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المؤلفون: K. S. Currie, R. W. DeSimone, S. A. Mitchell, D. A. Pippin, James W. Darrow
المصدر: Combinatorial Chemistry & High Throughput Screening. 7:473-493
مصطلحات موضوعية: Drug discovery, Bioactive molecules, Organic Chemistry, Binding properties, Receptors, Cell Surface, Nanotechnology, General Medicine, Computational biology, Biology, Computer Science Applications, Structure-Activity Relationship, Pharmaceutical Preparations, Drug Design, Terminology as Topic, Drug Discovery, Animals, Humans, Structure based, Identification (biology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90869655da19a7c5e4847c739066acb7
https://doi.org/10.2174/1386207043328544 -
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المؤلفون: James W. Darrow, D. G. Drueckhammer
المصدر: ChemInform. 25
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Nanotechnology, General Medicine, Phosphonate, Combinatorial chemistry
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3
المصدر: ChemInform. 30
مصطلحات موضوعية: Agonist, Chemistry, Stereochemistry, medicine.drug_class, Covalent bond, Structural similarity, medicine, Potency, General Medicine, Ligand (biochemistry), Receptor, Small molecule
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المؤلفون: Wyne P. Lee, Scott A. Mitchell, James W. Darrow, Mercedesz Balazs, James Barbosa, Richard A.D. Carano, Wendy B. Young, J. Andrew Whitney, Juan Zhang, Anthony M. Giannetti, Christine Yu, Kevin S. Currie, Hong Rong, Peter Gribling, Douglas R. Davies, Ronald E. Ferrando, Sarah G. Hymowitz, Karin Reif, Randall Mark Jones, Brandon J. Bravo, Laura DeForge, Patricia Maciejewski, Lauri Diehl, Kropf Jeffrey E, Julie Di Paolo, Tao Huang, Kai H. Barck, Sherry Yeh, Vincent Hurez, Steven L. Gallion, Bart L. Staker
المصدر: Nature chemical biology. 7(1)
مصطلحات موضوعية: Inflammatory arthritis, medicine.medical_treatment, Interleukin-1beta, Arthritis, Arthritis, Rheumatoid, Mice, immune system diseases, hemic and lymphatic diseases, medicine, Agammaglobulinaemia Tyrosine Kinase, Bruton's tyrosine kinase, Animals, Myeloid Cells, Phosphorylation, Molecular Biology, Protein Kinase Inhibitors, B cell, Autoantibodies, Cell Proliferation, B-Lymphocytes, biology, Cell growth, Interleukin-6, Tumor Necrosis Factor-alpha, Cell Biology, Protein-Tyrosine Kinases, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Arthritis, Experimental, Enzyme Activation, medicine.anatomical_structure, Cytokine, Immunology, Benzamides, biology.protein, Cancer research, Tumor necrosis factor alpha, Tyrosine kinase
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المؤلفون: James W. Darrow, Aaron Bourret, Robert Desimone, Jin-Ming Xiong, Patricia Maciejewski, Seung H. Lee, David C. Eustice, Mihaela Diana Danca, Douglas A. Pippin, David R. Brittelli, Kropf Jeffrey E, Peter Blomgren, Melissa Hill-Drzewi, Kevin S. Currie, Lisa Elkin, Steven L. Gallion, Scott A. Mitchell
المصدر: Bioorganicmedicinal chemistry letters. 19(24)
مصطلحات موضوعية: animal structures, Angiogenesis, Clinical Biochemistry, Receptor, EphB4, Pharmaceutical Science, Angiogenesis Inhibitors, Biochemistry, Receptor tyrosine kinase, chemistry.chemical_compound, Growth factor receptor, Cell Line, Tumor, Drug Discovery, Humans, Urea, Receptor, Molecular Biology, Protein Kinase Inhibitors, biology, Phenylurea Compounds, Organic Chemistry, Imidazoles, Angiopoietin receptor, Vascular endothelial growth factor, chemistry, Pyrazines, embryonic structures, biology.protein, Cancer research, Molecular Medicine, Signal transduction, Platelet-derived growth factor receptor
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المؤلفون: Terry P. Lybrand, Elizabeth M. Hadac, Elizabeth E. Sugg, Eric S. Dawson, Laurence J. Miller, James W. Darrow
مصطلحات موضوعية: Agonist, Models, Molecular, medicine.drug_class, Stereochemistry, Context (language use), CHO Cells, Photoaffinity Labels, In Vitro Techniques, Ligands, Cholecystokinin receptor, Devazepide, Article, Rats, Sprague-Dawley, Benzodiazepines, Benzophenones, Radioligand Assay, Structure-Activity Relationship, Cricetulus, Cricetinae, Drug Discovery, medicine, Animals, Binding site, Receptor, Pancreas, Chromatography, High Pressure Liquid, Binding Sites, Chemistry, Cell Membrane, Stereoisomerism, Small molecule, Protein Structure, Tertiary, Rats, Receptor, Cholecystokinin A, Transmembrane domain, Molecular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d60e29e09bcfd954df13c0eb4b50f7
https://europepmc.org/articles/PMC2528300/ -
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المصدر: Bioorganicmedicinal chemistry letters. 8(22)
مصطلحات موضوعية: Agonist, medicine.drug_class, Structural similarity, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Photoaffinity Labels, Ligands, Biochemistry, Cell Line, Structure-Activity Relationship, Drug Discovery, medicine, Structure–activity relationship, Animals, Receptor, Molecular Biology, Bicyclic molecule, Chemistry, Organic Chemistry, Ligand (biochemistry), Small molecule, Rats, Receptor, Cholecystokinin A, Molecular Probes, Molecular Medicine, Receptors, Cholecystokinin
