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1دورية أكاديمية
المؤلفون: Nicola Melillo, Daniel Scotcher, J. Gerry Kenna, Claudia Green, Catherine D. G. Hines, Iina Laitinen, Paul D. Hockings, Kayode Ogungbenro, Ebony R. Gunwhy, Steven Sourbron, John C. Waterton, Gunnar Schuetz, Aleksandra Galetin
المصدر: Pharmaceutics, Vol 15, Iss 3, p 896 (2023)
مصطلحات موضوعية: gadoxetate, pharmacokinetics, hepatic transporters, modelling and simulation, DCE-MRI, OATP1B, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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المؤلفون: J. Gerry Kenna, Jack Uetrecht
المصدر: Drug Metabolism and Disposition. 46:1658-1669
مصطلحات موضوعية: Risk, 0301 basic medicine, Drug, Idiosyncratic drug reaction, media_common.quotation_subject, Pharmaceutical Science, Pharmacology, Immune tolerance, 03 medical and health sciences, Immune system, Drug Discovery, medicine, Animals, Humans, Cytotoxicity, media_common, Liver injury, Drug discovery, Chemistry, In vitro toxicology, medicine.disease, 030104 developmental biology, Liver, Hepatocytes, Biological Assay, Chemical and Drug Induced Liver Injury
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3142799f848ce710abc09598107c48
https://doi.org/10.1124/dmd.118.082719 -
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المؤلفون: J Gerry Kenna
المصدر: Expert Opinion on Drug Metabolism & Toxicology. 13:567-574
مصطلحات موضوعية: 0301 basic medicine, Drug, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Endpoint Determination, media_common.quotation_subject, Pharmacology, Toxicology, 03 medical and health sciences, Species Specificity, In vivo, Human biology, Toxicity Tests, medicine, Animals, Humans, Intensive care medicine, media_common, Cardiotoxicity, Toxicity data, business.industry, In vitro toxicology, General Medicine, Clinical trial, 030104 developmental biology, Drug Design, Toxicity, Chemical and Drug Induced Liver Injury, business
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المؤلفون: J Gerry Kenna, Rebecca Ram
مصطلحات موضوعية: Cardiotoxicity, business.industry, Drug discovery, Toxicity, Medicine, Drug reaction, business, Bioinformatics, medicine.disease_cause, Genotoxicity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fc08e453e5d790290f4386a4a2d3305e
https://doi.org/10.1016/b978-0-12-813697-3.00020-2 -
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المؤلفون: Katya Tsaioun, J. Gerry Kenna, Kathy Archibald, Pandora Pound
المصدر: J R Soc Med
مصطلحات موضوعية: 0301 basic medicine, Organizational innovation, Knowledge management, Letter, Drug Industry, business.industry, MEDLINE, General Medicine, Organizational Innovation, United Kingdom, United States, Interviews as Topic, 03 medical and health sciences, 030104 developmental biology, SAFER, Drug Discovery, Microchip Analytical Procedures, Medicine, Humans, Safety, business, Drug industry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d13e8b9c33f46c29465fbf89267d0f
https://pubmed.ncbi.nlm.nih.gov/31074338 -
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المؤلفون: J. Gerry Kenna, Elizabeth Baker, Lorna Ewart, J. Lowry Curley, Jane M. Gunther, Bruce A. Donzanti, Helene D. Clayton-Jeter, Michael N. Liebman, Catherine L. Pugh, Paul B. Watkins, Kristie Sullivan, Nancy Beck, Edward L. LeCluyse, Ellen L. Berg, P. Charukeshi Chandrasekera
المصدر: Drug discovery today. 24(2)
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Knowledge management, business.industry, In silico, MEDLINE, Drug Evaluation, Preclinical, Animal Testing Alternatives, 03 medical and health sciences, Patient safety, 030104 developmental biology, 0302 clinical medicine, Drug development, Inventions, 030220 oncology & carcinogenesis, Animal Testing Alternative, Drug Discovery, Medicine, Humans, Patient Safety, business
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المؤلفون: Joseph W. Polli, Jonathan Maher, Kunal S Taskar, A. David Rodrigues, Christoph Funk, Michael J. Hafey, Robert W. Yucha, Kim L. R. Brouwer, Y. Anne Pak, Paul B. Watkins, David Dai, Jenny M. Pedersen, David L. Bourdet, Kyunghee Yang, Christina Battista, J. Gerry Kenna, Yurong Lai, Kenneth R. Brouwer
المصدر: Clinical Pharmacology and Therapeutics
مصطلحات موضوعية: 0301 basic medicine, Drug, Protein Conformation, media_common.quotation_subject, Reviews, Pharmacology, In Vitro Techniques, Models, Biological, Risk Assessment, 03 medical and health sciences, Structure-Activity Relationship, Drug Development, In vivo, Risk Factors, Membrane Transport Modulators, Drug Discovery, medicine, Animals, Bile, Humans, Pharmacology (medical), Computer Simulation, ATP Binding Cassette Transporter, Subfamily B, Member 11, Cells, Cultured, media_common, Liver injury, Mechanism (biology), Drug discovery, business.industry, In vitro toxicology, medicine.disease, Bile Salt Export Pump, 3. Good health, 030104 developmental biology, Liver, Drug Design, Computer-Aided Design, Chemical and Drug Induced Liver Injury, Risk assessment, business
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المؤلفون: Michael D. Aleo, Deborah S. Light, J. Gerry Kenna
المصدر: Methods in Pharmacology and Toxicology ISBN: 9781493976768
مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, business.industry, 030220 oncology & carcinogenesis, Toxicity, Medicine, Computational biology, business, Interpretation (model theory)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e53444d49968ffdd18e7146aa0ce0d44
https://doi.org/10.1007/978-1-4939-7677-5_17 -
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المؤلفون: Andreas Baudy, Manishkumar Patel, Paul D. Hockings, Daniel Scotcher, John C. Waterton, Aleksandra Galetin, J. Gerry Kenna, Gunnar Schuetz, Steven Sourbron, Catherine D. G. Hines, Sabina Ziemian
المصدر: Drug-Induced Liver Toxicity
Methods in Pharmacology and Toxicology ISBN: 9781493976768
Kenna, J G, Waterton, J C, Baudy, A, Galetin, A, Hines, C D G, Hockings, P, Patel, M, Scotcher, D, Sourbron, S, Ziemian, S & Schuetz, G 2018, Noninvasive preclinical and clinical imaging of liver transporter function relevant to drug-induced liver injury . in Drug-Induced Liver Toxicity . Methods in Pharmacology and Toxicology, no. 9781493976768, Humana Press, Inc, New York, NY, pp. 627-651 . https://doi.org/10.1007/978-1-4939-7677-5_30
Methods in Pharmacology and Toxicology
Methods in Pharmacology and Toxicology-Drug-Induced Liver Toxicityمصطلحات موضوعية: Drug, Drug-induced liver injury, Gadoxetate, media_common.quotation_subject, Hepatobiliary transporters, Causality assessment, Pharmacology, 030226 pharmacology & pharmacy, 030218 nuclear medicine & medical imaging, Drug labelling, Pharmacology, Toxicology and Pharmaceutics(all), 03 medical and health sciences, 0302 clinical medicine, Medicine, Drug-drug interactions, Pharmacology (medical), Clinical imaging, media_common, Liver injury, business.industry, Hepatotoxicity, Transporter, medicine.disease, Bile Salt Export Pump, 3. Good health, Molecular Medicine, Bile salt export pump, business, Function (biology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9d95eadbc9aaa8385974439dd215e6
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المؤلفون: Huw B. Jones, Ian D. Wilson, Alison J. Foster, James A. Akingbasote, J. Gerry Kenna, Rhiannon David, Nigel J. Gooderham
مصطلحات موضوعية: 0301 basic medicine, Liver injury, chemistry.chemical_classification, medicine.medical_specialty, Necrosis, Health, Toxicology and Mutagenesis, Glutamate dehydrogenase, Inflammation, Pharmacology, Reductase, Biology, Toxicology, medicine.disease, In vitro, 03 medical and health sciences, Chemistry, 030104 developmental biology, Endocrinology, Enzyme, chemistry, Internal medicine, medicine, Alkaline phosphatase, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad67f203607eb0b677879b19d0a847b
https://europepmc.org/articles/PMC6062145/