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المؤلفون: Andrew Clear, Anna Castleton, James D. Cavenagh, Heather Oakervee, Farideh Miraki-Moud, Pedro R. Cutillas, Bella Patel, Koorosh Korfi, Linda Ariza McNaughton, C. Xintaropoulou, F. Mardakheh, Dominique Bonnet, Ania Wilczynska, I. Pislariu, Ai Nagano, Michael J Austin, Martyn T. Smith, Karla J. Suchacki, John G. Gribben, Mariarita Calaminici, Q. Heydt, David Taussig, B. Peck, William P. Cawthorn
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Heydt, Q, Xintaropoulou, C, Clear, A, Austin, M, Pislariu, I, Miraki-Moud, F, Cutillas, P, Korfi, K, Calaminici, M, Cawthorn, W P, Oldknow, K, Nagano, A, Gribben, J G, Smith, M, Cavenagh, J D, Oakervee, O, Castleton, A, Taussig, D, Peck, B, Wilczynska, A, McNaughton, L, Bonnett, D, Mardakheh, F & Patel, B 2021, ' Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence ', Nature Communications . https://doi.org/10.1038/s41467-021-25540-4مصطلحات موضوعية: Adult, Cancer microenvironment, Proteome, Cell Survival, medicine.medical_treatment, Biopsy, Science, General Physics and Astronomy, Disease, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Pathogenesis, chemistry.chemical_compound, Mice, Young Adult, Cell quiescence, Bone Marrow, Stress, Physiological, Adipocyte, 3T3-L1 Cells, hemic and lymphatic diseases, medicine, Adipocytes, Animals, Humans, Cell Lineage, Chemotherapy, Human Biology & Physiology, Multidisciplinary, Acute lymphocytic leukaemia, Stem Cells, Induction chemotherapy, General Chemistry, Middle Aged, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Tumour Biology, Survival Analysis, medicine.anatomical_structure, chemistry, Cancer research, Bone marrow
وصف الملف: application/pdf
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المؤلفون: Richard G. Jenner, Tushhar Dadaga, Roger G. Owen, Sally F. Barrington, Matthew Streetly, Marquita Camilleri, William R. Wilson, Rakesh Popat, Jonathan Sive, Gavin Pang, Karthik Ramasamy, Laura Clifton-Hadley, Ceri Bygrave, Elizabeth H Phillips, Kwee Yong, Lucy Pike, James D. Cavenagh, Michael A Chapman
المصدر: British Journal of Haematology
Phillips, E 2020, ' COVID-19 and myeloma clinical research – experience from the CARDAMON clinical trial ', British Journal of Haematology, vol. 192, no. 1, pp. e14-e16 . https://doi.org/10.1111/bjh.17168مصطلحات موضوعية: medicine.medical_specialty, 2019-20 coronavirus outbreak, clinical trials, Manchester Cancer Research Centre, Coronavirus disease 2019 (COVID-19), business.industry, ResearchInstitutes_Networks_Beacons/mcrc, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Multiple Myeloma/complications, Hematology, Dexamethasone/therapeutic use, Clinical trial, Online Only, Clinical research, myeloma, Cyclophosphamide/therapeutic use, COVID‐19, Internal medicine, Correspondence, COVID-19/complications, Humans, Medicine, Oligopeptides/therapeutic use, business, Stem Cell Transplantation
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المؤلفون: Michael A Chapman, Rakesh Popat, Reuben Benjamin, Roger G. Owen, Sumaiya Kamora, Tushhar Dadaga, Ceri Bygrave, William R. Wilson, James D. Cavenagh, Gavin Pang, Karthik Ramasamy, Ruth M. de Tute, Lydia Eccersley, Richard G. Jenner, Kwee Yong, Marquita Camilleri, Jonathan Sive, Laura Clifton-Hadley, Sandra Hassan, Matthew Streetly, Fenella Willis, Elizabeth H Phillips
المصدر: Clinical Lymphoma Myeloma and Leukemia. 21:S2-S3
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), business.industry, cons, Hematology, medicine.disease, Carfilzomib, Discontinuation, chemistry.chemical_compound, chemistry, Internal medicine, Medicine, Cyclophosphamide/Dexamethasone, business, Adverse effect, Multiple myeloma, Lenalidomide, medicine.drug
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المؤلفون: Richard G. Jenner, Roger G. Owen, Lydia Eccersley, Laura Clifton-Hadley, Rakesh Popat, William R. Wilson, Elizabeth H Phillips, Selina J Chavda, Kwee Yong, Marie Scully, Michael Sheaff, Matthew Streetly, Gavin Pang, Karthik Ramasamy, Ceri Bygrave, Andres Virchis, James D. Cavenagh, Jonathan Sive, Gordon Cook, Sumaiya Kamora, Marquita Camilleri, Maria José Cuadrado, Michael A Chapman, Reuben Benjamin
المصدر: Phillips, E 2021, ' Thrombotic microangiopathy in untreated myeloma patients receiving carfilzomib, cyclophosphamide and dexamethasone on the CARDAMON study. ', British Journal of Haematology, vol. 193, no. 4, pp. 750-760 . https://doi.org/10.1111/bjh.17377
مصطلحات موضوعية: Male, medicine.medical_specialty, Thrombotic microangiopathy, Cyclophosphamide, thrombocytopenia, Gastroenterology, Dexamethasone, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Refractory, Internal medicine, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, Dosing, thrombotic haemolytic anaemias, Aged, clinical trials, carfilzomib, Manchester Cancer Research Centre, business.industry, Thrombotic Microangiopathies, ResearchInstitutes_Networks_Beacons/mcrc, Acute kidney injury, Hematology, Acute Kidney Injury, Middle Aged, medicine.disease, Carfilzomib, myeloma, chemistry, 030220 oncology & carcinogenesis, Premedication, Female, business, Multiple Myeloma, Oligopeptides, 030215 immunology, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Tushhar Dadaga, Rakesh Popat, William R. Wilson, Richard G. Jenner, Ruth M. de Tute, Michael A Chapman, Kwee Yong, Selina J Chavda, Ceri Bygrave, Gavin Pang, Karthik Ramasamy, Marquita Camilleri, Maria del Mar Cuadrado, Roger G. Owen, James D. Cavenagh, Jonathan Sive, Sumaiya Kamora, Laura Clifton-Hadley, Matthew Streetly, Elizabeth H Phillips
المصدر: Blood. 138:2911-2911
مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Immunology, Cell Biology, Hematology, Newly diagnosed, medicine.disease, Biochemistry, Carfilzomib, chemistry.chemical_compound, Autologous stem-cell transplantation, chemistry, Internal medicine, Medicine, Cyclophosphamide/Dexamethasone, business, Multiple myeloma
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6d61de0bf0f6b06c75ba114c611779db
https://doi.org/10.1182/blood-2021-147771 -
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المؤلفون: Marquita Camilleri, Lalita Banerjee, Elizabeth H Phillips, Selina J Chavda, Richard G. Jenner, Reuben Benjamin, Matthew Streetly, William R. Wilson, Sally F. Barrington, Sally Moore, Tushhar Dadaga, Manil Subesinghe, Maria del Mar Cuadrado, Rakesh Popat, Roger G. Owen, Kwee Yong, Sumaiya Kamora, Ceri Bygrave, Lucy Pike, Michael A Chapman, Laura Clifton-Hadley, Lydia Eccersley, Gavin Pang, Karthik Ramasamy, James D. Cavenagh, Jonathan Sive
المصدر: Blood. 138:2750-2750
مصطلحات موضوعية: Oncology, medicine.medical_specialty, PET-CT, business.industry, Immunology, Cell Biology, Hematology, medicine.disease, Biochemistry, Carfilzomib, chemistry.chemical_compound, Maintenance therapy, chemistry, Internal medicine, medicine, business, Multiple myeloma, Disease burden
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::66eec1fb31e33c3050cb075780eb4fc4
https://doi.org/10.1182/blood-2021-150177 -
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المؤلفون: Juho J. Miettinen, David Taussig, Szilvia Krizsán, Csaba Bödör, Karina Close, Wencheng Yin, Jean-Baptiste Cazier, Sylvie D. Freeman, Findlay Bewicke-Copley, Krister Wennerberg, Alun Parsons, Peter Van Loo, Naeem Khan, Jun Wang, Doriana Di Bella, Marianne Grantham, Kimmo Porkka, Farideh Miraki-Moud, Ana Rio-Machin, Pedro R. Cutillas, Dominique Bonnet, Jiexin Zheng, Jonas Demeulemeester, Christopher P. Middleton, William Grey, Janet Matthews, Kevin Rouault-Pierre, Jude Fitzgibbon, James D. Cavenagh, Caroline A. Heckman, Pedro Casado-Izquierdo, Hannah Armes
المصدر: Blood. 136:39-40
مصطلحات موضوعية: Poor risk, Immunology, Myeloid leukemia, Cell Biology, Hematology, Computational biology, Biology, Biochemistry, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Multi omics, Profiling (information science), 030215 immunology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c79a65417ce119e2122d1eca1c18ee5d
https://doi.org/10.1182/blood-2020-141345 -
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المؤلفون: William R. Wilson, M. Cuadrado, Rakesh Popat, Tushhar Dadaga, James D. Cavenagh, Gavin Pang, Elizabeth H Phillips, Marquita Camilleri, Matthew Streetly, Laura Clifton-Hadley, Michael A Chapman, Richard G. Jenner, Ruth M. de Tute, Roger G. Owen, Kwee Yong, Sumaiya Kamora, Karthink Ramasamy, Ceri Bygrave, Selina J Chavda, Jonathan Sive
المصدر: Journal of Clinical Oncology. 39:8000-8000
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Newly diagnosed, medicine.disease, Carfilzomib, chemistry.chemical_compound, Autologous stem-cell transplantation, chemistry, Internal medicine, medicine, Cyclophosphamide/Dexamethasone, business, Multiple myeloma
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::38d4d2faaf8cf280439829cbffad3353
https://doi.org/10.1200/jco.2021.39.15_suppl.8000 -
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المؤلفون: Zita Borbényi, Suddhasatta Acharyya, Karen W.L. Yee, Je-Hwan Lee, Massimo Breccia, S. Ide, Árpád Illés, Alan Macwhannell, Carlos Graux, Miklos Egyed, Nancy Zhu, David Valcárcel, James D. Cavenagh, Reinhard Stauder, Huda Salman, Daniel J. DeAngelo, Mikkael A. Sekeres, M. Marker, Oliver G. Ottmann, G. Garcia-Manero, Lucien Gazi, Pierre Fenaux
المصدر: Leukemia
مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Myeloid, Indoles, Administration, Oral, Kaplan-Meier Estimate, Hydroxamic Acids, Gastroenterology, chemistry.chemical_compound, 0302 clinical medicine, Bone Marrow, Antineoplastic Combined Chemotherapy Protocols, Panobinostat, Aged, 80 and over, Leukemia, Myelomonocytic, Chronic, Hematology, Orvostudományok, Middle Aged, 3. Good health, Leukemia, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Azacitidine, Original Article, Female, medicine.drug, Adult, medicine.medical_specialty, Maximum Tolerated Dose, Chronic myelomonocytic leukemia, Klinikai orvostudományok, 03 medical and health sciences, Internal medicine, medicine, Humans, neoplasms, Aged, business.industry, Myelodysplastic syndromes, medicine.disease, Demethylating agent, Regimen, 030104 developmental biology, chemistry, Myelodysplastic Syndromes, business
وصف الملف: application/pdf
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المؤلفون: Robert Kerrin Hills, Amanda F. Gilkes, James D. Cavenagh, Nigel H. Russell, Mark J. Levis, Lars Kjeldsen, Rosemary E. Gale, Gail Jones, Heiko Konig, Michael R. Grunwald, Steven Knapper, Alan K. Burnett, Ian Thomas
مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Clinical Trials and Observations, Kaplan-Meier Estimate, Pharmacology, Biochemistry, 0302 clinical medicine, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Medicine, Child, Lestaurtinib, Hazard ratio, Hematopoietic Stem Cell Transplantation, Hematology, Induction Chemotherapy, Middle Aged, Chemotherapy regimen, Leukemia, Myeloid, Acute, 030220 oncology & carcinogenesis, Child, Preschool, Female, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Gemtuzumab ozogamicin, Immunology, Carbazoles, Disease-Free Survival, 03 medical and health sciences, Young Adult, Internal medicine, Humans, Furans, Protein Kinase Inhibitors, Aged, Proportional Hazards Models, business.industry, Surrogate endpoint, Induction chemotherapy, Consolidation Chemotherapy, Cell Biology, 030104 developmental biology, fms-Like Tyrosine Kinase 3, Fms-Like Tyrosine Kinase 3, Mutation, business
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a433153489c228c979215ef15852fbb
https://doi.org/10.1182/blood-2016-07-730648