunohistochemistry, Phosphoric Monoester Hydrolases, Substantia Nigra, 030104 developmental biology, chemistry, alpha-Synuclein, Dementia, Female, Lewy Bodies, Neurology (clinical), Apoptosis Regulatory Proteins, business, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd32a6f48c2a9ec867674bff16dfd09
https://doi.org/10.1016/j.brainres.2018.09.032

المؤلفون: Pamela J. Shaw, Johnathan Cooper-Knock, Adrian Higginbottom, Janine Kirby, Jonathan D. Wood, Ebtisam Al-ofi, Alejandro Lorente Pons, J. Robin Highley, Aziza Alrafiah

المصدر: Lorente Pons, A, Higginbottom, A, Cooper-Knock, J, Alrafiah, A, Alofi, E, Kirby, J, Shaw, P J, Wood, J D & Highley, J R 2020, ' Oligodendrocyte pathology exceeds axonal pathology in white matter in human amyotrophic lateral sclerosis ', Journal of Pathology . https://doi.org/10.1002/path.5455

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, amyotrophic lateral sclerosis, Neurofilament, Axonal loss, post-mortem RNA transport, Pyramidal Tracts, RNA Transport, Pathology and Forensic Medicine, 03 medical and health sciences, Myelin, motor neurone disease, 0302 clinical medicine, C9orf72, Heterogeneous-Nuclear Ribonucleoprotein Group A-B, Sequestosome-1 Protein, medicine, MRNA transport, Humans, Genetic Predisposition to Disease, RNA, Messenger, Amyotrophic lateral sclerosis, axon, biology, C9orf72 Protein, Amyotrophic Lateral Sclerosis, Myelin Basic Protein, medicine.disease, White Matter, Oligodendrocyte, Axons, Myelin basic protein, DNA-Binding Proteins, myelin, Oligodendroglia, 030104 developmental biology, medicine.anatomical_structure, Phenotype, 030220 oncology & carcinogenesis, Case-Control Studies, Mutation, biology.protein, Autopsy, oligodendrocyte, Biomarkers, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d482a6df36217c0955f28663b5d9b0
https://pubmed.ncbi.nlm.nih.gov/32391572

المؤلفون: Paul R. Heath, Wen-Yo Tu, J. Robin Highley, Julie E. Simpson

المصدر: Neurobiology of Disease, Vol 102, Iss, Pp 11-20 (2017)

مصطلحات موضوعية: 0301 basic medicine, Selective vulnerability, Degeneration (medical), Disease, lcsh:RC321-571, Muscular Atrophy, Spinal, 03 medical and health sciences, 0302 clinical medicine, Motor neurone disease, medicine, Animals, Humans, SMA, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Pathological, Motor Neurons, Muscle weakness, Spinal muscular atrophy, medicine.disease, Spinal cord, Disease modifier, SMN, 030104 developmental biology, medicine.anatomical_structure, Neurology, medicine.symptom, Psychology, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a879935f06b02a6667f88d15aa563715
https://doi.org/10.1016/j.nbd.2017.01.011