المؤلفون: Corry SM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., McCorry AM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Lannagan TR; Cancer Research UK, Beatson Institute for Cancer Research, Glasgow, UK., Leonard NA; Lambe Institute for Translational Research, College of Medicine Nursing and Health Sciences, National University of Ireland, Galway, Ireland.; Discipline of Pharmacology & Therapeutics, School of Medicine, National University of Ireland, Galway, Ireland., Fisher NC; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Byrne RM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Tsantoulis P; Université de Genève, Geneva, Switzerland., Cortes-Lavaud X; Cancer Research UK, Beatson Institute for Cancer Research, Glasgow, UK., Amirkhah R; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Redmond KL; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., McCooey AJ; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Malla SB; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Rogan E; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Sakhnevych S; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Gillespie MA; Cancer Research UK, Beatson Institute for Cancer Research, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., White M; Cancer Research UK, Beatson Institute for Cancer Research, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Richman SD; Leeds Institute of Medical Research, University of Leeds, Leeds, UK., Jackstadt RF; Cancer Research UK, Beatson Institute for Cancer Research, Glasgow, UK.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH) and Cancer Progression and Metastasis Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Campbell AD; Cancer Research UK, Beatson Institute for Cancer Research, Glasgow, UK., Maguire S; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., McDade SS; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Longley DB; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Loughrey MB; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.; Cellular Pathology, Belfast Health and Social Care Trust, Belfast, UK.; Centre for Public Health, Queens University Belfast, Belfast, UK., Coleman HG; Centre for Public Health, Queens University Belfast, Belfast, UK., Kerr EM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Tejpar S; Digestive Oncology Unit, University Ospital Gasthuisberg, Leuven, Belgium., Maughan T; Department of Oncology, University of Oxford, Oxford, UK., Leedham SJ; Wellcome Trust Centre Human Genetics, University of Oxford, Oxford, UK., Small DM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Ryan AE; Lambe Institute for Translational Research, College of Medicine Nursing and Health Sciences, National University of Ireland, Galway, Ireland.; Discipline of Pharmacology & Therapeutics, School of Medicine, National University of Ireland, Galway, Ireland., Sansom OJ; Cancer Research UK, Beatson Institute for Cancer Research, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Lawler M; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Dunne PD; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK p.dunne@qub.ac.uk.

مؤلفون مشاركون: S:CORT and ACRCelerate consortia

المصدر: Gut [Gut] 2022 Dec; Vol. 71 (12), pp. 2502-2517. Date of Electronic Publication: 2022 Apr 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers, Tumor*/genetics , Colonic Neoplasms*/pathology, Humans ; Stromal Cells/pathology ; Neoplasm Recurrence, Local/prevention & control ; Neoplasm Recurrence, Local/pathology ; Prognosis

المؤلفون: Weisshaar N; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Wu J; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Ming Y; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Madi A; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Hotz-Wagenblatt A; Core Facility Omics IT and Data Management, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Ma S; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Mieg A; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Hering M; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Zettl F; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Mohr K; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Schlimbach T; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Ten Bosch N; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Hertel F; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Müller L; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Byren H; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Wang M; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Borgers H; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Munz M; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Schmitt L; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., van der Hoeven F; Transgenic Service (W450), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Kloz U; Transgenic Service (W450), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Carretero R; DKFZ-Bayer Immunotherapeutic Lab, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Schleußner N; Cancer Progression and Metastasis (A013), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, University Heidelberg, 69120 Heidelberg, Germany., Jackstadt RF; Cancer Progression and Metastasis (A013), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Hofmann I; Division of Vascular Oncology and Metastasis (A190), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Core Facility Antibodies (W170), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Cui G; T Cell Metabolism Group (D192), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany.; Helmholtz Institute for Translational Oncology (HI-TRON), 55131 Mainz, Germany.

المصدر: Science immunology [Sci Immunol] 2022 May 27; Vol. 7 (71), pp. eabh1873. Date of Electronic Publication: 2022 May 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE

مواضيع طبية MeSH: CD8-Positive T-Lymphocytes* , Programmed Cell Death 1 Receptor*, RGS Proteins/*immunology, Animals ; Cell Differentiation ; Humans ; Immunotherapy ; Lymphocytes, Tumor-Infiltrating ; Mice

المؤلفون: Hutton C; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Heider F; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Blanco-Gomez A; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Banyard A; Flow Cytometry Core, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Kononov A; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Zhang X; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Karim S; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK., Paulus-Hock V; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK., Watt D; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK., Steele N; University of Michigan, Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, Ann Arbor, MI 48109, USA., Kemp S; Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA; Molecular and Cellular Pathology Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA., Hogg EKJ; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Kelly J; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Jackstadt RF; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK., Lopes F; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Menotti M; Cell Signalling, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Chisholm L; Molecular Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Lamarca A; Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK., Valle J; Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK; Institute of Cancer Sciences, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK., Sansom OJ; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Switchback Road, Garscube Estate, Glasgow G61 1QH, UK., Springer C; Drug Discovery Unit, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Malliri A; Cell Signalling, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Marais R; Molecular Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Pasca di Magliano M; University of Michigan, Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA., Zelenay S; Cancer Immunity and Inflammation, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK., Morton JP; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Switchback Road, Garscube Estate, Glasgow G61 1QH, UK., Jørgensen C; Systems Oncology, Cancer Research UK Manchester Institute, Alderley Park, Manchester SK10 4TG, UK. Electronic address: claus.jorgensen@cruk.manchester.ac.uk.

المصدر: Cancer cell [Cancer Cell] 2021 Sep 13; Vol. 39 (9), pp. 1227-1244.e20. Date of Electronic Publication: 2021 Jul 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Cancer-Associated Fibroblasts/*immunology , Carcinoma, Pancreatic Ductal/*immunology , Endoglin/*genetics , Pancreatic Neoplasms/*immunology , Single-Cell Analysis/*methods, Adaptive Immunity ; Animals ; Carcinoma, Pancreatic Ductal/genetics ; Case-Control Studies ; Cell Line, Tumor ; Cell Plasticity ; Endoglin/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Neoplasm Transplantation ; Pancreatic Neoplasms/genetics ; Tumor Microenvironment