نتائج البحث - "Jacques De Greve"

المساهمون: Centre de recherche en Biologie Cellulaire (CRBM), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Faculty of Sciences and Bioengineering Sciences, Biology, Medical Genetics, Basic (bio-) Medical Sciences, Faculty of Medicine and Pharmacy, Clinical sciences, Laboratory for Medical and Molecular Oncology, Department of Bio-engineering Sciences, Cellular and Molecular Immunology

المصدر: Oncogene
Oncogene, Nature Publishing Group, 2020, 39 (37), pp.6009-6023. ⟨10.1038/s41388-020-01396-8⟩

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cell division, [SDV]Life Sciences [q-bio], Aurora B kinase, Gene Expression, macromolecular substances, Deubiquitinating enzyme, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Cell Line, Tumor, Endopeptidases, Enzyme Stability, Serine, Genetics, Aurora Kinase B, Humans, Phosphorylation, Molecular Biology, Mitosis, ComputingMilieux_MISCELLANEOUS, biology, Cell Cycle, Cell Cycle Checkpoints, Cell cycle, Ubiquitin ligase, Cell biology, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, embryonic structures, Disease Progression, biology.protein, Interphase, Ubiquitin-Specific Proteases, biological phenomena, cell phenomena, and immunity, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9b3f8eca68c2f65c3ebf08acfad1b1
https://doi.org/10.1038/s41388-020-01396-8

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5

Dabrafenib plus trametinib in patients with BRAFV600E-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial

المساهمون: Neurology, Internal medicine, CCA - Cancer Treatment and quality of life, Medical Genetics, Clinical sciences, Laboratory for Medical and Molecular Oncology

المصدر: The Lancet Oncology, 23(1), 53-64. Lancet Publishing Group
Wen, P Y, Stein, A, van den Bent, M, de Greve, J, Wick, A, de Vos, F Y F L, von Bubnoff, N, van Linde, M E, Lai, A, Prager, G W, Campone, M, Fasolo, A, Lopez-Martin, J A, Kim, T M, Mason, W P, Hofheinz, R-D, Blay, J-Y, Cho, D C, Gazzah, A, Pouessel, D, Yachnin, J, Boran, A, Burgess, P, Ilankumaran, P, Gasal, E & Subbiah, V 2022, ' Dabrafenib plus trametinib in patients with BRAFV600E-mutant low-grade and high-grade glioma (ROAR) : a multicentre, open-label, single-arm, phase 2, basket trial ', The Lancet Oncology, vol. 23, no. 1, pp. 53-64 . https://doi.org/10.1016/S1470-2045(21)00578-7

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Adolescent, Neuroscience(all), Population, Oximes/administration & dosage, Brain Neoplasms/drug therapy, Isocitrate Dehydrogenase/genetics, Neutropenia, SDG 3 - Good Health and Well-being, Internal medicine, Glioma, Proto-Oncogene Proteins B-raf/genetics, Internal Medicine, medicine, Clinical endpoint, Humans, education, Aged, Trametinib, education.field_of_study, Pyridones/administration & dosage, business.industry, Antineoplastic Combined Chemotherapy Protocols/adverse effects, neurology, Dabrafenib, Middle Aged, Interim analysis, medicine.disease, Glioma/drug therapy, Cohort, young adult, Female, Pyrimidinones/administration & dosage, mutation, business, Imidazoles/administration & dosage, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fad158cf6a3776974f72e32f6f4611e
https://pure.eur.nl/en/publications/6534e7d9-0966-4ffb-83ef-1054a6161e37

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6

Abstract P1-10-05: Evaluation of germline whole exome sequencing of early breast cancer patients with triple negative breast cancer (TNBC) included in a prospective study of neoadjuvant chemotherapy (NAC) with epirubicin and cyclophosphamide (EC) and carboplatin-paclitaxel (PC) (BSMO 2014-01)

المؤلفون: Catherine Dopchie, Heidi Van den Bulck, P Glorieux, Christel Fontaine, Ahmad Awada, Lore Decoster, Jacques De Greve, Hans Wildiers, Sylvie De Brakeleer, V. Renard, Peter Vuylsteke, Erik Teugels

المصدر: Cancer Research. 80:P1-10

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a039b7d7c5d10eb600a8e3355f621d55
https://doi.org/10.1158/1538-7445.sabcs19-p1-10-05

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Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2)

المؤلفون: Maja J.A. de Jonge, Jan H.M. Schellens, Diane A.J. van der Biessen, Andre T. Brunetto, Agnes Jager, Johann S. de Bono, Joo Ern Ang, Martijn P. Lolkema, Jacques De Greve, Hendrik-Tobias Arkenau, Ruud van der Noll, Ilian Tchakov, Jos H. Beijnen, Marja Mergui-Roelvink, Serena Marchetti

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Clinical sciences, Medical Genetics, Medical Oncology, Laboratory for Medical and Molecular Oncology

المصدر: Investigational New Drugs, 38(4), 1096-1107. Kluwer Academic
Investigational New Drugs, 38. Kluwer Academic Publishers

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Neutropenia, Paclitaxel, Antineoplastic Agents, Capsules, Piperazines, Olaparib, Carboplatin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Phase I, SDG 3 - Good Health and Well-being, Internal medicine, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, Pharmacology (medical), Pharmacokinetics, Dosing, Fatigue, Aged, Pharmacology, business.industry, Area under the curve, Alopecia, Middle Aged, medicine.disease, Thrombocytopenia, 030104 developmental biology, PARP inhibitor, Tolerability, chemistry, 030220 oncology & carcinogenesis, Phthalazines, Female, business, Ovarian cancer, Tablets

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082dde6f0d16999d82d6405628aff352
https://doi.org/10.1007/s10637-019-00857-6

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8

Targeting the tyrosine kinase inhibitor-resistant mutant EGFR pathway in lung cancer without targeting EGFR?

المؤلفون: Philippe Giron, Jacques De Greve

المساهمون: Medical Genetics, Clinical sciences, Laboratory of Molecular and Medical Oncology, Basic (bio-) Medical Sciences, Faculty of Medicine and Pharmacy

المصدر: Translational Lung Cancer Research. 9:1-3

مصطلحات موضوعية: Medicine(all), business.industry, medicine.drug_class, EGFR, Mutant, medicine.disease, Tyrosine-kinase inhibitor, respiratory tract diseases, lung cancer, Editorial, Oncology, Tyrosine Kinase Inhibitor-Resistant Mutant EGFR Pathway, Cancer research, Medicine, Original Article, Egfr signaling, business, Lung cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c318651fb89ccc45cf639a02ceeb55
https://doi.org/10.21037/tlcr.2020.01.05

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CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition

المؤلفون: Rajendra Bahadur Shahi, Hugo Vandenplas, Carolien Eggermont, Philippe Giron, Jacques De Greve, Erik Teugels, Bram Boeckx, Diether Lambrechts, Sylvia De Brakeleer, Alfiah Noor, Amir Noeparast

المساهمون: Clinical sciences, Laboratory for Medical and Molecular Oncology, Faculty of Medicine and Pharmacy, Basic (bio-) Medical Sciences, Medical Genetics

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Lung Neoplasms, Somatic cell, medicine.disease_cause, ACTIVATION, Mice, Antineoplastic Agents, Immunological, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, PHOSPHORYLATION, Genetics & Heredity, Mutation, MEK inhibitor, B-RAF, COMBINED BRAF, MAP Kinase Kinase Kinases, C-RAF, Oncology, 030220 oncology & carcinogenesis, Phosphorylation, Life Sciences & Biomedicine, DABRAFENIB PLUS TRAMETINIB, Biochemistry & Molecular Biology, MAP Kinase Signaling System, Antineoplastic Agents, Biology, Brief Communication, Predictive markers, 03 medical and health sciences, Targeted therapies, MAPK PATHWAY, KINASE, KRAS, Genetics, medicine, Animals, Humans, Lung cancer, Protein Kinase Inhibitors, Molecular Biology, Science & Technology, HEK 293 cells, Cancer, Cell Biology, medicine.disease, Mice, Inbred C57BL, Proto-Oncogene Proteins c-raf, SORAFENIB, HEK293 Cells, 030104 developmental biology, Cancer research

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b673b3b333a2060d3e558cfe0e11de1
https://doi.org/10.1038/s41388-019-0866-7

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10

Unidentified cachexia patients in the oncologic setting: Cachexia UFOs do exist

المؤلفون: Elisabeth De Waele, Joeri J. Pen, Paolo Cotogni, Herbert D. Spapen, J. Demol, Manu L N G Malbrain, Jacques De Greve, Riccardo Caccialanza

المساهمون: Supporting clinical sciences, Intensive Care, Faculty of Medicine and Pharmacy, Internal Medicine Specializations, Clinical sciences, Medical Oncology, Laboratory of Molecular and Medical Oncology, Pathology/molecular and cellular medicine, Diabetes Clinic

المصدر: Nutrition. :200-204

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Delayed Diagnosis, Cachexia, Endocrinology, Diabetes and Metabolism, Psychological intervention, Nutritional Status, 030209 endocrinology & metabolism, Context (language use), Medical Oncology, Risk Assessment, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Neoplasms, Internal medicine, medicine, Humans, Medical nutrition therapy, Aged, Randomized Controlled Trials as Topic, Retrospective Studies, Cancer, Medicine(all), 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Body Weight, Retrospective cohort study, Middle Aged, medicine.disease, Data Accuracy, Hospitalization, Nutrition Assessment, Female, Nutrition Therapy, business, Abdominal surgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5d9f73e04d3f62120847b9a9c428d8
https://doi.org/10.1016/j.nut.2019.02.015

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