المؤلفون: Jackson LN, Zhou Y, Qiu S, Wang Q, Evers BM

المصدر: American Journal of Chinese Medicine; 2008, Vol. 36 Issue 5, p953-965, 13p

المؤلفون: Ha B; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA., Larsen KP; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.; Program in Biophysics, Stanford University, Stanford, CA, USA.; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA., Zhang J; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Fu Z; Department of Chemistry and Molecular Biophysics, Columbia University, New York, NY, USA.; Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, NY, USA., Montabana E; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Jackson LN; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Chen DH; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Puglisi EV; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA. epuglisi@stanford.edu.

المصدر: Nature communications [Nat Commun] 2021 May 04; Vol. 12 (1), pp. 2500. Date of Electronic Publication: 2021 May 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: HIV Reverse Transcriptase/*chemistry , HIV-1/*drug effects , RNA, Transfer, Lys/*chemistry , RNA, Viral/*chemistry , Reverse Transcriptase Inhibitors/*chemistry, Alkynes/chemistry ; Alkynes/pharmacology ; Benzoxazines/chemistry ; Benzoxazines/pharmacology ; Catalytic Domain ; Cryoelectron Microscopy ; Cyclopropanes/chemistry ; Cyclopropanes/pharmacology ; HIV Reverse Transcriptase/genetics ; HIV Reverse Transcriptase/metabolism ; HIV-1/enzymology ; HIV-1/genetics ; HIV-1/metabolism ; Models, Molecular ; Nevirapine/chemistry ; Nevirapine/pharmacology ; Nucleic Acid Conformation/drug effects ; RNA, Transfer, Lys/genetics ; RNA, Viral/genetics ; Reverse Transcriptase Inhibitors/pharmacology

المؤلفون: Krupkin M; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Jackson LN; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Ha B; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA., Puglisi EV; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: epuglisi@stanford.edu.

المصدر: Current opinion in structural biology [Curr Opin Struct Biol] 2020 Dec; Vol. 65, pp. 175-183. Date of Electronic Publication: 2020 Sep 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9107784 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-033X (Electronic) Linking ISSN: 0959440X NLM ISO Abbreviation: Curr Opin Struct Biol Subsets: MEDLINE

مواضيع طبية MeSH: Reverse Transcription*/drug effects, HIV-1/*genetics, Drug Design ; HIV-1/drug effects ; RNA, Transfer/genetics ; Ribonucleases/metabolism

المؤلفون: Larsen KP; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Program in Biophysics, Stanford University, Stanford, CA 94305, USA., Choi J; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Applied Physics, Stanford University, Stanford, CA 94305, USA., Jackson LN; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Kappel K; Program in Biophysics, Stanford University, Stanford, CA 94305, USA., Zhang J; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Ha B; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA., Chen DH; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Puglisi EV; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: epuglisi@stanford.edu.

المصدر: Journal of molecular biology [J Mol Biol] 2020 Jul 24; Vol. 432 (16), pp. 4499-4522. Date of Electronic Publication: 2020 Jun 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Point Mutation*, DNA, Viral/*chemistry , HIV Reverse Transcriptase/*metabolism , HIV-1/*genetics, Cryoelectron Microscopy ; DNA, Viral/metabolism ; Fluorescence Resonance Energy Transfer ; HIV Reverse Transcriptase/chemistry ; HIV-1/metabolism ; Models, Molecular ; Molecular Conformation ; Reverse Transcription ; Single Molecule Imaging

المؤلفون: Jackson LN; Departments of Pharmaceutical Sciences, University of California, Irvine, CA 92697-3958, USA., Chim N; Departments of Pharmaceutical Sciences, University of California, Irvine, CA 92697-3958, USA., Shi C; Departments of Pharmaceutical Sciences, University of California, Irvine, CA 92697-3958, USA., Chaput JC; Departments of Pharmaceutical Sciences, University of California, Irvine, CA 92697-3958, USA.; Department of Chemistry, University of California, Irvine, CA 92697-3958, USA.; Department of Molecular Biology and Biochemistry, University of California, CA 92697-3958, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2019 Jul 26; Vol. 47 (13), pp. 6973-6983.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*chemistry , DNA Polymerase I/*chemistry , Geobacillus stearothermophilus/*enzymology , RNA-Directed DNA Polymerase/*chemistry, Arabinonucleotides/metabolism ; Bacterial Proteins/isolation & purification ; Bacterial Proteins/metabolism ; Catalytic Domain ; Crystallography, X-Ray ; DNA Polymerase I/isolation & purification ; DNA Polymerase I/metabolism ; DNA, Bacterial/metabolism ; Models, Molecular ; Nucleic Acid Hybridization ; Nucleosides/metabolism ; Protein Binding ; Protein Conformation ; RNA-Directed DNA Polymerase/isolation & purification ; RNA-Directed DNA Polymerase/metabolism ; Structure-Activity Relationship ; Templates, Genetic

المؤلفون: Chim N; Departments of Pharmaceutical Sciences, University of California, Irvine, California., Jackson LN; Departments of Pharmaceutical Sciences, University of California, Irvine, California., Trinh AM; Departments of Pharmaceutical Sciences, University of California, Irvine, California., Chaput JC; Departments of Pharmaceutical Sciences, University of California, Irvine, California.; Department of Chemistry, University of California, Irvine, California.; Department of Molecular Biology and Biochemistry, University of California, Irvine, California.

المصدر: ELife [Elife] 2018 Oct 19; Vol. 7. Date of Electronic Publication: 2018 Oct 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: DNA/*biosynthesis , DNA Polymerase I/*chemistry , Escherichia coli/*enzymology, Biocatalysis ; Catalytic Domain ; Crystallography, X-Ray ; DNA/chemistry ; Protein Conformation

المؤلفون: Silva SR; Markey Cancer Center, University of Kentucky, Lexington, KY 40536-0093, USA., Zaytseva YY, Jackson LN, Lee EY, Weiss HL, Bowen KA, Townsend CM Jr, Evers BM

المصدر: Anticancer research [Anticancer Res] 2011 Apr; Vol. 31 (4), pp. 1153-60.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet ISSN: 1791-7530 (Electronic) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoid Tumor/*drug therapy , Liver Neoplasms/*drug therapy , PTEN Phosphohydrolase/*pharmacology , Serotonin/*metabolism, Animals ; Blotting, Western ; Carcinoid Tumor/metabolism ; Carcinoid Tumor/pathology ; Enzyme-Linked Immunosorbent Assay ; Female ; Immunoenzyme Techniques ; Liver Neoplasms/metabolism ; Liver Neoplasms/secondary ; Mice ; Mice, Nude ; PTEN Phosphohydrolase/antagonists & inhibitors ; Phosphoinositide-3 Kinase Inhibitors ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; RNA, Small Interfering/genetics ; Tumor Cells, Cultured

المؤلفون: Silva SR; Department of Surgery, The University of Texas Medical Branch, Galveston, TX, USA., Bowen KA, Rychahou PG, Jackson LN, Weiss HL, Lee EY, Townsend CM Jr, Evers BM

المصدر: International journal of cancer [Int J Cancer] 2011 Mar 01; Vol. 128 (5), pp. 1045-56.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasm Metastasis*, Carcinoid Tumor/*metabolism , Vascular Endothelial Growth Factor Receptor-2/*metabolism, Animals ; Base Sequence ; Carcinoid Tumor/pathology ; Cell Line, Tumor ; Cell Proliferation ; DNA Primers ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunohistochemistry ; Male ; Mice ; Mice, Nude ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction ; Vascular Endothelial Growth Factor A/metabolism

المؤلفون: Wang Q; Department of Surgery, The University of Kentucky, Lexington, KY 40506, USA., Zhou Y, Jackson LN, Johnson SM, Chow CW, Evers BM

المصدر: Molecular biology of the cell [Mol Biol Cell] 2011 Feb 01; Vol. 22 (3), pp. 412-20. Date of Electronic Publication: 2010 Dec 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation* , Signal Transduction*, NFATC Transcription Factors/*physiology , PTEN Phosphohydrolase/*genetics, Cyclin-Dependent Kinase Inhibitor p27/genetics ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Forkhead Box Protein O1 ; Forkhead Transcription Factors/metabolism ; Gene Expression Regulation ; Gene Knockdown Techniques ; Glycogen Synthase Kinase 3/metabolism ; Glycogen Synthase Kinase 3 beta ; HT29 Cells ; Humans ; NFATC Transcription Factors/genetics ; NFATC Transcription Factors/metabolism ; Oncogene Protein v-akt/metabolism ; PTEN Phosphohydrolase/metabolism ; Phosphorylation

المؤلفون: Wang X; Department of Surgery, The University of Texas Medical Branch, Galveston, Texas, USA., Jackson LN, Johnson SM, Wang Q, Evers BM

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2010 Aug; Vol. 9 (8), pp. 2389-98. Date of Electronic Publication: 2010 Jul 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Colorectal Neoplasms/*genetics , Histone Deacetylase Inhibitors/*pharmacology , Receptors, Neurotensin/*genetics, Butyrates/pharmacology ; Cell Line, Tumor ; Colorectal Neoplasms/enzymology ; Cyclooxygenase 2/biosynthesis ; Cyclooxygenase 2/genetics ; Down-Regulation/drug effects ; Enzyme Induction/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Glycogen Synthase Kinase 3/metabolism ; Glycogen Synthase Kinase 3 beta ; Humans ; Interleukin-8/genetics ; Interleukin-8/metabolism ; MAP Kinase Signaling System/drug effects ; Neurotensin/pharmacology ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Receptors, Neurotensin/metabolism