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المؤلفون: Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K. Strickland, Andrey G. Sarafanov
المصدر: Journal of Thrombosis and Haemostasis. 20:2255-2269
مصطلحات موضوعية: Lipoproteins, LDL, Binding Sites, Factor VIII, Receptors, LDL, Humans, Hematology, Deuterium, Ligands, Low Density Lipoprotein Receptor-Related Protein-1, Protein Binding
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المؤلفون: Andrey Tovchigrechko, Yasuhiro Ikeda, Claire Dobson, Andrew Park, Susan Wilson, Rebecca A. Halpin, Changshou Gao, Carrie R. Sowers, Albert E. Schmelzer, James H. Kurasawa
المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 330-340 (2020)مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, viruses, Genetic enhancement, Transgene, Sf9, Biology, Virus, Viral vector, law.invention, 03 medical and health sciences, Transduction (genetics), baculovirus, 0302 clinical medicine, law, Genetics, lcsh:QH573-671, Molecular Biology, insect cell, lcsh:Cytology, AAV, Cell biology, lcsh:Genetics, Chemically defined medium, 030104 developmental biology, 030220 oncology & carcinogenesis, Recombinant DNA, Molecular Medicine, Original Article
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المؤلفون: Svetlana A Shestopal, Andrey G Sarafanov, Ekaterina S. Marakasova, James H. Kurasawa, Haarin Chun, Elena Karnaukhova, Dudley K. Strickland, Nancy E. Hernandez, Philip Olivares, Gabriela U. Hassink
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Protein Folding, Circular dichroism, LRP1, low-density receptor-related protein 1, DNA Mutational Analysis, Very Low-Density Lipoprotein Receptor, Ligands, Biochemistry, LDL, low-density lipoprotein, LDL-Receptor Related Protein-Associated Protein, Receptor, CD, circular dichroism, CR, complement-type repeat, biology, Chemistry, SE-FPLC, size-exclusion fast protein liquid chromatography, molecular chaperone, ASPP, ammonium sulfate/potassium phosphate (buffer), KD, dissociation constant, LRP1, ApoE3, apolipoprotein E3 protein, Cell biology, Molecular Docking Simulation, LDLR, low-density lipoprotein receptor, factor VIII (FVIII), Protein folding, Low Density Lipoprotein Receptor-Related Protein-1, Protein Binding, Research Article, Repetitive Sequences, Amino Acid, In silico, SPR, surface plasmon resonance, LDL-receptor-related protein-associated protein, ER, endoplasmic reticulum, 03 medical and health sciences, Humans, low-density lipoprotein (LDL), protein expression, Molecular Biology, RAP, LDL-receptor related protein-associated protein, EDTA, ethylenediaminetetraacetic acid, 030102 biochemistry & molecular biology, LDL-receptor related protein-associated protein (RAP), fungi, Cell Biology, 030104 developmental biology, Receptors, LDL, vLDLR, very low-density lipoprotein receptor, LDL receptor, RU, response units, biology.protein, sense organs
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdca564b873d705b6974821f416bc0a1
https://doi.org/10.1016/j.jbc.2021.100842 -
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المؤلفون: Jian-Jiang Hao, John H. McVey, Yideng Liang, James H. Kurasawa, Mikhail V Ovanesov, Elena Karnaukhova, Timothy K Lee, M. Lin, Andrey G Sarafanov, Svetlana A Shestopal
المصدر: Journal of Thrombosis and Haemostasis. 15:709-720
مصطلحات موضوعية: 0301 basic medicine, Tyrosine sulfation, DNA, Complementary, Glycosylation, Genetic Vectors, CHO Cells, 030204 cardiovascular system & hematology, Protein Engineering, Protein Structure, Secondary, Cell Line, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, 0302 clinical medicine, Thrombin, Affinity chromatography, Cricetinae, hemic and lymphatic diseases, Complementary DNA, medicine, Animals, Humans, Codon, chemistry.chemical_classification, Factor VIII, Chinese hamster ovary cell, Lentivirus, Hematology, Molecular biology, Peptide Fragments, Amino acid, 030104 developmental biology, chemistry, Cell culture, Mutation, Tyrosine, medicine.drug
وصف الملف: text
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المؤلفون: Yelena Lazdun, Eric Tu, Susan Wilson, Kelly McGlinchey, Katie Streicher, Leslie Wetzel, Zachary A. Cooper, James H. Kurasawa, Karen Coffman
المصدر: Cancer Research. 80:911-911
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Combination therapy, biology, business.industry, T cell, Wild type, Cancer, medicine.disease, Granzyme B, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, Cell culture, medicine, Cancer research, biology.protein, Antibody, business, CD8, 030215 immunology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad20d79a25e1936f8457c1efe470c692
https://doi.org/10.1158/1538-7445.am2020-911 -
6Mapping the Binding Region on the Low Density Lipoprotein Receptor for Blood Coagulation Factor VIII
المؤلفون: James H. Kurasawa, Svetlana A Shestopal, Andrey G Sarafanov, Elena Karnaukhova, Timothy K Lee, Evi Struble
المصدر: Journal of Biological Chemistry. 288:22033-22041
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, animal diseases, Molecular Sequence Data, Plasma protein binding, Immunoglobulin light chain, Binding, Competitive, Biochemistry, LDL-receptor-related protein-associated protein, law.invention, law, hemic and lymphatic diseases, Protein Interaction Mapping, Humans, Amino Acid Sequence, LDL-Receptor Related Protein-Associated Protein, Binding site, Receptor, Molecular Biology, Peptide sequence, Binding Sites, Factor VIII, Sequence Homology, Amino Acid, biology, Chemistry, Circular Dichroism, food and beverages, nutritional and metabolic diseases, Cell Biology, Surface Plasmon Resonance, Molecular biology, Peptide Fragments, Recombinant Proteins, Kinetics, Receptors, LDL, Mutation, Protein Structure and Folding, LDL receptor, Mutagenesis, Site-Directed, biology.protein, Recombinant DNA, lipids (amino acids, peptides, and proteins), Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b048310bb6884adf212e781b105ec347
https://doi.org/10.1074/jbc.m113.468108 -
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المؤلفون: Andrey G Sarafanov, James H. Kurasawa, Svetlana A Shestopal, Timothy K Lee, Naveen Jha, Mikhail V Ovanesov
المصدر: Protein Expression and Purification. 88:201-206
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Insecta, Gene Expression, Video microscopy, Spodoptera, Cell Line, law.invention, law, hemic and lymphatic diseases, Animals, Single-chain variable fragment, Blood Coagulation, Factor VIII, biology, Chemistry, Ligand binding assay, Thrombin, Ligand (biochemistry), biology.organism_classification, Molecular biology, Recombinant Proteins, Cell culture, Factor Xa, Recombinant DNA, biology.protein, Antibody, Baculoviridae, Plasmids, Single-Chain Antibodies, Biotechnology
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المؤلفون: Hervé Chambost, James H. Kurasawa, Irina A. Demina, Andrey G Sarafanov, Mikhail A. Panteleev, Fazly I. Ataullakhanov, Nadezhda A. Podoplelova, Marie-Christine Alessi, Anastasia N. Sveshnikova, Sergey A. Vasil’ev
المساهمون: Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), ALESSI, Marie-Christine, Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, 1858 (6), pp.1216-27مصطلحات موضوعية: 0301 basic medicine, [SDV.MHEP.HEM] Life Sciences [q-bio]/Human health and pathology/Hematology, [SDV]Life Sciences [q-bio], Biophysics, 030204 cardiovascular system & hematology, Biochemistry, Annexin V, Membrane-dependent reaction, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biopolymers, Blood platelets, Coagulation factor X, Annexin, Prothrombinase, Humans, Platelet, Computer Simulation, Platelet activation, Binding site, Phosphatidylserine, Phospholipids, Chemistry, Vesicle, Factor X, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, Cell Biology, Surface Plasmon Resonance, Blood coagulation, Platelet Activation, [SDV] Life Sciences [q-bio], 030104 developmental biology, Membrane, Factor Xa
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50c2cf8d1790d127ed0ea5e67cb773d
https://hal.archives-ouvertes.fr/hal-01478132 -
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المؤلفون: Samuel A. Woodle, Svetlana A Shestopal, Andrey G Sarafanov, Mikhail V Ovanesov, Timothy K Lee, James H. Kurasawa
المصدر: Biochemistry. 54(2)
مصطلحات موضوعية: Biochemistry, law.invention, Mice, law, hemic and lymphatic diseases, Protein Interaction Mapping, Animals, Surface plasmon resonance, LDL-Receptor Related Protein-Associated Protein, Factor VIIIa, Mice, Inbred BALB C, Binding Sites, Factor VIII, biology, Chemistry, Ligand, Molecular biology, Recombinant Proteins, Macroglobulin, Chaperone (protein), LDL receptor, biology.protein, Recombinant DNA, lipids (amino acids, peptides, and proteins), Antibody, Protein Multimerization, Low Density Lipoprotein Receptor-Related Protein-1, Lipoprotein, Protein Binding
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المؤلفون: Jian-Jiang Hao, Yideng Liang, Min Lin, John H. McVey, Mikhail V Ovanesov, James H. Kurasawa, Andrey G Sarafanov, Timothy K Lee, Svetlana A Shestopal, Elena Karnaukhova
المصدر: Blood. 128:3765-3765
مصطلحات موضوعية: chemistry.chemical_classification, Tyrosine sulfation, Immunology, Cell Biology, Hematology, Biochemistry, Molecular biology, Amino acid, Open reading frame, Thrombin, chemistry, Complementary DNA, medicine, Synonymous substitution, Polyacrylamide gel electrophoresis, Peptide sequence, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::419bfbe5132ed07427c59240fb6d58dd
https://doi.org/10.1182/blood.v128.22.3765.3765