المؤلفون: Sudhakaran Prabakaran, Jagannathan Ns, Narendra Meena, Kethaki Prathivadi Bhayankaram

مصطلحات موضوعية: Open reading frame, Novel protein, Proteome, Computational biology, Biology, ORFS, Proteogenomics, ENCODE, Genome, Sequence (medicine)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02b166206ba0415fa7b69c9a5ca3ed3

المؤلفون: Sin WX; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Jagannathan NS; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore.; Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Teo DBL; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Kairi F; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Fong SY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Tan JHL; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Sandikin D; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Cheung KW; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Luah YH; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Wu X; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Raymond JJ; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore., Lim FLWI; Advanced Cell Therapy and Research Institute, Singapore (ACTRIS), Consortium for Clinical Research and Innovation, Singapore (CRIS), Singapore, Singapore.; Department of Haematology, Singapore General Hospital, Singapore, Singapore.; SingHealth Duke-NUS Oncology Academic Clinical Programme, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.; SingHealth Duke-NUS Cell Therapy Centre, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore., Lee YH; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore.; SingHealth Duke-NUS Cell Therapy Centre, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore., Seng MS; SingHealth Duke-NUS Oncology Academic Clinical Programme, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.; SingHealth Duke-NUS Cell Therapy Centre, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.; Department of Paediatric Haematology and Oncology, KK Women's and Children's Hospital, Singapore, Singapore., Soh SY; SingHealth Duke-NUS Oncology Academic Clinical Programme, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.; SingHealth Duke-NUS Cell Therapy Centre, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.; Department of Paediatric Haematology and Oncology, KK Women's and Children's Hospital, Singapore, Singapore., Chen Q; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ram RJ; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore. rajeev@mit.edu.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA. rajeev@mit.edu., Tucker-Kellogg L; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore. tuckerNUS@gmail.com.; Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. tuckerNUS@gmail.com., Birnbaum ME; Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore. mbirnb@mit.edu.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. mbirnb@mit.edu.; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA. mbirnb@mit.edu.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. mbirnb@mit.edu.

المصدر: Nature biomedical engineering [Nat Biomed Eng] 2024 Jun 04. Date of Electronic Publication: 2024 Jun 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-846X (Electronic) Linking ISSN: 2157846X NLM ISO Abbreviation: Nat Biomed Eng Subsets: MEDLINE

المؤلفون: Cheng RK; Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore, Singapore.; Neural Circuitry and Behavior Laboratory, Institute of Molecular and Cell Biology, A*STAR, 138673, Singapore, Singapore., Jagannathan NS; Centre for Computational Biology, and Duke-NUS Graduate Medical School Singapore, 8 College Road, 169857, Singapore, Singapore.; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School Singapore, 8 College Road, 169857, Singapore, Singapore., Kathrada AI; Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore, Singapore.; Department of Biomedical Engineering, National University of Singapore, 4 Engineering Drive 3, 117583, Singapore, Singapore., Jesuthasan S; Lee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore, Singapore. sureshj@ntu.edu.sg.; Neural Circuitry and Behavior Laboratory, Institute of Molecular and Cell Biology, A*STAR, 138673, Singapore, Singapore. sureshj@ntu.edu.sg., Tucker-Kellogg L; Centre for Computational Biology, and Duke-NUS Graduate Medical School Singapore, 8 College Road, 169857, Singapore, Singapore. tuckerNUS@gmail.com.; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School Singapore, 8 College Road, 169857, Singapore, Singapore. tuckerNUS@gmail.com.

المصدر: BMC neuroscience [BMC Neurosci] 2024 Apr 16; Vol. 25 (Suppl 1), pp. 22. Date of Electronic Publication: 2024 Apr 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100966986 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2202 (Electronic) Linking ISSN: 14712202 NLM ISO Abbreviation: BMC Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Habenula*/surgery , Habenula*/physiology , Laser Therapy*, Animals ; Dorsal Raphe Nucleus ; Zebrafish ; Computer Simulation

المؤلفون: Jagannathan NS; Cancer & Stem Cell Biology, and Centre for Computational Biology, Duke-NUS Medical School, 8 College Road, Singapore.; Singapore-MIT Alliance, Computation and Systems Biology Program, National University of Singapore, Singapore., Hogue CWV; Singapore-MIT Alliance, Computation and Systems Biology Program, National University of Singapore, Singapore.; Mechanobiology Institute, National University of Singapore, Singapore., Tucker-Kellogg L; Cancer & Stem Cell Biology, and Centre for Computational Biology, Duke-NUS Medical School, 8 College Road, Singapore.; Singapore-MIT Alliance, Computation and Systems Biology Program, National University of Singapore, Singapore.

المصدر: PLoS computational biology [PLoS Comput Biol] 2021 Jan 06; Vol. 17 (1), pp. e1008474. Date of Electronic Publication: 2021 Jan 06 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Protein Complex 2*/chemistry , Adaptor Protein Complex 2*/metabolism , Adaptor Proteins, Vesicular Transport*/chemistry , Adaptor Proteins, Vesicular Transport*/metabolism , Intrinsically Disordered Proteins*/chemistry , Intrinsically Disordered Proteins*/metabolism, Cell Membrane/chemistry ; Cell Membrane/metabolism ; Clathrin/chemistry ; Clathrin/metabolism ; Endocytosis/physiology ; Humans ; Molecular Docking Simulation ; Protein Binding ; Protein Conformation

المؤلفون: Jagannathan NS; Cancer and Stem Cell Biology Programme, Centre for Computational Biology, Duke-NUS Medical School, 169857 Singapore., Ihsan MO; Department of Biochemistry, National University of Singapore, 117596 Singapore.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, 117456 Singapore., Kin XX; Department of Biochemistry, National University of Singapore, 117596 Singapore., Welsch RE; Sloan School of Management and Center for Statistics and Data Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Clément MV; Department of Biochemistry, National University of Singapore, 117596 Singapore.; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, 117456 Singapore., Tucker-Kellogg L; Cancer and Stem Cell Biology Programme, Centre for Computational Biology, Duke-NUS Medical School, 169857 Singapore.

المصدر: Bioinformatics (Oxford, England) [Bioinformatics] 2020 May 01; Vol. 36 (9), pp. 2813-2820.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print Cited Medium: Internet ISSN: 1367-4811 (Electronic) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE

مواضيع طبية MeSH: Algorithms* , Breast Neoplasms*, Adaptation, Physiological ; Cells, Cultured ; Humans

المؤلفون: Zhang S; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore., Reljić B; Department of Biochemistry and Molecular Biology, The Bio21 Molecular Science & Biotechnology Institute, University of Melbourne, Melbourne, Australia., Liang C; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore., Kerouanton B; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore., Francisco JC; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore., Peh JH; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore., Mary C; SIB-Swiss Institute of Bioinformatics and Department of Microbiology and Molecular Medicine, Faculty of Medicine, Geneva University, Geneva, Switzerland., Jagannathan NS; Centre for Computational Biology, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore., Olexiouk V; Biobix, Lab of Bioinformatics and Computational Genomics, Department of Mathematical Modelling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium., Tang C; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore., Fidelito G; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore., Nama S; Institute of Medical Biology, A*STAR, Singapore, Singapore., Cheng RK; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Wee CL; Institute of Molecular and Cell Biology, A*STAR, Singapore, Singapore., Wang LC; Institute of Molecular and Cell Biology, A*STAR, Singapore, Singapore., Duek Roggli P; SIB-Swiss Institute of Bioinformatics, Lausanne, Switzerland., Sampath P; Skin Research Institute of Singapore, A*STAR, Singapore, Singapore., Lane L; SIB-Swiss Institute of Bioinformatics and Department of Microbiology and Molecular Medicine, Faculty of Medicine, Geneva University, Geneva, Switzerland., Petretto E; Centre for Computational Biology, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore., Sobota RM; Institute of Molecular and Cell Biology, A*STAR, Singapore, Singapore., Jesuthasan S; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore, Singapore., Tucker-Kellogg L; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Centre for Computational Biology, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore., Reversade B; Institute of Medical Biology, A*STAR, Singapore, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore, Singapore., Menschaert G; Biobix, Lab of Bioinformatics and Computational Genomics, Department of Mathematical Modelling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium., Sun L; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore., Stroud DA; Department of Biochemistry and Molecular Biology, The Bio21 Molecular Science & Biotechnology Institute, University of Melbourne, Melbourne, Australia., Ho L; Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore. lena@ho-lab.org.; Institute of Medical Biology, A*STAR, Singapore, Singapore. lena@ho-lab.org.

المصدر: Nature communications [Nat Commun] 2020 Mar 11; Vol. 11 (1), pp. 1312. Date of Electronic Publication: 2020 Mar 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Oxidative Phosphorylation*, Electron Transport Complex III/*metabolism , Mitochondria/*metabolism , Mitochondrial Proteins/*metabolism , Peptides/*metabolism , Zebrafish Proteins/*metabolism, Acidosis, Lactic/genetics ; Animals ; Animals, Genetically Modified ; Disease Models, Animal ; Female ; Gene Knockdown Techniques ; Growth Disorders/genetics ; Humans ; Male ; Metabolomics ; Mitochondrial Proteins/genetics ; Models, Animal ; Models, Biological ; Open Reading Frames/genetics ; Peptides/genetics ; Proteomics ; Zebrafish/genetics ; Zebrafish/growth & development ; Zebrafish Proteins/genetics

المؤلفون: Jagannathan NS; Duke-NUS Medical School, National University of Singapore, 8 College Road, Singapore 169857, Singapore, suhas@duke-nus.edu.sg., Hogue CWV, Tucker-Kellogg L

المصدر: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing [Pac Symp Biocomput] 2020; Vol. 25, pp. 183-194.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: World Scientific Country of Publication: United States NLM ID: 9711271 Publication Model: Print Cited Medium: Internet ISSN: 2335-6936 (Electronic) Linking ISSN: 23356928 NLM ISO Abbreviation: Pac Symp Biocomput Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Vesicular Transport* , Computational Biology*, Endocytosis ; Humans

المؤلفون: Alok A; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857 Singapore., Lei Z; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857 Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 169857 Singapore., Jagannathan NS; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857 Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 169857 Singapore., Kaur S; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857 Singapore., Harmston N; Centre for Computational Biology, Duke-NUS Medical School, 169857 Singapore., Rozen SG; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857 Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 169857 Singapore., Tucker-Kellogg L; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857 Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 169857 Singapore., Virshup DM; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857 Singapore david.virshup@duke-nus.edu.sg.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.

المصدر: Journal of cell science [J Cell Sci] 2017 May 01; Vol. 130 (9), pp. 1532-1544. Date of Electronic Publication: 2017 Mar 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*/genetics, Wnt Proteins/*metabolism , beta Catenin/*metabolism, Acetylation ; Clone Cells ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; HeLa Cells ; Humans ; Low Density Lipoprotein Receptor-Related Protein-6/metabolism ; Models, Biological ; Phosphorylation ; Protein Stability ; Receptors, G-Protein-Coupled/metabolism ; Stomach Neoplasms/genetics ; Up-Regulation/genetics

المؤلفون: Jagannathan NS; Centre for Computational Biology, and Duke-NUS Graduate Medical School Singapore, 8 College Road, Singapore., Tucker-Kellogg L; Centre for Computational Biology, and Duke-NUS Graduate Medical School Singapore, 8 College Road, Singapore; Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School Singapore, 8 College Road, Singapore; BioSystems and Micromechanics (BioSyM) Singapore-MIT Alliance for Research and Technology, 1 Create Way, Singapore. Electronic address: Lisa.Tucker-kellogg@duke-nus.edu.sg.

المصدر: Journal of biomechanics [J Biomech] 2016 May 24; Vol. 49 (8), pp. 1311-1320. Date of Electronic Publication: 2015 Dec 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0157375 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2380 (Electronic) Linking ISSN: 00219290 NLM ISO Abbreviation: J Biomech Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane Permeability* , Models, Biological*, Pressure Ulcer/*metabolism, Apoptosis ; Cell Death ; Cytoskeleton/physiology ; Humans ; Oxidative Stress