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المؤلفون: Roy Helmy, W. Peter Wuelfing, Kausik K. Nanda, Olivier Mozziconacci, James H. Small, Leonardo R. Allain
المصدر: Journal of Pharmaceutical Sciences. 108:1466-1475
مصطلحات موضوعية: Active ingredient, Oxidative degradation, Chemistry, Chemistry, Pharmaceutical, Drug Compounding, Drug Storage, Pharmaceutical Science, Hydrogen Peroxide, 02 engineering and technology, Oxidants, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Degradation (geology), Drug product, Indicators and Reagents, Product (category theory), Biochemical engineering, 0210 nano-technology, Oxidation-Reduction, Chromatography, High Pressure Liquid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f96cda9c569fad829e044bfb260912
https://doi.org/10.1016/j.xphs.2018.10.059 -
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المؤلفون: James H. Small, Fengyuan Yang, Chengbin Huang, Yongchao Su, Chad D. Brown, Andrew M. Farrington, James DiNunzio, Gary E. Martin
المصدر: Pharmaceutical Research. 37
مصطلحات موضوعية: Hot Temperature, Magnetic Resonance Spectroscopy, Pyrrolidines, Vinyl Compounds, Materials science, Nifedipine, Drug Compounding, Molecular Conformation, Pharmaceutical Science, 02 engineering and technology, 030226 pharmacology & pharmacy, Miscibility, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Rheology, Pharmacology (medical), Clotrimazole, Pharmacology, chemistry.chemical_classification, Active ingredient, Drug Carriers, Rheometry, Viscosity, Organic Chemistry, Hot Melt Extrusion Technology, Polymer, Triazoles, 021001 nanoscience & nanotechnology, Elasticity, Amorphous solid, Drug Liberation, chemistry, Chemical engineering, Molecular Medicine, Extrusion, 0210 nano-technology, Dispersion (chemistry), Biotechnology
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المؤلفون: Sandra Guillon, Ming-Tain Lai, Jean-Christophe Meillon, Min Xu, Izzat T. Raheem, Rachid Rahali, Thierry Convard, James H. Small, Francois-Rene Alexandre, Kerry L. Fillgrove, Houcine Rahali, Cyril B. Dousson
المصدر: Journal of Medicinal Chemistry. 61:9218-9228
مصطلحات موضوعية: Protein Conformation, Stereochemistry, Chemistry Techniques, Synthetic, 010402 general chemistry, Antiviral Agents, 01 natural sciences, Cell Line, Inhibitory Concentration 50, chemistry.chemical_compound, Deoxyadenosine, Drug Discovery, medicine, Animals, Humans, Tissue Distribution, IC50, Deoxyadenosines, Nucleoside analogue, 010405 organic chemistry, Chemistry, Assay, Phosphoramidate, Prodrug, HIV Reverse Transcriptase, Rats, 0104 chemical sciences, Molecular Docking Simulation, Mechanism of action, HIV-1, Reverse Transcriptase Inhibitors, Molecular Medicine, medicine.symptom, Nucleoside, medicine.drug
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المؤلفون: James H. Small, Michael Lowinger, Robert O. Williams, James D. Ormes, Yongchao Su, Feng Zhang
المصدر: International journal of pharmaceutics. 568
مصطلحات موضوعية: Thermoplastic, Polyurethanes, Pharmaceutical Science, Ibuprofen, 02 engineering and technology, 030226 pharmacology & pharmacy, Permeability, Diffusion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Emtricitabine, Polyurethane, chemistry.chemical_classification, Drug Implants, Atomic force microscopy, Dextrans, Membranes, Artificial, Polymer, 021001 nanoscience & nanotechnology, Microstructure, Molecular Weight, Membrane, chemistry, Chemical engineering, Permeability (electromagnetism), 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, Porosity, Fluorescein-5-isothiocyanate, Macromolecule, Metoprolol
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المؤلفون: Xiaodong Li, Tamara D. Cabalu, Cheri M Maciolek, Donghui Cui, Wen Liu, Ka Lai Yee, Thomayant Prueksaritanont, Sheri Smith, Bo Liu, Jacqueline B. McCrea, James H. Small
المصدر: Xenobiotica. 46:882-895
مصطلحات موضوعية: Adult, Male, Health, Toxicology and Mutagenesis, Metabolite, Pharmacology, Toxicology, 030226 pharmacology & pharmacy, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Oral administration, In vivo, Sleep Initiation and Maintenance Disorders, Humans, CYP3A4, Chemistry, Suvorexant, Antagonist, Azepines, General Medicine, Triazoles, Healthy Volunteers, Orexin receptor, Orexin, Sleep Aids, Pharmaceutical, Female, 030217 neurology & neurosurgery
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المؤلفون: Jonathan Steele, Yong Liu, Liam Evans, Ronald de Vries, Richard Phipps, Cheri M Maciolek, Roy Helmy, Steven L. Colletti, Iain Martin, Gary E. Martin, Douglas C. Beshore, Natasa Pajkovic, Headley Williams, Rhys Salter, Yong Gong, James H. Small
المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 49(8)
مصطلحات موضوعية: 0301 basic medicine, Health, Toxicology and Mutagenesis, Metabolite, Toxicology, 030226 pharmacology & pharmacy, Biochemistry, Chemical synthesis, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biotransformation, Humans, Liver microsomes, Pharmacology, Safety studies, Bacteria, Drug discovery, General Medicine, 030104 developmental biology, chemistry, Pharmaceutical Preparations, Metabolome, Oxidation-Reduction, Drug metabolism
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المؤلفون: Julie A. O'Brien, George D. Hartman, Brian C. Magliaro, James H. Small, Mark E. Fraley, Sarah L. Huszar, Pete H. Hutson, Marlene A. Jacobson, Kerry L. Fillgrove, Cuyue Tang, Jason M. Uslaner, Robert M. Garbaccio, Edward J. Brnardic, Yuhsin Kuo
المصدر: ACS Medicinal Chemistry Letters. 1:406-410
مصطلحات موضوعية: business.industry, medicine.medical_treatment, Organic Chemistry, Drug Discovery, Allosteric regulation, Medicine, Pharmacology, Metabotropic glutamate receptor 2, Receptor, business, Antipsychotic, Biochemistry, G protein-coupled receptor
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المؤلفون: James H. Small, Douglas A. Loy, Cy Fujimoto, Mariya Khiterer, Theresa M. McIntire, Kenneth J. Shea, Christopher J. Cornelius
المصدر: Chemistry of Materials. 18:3665-3673
مصطلحات موضوعية: chemistry.chemical_classification, Materials science, General Chemical Engineering, General Chemistry, Nuclear magnetic resonance spectroscopy, Porosimetry, Sulfonic acid, Conductivity, Microstructure, Polyelectrolyte, Membrane, chemistry, Chemical engineering, Polymer chemistry, Materials Chemistry, Hybrid material
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المؤلفون: Brigitta M. Baugher, James H. Small, James V. Beach, Douglas A. Loy, Roger A. Assink, Joseph Tran, Kenneth J. Shea
المصدر: Chemistry of Materials. 11:3333-3341
مصطلحات موضوعية: Reaction mechanism, Silanes, Bridging (networking), General Chemical Engineering, Chemical modification, General Chemistry, chemistry.chemical_compound, Monomer, chemistry, Polymerization, Polymer chemistry, Materials Chemistry, Molecule, Sol-gel
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المؤلفون: Joseph P. Carpenter, Peter K. Dorhout, Raef Shaltout, John Greaves, James H. Small, Todd M. Alam, Douglas A. Loy, Kenneth J. Shea
المصدر: Journal of the American Chemical Society. 121:5413-5425
مصطلحات موضوعية: Bicyclic molecule, Dimer, General Chemistry, Nuclear magnetic resonance spectroscopy, Condensation reaction, Biochemistry, Catalysis, Silsesquioxane, chemistry.chemical_compound, Colloid and Surface Chemistry, Monomer, chemistry, Polymerization, Intramolecular force, Polymer chemistry