يعرض 1 - 10 نتائج من 17 نتيجة بحث عن '"James, Sipthorp"', وقت الاستعلام: 1.05s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

    المؤلفون: Goran Tomić, Clare Sheridan, Alice Y. Refermat, Marc P. Baggelaar, James Sipthorp, Bhuvana Sudarshan, Cory A. Ocasio, Alejandro Suárez-Bonnet, Simon L. Priestnall, Eleanor Herbert, Edward W. Tate, Julian Downward

    المصدر: Cell Reports, Vol 43, Iss 5, Pp 114224- (2024)

    مصطلحات موضوعية: CP: Cancer, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2211124724005527; https://doaj.org/toc/2211-1247

    URL الوصول: https://doaj.org/article/76f4fd25faf047aa857156b8f167bc94

    View record from ScienceDirect Full Text Finder
    أضف إلى المفضلة
  2. 2
    دورية أكاديمية
    CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells

    المؤلفون: Sougata Roy, James Sipthorp, Bidesh Mahata, Jhuma Pramanik, Marco L. Hennrich, Anne-Claude Gavin, Steven V. Ley, Sarah A. Teichmann

    المصدر: iScience, Vol 24, Iss 5, Pp 102485- (2021)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2589004221004533; https://doaj.org/toc/2589-0042

    URL الوصول: https://doaj.org/article/ad58f3e5b40640a693cfc545a2a5e267

    View record from ScienceDirect Full Text Finder
    أضف إلى المفضلة
  3. 3
    A palmitoyl transferase chemical genetic system to map ZDHHC-specificS-acylation

    المؤلفون: Cory A. Ocasio, Marc P. Baggelaar, James Sipthorp, Ana Losada de la Lastra, Jana Volarić, Christelle Soudy, Elisabeth M. Storck, Susana A. Palma-Duran, James I. MacRae, Goran Tomic, Lotte Carr, Julian Downward, Ulrike S. Eggert, Edward W. Tate

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ecc9036807dfa9291da193193120d746
    https://doi.org/10.1101/2023.04.18.537386

    أضف إلى المفضلة
  4. 4
    Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

    المؤلفون: Goran Tomić, Clare Sheridan, Alice Refermat, Marc Baggelaar, James Sipthorp, Bhuvana Sudarshan, Cory Ocasio, Alejandro Suarez-Bonnet, Simon Priestnall, Eleanor Herbert, Edward Tate, Julian Downward

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::43c917ec0073725d9e4211e4ce3a1305
    https://doi.org/10.21203/rs.3.rs-2648300/v1

    أضف إلى المفضلة
  5. 5
    5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit

    المؤلفون: Amy Monaghan, Paul Whiting, James Hillier, Svend Kjaer, Reinis R. Ruza, Jean-Paul Vincent, S. Frew, Paul V. Fish, L. Vecchia, William Mahy, James Sipthorp, Fredrik Svensson, Nicky J. Willis, Magda Bictash, Hannah Woodward, Patricia C. Salinas, Yuguang Zhao, E. Yvonne Jones

    المصدر: Journal of Medicinal Chemistry. 63:12942-12956

    مصطلحات موضوعية: 0303 health sciences, Reporter gene, animal structures, Carboxylesterase activity, Chemistry, Cell, Wnt signaling pathway, 01 natural sciences, Chemical space, Notum, 0104 chemical sciences, 3. Good health, Negative regulator, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Crystallography, Carboxylesterase, medicine.anatomical_structure, Drug Discovery, medicine, Molecular Medicine, 030304 developmental biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::deae46cf90f6f7beda225afadafa1e17
    https://doi.org/10.1021/acs.jmedchem.0c01391

    Find this issue from the American Chemical Society
    أضف إلى المفضلة
  6. 6
    Design of a potent, selective and brain penetrant inhibitor of Wnt-deactivating enzyme Notum by optimization of a crystallographic fragment hit

    المؤلفون: Nicky Willis, William Mahy, James Sipthorp, Yuguang Zhao, Hannah Woodward, Benjamin Atkinson, Elliott Bayle, Fredrik Svensson, Sarah Frew, Fiona Jeganathan, Amy Monaghan, Stefano Benvegnu, Sarah Jolly, Luca Vecchia, Reinis Ruza, Svend Kjaer, Steven Howell, Ambrosius Snidjers, Magda Bictash, Patricia Salinas, Jean-Paul Vincent, Yvonne Jones, Paul Whiting, Paul Fish

    مصطلحات موضوعية: animal structures

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8addc522ec8ef944de3c1786ccffb9ca
    https://doi.org/10.26434/chemrxiv-2022-f05w8

    أضف إلى المفضلة
  7. 7
    Design of a potent, selective, and brain-penetrant inhibitor of Wnt-deactivating enzyme Notum by optimization of a crystallographic fragment hit

    المؤلفون: Nicky J. Willis, William Mahy, James Sipthorp, Yuguang Zhao, Hannah L. Woodward, Benjamin N. Atkinson, Elliott D. Bayle, Fredrik Svensson, Sarah Frew, Fiona Jeganathan, Amy Monaghan, Stefano Benvegnù, Sarah Jolly, Luca Vecchia, Reinis R. Ruza, Svend Kjær, Steven Howell, Ambrosius P. Snijders, Magda Bictash, Patricia C. Salinas, Jean-Paul Vincent, E. Yvonne Jones, Paul Whiting, Paul V. Fish

    مصطلحات موضوعية: Model organisms, Chemical Biology & High Throughput, animal structures, FOS: Clinical medicine, Esterases, Neurosciences, Brain, Cell Biology, Crystallography, X-Ray, Biochemistry & Proteomics, Imaging, Signalling & Oncogenes, Drug Discovery, Molecular Medicine, Synthetic Biology, Enzyme Inhibitors, Wnt Signaling Pathway, Genetics & Genomics, Developmental Biology, Structural Biology & Biophysics, Computational & Systems Biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3474b8ac04a0b606e41a67edadf62c69

    أضف إلى المفضلة
  8. 8
    Structural analysis and development of Notum fragment screening hits

    المؤلفون: Yuguang Zhao, William Mahy, Nicky J. Willis, Hannah L. Woodward, David Steadman, Elliott D. Bayle, Benjamin N. Atkinson, James Sipthorp, Luca Vecchia, Reinis R. Ruza, Karl Harlos, Fiona Jeganathan, Stefan Constantinou, Artur Costa, Svend Kjær, Magda Bictash, Patricia C. Salinas, Paul Whiting, Jean-Paul Vincent, Paul V. Fish, E. Yvonne Jones

    مصطلحات موضوعية: Model organisms, Physiology, Cognitive Neuroscience, FOS: Clinical medicine, Neurosciences, General Medicine, Cell Biology, Crystallography, X-Ray, Biochemistry, Imaging, Signalling & Oncogenes, Synthetic Biology, Genetics & Genomics, Developmental Biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f547dc38fab64d9f08bf48b45b75fa9e

    أضف إلى المفضلة
  9. 9
    5-Phenyl-1,3,4-oxadiazol-2(3

    المؤلفون: William, Mahy, Nicky J, Willis, Yuguang, Zhao, Hannah L, Woodward, Fredrik, Svensson, James, Sipthorp, Luca, Vecchia, Reinis R, Ruza, James, Hillier, Svend, Kjær, Sarah, Frew, Amy, Monaghan, Magda, Bictash, Patricia C, Salinas, Paul, Whiting, Jean-Paul, Vincent, E Yvonne, Jones, Paul V, Fish

    المصدر: Journal of medicinal chemistry. 63(21)

    مصطلحات موضوعية: Male, Oxadiazoles, Binding Sites, Esterases, Administration, Oral, Molecular Dynamics Simulation, Crystallography, X-Ray, Mice, Inbred C57BL, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Blood-Brain Barrier, Drug Design, Microsomes, Liver, Animals, Humans, Enzyme Inhibitors, Wnt Signaling Pathway, Half-Life

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::07128c1ea3b73521973fe7fd4ebe3825
    https://pubmed.ncbi.nlm.nih.gov/33124429

    Find this issue from the American Chemical Society
    أضف إلى المفضلة
  10. 10
    CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells

    المؤلفون: Sarah A. Teichmann, Jhuma Pramanik, Anne-Claude Gavin, Sougata Roy, Marco L. Hennrich, Bidesh Mahata, Steven V. Ley, James Sipthorp

    المساهمون: Mahata, Bidesh [0000-0002-4506-0184], Ley, Steven [0000-0002-7816-0042], Teichmann, Sarah [0000-0002-6294-6366], Apollo - University of Cambridge Repository

    المصدر: iScience
    iScience, Vol 24, Iss 5, Pp 102485-(2021)
    bioRxiv
    iScience, Vol. 24, No 5 (2021) P. 102485

    مصطلحات موضوعية: 0301 basic medicine, Urologic Diseases, T cell, Science, Chemical biology, Context (language use), 32 Biomedical and Clinical Sciences, 02 engineering and technology, Biology, 3101 Biochemistry and Cell Biology, Article, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Immune system, medicine, 2.1 Biological and endogenous factors, Chemoproteomics, ddc:612, 030304 developmental biology, Cancer, 2 Aetiology, 0303 health sciences, Multidisciplinary, Prostate Cancer, 021001 nanoscience & nanotechnology, medicine.disease, 3211 Oncology and Carcinogenesis, 3. Good health, Cell biology, 3204 Immunology, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Pregnenolone, Generic health relevance, 0210 nano-technology, Function (biology), CD8, medicine.drug, 31 Biological Sciences

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78a4c0d66cabfb1576159ec0a796427

    View record from ScienceDirect
    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS – أرسل هذا البحث بالبريد الإلكتروني – حفظ البحث – جدول التنبيهات: لا شيء