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المؤلفون: Guadalupe Garcia-Tsao, Jaime Bosch, Zeid Kayali, Stephen A. Harrison, Manal F. Abdelmalek, Eric Lawitz, Sanjaya K. Satapathy, Marwan Ghabril, Mitchell L. Shiffman, Ziad H. Younes, Paul J. Thuluvath, Annalisa Berzigotti, Agustin Albillos, James M. Robinson, David T. Hagerty, Jean L. Chan, Arun J. Sanyal, M. Abdelmalek, K. Bhamidimarri, B. Borg, S. Caldwell, J. Fenkel, B. Freilich, M. Fuchs, M. Ghabril, R. Ghalib, S. Gonzalez, S. Gordon, B. Hameed, S. Harrison, Z. Kayali, N. Kemmer, K. Korenblat, M. Lai, C. Landis, E. Lawitz, W. Lee, S. Lidofsky, E. Mena, M. Noureddin, A. Paredes, N. Pyrsopoulos, R. Reddy, M. Rinella, D. Rockey, M. Rodriguez, M. Ryan, S. Sarkar, S. Satapathy, A. Scanga, M. Shiffman, M. Siddiqui, D. Simonetto, W. Syn, P. Thuluvath, R. Vemulapalli, J. Vierling, Z. Younes, A. Albillos, J. Arenas Ruiz-Tapiador, S. Augustin, J. Calleja, J. Crespo Garcia, L. Garcia Buey, J.C. Garcia-Pagan, C. Villanueva, C. Bureau, N. Carbonell, V. Leroy, P.-E. Rautou, H. Heinzow, I. Schiefke, A. Zipprich, A. Berzigotti, B. Muellhaupt
المصدر: Garcia-Tsao, Guadalupe; Bosch, Jaime; Kayali, Zeid; Harrison, Stephen A; Abdelmalek, Manal F; Lawitz, Eric; Satapathy, Sanjaya K; Ghabril, Marwan; Shiffman, Mitchell L; Younes, Ziad H; Thuluvath, Paul J; Berzigotti, Annalisa; Albillos, Agustin; Robinson, James M; Hagerty, David T; Chan, Jean L; Sanyal, Arun J (2020). Randomized Placebo-Controlled Trial of Emricasan in Non-alcoholic Steatohepatitis (NASH) Cirrhosis with Severe Portal Hypertension. Journal of hepatology, 72(5), pp. 885-895. Elsevier 10.1016/j.jhep.2019.12.010 <http://dx.doi.org/10.1016/j.jhep.2019.12.010>
مصطلحات موضوعية: Liver Cirrhosis, Male, 0301 basic medicine, medicine.medical_specialty, Cirrhosis, Portal venous pressure, Placebo-controlled study, Administration, Oral, 610 Medicine & health, Placebo, Severity of Illness Index, Gastroenterology, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Double-Blind Method, Non-alcoholic Fatty Liver Disease, Internal medicine, Hypertension, Portal, Clinical endpoint, Humans, Medicine, Prospective Studies, Pentanoic Acids, Aged, Hepatology, business.industry, Middle Aged, medicine.disease, Caspase Inhibitors, Portal Pressure, Treatment Outcome, 030104 developmental biology, Portal hypertension, Female, 030211 gastroenterology & hepatology, Steatohepatitis, business, Biomarkers, Follow-Up Studies
وصف الملف: application/pdf
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2دورية أكاديمية
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المؤلفون: J. White, P. Lopez, Arun J. Sanyal, S. Lamle, J. Vierling, M. Yoneda, D. Lazas, G. Neff, E.J. Lawitz, W. Kim, S. Augustin, S. Hsia, G.G. Boon Bee, A. Sheikh, J. Frias, D. Aizenberg, F. Schaefer, K.J. Lucas, Y. Eguchi, Y. Loeffler, M. Martic, C. Brass
المصدر: Digestive and Liver Disease. 52:e38
مصطلحات موضوعية: Agonist, Hepatology, medicine.drug_class, business.industry, Gastroenterology, medicine, Dose dependence, In patient, Pharmacology, Alanine aminotransferase, business
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المؤلفون: Wayne F. Anderson, Ryan J. Vierling, J M Smith, Caren L. Freel Meyers, Andrew T. Koppisch, Misty L. Kuhn, Nicole V. Warrington
المصدر: The Journal of antibiotics
مصطلحات موضوعية: Antiparasitic, medicine.drug_class, DXP synthase, Organophosphonates, medicine.disease_cause, Gram-Positive Bacteria, 01 natural sciences, Article, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, isoprenoid biosynthesis, Biosynthesis, Transferases, Drug Discovery, Drug Resistance, Bacterial, Gram-Negative Bacteria, medicine, Humans, Molecular Targeted Therapy, Enzyme Inhibitors, Escherichia coli, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, ATP synthase, biology, 010405 organic chemistry, Drug Synergism, Antimicrobial, biology.organism_classification, thiamin diphosphate, 3. Good health, 0104 chemical sciences, Anti-Bacterial Agents, Enzyme, chemistry, Biochemistry, selective inhibitor, Salmonella enterica, biology.protein
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5دورية أكاديمية
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المصدر: ChemBioChem. 14:1309-1315
مصطلحات موضوعية: Nitrogen, Stereochemistry, Biochemistry, Article, Substrate Specificity, chemistry.chemical_compound, Biosynthesis, Transferases, Catalytic Domain, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, ATP synthase, biology, Terpenes, Organic Chemistry, Mutagenesis, Active site, Nitroso, Pyruvate dehydrogenase complex, Carbon, Kinetics, Enzyme, chemistry, Biocatalysis, biology.protein, Molecular Medicine, DXP synthase
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7دورية أكاديمية
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المؤلفون: Ryan J. Vierling, J M Smith, Caren L. Freel Meyers
المصدر: Med. Chem. Commun.. 3:65-67
مصطلحات موضوعية: Pharmacology, biology, ATP synthase, Chemistry, organic chemicals, Organic Chemistry, Pharmaceutical Science, Selective inhibition, Bioinformatics, Biochemistry, Article, Isoprenoid biosynthesis, Transformation (genetics), Drug Discovery, biology.protein, Molecular Medicine, DXP synthase, Pathogen, 1-deoxy-D-xylulose-5-phosphate synthase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ce9dbaa3a7e139da2f0f0e404d4ee5
https://doi.org/10.1039/c1md00233c -
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المؤلفون: Marlon L. Walker, Amit Vaish, David J. Vanderah, D. Travis Gallagher, Fay Crawshaw, Ryan J. Vierling
المصدر: Colloids and surfaces. B, Biointerfaces. 122
مصطلحات موضوعية: Ethylene Oxide, Low protein, Stereochemistry, Chemistry, Surface Properties, Substrate (chemistry), Membrane Proteins, Self-assembled monolayer, Surfaces and Interfaces, General Medicine, Polymerization, Crystallography, Colloid and Surface Chemistry, Adsorption, Membrane, Monolayer, Physical and Theoretical Chemistry, Integral membrane protein, Biotechnology, Protein adsorption
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المؤلفون: David J. Vanderah, Ryan J. Vierling, Marlon L. Walker
المصدر: Langmuir : the ACS journal of surfaces and colloids. 25(9)
مصطلحات موضوعية: Ethylene Oxide, Stereochemistry, Infrared spectroscopy, Substrate Specificity, chemistry.chemical_compound, Adsorption, Monolayer, Electrochemistry, Molecule, Animals, General Materials Science, Spectroscopy, Ethylene oxide, Molecular Structure, Spectrum Analysis, Fibrinogen, Self-assembled monolayer, Serum Albumin, Bovine, Surfaces and Interfaces, Condensed Matter Physics, Crystallography, chemistry, Cattle, Self-assembly, Gold, Protein adsorption