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1
المؤلفون: A. T. Cohen, Rebecca A. Boyd, Lorenzo DiCarlo, Raphael Pak, J. W. Mandema
المصدر: Journal of Thrombosis and Haemostasis. 11:1503-1510
مصطلحات موضوعية: Adult, Male, Pyrrolidines, medicine.drug_mechanism_of_action, Pyridones, Factor Xa Inhibitor, Total knee replacement, Venography, Administration, Oral, Phases of clinical research, Thromboembolism, medicine, Humans, Computer Simulation, Enoxaparin, Arthroplasty, Replacement, Knee, Aged, Probability, Aged, 80 and over, Dose-Response Relationship, Drug, medicine.diagnostic_test, business.industry, Hematology, Middle Aged, Dose-ranging study, Dose–response relationship, Treatment Outcome, Anesthesia, Adaptive design, Female, business, Venous thromboembolism, Factor Xa Inhibitors
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2
المؤلفون: Rebecca A. Boyd, Lorenzo DiCarlo, J W Mandema
المصدر: Clinical Pharmacology & Therapeutics. 90:820-827
مصطلحات موضوعية: Pharmacology, Drug, medicine.medical_specialty, Clinical pharmacology, business.industry, media_common.quotation_subject, Surgery, law.invention, Therapeutic index, Drug development, Randomized controlled trial, law, Internal medicine, Meta-analysis, Orthopedic surgery, medicine, Pharmacology (medical), business, Venous thromboembolism, media_common
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3
المؤلفون: J. W. Mandema, B. Tuk, Meindert Danhof
المصدر: Journal of Pharmacokinetics and Biopharmaceutics. 25:39-62
مصطلحات موضوعية: Pharmacokinetics, Venous sampling, Pharmacodynamics, Statistics, Effect site, Range (statistics), Arterial blood, Pharmacology (medical), General Pharmacology, Toxicology and Pharmaceutics, Effect compartment, Link model, Mathematics
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4
المؤلفون: Steven W. Martin, Samuel H. Zwillich, J W Mandema, P H van der Graaf, Peter A. Milligan, G Nucci, Don Nichols, Richard L. Lalonde, Neil Benson, Thomas C. Stock, Rebecca A. Boyd, David Gruben, B Marchant, R.J. Anziano, M.J. Brown, Sriram Krishnaswami
المصدر: Clinical pharmacology and therapeutics. 93(6)
مصطلحات موضوعية: Pharmacology, Clinical Trials as Topic, Operations research, Drug Industry, business.industry, Context (language use), Investment (macroeconomics), Phase (combat), Models, Biological, Total investment, Risk analysis (engineering), Drug development, Drug Discovery, Medicine, Humans, Pharmacology (medical), Computer Simulation, business, Set (psychology), Productivity, Pharmaceutical industry
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5
المؤلفون: J W Mandema, Rebecca A. Boyd, Megan A. Gibbs, D R Wada, M Pfister
المصدر: Clinical pharmacology and therapeutics. 90(6)
مصطلحات موضوعية: Pharmacology, business.industry, Antibodies, Monoclonal, Anticoagulants, Venous Thromboembolism, Arthritis, Rheumatoid, Drug development, Risk analysis (engineering), Meta-analysis, Antirheumatic Agents, Existing Treatment, Medicine, Humans, Pharmacology (medical), Orthopedic Procedures, business
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6A dose-response meta-analysis for quantifying relative efficacy of biologics in rheumatoid arthritis
المؤلفون: David H. Salinger, Megan A. Gibbs, Scott Baumgartner, J W Mandema
المصدر: Clinical pharmacology and therapeutics. 90(6)
مصطلحات موضوعية: musculoskeletal diseases, Oncology, medicine.medical_specialty, Arthritis, Pharmacology, law.invention, Etanercept, Arthritis, Rheumatoid, Randomized controlled trial, law, Internal medicine, medicine, Adalimumab, Humans, Pharmacology (medical), skin and connective tissue diseases, Randomized Controlled Trials as Topic, Biological Products, Dose-Response Relationship, Drug, business.industry, Tumor Necrosis Factor-alpha, Antibodies, Monoclonal, medicine.disease, Rheumatology, Infliximab, Golimumab, Rheumatoid arthritis, Antirheumatic Agents, business, medicine.drug
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7
المؤلفون: A. Hoogerkamp, J. W. Mandema, R. A. A. Mathôt, Meindert Danhof
المساهمون: Other departments
المصدر: European journal of drug metabolism and pharmacokinetics, 18(1), 41-47. Springer Paris
مصطلحات موضوعية: Pharmacology, Intravenous dose, Pharmacokinetic pharmacodynamic, Chemistry, Drug Evaluation, Preclinical, Human physiology, Serum concentration, Models, Biological, Rats, GABAergic Agonist, Pharmacokinetics, Pharmacodynamics, Time course, Animals, Humans, Pharmacology (medical)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea70147d4988193b0838a9c331c1fb3
https://doi.org/10.1007/bf03220007 -
8
المؤلفون: C J, Bol, J P, Vogelaar, J P, Tang, J W, Mandema
المصدر: The Journal of pharmacology and experimental therapeutics. 294(1)
مصطلحات موضوعية: Male, Anti-Anxiety Agents, Dose-Response Relationship, Drug, Heart Rate, Midazolam, Animals, Blood Pressure, Drug Interactions, Electroencephalography, Rats, Wistar, Adrenergic alpha-Agonists, Dexmedetomidine, Rats
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::80f7833a4ffa6b50ec8de6fd8f202f0f
https://pubmed.ncbi.nlm.nih.gov/10871332 -
9
المؤلفون: C J, Bol, J P, Vogelaar, J W, Mandema
المصدر: The Journal of pharmacology and experimental therapeutics. 291(1)
مصطلحات موضوعية: Male, Heart Rate, Imidazoles, Animals, Electroencephalography, Analgesics, Non-Narcotic, Medetomidine, Rats, Wistar, Cardiovascular System, Pain Measurement, Rats
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::899cdffdbfa581f7ced033502b15af6f
https://pubmed.ncbi.nlm.nih.gov/10490899 -
10
المؤلفون: Bol CJJG, M, Danhof, D R, Stanski, J W, Mandema
المصدر: The Journal of pharmacology and experimental therapeutics. 283(3)
مصطلحات موضوعية: Male, Heart Rate, Respiration, Imidazoles, Animals, Hypnotics and Sedatives, Blood Pressure, Electroencephalography, Medetomidine, Rats, Wistar, Adrenergic alpha-Agonists, Rats
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::361af9e7727cc70f06fc0bf1e467a000
https://pubmed.ncbi.nlm.nih.gov/9399976