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1دورية أكاديمية
المؤلفون: J. Hundt, J. Buschmann
المصدر: Materiales de Construccion, Vol 23, Iss 149, Pp 121-122 (1973)
مصطلحات موضوعية: Materials of engineering and construction. Mechanics of materials, TA401-492
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: SC Hess, WJ Stark, D Mohn, N Cohrs, S Märsmann, M Calcagni, P Cinelli, J Buschmann
المصدر: European Cells & Materials, Vol 34, Pp 232-248 (2017)
مصطلحات موضوعية: PLGA, amorphous calcium phosphate, apatite, nanoparticle, adipose-derived stem cell, composite, PCR, stem cells, differentiation, Diseases of the musculoskeletal system, RC925-935, Orthopedic surgery, RD701-811
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: O Evrova, J Buschmann
المصدر: European Cells & Materials, Vol 34, Pp 15-39 (2017)
مصطلحات موضوعية: the range of bioactive components in dentine and specific biological effects on bone-derived mesenchymal stem cells (MSCs) in humans are less well understood. The aims of this study were to further elucidate the biological response of MSCs to demineralised dentine matrix (DDM) in enhancing wound repair responses and ascertain key contributing components. Dentine was obtained from human teeth and DDM proteins solubilised with ethylenediaminetetraacetic acid (EDTA). Bone marrow derived MSCs were commercially obtained. Cells with a more immature phenotype were then selected by preferential fibronectin adhesion (FN-BMMSCs) for use in subsequent in vitro assays. DDM at 10 µg/mL reduced cell expansion, attenuated apoptosis and was the minimal concentration capable of inducing osteoblastic differentiation. Enzyme-linked immunosorbent assay (ELISA) quantification of growth factors indicated physiological levels produced the above responses, transforming growth factor β (TGF-β1) was predominant (15.6 ng/mg DDM), with relatively lower concentrations of BMP-2, FGF, VEGF and PDGF (6.2-4.7 ng/mg DDM). Fractionation of growth factors from other DDM components by heparin affinity chromatography diminished osteogenic responses. Depletion of biglycan from DDM also attenuated osteogenic potency, which was partially rescued by the isolated biglycan. Decorin depletion from DDM had no influence on osteogenic potency. Collectively, these results demonstrate the potential of DDM for the delivery of physiological levels of growth factors for bone repair processes, Mesenchymal stem cells, dentine, growth factors, biglycan, decorin, cell expansion, osteoblast differentiation, migration, apoptosis, Surgery, RD1-811, Diseases of the musculoskeletal system, RC925-935
وصف الملف: electronic resource
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4دورية أكاديمية
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5دورية أكاديمية
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6دورية أكاديمية
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7دورية أكاديمية
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8دورية أكاديمية
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9
المؤلفون: A.M. Api, D. Belsito, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.A. Cancellieri, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, A.D. Fryer, L. Jones, K. Joshi, M. Kumar, A. Lapczynski, M. Lavelle, I. Lee, D.C. Liebler, H. Moustakas, M. Na, T.M. Penning, G. Ritacco, J. Romine, N. Sadekar, T.W. Schultz, D. Selechnik, F. Siddiqi, I.G. Sipes, G. Sullivan, Y. Thakkar, Y. Tokura
المساهمون: Publica
المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USPمصطلحات موضوعية: Micronucleus Tests, Phenyl Ethers, Reproduction, Skin Absorption, TOXICOLOGIA AMBIENTAL, General Medicine, Toxicology, Perfume, Toxicity Tests, Animals, Humans, Cells, Cultured, Databases, Chemical, Skin Tests, Food Science
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af8359f846afc164cbf5ae84da550cd
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10
المؤلفون: A.M. Api, D. Belsito, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.A. Cancellieri, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, A.D. Fryer, L. Jones, K. Joshi, M. Kumar, A. Lapczynski, M. Lavelle, I. Lee, D.C. Liebler, H. Moustakas, M. Na, T.M. Penning, G. Ritacco, J. Romine, N. Sadekar, T.W. Schultz, D. Selechnik, F. Siddiqi, I.G. Sipes, G. Sullivan, Y. Thakkar, Y. Tokura
المساهمون: Publica
المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USPمصطلحات موضوعية: Odorants, TOXICOLOGIA AMBIENTAL, Cyclohexane Monoterpenes, Registries, General Medicine, Toxicology, Perfume, Food Science
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9425174552641f7a8df155beec080d9
https://publica.fraunhofer.de/handle/publica/439627