المؤلفون: Rong Jin, Min Wang, Wei Zhong, Charles R. Kissinger, J. Ernest Villafranca, Guohong Li

المصدر: Frontiers in Neurology, Vol 13 (2022)

مصطلحات موضوعية: ischemic stroke, J147, tPA, hemorrhage, cerebroprotection, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2022.821082/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/b67bb812dc3143ec975ffd388d15fc3c

المؤلفون: Babine Robert E, Bruce G Gold, J Ernest Villafranca

المصدر: Expert Opinion on Therapeutic Patents. 15:555-573

مصطلحات موضوعية: Pharmacology, FKBP, Immunophilins, Drug Discovery, Patent literature, biology.protein, General Medicine, Biology, DNA-binding protein, Subclass, Tacrolimus, Neurotrophin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f4d7cc3a76169972b67c311c39dc6abf
https://doi.org/10.1517/13543776.15.5.555

المؤلفون: Michele Ann Mctigue, Michael R Gehring, Chris Pinko, J. Ernest Villafranca, Chen-Chen Kan, Camran V Parast, Krzysztof Appelt, Richard E. Showalter, Barbara Mroczkowski, John A Wickersham, Anna Tempczyk-Russell

المصدر: Structure. 7:319-330

مصطلحات موضوعية: Models, Molecular, Protein Folding, Protein Conformation, Recombinant Fusion Proteins, Molecular Sequence Data, Neovascularization, Physiologic, Mitogen-activated protein kinase kinase, Crystallography, X-Ray, Protein Structure, Secondary, Receptor tyrosine kinase, Substrate Specificity, MAP2K7, angiogenesis, Structure-Activity Relationship, kinase insert domain, Adenosine Triphosphate, Structural Biology, Catalytic Domain, Humans, Receptors, Growth Factor, ASK1, Amino Acid Sequence, Kinase activity, Growth Substances, Molecular Biology, Binding Sites, Sequence Homology, Amino Acid, biology, MAP kinase kinase kinase, tyrosine kinase, Receptor Protein-Tyrosine Kinases, Protein-Tyrosine Kinases, Peptide Fragments, Cell biology, Kinetics, Receptors, Vascular Endothelial Growth Factor, Biochemistry, Multigene Family, Mutagenesis, Site-Directed, biology.protein, Cyclin-dependent kinase 9, X-ray structure, Sequence Alignment, signal transduction, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cd0c114d6524dab68f410cf59cf22b
https://doi.org/10.1016/s0969-2126(99)80042-2

المؤلفون: L. A. K. Pelletier, John H. Tatlock, Xinjun J. Hou, Richard E. Showalter, M. Angelica Linton, J. Ernest Villafranca, Charles R. Kissinger, Anna Tempczyk

المصدر: Bioorganic & Medicinal Chemistry Letters. 7:1007-1012

مصطلحات موضوعية: chemistry.chemical_classification, Phosphoric monoester hydrolases, Molecular model, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Combinatorial chemistry, Small molecule, In vitro, Calcineurin, Enzyme, Drug Discovery, Molecular Medicine, Endothall, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::56059b2c7decb22fe37b673720f9d274
https://doi.org/10.1016/s0960-894x(97)00141-8

المؤلفون: Susumo Katoh, J. Ernest Villafranca, Cristina T. Lewis, Michael Imbacuan, Richard E. Showalter, Babine Robert E, Littlefield Ethel S, Judy V. French, Hans E. Parge, Ted M. Bleckman, John H. Tatlock, L. A. K. Pelletier

المصدر: Bioorganic & Medicinal Chemistry Letters. 6:385-390

مصطلحات موضوعية: Crystallography, FKBP, Design synthesis, Chemistry, Organic Chemistry, Clinical Biochemistry, Drug Discovery, X-ray, Pharmaceutical Science, Molecular Medicine, Crystal structure, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d40c1f82d7ab92eaa7836f31e40e88c9
https://doi.org/10.1016/0960-894x(96)00032-7

المؤلفون: J. V. French, Richard E. Showalter, Hans E. Parge, Vincent J. Kalish, Daniel R. Knighton, John H. Tatlock, Christina T. Lewis, J. Ernest Villafranca

المصدر: Bioorganic & Medicinal Chemistry Letters. 5:2489-2494

مصطلحات موضوعية: Carvone, Rotamase activity, Stereochemistry, Effector, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Small molecule, chemistry.chemical_compound, FKBP, Pyranose, chemistry, Drug Discovery, Domain (ring theory), Molecular Medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::21ce686745ca70ec16a529ff6519260e
https://doi.org/10.1016/0960-894x(95)00429-w

المؤلفون: C. T. Lewis, Babine Robert E, Charles R. Kissinger, Ted M. Bleckman, Richard E. Showalter, J. Ernest Villafranca, Kathleen D. Tucker, L. A. K. Pelletier, Hans E. Parge, Ellen W. Moomaw

المصدر: Bioorganic & Medicinal Chemistry Letters. 5:1719-1724

مصطلحات موضوعية: Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, X-ray, Pharmaceutical Science, Crystal structure, Biochemistry, Crystallography, FKBP, Design synthesis, Drug Discovery, Molecular Medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e618be6998fefcd8472870a7767fd495
https://doi.org/10.1016/0960-894x(95)00290-a

المؤلفون: J. Ernest Villafranca, Paul J Gomes, Elliott C. Lasser, S. David Miller, Erik Viirre

المصدر: Journal of Allergy and Clinical Immunology. 137:AB262

مصطلحات موضوعية: 0301 basic medicine, 060102 archaeology, business.industry, media_common.quotation_subject, Immunology, 06 humanities and the arts, 03 medical and health sciences, 030104 developmental biology, Immunology and Allergy, Medicine, Contrast (vision), 0601 history and archaeology, business, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9f81e0a1b490cb7ab2c69554b2fc6ddb
https://doi.org/10.1016/j.jaci.2015.12.995

المؤلفون: Jürgen Götz, Amandine Grimm, Anne Eckert, Lars M. Ittner, Yun An Lim, J. Ernest Villafranca, Ayikoe Guy Mensah-Nyagan, Maria Giese

المصدر: PLoS ONE, Vol 6, Iss 12, p e28887 (2011)
PLoS ONE

مصطلحات موضوعية: Aucun, drug effects, enzymology, Amylin, Neural Homeostasis, Mitochondrion, medicine.disease_cause, Biochemistry, Oxidative Phosphorylation, Neurobiology of Disease and Regeneration, Enzyme Inhibitors, chemistry.chemical_classification, Multidisciplinary, Estradiol, chemistry, pharmacology, 3-Hydroxyacyl CoA Dehydrogenases, Neurochemistry, Cytoprotection, Islet Amyloid Polypeptide, Mitochondria, Enzymes, Neurology, Toxicity, Medicine, Protein Binding, Research Article, Biotechnology, medicine.medical_specialty, metabolism, toxicity, Cell Survival, Science, Cell Respiration, Down-Regulation, Oxidative phosphorylation, Biology, Cell Line, Enzyme Regulation, Oxygen Consumption, Alzheimer Disease, Internal medicine, medicine, Humans, MTT assay, Enzyme Kinetics, Reactive oxygen species, Amyloid beta-Peptides, Peptide Fragments, Metabolism, Endocrinology, Small Molecules, Dementia, Molecular Neuroscience, Reactive Oxygen Species, Oxidative stress, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91d8e233791c7c0be8469971ab13158
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174920/pdf/?tool=EBI

المؤلفون: James Arthur Thomson, Richard E. Showalter, J. Ernest Villafranca, Anna Tempczyk-Russell, Melwyn A. Abreo, Laura A. Pelletier, Charles R. Kissinger, Bin Li, Jerry J. Meng, Stephen Margosiak, Charles S. Agree, Robert M. Aust, Darin Vanderpool, Paul A. Rejto

المصدر: Journal of molecular biology. 342(3)

مصطلحات موضوعية: Models, Molecular, DNA, Complementary, Stereochemistry, Protein Conformation, Molecular Sequence Data, Dehydrogenase, In Vitro Techniques, Crystallography, X-Ray, Cofactor, HSD17B10, Structural Biology, Oxidoreductase, Alzheimer Disease, Catalytic Domain, Humans, Amino Acid Sequence, Enzyme Inhibitors, Protein Structure, Quaternary, Molecular Biology, Alcohol dehydrogenase, chemistry.chemical_classification, Short-chain dehydrogenase, Amyloid beta-Peptides, biology, Base Sequence, Sequence Homology, Amino Acid, 3-Hydroxyacyl CoA Dehydrogenases, NAD, 3-Hydroxyacyl-CoA Dehydrogenase, Recombinant Proteins, Kinetics, Biochemistry, chemistry, Drug Design, biology.protein, Mutagenesis, Site-Directed, NAD+ kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe97b9ef9d0d7ebbc6bae3700cb65d22
https://pubmed.ncbi.nlm.nih.gov/15342248