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المؤلفون: Carol Addy, Ashley Martucci, Marleen Depré, J. N. de Hoon, Joanna Z. Peng, John A. Wagner, Amy O. Johnson-Levonas, I.N. Gendrano, Rajesh Krishna, S. Aubrey Stoch, Wouter Haazen, Martine Robberechts, Xiaoli S. Glasgow, Daniel Tatosian
المصدر: Journal of Clinical Pharmacology
مصطلحات موضوعية: Adult, Male, DPP-4 activity, type 2 diabetes mellitus, Pharmacokinetics/Pharmacodynamics, Cmax, DPP‐4 activity, Pharmacology, Omarigliptin, Heterocyclic Compounds, 2-Ring, 030226 pharmacology & pharmacy, QT interval, Drug Administration Schedule, once‐weekly, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Pharmacokinetics, omarigliptin, Humans, Medicine, Pharmacology (medical), Dipeptidyl peptidase-4, Pyrans, Dipeptidyl-Peptidase IV Inhibitors, Dose-Response Relationship, Drug, business.industry, once-weekly, Area under the curve, Middle Aged, Healthy Volunteers, Postprandial, 030220 oncology & carcinogenesis, Pharmacodynamics, business, pharmacokinetics
وصف الملف: Print-Electronic; application/msword
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المؤلفون: Sandra M. Sanabria-Bohórquez, J. N. de Hoon, K. Van Laere, Richard Hargreaves, Raymond E. Gibson, Spencer J. Tye, Leslie J. Street, Ruth M. McKernan, I De Lepeleire, Robert W. Carling, Keith A. Wafford, Andrew Pike, John R. Atack, Guy Bormans, Christine Ryan, David James Hallett, HD Burns, M. G Murphy, Wai-Si Eng, A. Van Hecken, G. R. Dawson
المصدر: Journal of Psychopharmacology. 25:329-344
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Elevated plus maze, Time Factors, Adolescent, Hydrocarbons, Fluorinated, medicine.drug_class, Population, Anxiety, Pharmacology, Heterocyclic Compounds, 4 or More Rings, Anxiolytic, Partial agonist, Rats, Sprague-Dawley, Mice, Young Adult, Species Specificity, Internal medicine, Animals, Humans, Medicine, Pharmacology (medical), GABA-A Receptor Agonists, education, Saimiri, education.field_of_study, Benzodiazepine, Dose-Response Relationship, Drug, business.industry, GABAA receptor, Antagonist, Middle Aged, Receptors, GABA-A, Rats, Disease Models, Animal, Protein Subunits, Psychiatry and Mental health, Endocrinology, Anti-Anxiety Agents, Flumazenil, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea0a5ae22a6d2851dd26b1e9a8bbbb4
https://doi.org/10.1177/0269881109354928 -
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المؤلفون: J. N. de Hoon, Guy Bormans, John R. Atack, M. G Murphy, Sandra M. Sanabria-Bohórquez, I De Lepeleire, A. Van Hecken, Keith A. Wafford, G. R. Dawson, K. Van Laere, Richard Hargreaves, Leslie J. Street, Ruth M. McKernan, Spencer J. Tye, HD Burns
المصدر: Journal of Psychopharmacology. 25:314-328
مصطلحات موضوعية: Adult, Male, Agonist, medicine.medical_specialty, Adolescent, Hydrocarbons, Fluorinated, medicine.drug_class, Sedation, Drug Evaluation, Preclinical, Anxiety, Pharmacology, Heterocyclic Compounds, 4 or More Rings, Anxiolytic, Partial agonist, Chlordiazepoxide, Rats, Sprague-Dawley, Mice, Young Adult, Species Specificity, Internal medicine, medicine, Animals, Humans, Tissue Distribution, Pharmacology (medical), GABA-A Receptor Agonists, Saimiri, Benzodiazepine, Binding Sites, Dose-Response Relationship, Drug, Chemistry, GABAA receptor, Brain, Middle Aged, Rats, Disease Models, Animal, Protein Subunits, Psychiatry and Mental health, Endocrinology, Anti-Anxiety Agents, Flumazenil, Positron-Emission Tomography, medicine.symptom, Protein Binding, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e190b386986f0d8f06dedccdb3ce130
https://doi.org/10.1177/0269881109354927 -
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المؤلفون: Eseng Lai, T Laethem, J. N. de Hoon, Tami Crumley, M. Oeyen, I De Lepeleire, C. Thach, A. Van Hecken, Marleen Depré, Larissa Wenning, Kathryn E. Mazina, P. Clement, Keith Gottesdiener, Paul J. Deutsch, J. Van Effen
المصدر: European Journal of Clinical Pharmacology. 63:135-141
مصطلحات موضوعية: Adult, Male, Indoles, medicine.drug_class, Receptors, Prostaglandin, Administration, Oral, Prostaglandin, Mucous membrane of nose, Nasal congestion, chemistry.chemical_compound, Double-Blind Method, otorhinolaryngologic diseases, Humans, Medicine, Pharmacology (medical), Receptors, Immunologic, Pharmacology, Cross-Over Studies, Dose-Response Relationship, Drug, integumentary system, medicine.diagnostic_test, Prostaglandin D2, business.industry, Rhinitis, Allergic, Seasonal, General Medicine, respiratory system, Prostaglandin antagonist, Receptor antagonist, Rhinomanometry, chemistry, Immunology, Female, lipids (amino acids, peptides, and proteins), Nasal administration, Nasal Obstruction, medicine.symptom, business
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المؤلفون: A. Dynder, J. N. de Hoon, M. L. Juliano, Kevin J. Petty, Marleen Depré, Jozef Arnout, Keith Gottesdiener, L. Wildonger, I De Lepeleire, A. Van Hecken
المصدر: Alimentary Pharmacology & Therapeutics. 16:1683-1688
مصطلحات موضوعية: Aspirin, medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, Pharmacology, Placebo, Enteric coating, Surgery, Thromboxane B2, chemistry.chemical_compound, chemistry, Oral administration, medicine, Platelet aggregation inhibitor, Pharmacology (medical), Platelet, Arachidonic acid, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb7be2a8778c3747f1687e40d9493663
https://doi.org/10.1046/j .1365-2036.2002.01332.x -
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المؤلفون: R. Peck, N. Dallow, F. H. Vanmolkot, P. Williams, J. Mccolm, J. N. De Hoon, P. Barrington
المصدر: European Journal of Clinical Pharmacology. 58:303-308
مصطلحات موضوعية: Adult, Male, Agonist, medicine.medical_specialty, medicine.drug_class, Diastole, Blood Pressure, Placebo, Sensitivity and Specificity, Veins, Double-Blind Method, Internal medicine, medicine, Humans, Pharmacology (medical), Vein, Pharmacology, Cross-Over Studies, Dose-Response Relationship, Drug, Sumatriptan, business.industry, General Medicine, Toes, Hand, Crossover study, Serotonin Receptor Agonists, Peripheral, medicine.anatomical_structure, Blood pressure, Receptor, Serotonin, 5-HT1D, Receptors, Serotonin, Anesthesia, Arm, Receptor, Serotonin, 5-HT1B, Cardiology, business, medicine.drug
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المؤلفون: C. Macleod, J. N. de Hoon, Deborah Panebianco, Tae H. Han, Chodakewitz Jeffrey A, I. De Lepeleire, M. G Murphy, Martin O. Behm, William B. Smith, John Palcza, Rebecca L. Blanchard, Marleen Depré
المصدر: Cephalalgia : an international journal of headache. 33(16)
مصطلحات موضوعية: Adult, Male, Mean arterial pressure, Migraine Disorders, Hemodynamics, Blood Pressure, Placebo, Young Adult, Double-Blind Method, Calcitonin Gene-Related Peptide Receptor Antagonists, medicine, Humans, Drug Interactions, Analgesics, Telcagepant, Cross-Over Studies, business.industry, Sumatriptan, Imidazoles, General Medicine, Azepines, Middle Aged, medicine.disease, Crossover study, Blood pressure, Migraine, Anesthesia, cardiovascular system, Female, Neurology (clinical), business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e46433a3056c8d8d2db138b8e00cfb
https://pubmed.ncbi.nlm.nih.gov/23798725 -
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المؤلفون: J. N. de Hoon, F. Guillard, Floris H.M. Vanmolkot, James A. Palmer, A. Van Hecken, B. Van der Schueren, Marleen Depré, Martin W. Lunnon, Bart Laurijssens
المصدر: Journal of clinical pharmacology. 49(3)
مصطلحات موضوعية: Adult, Male, Migraine Disorders, Nitric Oxide Synthase Type II, Absorption (skin), Pharmacology, Nitric Oxide, Nitric oxide, chemistry.chemical_compound, Pharmacokinetics, Medicine, Humans, Pharmacology (medical), Sulfones, Nitrates, business.industry, Half-life, medicine.disease, Confidence interval, chemistry, Migraine, Pharmacodynamics, Area Under Curve, Exhaled nitric oxide, Tyrosine, Female, business, Half-Life
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المؤلفون: Floris H.M. Vanmolkot, J. N. de Hoon, B. Van der Schueren, I. De Lepeleire, A. Rogiers, Stefanie A. Kane, A. Van Hecken, M Depre, S.R. Sinclair
المصدر: The Journal of pharmacology and experimental therapeutics. 325(1)
مصطلحات موضوعية: Adult, medicine.medical_specialty, Adolescent, Calcitonin Gene-Related Peptide, Vasodilation, Human skin, Calcitonin gene-related peptide, Nitric oxide, chemistry.chemical_compound, Forearm, In vivo, Internal medicine, Laser-Doppler Flowmetry, Medicine, Humans, Pharmacokinetics, Single-Blind Method, Skin, Pharmacology, Cross-Over Studies, integumentary system, business.industry, Middle Aged, Peptide Fragments, Endocrinology, medicine.anatomical_structure, chemistry, Calcitonin, Capsaicin, Regional Blood Flow, Molecular Medicine, business, Drug Antagonism, Receptors, Calcitonin Gene-Related Peptide
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8dec47d7cb4a55283c54e9af9a1e4b3
https://pubmed.ncbi.nlm.nih.gov/18216286 -
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المؤلفون: D Hilliard, I De Lepeleire, J. N. de Hoon, KG Gottesdiener, Fang Liu, A. Van Hecken, Marleen Depré, JA Wagner, Larissa Wenning, E Lai, Gary P. O'Neill, Howard E. Greenberg, Kathleen M. Metters, TM Crumley
المصدر: Clinical pharmacology and therapeutics. 83(6)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Indoles, Thromboxane, Receptors, Prostaglandin, Prostaglandin, Pharmacology, chemistry.chemical_compound, Pharmacokinetics, Double-Blind Method, Oral administration, Internal medicine, Medicine, Humans, Pharmacology (medical), Receptors, Immunologic, Prostaglandin D2 receptor, Dose-Response Relationship, Drug, business.industry, Antagonist, Headache, Middle Aged, Endocrinology, chemistry, Pharmacodynamics, business, Laropiprant